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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | Encapsulating peritoneal sclerosis显示文摘Encapsulating peritoneal sclerosis(EPS) is a debilitating condition characterized by a fibrocollagenous membrane encasing the small intestine, resulting in recurrent small bowel obstructions. EPS is most commonly associated with long-term peritoneal dialysis, though medications, peritoneal infection, and systemic inflammatory disorders have been implicated. Many cases remain idiopathic. Diagnosis is often delayed given the rarity of the disorder combined with non-specific symptoms and laboratory findings. Although cross-sectional imaging with computed tomography of the abdomen can be suggestive of the disorder, many patients undergo exploratory laparotomy for diagnosis. Mortality approaches 50% one year after diagnosis. Treatment for EPS involves treating the underlying condition or eliminating possible inciting agents(i.e. peritoneal dialysis, medications, infections) and nutritional support, frequently with total parenteral nutrition. EPSspecific treatment depends on the disease stage. In the inflammatory stage, corticosteroids are the treatment of choice, while in the fibrotic stage, tamoxifen may be beneficial. In practice, distinguishing between stages may be difficult and both may be used. Surgical intervention, consisting of peritonectomy and enterolysis, is timeconsuming and high-risk and is reserved for situations in which conservative medical therapy fails in institutions with surgical expertise in this area. Herein we review the available literature of the etiology, pathogenesis, diagnosis, and treatment of this rare, but potentially devastating disease. | Christopher J Danford Steven C Lin Martin P Smith Jacqueline L Wolf | 2018 | World Journal of Gastroenterology2018，24，28： | 13 |
| 3 | 曹雪涛院士科研团队论文荣膺中国百篇最具影响国际学术论文--长链非编码RNA1nc-DC通过STAT3调控人DC的分化和功能显示文摘树突状细胞(DC)是免疫系统中重要的抗原提呈细胞,其成熟和功能状态决定着免疫应答的走向和强度。哺乳动物基因组能够转录产生大量的长链非编码RNA(long noncoding RNA,IncRNA),其在免疫系统中的功能还知之甚少。
曹雪涛院十科研团队王品副教授课题组采用了转录组芯片二代测序高通量筛选方法、RNA-pulldown、ChIP-seq等技术展开了对IncRNA在DC分化和功能中作用的研究,发现并鉴定了特异性高表达于DC的1ncRNA,命名为1nc-DC,其可通过抑制STAT3去磷酸化,从而促进DC分化和功能。该研究成果发表于Science杂志[2014,344(6181):310-313],并于2015年12月被评为“中国百篇最具影响国际学术论文”。 | wang p xue y han y lin l wu c xu s jiang z xu j liu q cao x | 2016 | 中国肿瘤生物治疗杂志2016，23，1： | 10 |
| 4 | Effects of anisotropy on time-depth relation in transversely isotropic medium with a vertical axis of symmetry显示文摘It is known that rock anisotropy can significantly influence the phase and energy velocities of an elastic wave,as well as its reflection/transmission(R/T)coefficients.As a result,it can distort the velocity analysis of seismic-reflection data.In this work we present a velocity analysis for seismic-reflection data based on the available anisotropic rock parameters.We analyzed the created errors on time-depth relation of the seismic-reflection data in neglecting rock anisotropy and/or neglecting the difference between energy velocity and phase velocity,including the case of wide-angle reflection.The calculated results show that the effect of rock anisotropy on time-depth relation of seismic-reflection data is dependent not only on the values of anisotropic parameters,but also on the space arrangement of both source and receiver-array.For all studied cases(weak,moderate or strong anisotropy),we found that the effect of rock anisotropy on time-depth relation could not be neglected.Nevertheless,for the case of weak anisotropy,the energy velocity may be replaceable by the phase velocity to obtain a very good approximation on time-depth relation.Consequently,the seismic-reflection data processing algorithm for numerical computations can be simplified. | FA Lin CASTAGNA John P ZENG ZhengWen BROWN Ray L ZHAO MeiShan | 2010 | Chinese Science Bulletin2010，55，21： | 9 |
| 5 | Cerebral aneurysm treatment: modern neurovascular techniques显示文摘Endovascular treatment of cerebral aneurysm continues to evolve with the development of new technologies.This review provides an overview of the recent major innovations in the neurointerventional space in recent years. | Bowen Jiang Michelle Paff Geoffrey P Colby Alexander L Coon Li-Mei Lin | 2016 | Stroke & Vascular Neurology2016，1，3： | 6 |
| 6 | 东方蜜蜂高效的卫生行为机制对于西方蜜蜂抗病育种的启示显示文摘西方蜜蜂(Apismellifera)在世界各地大范围的蜂群损失现象已引起科学界和公众的广泛关注,其健康状况与东方蜜蜂(Apis cerana)相比明显较劣。东方蜜蜂群内可检测到的病原体和寄生虫相对较少,即它们对于生物威胁具有更强的抵抗力,即便是面对异种入侵的新病原(如蜜蜂残翅病毒)。 | Lin Z Page P Li L Qin Y Zhang Y Hu F Neumann P Zheng H Dietemann V 蔺哲广 郑火青 胡福良 | 2016 | 中国蜂业2016，67，12： | 5 |
| 7 | Microporous polymeric composites from bicontinuous microemulsion polymerization using a polymerizable nonionic surfactant 显示文摘 | Gan L M Lin J Poon L P | 1997 | Polymer1997，38，： | 3 |
| 8 | 欧洲和中国的心脏与肾脏远程缺血预适应研究:一项随机对照试验显示文摘远程缺血预适应(remote ischemic preconditioning,RIPC)对经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)术后造影剂肾病(contrast-induced nephropathy,CIN)的潜在保护作用尚待确定。该研究为双盲、随机、安慰剂对照的多中心研究,纳入年龄〈85岁,肾清除率为30~60mL/(min·1.73m^2)的有临床适应证的患者,除了直接PCI外均按1∶1给予RIPC或标准治疗。主要终点是CIN的发生率。次要终点是围手术期心肌梗死(peri-procedural myocardial infarction,PMI)的发生率。 | 刘青 叶鹏 Moretti C Cerrato E Cavallero E Lin S Rossi ML Picchi A Sanguineti F Ugo F Palazzuoli A Bertaina M Presbitero P Shao-Liang C Pozzi R Giammaria M Limbruno U Lefèvre T Gasparetto V Garbo R OmedèP Sheiban I Escaned J Biondi-Zoccai G Gaita F Perl L D'Ascenzo F | 2018 | 中华高血压杂志2018，26，4： | 3 |
| 9 | Procedural complexity independent of P2Y12 reaction unit(PRU)values is associated with acute in situ thrombosis in Pipeline flow diversion of cerebral aneurysms显示文摘background Acute in situ thrombosis is an ischaemic phenomenon during Pipeline embolisation device(PED)procedures with potentially high morbidity and mortality.There is controversy regarding the role of platelet function testing with P2Y12 assay as a predictor of intraprocedural thromboembolic events.There is limited knowledge on whether procedural complexity influences these events.Methods Data were collected retrospectively on 742 consecutive PED cases at a single institution.Patients with intraprocedural acute thrombosis were compared with patients without these events.results A cohort of 37 PED cases with acute in situ thrombosis(mean age 53.8 years,mean aneurysm size 8.4 mm)was matched with a cohort of 705 PED cases without intraprocedural thromboembolic events(mean age 56.4 years,mean aneurysm size 6.9 mm).All patients with in situ thrombosis received intra-arterial and/or intravenous abciximab.The two groups were evenly matched in patient demographics,previous treatment/subarachnoid hemorrhage(SAH)and aneurysm location.There was no statistical difference in postprocedural P2Y12 reaction unit(PRU)values between the two groups,with a mean of 156 in the in situ thrombosis group vs 148 in the control group(p=0.5894).Presence of cervical carotid tortuosity,high cavernous internal carotid artery grade,need for multiple PED and vasospasm were not significantly different between the two groups.The in situ thrombosis group had statistically significant longer fluoroscopy time(60.4 vs 38.4 min,p<0.0001),higher radiation exposure(3476 vs 2160 mGy,p<0.0001),higher rates of adjunctive coiling(24.3% vs 8.37%,p=0.0010)and higher utilisation of balloon angioplasty(37.8% vs 12.2%,p<0.0001).Clinically,the in situ thrombosis cohort had higher incidence of major and minor stroke,intracerebral haemorrhage and length of stay.Conclusions Predictors of procedural complexity(higher radiation exposure,longer fluoroscopy time,adjunctive coiling and need for balloon angioplasty)are associated with acute thrombotic events during PED placement,independent of PRU values. | Bowen Jiang Matthew T Bender Erick M Westbroek Jessica K Campos Li-Mei Lin Risheng Xu Rafael J Tamargo Judy Huang Geoffrey P Colby Alexander L Coon | 2018 | Stroke & Vascular Neurology2018，3，3： | 2 |
| 10 | Molecular films of water-miscible ionic liquids formed on glassy carbon electrodes:characterization and electrochemical applications显示文摘 | Yu P Lin Y Xiang L | 2005 | Langmuir2005，21，： | 1 |
| 11 | A new method for elastic-plastic contact analysis of a deformable sphere and a rigid flat显示文摘 | LIN L P LIN J F | 2006 | ASME Journal ofTribology2006，128，： | 1 |
| 12 | A new experimental approach to evaluate friction in ring test显示文摘 | WANG J P LIN F L HUANG B C | 2008 | Journal of Materials Processing Technology2008，197，13： | 1 |
| 13 | C shaped root canals in mandibular second molars in a Chinese population 显示文摘 | Yang Z P Yang S F Lin Y L | 1988 | Endod Dent Traumatol1988，4，4： | 1 |
| 14 | A near-optimal sensor placement algorithm to achieve complete coverage/discrimination in sensor networks显示文摘 | F Y S Lin P L Chiu | 2005 | IEEE Communications Letters2005，9，1： | 1 |
| 15 | Gender differs: assessing a model of online purchase intentions in e-tail service 显示文摘 | Chiu Y B Lin C P Tang L L | 2005 | Inernational Journal of Service Industry Management2005，16，41： | 1 |
| 16 | Intelligent controlled- wind-turbine emulator and induction-generator system using RBFN显示文摘 | Lin F J Teng L T Shieh P H | 2006 | IEEE Proceedings of Electric Power Applications2006，153，4： | 1 |
| 17 | Extracellular heat shock protein 72 protects schwann cells from hydrogen peroxide-induced apoptosis 显示文摘 | Luo X Tao L Lin P | 2012 | J Neurosci Res2012，90，： | 1 |
| 18 | Application of decolourised hsian-tsao leaf gum to low-fat salad dressing model emulsions: a rheological study显示文摘 | Lai L S Lin P H | 2004 | Journal of the Science of Food and Agriculture2004，84，11： | 1 |
| 19 | Acute myeloid leukemia harboring t(8;21)(q22;q22):a heterogeneous disease with poor outcome in a subset of patients unrelated to secondary cytogenetic aberrations显示文摘 | Lin P Chen L Luthra R | 2008 | Mod Pathol2008，21，8： | 1 |
| 20 | Adaptive Critic Anti-slip Control of Wheeled Autonomous Robot 显示文摘 | Lin W S Chang L H Yang P C | 2007 | IET Control Theory2007，1，1： | 1 |
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