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| 1 | History of the temperature-dependence of susceptibility and its implications: Preliminary results along an E-W transect of the Chinese Loess Plateau显示文摘An investigation of rock magnetic properties using the temperature-dependence ofsusceptibility (TDS) and the coercivity of different IRM components was conducted on samples ofthe Malan loess (L1) and the last interglacial soil (S1) along an E-W transect of the Chinese LoessPlateau. We find that the behavior of the TDS is useful in identifying maghemite (γ-Fe2O3) in bothloess and paleosol, and that it can be used as a new proxy of the degree of pedogenesis, which isclosely linked to climatic conditions. Based on results from the TDS, we conclude that (1) thedetrital magnetite grains predominate in the L1 unit to the west of Liupan Mts, where theweathering and pedogenetic processes were weakest; (2) a comparable degree of pedogenesisexists in the L1 at the east of the Liupan Mts and the S1 at the west of the Liupan Mts; (3) a higherconcentration of maghemite is found in the S1 unit at the eastern sections, suggesting that the localclimate was warmer and more humid in this interval. In addition, we propose that TDSmeasurements can be used as a rapid means of determining the reliability of the paleomagneticsecular variation (PSV) record in loess/poleoso/sequenees. | ZHU Rixiang LIN Mian PAN Yongxin 1) Institute of Geophysics. Chinese Academy of Sciences. Beijing 100101 2) Institute of Mechanism. Chinese Academy of Sciences, Beijing 100080 | 1999 | Chinese Science Bulletin1999，44，S1： | 24 |
| 2 | PROCESS CONTROL OF THE SAND WAVE MIGRATION IN BEIBU GULF OF THE SOUTH CHINA SEA显示文摘Based on the environment characteristics of the Beibu Gulf of South China Sea, a quasi-three-dimensional physical model is built.By coupling the bottom boundary layer with the two-dimensional tidal current field near the seabed surface, the quasi-three-dimensional hydrodynamic numerical simulation is carried out.The sand wave migration process is dealt with by coupling the hydrodynamic model with the sediment transport model.The computational results are shown to be in good agreement with the observed data, which indicates that the quasi-three-dimensional physical model can be used to simulate the migration process for small scale sand waves.Then, based on measured data, the evolution of the sand wave migration is investigated.An effective formula is developed to predict the migration rate, in which not only the effects of the environment but also the features of sand waves are considered. | LI yong LIN Mian JIANG Wen-bing FAN Feng-xin | 2011 | Journal of Hydrodynamics2011，23，4： | 15 |
| 3 | Smoking and Its Relation to Metabolic Status among Chinese Adults: Analysis of a Nationwide Survey显示文摘Objective To update the estimated prevalence rates of smoking and examine major metabolic diseases associated with smoking status in Chinese adults. Methods Using a complex, multistage, probability sampling design, we recruited a nationally representative sample of 98,658 Chinese adults aged ≥18 years in 2010. Information on current, former, never, and passive smoking status was obtained using a standard questionnaire. All estimates were weighted to represent the overall Chinese adult population. Results The estimated proportion of current smokers was 28.3% for Chinese adults aged ≥18 years. The corresponding values of former and passive smokers were 5.1% and 21.4%, respectively. Additionally, former smokers were found to have a less favorable metabolic risk profile among all categories of smoking status in both men and women. The prevalence of metabolic diseases such as diabetes and hypertension also increased with a greater number of smoking pack-years in men. Conclusion The prevalences of current smoking and passive smoking remain high in Chinese adults. | DING Lin XU Yu WANG Li Min JIANG Yong ZHANG Mei LI Yi Chong LU Jie Li XU Min WANG Tian Ge LI Mian ZHAO Zhi Yun DAI Meng WANG Wei Qing ZHAO Wen Hua WANG Lin Hong BI Yu Fang NING Guang 无 | 2016 | Biomedical and Environmental Sciences2016，29，9： | 5 |
| 4 | Association between Lipoprotein(a) Levels and Metabolic Syndrome in a Middle-aged and Elderly Chinese Cohort显示文摘Objective The association between lipoprotein(a)[Lp(a)] levels and metabolic syndrome(MetS) remains uncertain, especially in the Asian population. The purpose of this study was to demonstrate the association between Lp(a) levels and MetS in a middle-aged and elderly Chinese cohort. Methods A cross-sectional study of 10,336 Chinese adults aged 40 years or older was conducted in Jiading District, Shanghai, China. Logistic regression analysis was used to evaluate the association between serum Lp(a) levels and MetS. Results In the overall population, 37.5% of participants had MetS. Compared with individuals in the lowest quartile of serum Lp(a) levels, those in the highest quartile had a lower prevalence of MetS(30.9% vs. 46.9%, P for trend < 0.0001). Multivariate logistic regression analyses showed that compared with participants in the bottom quartile of serum Lp(a) levels, those in the top quartile had decreased odds ratio(OR) for prevalent MetS [multivariate-adjusted OR 0.45(95% confidence interval 0.39-0.51);P < 0.0001]. Additionally, Lp(a) level was conversely associated with the risk of central obesity, high fasting glucose, high triglycerides, and low HDL cholesterol, but not with hypertension. Stratified analyses suggested that increasing levels of Lp(a) was associated with decreased risk of MetS in all the subgroups. Conclusion Serum Lp(a) level was inversely associated with the risk of prevalent MetS in a middle-aged and elderly Chinese cohort. | WU Xue Yan LIN Lin Qi Hong Yan DU Rui HU Chun Yan MA Li Na PENG Kui LI Mian XU Yu XU Min CHEN Yu Hong LU Jie Li BI Yu Fang WANG Wei Qing NING Guang | 2019 | Biomedical and Environmental Sciences2019，32，7： | 5 |
| 5 | Monoterpene and tetrahydronaphthene derivatives from Senecio argunensis显示文摘二新混合物, senarguines A 和 B,从 Senecio argunensis 被孤立。他们分别地作为(Z)-3-ethylidene-9-hydroxyl-9-methyl-6,7-dioxaspiro 被识别[4.4 ] nonane-5,8– dione (1 ) 和 3,6,6-trimethyl 6,7,8-tetrahydronaphtha-[1,2b ] 呋喃(2 ) 根据光谱数据。 | Chao Feng Zhang Ning Li Lin Li Mian Zhang | 2009 | Chinese Chemical Letters2009，20，5： | 4 |
| 6 | WAVE-BODY INTERACTIONS FOR A SURFACE-PIERCING BODY IN WATER OF FINITE DEPTH显示文摘Nonlinear wave-body interactions for a stationary surface-piercing body in water of finite depth with flat and sloping bottoms are simulated in a two-dimensional numerical wave tank,which is constructed mainly based on the spatially averaged Navier-Stokes equations with the model for simulating the turbulence.The equations are discretized based on the finite volume method and the scheme of the pressure implicit splitting of operators is employed to solve the Navier-Stokes equations.By using the force time histories,the mean and higher-harmonic force components are calculated.The computational results are shown to be in good agreement with experimental and numerical results of other researchers.Then,the horizontal force,the vertical force and the moment on the surface-piercing body under nonlinear regular waves with flat and sloping bottoms are obtained.The results indicate that the bottom topographies have a significant influence on the wave loads on the surface-piercing body. | LI Yong LIN Mian | 2010 | Journal of Hydrodynamics2010，22，6： | 4 |
| 7 | The Lum inescence Properties of M'type of YTaO_4∶Eu显示文摘A series of Eu 3+ doped of Mtype of yttrium orthotantalate Y 1-x Eu x TaO 4( x =0—0.30) was sythesized. The influence of activator concentration on luminescence properties was studied in detail. The strong evidence from excitation spectra, emission spectra and diffusive reflection spectra of this system shows that there is energy transfer from TaO 3- 4 to Eu 3+ via the charge transfer and spectral overlap. | LI Bo, GU Zhen nan ** , DONG Yi , LIN Jian hua and SU Mian zeng (Chemistry Department, State key Laboratory of Rare Earth Materials Chemistry and Applications , Peking University, Bejing 100871, P. R. China) (Received Dec. 26, 1 | 1999 | Chemical Research in Chinese Universities1999，15，3： | 3 |
| 8 | Serum uric acid and risk of incident diabetes in middle-aged and elderly Chinese adults: prospective cohort study显示文摘The association between serum uric acid and the risk of incident diabetes in Chinese adults remains unknown.This study aimed to investigate this association in a community-dwelling population aged≥40 years in Shanghai,China.Oral glucose tole3rance test was conducted during baseline and follow-up visits.Relative risk regression was utilized to examine the associations between baseline gender-specific serum uric acid levels and incident diabetes risk.A total of 613(10.3%)incident diabetes cases were identified during the follow-up visit after 4.5 years.Fasting plasma glucose,postload glucose,and glycated hemoglobin A1c during the follow-up visit progressively increased across the sex-specific quartiles of serum uric acid(all Ps<0.05).The incidence rate of diabetes increased across the quartiles of serum uric acid(7.43%,8.77%,11.47%,and 13.43%).Multivariate adjusted regression analysis revealed that individuals in the highest quartile had 1.36-fold increased risk of diabetes compared with those in the lowest quartile of serum uric acid(odds ratio(95%confidence interval)=1.36(1.06−1.73)).Stratified analysis indicated that the association was only observed in women.Accordingly,serum uric acid was associated with the increased risk of incident diabetes among middle-aged and elderly Chinese women. | Di Cheng Chunyan Hu Rui Du Hongyan Qi Lin Lin Xueyan Wu Lina Ma Kui Peng Mian Li Min Xu Yu Xu Yufang Bi Weiqing Wang Yuhong Chen Jieli Lu | 2020 | Frontiers of Medicine2020，14，6： | 3 |
| 9 | Association between Coronary Atherosclerotic Plaque Composition and Cardiovascular Disease Risk显示文摘Objective The objective of this study is to determine whether coronary atherosclerotic plaque composition is associated with cardiovascular disease(CVD) risk in Chinese adults. Methods We performed a cross-sectional analysis in 549 subjects without previous diagnosis or clinical symptoms of CVD in a community cohort of middle-aged Chinese adults. The participants underwent coronary computed tomography(CT) angiography for the evaluation of the presence and composition of coronary plaques. CVD risk was evaluated by the Framingham risk score(FRS) and the 10-year atherosclerotic cardiovascular disease(ASCVD) risk score. Results Among the 549 participants, 267(48.6%) had no coronary plaques, 201(36.6%) had noncalcified coronary plaques, and 81(14.8%) had calcified or mixed coronary plaques. The measures of CVD risk including FRS and ASCVD risk score and the likelihood of having elevated FRS significantly increased across the groups of participants without coronary plaques, with noncalcified coronary plaques, and with calcified or mixed coronary plaques. However, only calcified or mixed coronary plaques were significantly associated with an elevated ASCVD risk score [odds ratio(OR) 2.41; 95% confidence interval(CI) 1.09-5.32] compared with no coronary plaques, whereas no significant association was found for noncalcified coronary plaques and elevated ASCVD risk score(OR 1.25; 95% CI 0.71-2.21) after multivariable adjustment. Conclusion Calcified or mixed coronary plaques might be more associated with an elevated likelihood of having CVD than noncalcified coronary plaques. | LI Lin WANG Long LIU Shan Shan ZHAO Zhi Yun LI Mian WANG Tian Ge XU Min LU Jie Li CHEN Yu Hong WANG Shuang Yuan DAI Meng HOU Ya Nan WU Xue Yan MA Li Na WANG Wei Qing XU Yu BI Yu Fang | 2019 | Biomedical and Environmental Sciences2019，32，2： | 3 |
| 10 | Electrochemical Lithium Storage Performance of Molten Salt Derived V_(2)SnC MAX Phase显示文摘MAX phases are gaining attention as precursors of two-dimensional MXenes that are intensively pursued in applications for electrochemical energy storage.Here,we report the preparation of V_(2)SnC MAX phase by the molten salt method.V_(2)SnC is investigated as a lithium storage anode,showing a high gravimetric capacity of 490 mAh g−1 and volumetric capacity of 570 mAh cm^(−3) as well as superior rate performance of 95 mAh g^(−1)(110 mAh cm^(−3))at 50 C,surpassing the ever-reported performance of MAX phase anodes.Sup-ported by operando X-ray diffraction and density functional theory,a charge storage mechanism with dual redox reaction is proposed with a Sn-Li(de)alloying reaction that occurs at the edge sites of V_(2)SnC particles where Sn atoms are exposed to the electrolyte followed by a redox reaction that occurs at V_(2)C layers with Li.This study offers promise of using MAX phases with M-site and A-site elements that are redox active as high-rate lithium storage materials. | Youbing Li Guoliang Ma Hui Shao Peng Xiao Jun Lu Jin Xu Jinrong Hou Ke Chen Xiao Zhang Mian Li Per OÅPersson Lars Hultman Per Eklund Shiyu Du Zhifang Chai Zhengren Huang Na Jin Jiwei Ma Ying Liu Zifeng Lin Qing Huang | 2021 | Nano-Micro Letters2021，13，10： | 2 |
| 11 | High-density lipoprotein regulates angiogenesis by long non-coding RNA HDRACA显示文摘Normal high-density lipoprotein(nHDL)can induce angiogenesis in healthy individuals.However,HDL from patients with coronary artery disease undergoes various modifications,becomes dysfunctional(dHDL),and loses its ability to promote angiogenesis.Here,we identified a long non-coding RNA,HDRACA,that is involved in the regulation of angiogenesis by HDL.In this study,we showed that nHDL downregulates the expression of HDRACA in endothelial cells by activating WW domain-containing E3 ubiquitin protein ligase 2,which catalyzes the ubiquitination and subsequent degradation of its transcription factor,Kruppel-like factor 5,via sphingosine 1-phosphate(S1P)receptor 1.In contrast,dHDL with lower levels of S1P than nHDL were much less effective in decreasing the expression of HDRACA.HDRACA was able to bind to Ras-interacting protein 1(RAIN)to hinder the interaction between RAIN and vigilin,which led to an increase in the binding between the vigilin protein and proliferating cell nuclear antigen(PCNA)mRNA,resulting in a decrease in the expression of PCNA and inhibition of angiogenesis.The expression of human HDRACA in a hindlimb ischemia mouse model inhibited the recovery of angiogenesis.Taken together,these findings suggest that HDRACA is involved in the HDL regulation of angiogenesis,which nHDL inhibits the expression of HDRACA to induce angiogenesis,and that dHDL is much less effective in inhibiting HDRACA expression,which provides an explanation for the decreased ability of dHDL to stimulate angiogenesis. | Zhi-Wei Mo Yue-Ming Peng Yi-Xin Zhang Yan Li Bi-Ang Kang Ya-Ting Chen Le Li Mary GSorci-Thomas Yi-Jun Lin Yang Cao Si Chen Ze-Long Liu Jian-Jun Gao Zhan-Peng Huang Jia-Guo Zhou Mian Wang Guang-Qi Chang Meng-Jie Deng Yu-Jia Liu Zhen-Sheng Ma Zuo-Jun Hu Yu-Gang Dong Zhi-Jun Ou Jing-Song Ou | 2023 | Signal Transduction and Targeted Therapy2023，8，9： | 1 |
| 12 | Engineered gold/black phosphorus nanoplatforms with remodeling tumor microenvironment for sonoactivated catalytic tumor theranostics显示文摘The imbalance between oxidants and antioxidants in cancer cells would evoke oxidative stress-induced cell death,which has been demonstrated to be highly effective in treating malignant tumors.Sonodynamic therapy(SDT)adopts ultrasound(US)as the excitation source to induce the production of reactive oxygen species(ROS),which emerges as a noninvasive therapeutic strategy with deep tissue penetration depth and high clinical safety.Herein,we construct novel sonoactivated oxidative stress amplification nanoplatforms by coating MnO_(2) on Au nanoparticle-anchored black phosphorus nanosheets and decorating soybean phospholipid subsequently(Au/BP@MS).The Au/BP@MS exhibit increased ROS generation efficiency under US irradiation in tumor tissues due to Au/BP nanosensitizer-induced improvement of electron-hole separation as well as MnO_(2)-mediated O_(2) generation and GSH depletion,thus leading to notable inhibition effect on tumor growth.Moreover,tumor microenvironment-responsive biodegradability of Au/BP@MS endows them with enhanced magnetic resonance imaging guidance and clinical potential for cancer theranostics. | Ting Chen Weiwei Zeng Changjun Tie Mian Yu Huisong Hao Yang Deng Qianqian Li Hairong Zheng Meiying Wu Lin Mei | 2022 | Bioactive Materials2022，7，4： | 1 |
| 13 | Power Modeling and Optimization for OLED Displays 显示文摘 | MIAN Dong LIN Zhong | 2012 | IEEE Transactions on Mobile Computing(S1536-1233)2012，9，11： | 1 |
| 14 | Multi-platform omics analysis reveals molecular signature for COVID-19 pathogenesis,prognosis and drug target discovery显示文摘Disease progression prediction and therapeutic drug target discovery for Coronavirus disease 2019(COVID-19)are particularly important,as there is still no effective strategy for severe COVID-19 patient treatment.Herein,we performed multi-platform omics analysis of serial plasma and urine samples collected from patients during the course of COVID-19.Integrative analyses of these omics data revealed several potential therapeutic targets,such as ANXA1 and CLEC3B.Molecular changes in plasma indicated dysregulation of macrophage and suppression of T cell functions in severe patients compared to those in non-severe patients.Further,we chose 25 important molecular signatures as potential biomarkers for the prediction of disease severity.The prediction power was validated using corresponding urine samples and plasma samples from new COVID-19 patient cohort,with AUC reached to 0.904 and 0.988,respectively.In conclusion,our omics data proposed not only potential therapeutic targets,but also biomarkers for understanding the pathogenesis of severe COVID-19. | Yuming Li Guixue Hou Haibo Zhou Yanqun Wang Hein Min Tun Airu Zhu Jingxian Zhao Fei Xiao Shanwen Lin Dongdong Liu Dunrong Zhou Lang Mai Lu Zhang Zhaoyong Zhang Lijun Kuang Jiao Guan Qiushi Chen Liyan Wen Yanjun Zhang Jianfen Zhuo Fang Li Zhen Zhuang Zhao Chen Ling Luo Donglan Liu Chunke Chen Mian Gan Nanshan Zhong Jincun Zhao Yan Ren Yonghao Xu | 2021 | Signal Transduction and Targeted Therapy2021，6，5： | 1 |
| 15 | SKI pathways inducing progression of human melanoma显示文摘 | Reed J A Lin Q Chen D Mian I S Medrano E E | 2005 | Cancer Metastasis Rev2005，24，： | 1 |
| 16 | Characterization and determination of genipin- 1 - β - gentiobioside in gardenia fruit by high - performance liquid chromatography with ultraviolet detection following electrospray ionization mass spectrometry 显示文摘 | Hongxia Liu Lin Gao Mian Liu Qin Li Yuyang Jiang Shusheng Zhang | 2006 | Microchemical J2006，84，： | 1 |
| 17 | Serum Fetuin-A Levels and Thyroid Function in Middle-aged and Elderly Chinese显示文摘Serum fetuin-A levels are reportedly elevated in hyperthyroidism. However, there are few relevant epidemiologic studies. We conducted a cross-sectional study in Songnan community, China in 2009 to investigate the association between serum fetuin-A concentrations and thyroid function. A total of 2,984 participants aged 40 years and older were analyzed. Multivariable linear regression analysis revealed that serum fetuin-A concentrations were positively associated with log(free triiodothyronine) and were inversely associated with log(thyroid peroxidase antibody) after adjustment(both P < 0.05). Compared with the participants in the lowest tertile of free triiodothyronine and free thyroxine level, those in the highest tertile had higher fetuin-A concentrations. Additionally, high serum fetuin-A concentrations were related to high thyroid function(odds ratio 1.27, 95% confidence interval 1.01-1.61), after adjustment for conventional risk factors. | DENG Xin Ru DING Lin WANG Tian Ge XU Min LU Jie Li LI Mian ZHAO Zhi Yun CHEN Yu Hong BI Yu Fang XU Yi Ping XU Yu | 2017 | Biomedical and Environmental Sciences2017，30，6： | 1 |
| 18 | Study on the variation of added mass and its application to the calculation of amplitude response for a circular cylinder at lock-in 显示文摘 | Wang Yi Chen Weimin Lin Mian | 2007 | China Ocean Engineering2007，21，3： | 1 |
| 19 | Characterization and determination of genipin-1-β-gentiobioside in gardenia fruit by high-performance liquid chromatography with ultraviolet de tection following electrospray ionization mass spectrometry 显示文摘 | Liu HongXia Gao Lin Liu Mian | 2006 | Microchem J2006，84，12： | 1 |
| 20 | Postoperative impairment of cognitive function in old mice:A possible role for neuroinflammation mediated by HMGB1 ,S100B, and RAGE显示文摘 | Rui -Lin Li Zong-Ze Zhang Mian Peng | 2013 | The Journal of Surgical Research2013，185，2： | 1 |
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