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| 1 | Special Section:SARS-CoV-2 Preliminary evidence from a multicenter prospective observational study of the safety and efficacy of chloroquine for the treatment of COVID-19显示文摘Effective therapies are urgently needed for the SARS-CoV-2 pandemic.Chloroquine has been proved to have antiviral effect against coronavirus in vitro.In this study,we aimed to assess the efficacy and safety of chloroquine with different doses in COVID-19.In this multicenter prospective observational study,we enrolled patients older than 18 years old with confirmed SARS-CoV-2 infection excluding critical cases from 12 hospitals in Guangdong and Hubei Provinces.Eligible patients received chloroquinephosphate s00 mg,orally,once(half dose)or twice(full dose)daily.Patients treated with non-chloroquine therapy were included as historical controls.The primary endpoint is the time to undetectable viral RNA.Secondary outcomes include the proportion of patients with undetectable viral RNA by day 10 and 14,hospitalization time,duration of fever,and adverse events.A total of 197 patients completed chloroquine treatment,and 176patients were included as historical controls.The median time to achieve an undetectable viral RNA was shorter in chloroquine than in non-chloroquine(absolute difference in medians-6.0 days;95%CI-6.0 to—4.0).The duration of fever is shorter in chloroquine(geometric mean ratio 0.6;95%CIO.5 to 0.8).No serious adverse events were observed in the chloroquine group.Patients treated with half dose experienced lower rate of adverse events than with full dose.Although randomized trials are needed for further evaluation,this study provides evidence for safety and efficacy of chloroquine in COVID-19 and suggests that chloroquine can be a cost-effective therapy for combating the COVID-19 pandemic. | Mingxing Huang Man Li Fei Xiao Pengfei Pang Jiabi Liang Tiantian Tang Shaoxuan Liu Binghui Chen Jingxian Shu Yingying You Yang Li Meiwen Tang Jianhui Zhou Guanmin Jiang Jingfen Xiang Wenxin Hong Songmei He Zhaoqin Wang Jianhua Feng Changqing Lin Yinong Ye Zhilong Wu Yaocai Li Bei Zhong Ruilin Sun Zhongsi Hong Jing Liu Huili Chen Xiaohua Wang Zhonghe Li Duanqing Pei Lin Tian Jinyu Xia Shanping Jiang Nanshan Zhong Hong Shan | 2020 | National Science Review2020，7，9： | 20 |
| 2 | Effects of Filler Metal Composition on Inclusions and Inclusion Defects for ER NiCrFe-7 Weldments显示文摘The effects of filler metal(FM) composition on inclusions and inclusion defects for ER NiCrFe-7 weldments have been investigated and analyzed.Results show that as Al,Ti content in FM increases from 0.14 wt%Al,0.30 wt% Ti to 0.42 wt%Al,0.92 wt%Ti,the Al,Ti reduction will increase during welding.Inclusion defects(point-like defects named by welding workers) are prone to form in the high Al,Ti content weldments.Inclusion defects with Mg,Ca,Al,and Ti as major metallic elements have been found on the surface and interior of the weldments,as Al,Ti content in FM is over 0.29 wt%Al,0.62 wt%Ti.Less Ti content in FM cannot prevent ductility-dip-cracking(DDC) through producing enough intragranular precipitates and lessening intergranular M_(23)C_6 precipitates.Nb can be used to replace Ti to reduce the sensitivity of the DDC in the NiCrFe-7 alloy weldments. | Wenlin Mo Shanping Lu Dianzhong Li Yiyi Li | 2013 | Journal of Materials Science & Technology2013，29，5： | 11 |
| 3 | Effects of Boron on the Microstructure,Ductility-dip-cracking,and Tensile Properties for NiCrFe-7 Weld Metal显示文摘The distribution of boron and the microstructure of grain boundary(GB) precipitates(M_(23)(C,B)_6 and M_2B)have been analyzed with their effects on the susceptibility of ductility-dip-cracking(DDC) and tensile properties for NiCrFe-7 weld metal,using optical microscopy(OM),secondary ion mass spectroscopy(SIMS),scanning electron microscopy(SEM),and transmission electron microscopy(TEM).The results show that boron segregates at GBs in NiCrFe-7 weld metal during the welding process.The segregation of boron at GBs promotes the formation of continuous M_(23)(C,B)_6 carbide chains and M_2B borides along GBs.The addition of boron aggravates GB embrittlement and causes more DDC in the weld metal,by its segregation at GBs presenting as an impurity,and promoting the formation of larger and continuous M_(23)(C,B)_6 carbides,and M_2B borides along GBs.DDC in the weld metal deteriorates the ductility and tensile strength of the weld metal simultaneously. | Wenlin Mo Xiaobing Hu Shanping Lu Dianzhong Li Yiyi Li | 2015 | Journal of Materials Science & Technology2015，31，12： | 9 |
| 4 | Time Dependant Weld Shape in Ar-O_2 Shielded Stationary GTA Welding显示文摘静止的煤气的钨弧焊(GTA ) 在 Ar-0.1%O2 下面在 SUS304stainless 钢上被执行, Ar-0.3%02 混合了防护观察熔融的水池的进化并且在焊接形状上调查 Marangoni 传送对流的角色。在焊接以后,在焊接金属的氧内容被使用一个氧 / 氮分析器测量。到氩的氧的小增加基于防护气体能有效地调整焊接水池氧内容。氧作为表面起一个重要作用在在不锈钢焊接水池决定 Marangoni 传送对流的模式的活跃元素。当焊接金属氧内容在临界数值上时, 0.01 wtpct,相应于 Ar-O.3%O2 防护气体混合, Marangoni 传送对流变化从对里面的方向和焊接形状外面戏剧性地从宽浅形状变化深变窄形状。 | Shanping L U Dianzhong LI Hidetoshi Fujii Kiyoshi Nogi | 2007 | Journal of Materials Science & Technology2007，23，5： | 5 |
| 5 | Protective effects of taurine against muscle damage induced by diquat in 35 days weaned piglets显示文摘Background: Oxidative stress is a key factor that influences piglets' health. Taurine plays an imperative role in keeping the biological system from damage. This study was conducted to investigate the protective effect of taurine against muscle injury due to the secondary effect of diquat toxicity.Results: Our study found that taurine effectively and dose-dependently alleviated the diquat toxicity induced rise of feed/gain, with a concurrent improvement of carcass lean percentage. The plasma content of taurine was considerably increased in a dose-dependent manner. Consequently, dietary taurine efficiently improved the activity of plasma antioxidant enzymes. Furthermore, taurine attenuated muscle damage by restoring mitochondrial micromorphology, suppressing protein degradation and reducing the percentage of apoptotic cells in the skeletal muscle. Taurine supplementation also suppressed the genes expression levels of the antioxidant-, mitochondrial biogenesis-, and muscle atrophy-related genes in the skeletal muscle of piglets with oxidative stress.Conclusions: These results showed that the dose of 0.60% taurine supplementation in the diet could attenuate skeletal muscle injury induced by diquat toxicity. It is suggested that taurine could be a potential nutritional intervention strategy to improve growth performance. | Chaoyue Wen Fengna Li Qiuping Guo Lingyu Zhang Yehui Duan Wenlong Wang Jianzhong Li Shanping He Wen Chen Yulong Yin | 2020 | Journal of Animal Science and Biotechnology2020，11，4： | 5 |
| 6 | Effect of Structural Parameters of Double Shielded TIG Torch on the Fusion Zone Profile for 0Cr13Ni5Mo Martensitic Stainless Steel显示文摘The effects of double shielded TIG(tungsten inert gas)torch’s structural parameters,including the flow rate ratio between the inner and outer layers of gas and the extended length of the electrode(abbreviated as ELE in this work),on the fusion zone profile have been investigated for 0Cr13Ni5Mo martensitic stainless steel.Results show that the double shielded TIG process yields relatively high penetration of the weld pool in a broad range of the structural parameters.ELE over 3 mm is too large and causes adverse reactions on the protection of electrode.The outer gas with relatively high flow rate or the outer layer with high oxygen content is conducive to the oxygen dissolved into the arc,which results in the oxidation of the weld pool surface and the electrode tip.The double shielded TIG welded metal was tested and presented good impact property. | Dongjie Li Shanping Lu Dianzhong Li Yiyi Li | 2014 | Journal of Materials Science & Technology2014，30，9： | 4 |
| 7 | Removal of phosphate by Fe-coordinated amino-functionalized 3D mesoporous silicates hybrid materials显示文摘Phosphate removal from aqueous waste streams is an important approach to control the eutrophication downstream bodies of water.A Fe(III) coordinated amino-functionalized silicate adsorbent for phosphate adsorption was synthesized by a post-grafting and metal cation incorporation process.The surface structure of the adsorbent was characterized by X-ray diffraction,N2 adsoropion/desoprotion technique,and Fourier transform infrared spectroscopy.The experimental results showed that the adsorption equilibrium data were well fitted to the Langmuir equation.The maximum adsorption capacity of the modified silicate material was 51.8 mg/g.The kinetic data from the adsorption of phosphate were fitted to pseudo second-order model.The phosphate adsorption was highly pH dependent and the relatively high removal of phosphate fell within the pH range 3.0-6.0.The coexistence of other anions in solutions has an adverse effect on phosphate adsorption;a decrease in adsorption capacity followed the order of exogenous anions:F > SO2-4 > NO-3 > Cl-.In addition,the adsorbed phosphate could be desorbed by NaOH solutions.This silicate adsorbent with a large adsorption capacity and relatively high selectivity could be utilized for the removal of phosphate from aqueous waste streams or in aquatic environment. | Jianda Zhang Zhemin Shen Zhijian Mei Shanping Li Wenhua Wang | 2011 | Journal of Environmental Sciences2011，23，2： | 4 |
| 8 | Effect of aging treatment on the microstructures and mechanical properties evolution of 25Cr-20Ni austenitic stainless steel weldments with different Nb contents显示文摘The microstructure evolutions and the mechanical properties of the 25Cr-20Ni austenitic stainless steel weld metals with different Nb contents were investigated during the long term aging treatment at 700~?C.M_(23)C_6,Nb(C,N),α-Cr phase and Nb-nitride phase(Z phase)were observed in the microstructures of the aged weld metals.The results showed that theα-Cr phase precipitated in the interdendritic regions of the weld metals after being exposed to~ 700?C for 500 h and the element Nb accelerated the precipitation of theα-Cr phase significantly.The density of theα-Cr phase decreased with the increase of the distance away from the primary Nb(C,N).Additionally,theα-Cr phase showed a crystallographic relationship with the austenitic matrix,■.It was observed that the Z phase precipitated in the periphery of the Nb(C,N)and may replace the Nb(C,N)after long term exposure to high temperature.The transformation of the Nb(C,N)into Z phase suggested that the Z phase had a higher stability than the Nb(C,N)par^ticles at 700?C for long term aging.The tensile strength of the Nb-bearing weld metal showed a continuous decrease at the initial stage of the aging treatment and then went up slightly with the prolonged aging time.However,the elongations and the impact energies of the weld metals decreased monotonously with the increase of the aging time. | Xu Zhang Dianzhong Li Yiyi Li Shanping Lu | 2019 | Journal of Materials Science & Technology2019，35，4： | 3 |
| 9 | Principles Giving High Penetration under the Double Shielded TIG Process显示文摘A new welding method named double shielded tungsten inert gas(TIG) has been developed to improve the TIG weld penetration.The main principles to increase the weld depth have been discussed.Results show that the critical oxygen content in the weld pool is around 100 × 10^(-6) as the temperature coefficient of surface tension changes from negative to positive.The tracer test using pure silver shows that the direction of Marangoni convection changes as the oxygen content increases in the weld pool.The effect of arc constriction on the weld depth has been evaluated on a water-cooled copper plate,and the result indicates that the torch of double shielded can give a more powerful arc.Heavy oxide on the pool surface has undesirable impacts on the increasing of weld depth as the oxygen excessively accumulates in weld pool.It is possible to form chromium oxide in the weld process,while the iron oxide may form as the weld surface exposes to the air after the shielded gas moving away. | Dongjie Li Shanping Lu Dianzhong Li Yiyi Li | 2014 | Journal of Materials Science & Technology2014，30，2： | 3 |
| 10 | Recognition of cotton growth period for precise spraying based on convolution neural network显示文摘Dynamic acquisition of crop morphology is beneficial to real-time variable decision of precise spraying operations in fields.However,the existing spraying quantity regulation has high tolerance on the statistical characteristics of regional morphology,so expensive LiDAR and ultrasonic radar can’t make full use of their high accuracy,and can reduce decision speed because of too much detail of branches and leaves.Therefore,designing a novel recognition system embedded machine learning with low-cost monocular vision is more feasible,especially in China,where the agricultural implements are medium sizes and cost-sensitive.In addition,we found that the growth period of crops is an important reference index for guiding spraying.So,taking cotton as a case study,a cotton morphology acquisition by a single camera is established,and a cotton growth period recognition algorithm based on Convolution Neural Network(CNN)is proposed in this paper.Through the optimization process based on confusion matrix and recognition efficiency,an optimized CNN model structure is determined from 9 different model structures,and its reliability was verified by changing training sets and test sets many times based on the idea of kfold test.The accuracy,precision,recall,F1-score and recognition speed of this CNN model are 93.27%,95.39%,94.31%,94.76%and 71.46 ms per image,respectively.In addition,compared with the performance of VGG16 and AlexNet,the convolution neural network model proposed in this paper has better performance.Finally,in order to verify the reliability of the designed recognition system and the feasibility of the spray decision-making algorithm based on CNN,spraying deposition experiments were carried out with 3 different growthperiods of cotton.The experiments’results validate that after the optimal spray parameters were applied at different growth periods respectively,the average optimum index in 3 growth periods was 42.29%,which was increased up to 62.24%than the operations without distinguishing growth periods. | Shanping Wang Yang Li Jin Yuan Laiqi Song Xinghua Liu Xuemei Liu | 2021 | Information Processing in Agriculture2021，8，2： | 2 |
| 11 | Microstructural evolution and stress relaxation cracking mechanism for Super304H austenitic stainless steel weld metal显示文摘The pre-compressed CT technique was used to quantitatively investigate the formation of stress relaxation cracks under different tensile residual stresses and aging time in Super304H austenitic stainless steel weld metal.The statistical results revealed that intergranular cracks could occur within 2000 h under 650℃ when the residual stress was applied with greater than 18 KN pre-compression force.Detailed grain interior and boundary analyses showed that the growth of intragranular Cu-rich particles could induce a strong grain interior,and the intergranular Nb(C,N)carbides were one of the causes to crack under short-term aging time.For long-term aging time conditions,the intergranular M_(23)C_(6)carbides were more susceptible to crack than intergranular Nb(C,N)carbides.Finally,the mechanism responsible for stress relaxation cracking formation was carefully illustrated for the weld metals after short-term aging and long-term aging,respectively. | Xiaopeng Xiao Dianzhong Li Yiyi Li Shanping Lu | 2022 | Journal of Materials Science & Technology2022，，5： | 2 |
| 12 | Perfor- mance of blast furnace dust clay sodium silicate ceramic particles (BCSCP) for brewery wastewater treatment in a biological aerated filter显示文摘 | Li Shanping Cui Jiangjie Zhang Qilei | 2010 | Desalination2010，258，123： | 1 |
| 13 | Effect of aeration rate on the emission of N 2 O in anoxic–aerobic sequencing batch reactors (A/O SBRs)显示文摘 | Zhen Hu Jian Zhang Shanping Li Huijun Xie Jinhe Wang Tingting Zhang Yiran Li Huayong Zhang | 2009 | Journal of Bioscience and Bioengineering2009，，5： | 1 |
| 14 | The Highest Dam in the World under Construction: The Shuangjiangkou Core-Wall Rockfill Dam显示文摘沙漠化是指土地的退化[1–4]。作为一个严重的全球性环境问题,沙漠化已经引起了国际社会的广泛关注。1994年,联合国通过了《联合国防治荒漠化公约》[4]。从那时起,世界各国在防治沙漠化方面做出了不懈的努力[5–12]。然而,沙漠化的蔓延并没有得到有效的控制,情况甚至变得更糟:它正在以每年50 000~70 000 | Shanping Li Bin Duan | 2016 | Engineering2016，2，3： | 1 |
| 15 | Effeet of aeration rate on the emission of Nz O in anoxic-aerobic sequencing batch reactors (A/O SBRs)显示文摘 | HU Zhen ZHANG Jian LI Shanping | 2010 | Journal of Bioscience and Bioengi- neering2010，109，5： | 1 |
| 16 | Effect of aeration rate on the emission of N2O in anoxic-aerobic sequencing batch reactors (A/O SBRs) 显示文摘 | Zhen Hu Jian Zhang Shanping Li | 2010 | Journal of Bioscience and Bioengineering2010，109，5： | 1 |
| 17 | Minimization of nitrous oxide emission from anoxiceoxic biological nitrogen removal process: Effect of influent COD/NH4+ ratio and feeding strategy 显示文摘 | Zhen Hu Jian Zhang Huijun Xie Shuang Liang and Shanping Li | 2013 | Journal of Bioscience and Bioengineering2013，115，3： | 1 |
| 18 | Effects of Ti-bearing inclusions on the microstructure and mechanical properties of MAG multilayer weld metal显示文摘The metal active gas (MAG) multilayer weld metal consists of the columnar grain zone (CGZ) and the fine grain zone (FGZ). Mechanical properties and microstructure of the CGZ and FGZ have been analyzed and evaluated. The inclusion with a size of 0.2-1.0 μm is typical log-normal distribution. The morphology of inclusions has been analyzed using transmission electron microscope (TEM). With the microalloying element Ti addition, much MnTiO3 phase precipitates on the Mn-silicates matrix, which is beneficial for the nucleation of acicular ferrite (AF). The probable mechanism for the nucleation of AF has been discussed. | Xin WANG Wenchao DONG Shanping LU Guangzhong HE Xu ZHAO Dianmai ZHOU Yiyi LI | 2012 | Acta Metallurgica Sinica(English Letters)2012，25，1： | 1 |
| 19 | Treating COVID-19 with Chloroquine显示文摘A novel coronavirus disease 2019(COVID-19)emerged around December 2019 in Wuhan,China and has spread rapidly worldwide(Lu et al.,2020).Until March 27,2020,the Chinese health authorities had reported 82082 confirmed COVID-19 cases in China with 3298 deaths and 381443 confirmed cases with 20787 deaths outside China.The World Health Organization(WHO)named the virus SARS-CoV-2,which belongs to a distinct clade from the human severe acute respiratory syndrome CoV(SARS-CoV)and Middle East respiratory syndrome CoV(MERSCoV)(Zhu et al.,2020). | Mingxing Huang Tiantian Tang Pengfei Pang Man Li Ruolan Ma Jiahui Lu Jingxian Shu Yingying You Binghui Chen Jiabi Liang Zhongsi Hong Huili Chen Ling Kong Dajiang Qin Duanqing Pei Jinyu Xia Shanping jiang Hong Shan | 2020 | Journal of Molecular Cell Biology2020，12，4： | 1 |
| 20 | Microstructure and Mechanical Properties of Simulated Heat-affected Zones of EP-823 Steel for ADS/LFR显示文摘EP-823 steel is one of the candidate materials for accelerator-driven systems/lead-cooled fast reactors(ADS/LFR).Its weldability was investigated by mechanical property tests and microstructure analysis on the enlarged heat-affected zones(HAZs) made by numerical and physical simulation.The finite element numerical simulation could simulate the welding thermal cycle of the characteristic regions in HAZs with extremely high accuracy.The physical simulation performed on a Gleeble simulator could enlarge the characteristic regions to easily investigate the relationship between the microstructure evolution and the mechanical properties of the HAZs.The results showed that the simulated partially normalized zone comprising tempered martensite,newly formed martensite and more tiny carbides has the highest impact energy.The fully normalized zone exhibits the highest hardness because of the quenched martensite and large carbides.The ductile property of the overheated zone is poor for the residual deltaferrite phases and the quenched martensite. | Shanping Lu Tian Liang Yongkui Li Dianzhong Li Lijian Rong Yiyi Li | 2015 | Journal of Materials Science & Technology2015，31，8： | 1 |
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