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| 1 | Is autoimmune hepatitis a frequent finding among HCV patients with intense interface hepatitis?显示文摘AIM:To evaluate the overlap of autoimmune hepatitis in hepatitis C virus(HCV)-infected patients with intense interface hepatitis.METHODS:Among 1759 patients with hepatitis C submitted to liver biopsy,92(5.2%) presented intense interface hepatitis.These patients were evaluated regarding the presence of antinuclear antibody(ANA),anti-smooth muscle antibody(SMA) and anti-liver/kidney microsomal antibody(LKM-1),levels of γ-globulin and histological findings related to autoimmune hepatitis(plasma cell infiltrate and presence of rosettes).RESULTS:Among patients with hepatitis C and intense interface hepatitis there was a low prevalence of autoantibodies(ANA=12%,SMA=5%,LKM-1=0%) and the median γ-globulin level was within the normal range.Typical histological findings of autoimmune disease were observed in only two cases(2%).After applying the score for diagnosis of autoimmune hepatitis,only one patient was classified with a definitive diagnosis of autoimmune hepatitis.Since overlap with autoimmune hepatitis was not the explanation for the intense necroinflammatory activity in patients with chronic hepatitis C we sought to identify the variables associated with this finding.The presence of intense interface hepatitis was associated with more advanced age,both at the time of infection and at the time of the biopsy,and higher prevalence of blood transfusion and alcohol abuse.CONCLUSION:Although possible,overlap with autoimmune hepatitis is a very rare association in HCV-infected patients with intense interface hepatitis,an unusual presentation which seems to be related to other host variables. | Rosilene G Badiani Vitória Becker Renata M Perez Carla AL Matos Lara B Lemos Valéria P Lanzoni Luis Eduardo C Andrade Alessandra Dellavance Antonio Eduardo B Silva Maria Lucia G Ferraz | 2010 | World Journal of Gastroenterology2010，16，29： | 7 |
| 2 | Advances in enhanced biological phosphorus removal: from micro to macro scale 显示文摘 | OEHMEN A LEMOS P C CARVALHO G | 2007 | Water Research2007，41，11： | 1 |
| 3 | Advances in enhanced biological phosphorus removal:from micro to macro scale显示文摘 | Oehmen A Lemos P C Carvalho G | 2007 | Water Research2007，41，11： | 1 |
| 4 | Advances in enhanced biological phosphorus removal:from micro to macro scale显示文摘 | Oehmen A Lemos P C Carvalho G Yuan Z Kelley J Blackall L L Reis M A M | 2007 | Water Research2007，41，11： | 1 |
| 5 | Elective sirolimus-eluting stent implantation for left main coronary artery disease:six-month angiographic follow-up and 1-year clinical outcome 显示文摘 | ARAMPATZIS C A LEMOS P A HOYE A | 2004 | Catheter Cardiovasc Interv2004，62，3： | 1 |
| 6 | Characterization of specific antibodies against cytomegalovirus(CMV)-encoded interleukin 10 produced by 28%of CMV seropositive blood donors显示文摘 | de Lemos Rieper C Galle P Pedersen B K | 2011 | Journal of Gene Virology2011，92，7： | 1 |
| 7 | Advances in enhanced biological phosphorus removal: from micro to macro scale 显示文摘 | Oehmen A Lemos P C Carvalho G | 2007 | Water Res2007，41，11： | 1 |
| 8 | Phylogeography of the endangered rosewood Dalbergia nigra (Fabaceae): insights into the evolutionary history and conservation of the Brazilian Atlantic Forest显示文摘 | Ribeiro R A Lemos J P Ramos A C S | 2011 | Heredity2011，106，： | 1 |
| 9 | Crude glycerol as feedstock forpolyhydroxyalkanoates production by mixed microbial cultures显示文摘 | Moita R Freches A Lemos P C | 2014 | Water Research2014，58，： | 1 |
| 10 | A faulttolerant architectural approach for dependable systems显示文摘 | de Lemos R de Castro P A G Rubira C M | 2006 | IEEE Software2006，23，2： | 1 |
| 11 | Advances in enhanced biological phosphorus removal:from micro to macro scale 显示文摘 | OEHMEN A LEMOS P C CARVALHO G | 2007 | Water Res2007，41，11： | 1 |
| 12 | Microbial charac- terisation of polyhydroxyalkanoates storing populations se- lected under different operating conditions using a cell-sor- ting RT-PCR approach显示文摘 | Lemos P C Levantesi C Serafim L S | 2008 | Applied Microbiology and Bi- otechnology2008，78，： | 1 |
| 13 | A fault-tolerant architectural approach for dependable system 显示文摘 | LEMOS R D GUERRA P A RUBIRA C M F | 2006 | IEEE Software2006，23，2： | 1 |
| 14 | Model for carbon metabolism in biological phosphorus removal processes based on in vivo 13C-NMR labelling experiments显示文摘 | Pereira H Lemos P C Reis M A | 1996 | Water Res1996，30，9： | 1 |
| 15 | Elucidation of metabolic pathways of glycogen accumulating organisms with in vivo ^13C nuclear magnetic resonance显示文摘 | LEMOS P C DAI Y YUAN Z | 2008 | Environmental Microbiology2008，9，11： | 1 |
| 16 | Effect of hydrogen sulfide on growth of sulfate reducing bacteria 显示文摘 | Reis M A M Almeida J S Lemos P C | 1992 | Biotechnology and Bioengineering1992，40，5： | 1 |
| 17 | Advances in enhanced biological phosphorus removal:from micro to macro scale显示文摘 | Oehmen A Lemos P C Carvalho G | | 0，，11： | 1 |
| 18 | Optimization of polyhydroxybutyrate production by mixed cultures submitted to aerobic dynamic feeding conditions 显示文摘 | Serafim L S Lemos P C Oliveira R | 2004 | Biotechnol Bioeng2004，87，2： | 1 |
| 19 | Advanced in enhanced biological phosphorus removal from micro to macro scale显示文摘 | Oehmen A Lemos P C Carvalho G | 2007 | Water Research2007，41，： | 1 |
| 20 | Recent advances in polyhydroxyalkanoate production by mixed aerobic cultures: From the substrate to the final product 显示文摘 | Dias J M L Lemos P C Serafim L S | 2006 | Macromol Biosci2006，6，11： | 1 |
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