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| 1 | Is autoimmune hepatitis a frequent finding among HCV patients with intense interface hepatitis?显示文摘AIM:To evaluate the overlap of autoimmune hepatitis in hepatitis C virus(HCV)-infected patients with intense interface hepatitis.METHODS:Among 1759 patients with hepatitis C submitted to liver biopsy,92(5.2%) presented intense interface hepatitis.These patients were evaluated regarding the presence of antinuclear antibody(ANA),anti-smooth muscle antibody(SMA) and anti-liver/kidney microsomal antibody(LKM-1),levels of γ-globulin and histological findings related to autoimmune hepatitis(plasma cell infiltrate and presence of rosettes).RESULTS:Among patients with hepatitis C and intense interface hepatitis there was a low prevalence of autoantibodies(ANA=12%,SMA=5%,LKM-1=0%) and the median γ-globulin level was within the normal range.Typical histological findings of autoimmune disease were observed in only two cases(2%).After applying the score for diagnosis of autoimmune hepatitis,only one patient was classified with a definitive diagnosis of autoimmune hepatitis.Since overlap with autoimmune hepatitis was not the explanation for the intense necroinflammatory activity in patients with chronic hepatitis C we sought to identify the variables associated with this finding.The presence of intense interface hepatitis was associated with more advanced age,both at the time of infection and at the time of the biopsy,and higher prevalence of blood transfusion and alcohol abuse.CONCLUSION:Although possible,overlap with autoimmune hepatitis is a very rare association in HCV-infected patients with intense interface hepatitis,an unusual presentation which seems to be related to other host variables. | Rosilene G Badiani Vitória Becker Renata M Perez Carla AL Matos Lara B Lemos Valéria P Lanzoni Luis Eduardo C Andrade Alessandra Dellavance Antonio Eduardo B Silva Maria Lucia G Ferraz | 2010 | World Journal of Gastroenterology2010，16，29： | 7 |
| 2 | Combination therapy with Abciximab reduces angiographically evident thrombus in acute myocardial infarction: A TIMI 14 substudy显示文摘 | Gibson C M de Lemos J A Murphy S A | 2001 | Circulation2001，103，21： | 1 |
| 3 | Combination therapy with abciximab reduces an giographieally evident thrombus in acute myocardial infarc tion: aTIMI 14 substudy显示文摘 | GIBSON C M DE LEMOS J A MURPHY S A | 2001 | Circulation2001，103，21： | 1 |
| 4 | Advances in enhanced biological phosphorus removal:from micro to macro scale显示文摘 | Oehmen A Lemos P C Carvalho G Yuan Z Kelley J Blackall L L Reis M A M | 2007 | Water Research2007，41，11： | 1 |
| 5 | Content and traffic of taurine in hippocampal reactive astrocytes显示文摘 | Junyent F De Lemos L Utrera J Paco S Aguado F Camins A Pallds M Romero R Auladell C | 2011 | Hippocampus2011，21，2： | 1 |
| 6 | Synthesis of polyhydroxyalkanoates from different short-chain fatty acids by mixed cultures submitted to aerobic dynamic feeding显示文摘 | Paulo C Lemos Lu'isa S S Maria A M R | 2006 | Journal of Biotechnology2006，122，： | 1 |
| 7 | A faulttolerant architectural approach for dependable systems显示文摘 | de Lemos R de Castro P A G Rubira C M | 2006 | IEEE Software2006，23，2： | 1 |
| 8 | Influence of pH and high pressure on the thermal inactivation kinetics of horseradish peroxidase显示文摘 | Lemos M A Oliveria J C Anne van Loey | 1999 | Food Biotechnology1999，13，1： | 1 |
| 9 | A fault-tolerant architectural approach for dependable system 显示文摘 | LEMOS R D GUERRA P A RUBIRA C M F | 2006 | IEEE Software2006，23，2： | 1 |
| 10 | Model for carbon metabolism in biological phosphorus removal processes based on in vivo 13C-NMR labelling experiments显示文摘 | Pereira H Lemos P C Reis M A | 1996 | Water Res1996，30，9： | 1 |
| 11 | Effect of hydrogen sulfide on growth of sulfate reducing bacteria 显示文摘 | Reis M A M Almeida J S Lemos P C | 1992 | Biotechnology and Bioengineering1992，40，5： | 1 |
| 12 | An online systerm for preconcentration and determination of lead in wine samples by FAAS显示文摘 | Lemos V A Guardrdia M De La Ferreira S L C | 2002 | Talanta2002，58，3： | 1 |
| 13 | Recent advances in polyhydroxyalkanoate production by mixed aerobic cultures: From the substrate to the final product 显示文摘 | Dias J M L Lemos P C Serafim L S | 2006 | Macromol Biosci2006，6，11： | 1 |
| 14 | Synthesis of polyhydroxyalkanoates from different short-chain fatty acids by mixed cultures submitted to aerobic dynamic feeding 显示文摘 | Paulo C Lemos Luisa S Serafim Maria A M Reis | 2006 | Journal of Biotechnology2006，122，： | 1 |
| 15 | Recent advances in polyhydroxyalkanoate production by mixed aer obic cultures: from the substrate to the final product显示文摘 | DIAS J M L LEMOS P C SERAFIM L S | 2006 | Macromolecular Bioscience2006，6，11： | 1 |
| 16 | Influence of pH and high pressure on the thermal inactivation kinetics of horseradish peroxidase显示文摘 | Lemos M A Oliveria J C Anne van Loey | 1999 | Food Biotechnology1999，13，1： | 1 |
| 17 | Primary follicular car- cinoma arising in ectopic thyroid tissue of the lateral neck: a case reportl 显示文摘 | Subramony C Baliga M Lemos LB | 2010 | J Korean Soc Radiol2010，63，5： | 1 |
| 18 | Evaluation of the bioremoval of Cr (VI) and TOC in biofilters under continuous operation using response surface methodology 显示文摘 | Leles D M Lemos D A Filho U C | 2012 | Biodegradation2012，23，44： | 1 |
| 19 | Association between Natriuretic Peptides and Mortality among Patients Admitted with Myocardial Infarction:A Report from the ACTION Registry-GWTG(TM)显示文摘 | Scirica Benjamin M Kadakia Mitul B de Lemos James A Roe Matthew T Morrow David A Li Shuang Wiviott Stephen D Kontos Michael C | 2013 | Clinical Chemistry2013，59，8： | 1 |
| 20 | Early noninvasive detection of failed epicardial reperfusion after fibrinolytic therapy 显示文摘 | De Lemos J A Morrow D A Gibson C M | 2001 | Am J Cardiol2001，88，： | 1 |
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