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| 1 | Nat Genet:单细胞分析解开结直肠癌细胞的神秘面纱显示文摘结合单细胞基因组学和计算机技术,一个研究团队(包括来自杰克逊实验室(JAx)单细胞生物学主任Paul Robson博士在内)鉴定出了11种结直肠癌肿瘤的癌细胞组成及邻近的非癌细胞。这对于更好的肿瘤靶向诊断和治疗很重要。”使用单细胞测序。”JAX科学家、这篇发表在Nature Genetics上的文章共同第一作者Elise Courtois说道。”我们可以根据肿瘤中的细胞组成将结直肠癌进一步分类。因为每种亚型的肿瘤病人生存率存在差别,我们的方法将为肿瘤医生提供更多的关于肿瘤预后和治疗的信息。” | Huipeng Li, Elise T Courtois, Debarka Sengupta, Yuliana Tan Shyam Prabhakar Elise T Courtois, Yuliana Tan Paul Robson Debarka Sengupta Kok Hao Chen, Jolene Jie Lin Goh Paul Jongjoon Choi Say Li Kong, Axel M Hillmer Iain Beehuat Tan Clarinda Chua Iain Beehuat Tan Lim Kiat Hon Wah Siew Tan Mark Wong Lawrence J K Wee Iain Beehuat Tan Paul Robson Paul Robson Paul Robson | 2017 | 现代生物医学进展2017，17，15： | 37 |
| 2 | Efficacy and safety of canagliflozin versus glimepiride in patients with type 2 diabetes inadequately controlled with metformin (CANTATA-SU): 52 week results from a randomised, double-blind, phase 3 non-inferiority trial显示文摘 | William T Cefalu Lawrence A Leiter Kun-Ho Yoon Pablo Arias Leo Niskanen John Xie Dainius A Balis William Canovatchel Gary Meininger | 2013 | The Lancet2013，，： | 3 |
| 3 | The Use of Negative-Pressure Wound Therapy (NPWT) in the Temporary Treatment of Soft-Tissue Injuries Associated With High-Energy Open Tibial Shaft Fractures显示文摘 | Barnaby T Dedmond Bill Kortesis Kathleen Punger Jordan Simpson Joseph Argenta Brenda Kulp Michael Morykwas Lawrence X Webb | 2007 | Journal of Orthopaedic Trauma2007，，1： | 2 |
| 4 | Concepts of blood transfusion in adults显示文摘 | Lawrence T Goodnough Jerrold H Levy Michael F Murphy | 2013 | The Lancet2013，，9880： | 2 |
| 5 | Relationships between soil properties and vegetation at the Northern Experimental Forest, Howland, Maine显示文摘 | LEVINE L R KNOX R G AND LAWRENCE W T | 1994 | Remote Sensing of Environment1994，47，： | 1 |
| 6 | The polities of organizational learning:Integrating power into the 41 framework显示文摘 | Lawrence T B Mauws M K Dyck B | 2005 | Academy of Management Review2005，30，1： | 1 |
| 7 | CT angiography in acute ischemic stroke:preliminary results显示文摘 | Piero V Lawrence N T Neil M B | 2002 | Stroke2002，33，： | 1 |
| 8 | Fluid flow along a channel with an asymmetric oscillating constriction显示文摘 | Stephanoff K D Pedley T J Lawrence C J Secomb T W | 1983 | Nature1983，305，20： | 1 |
| 9 | The use of 3-Ddose volume analysis to predict radiation hepatitis显示文摘 | Lawrence T S Ten Haken R K Kessler M L | 1992 | Int J Radiat Oncol Biol Phys1992，23，9： | 1 |
| 10 | Mechanisms for the Cytotoxicity of eysteamine显示文摘 | Jeitner T M Lawrence D A | 2001 | Toxicological Sciences2001，63，1： | 1 |
| 11 | The application of a piezoelectric bar gauge to shock tube studies显示文摘 | Edwards D H Davies L Lawrence T R | 1964 | J Sci Instrum1964，64，： | 1 |
| 12 | Observation on the decline in sperm quality of Penaeus serilferus under laboratory conditions 显示文摘 | Leung T J R Lawrence A L | 1987 | Aquaculture1987，65，： | 1 |
| 13 | Nonlinear dimensionalityreduction by locally linear embedding 显示文摘 | Sam T R Lawrence K S | 2000 | Science2000，290，22： | 1 |
| 14 | Review of genes and linkage groups in cucumber显示文摘 | Lawrence K P Wehner T C | 1990 | HortScience1990，25，6： | 1 |
| 15 | Lowering the prophylactic platelet transfusion threshold:apropective analysis显示文摘 | Lawrence JB Yomtovian RA Hammons T | 2001 | Leuk Lymphoma2001，41，： | 1 |
| 16 | Nonlinear dimensionality reduction by locally linear embedding显示文摘 | Sam T R Lawrence K S | 2000 | Science2000，290，5000： | 1 |
| 17 | Toxic moieties in ruminal and duodenal digesta and in milk, and hepatic integrity in cattle given diets based on rapeseed meals of different glucosinolate con tents either untreated or treated with heat or formaldehyde显示文摘 | Subuh A M H Rowa T G Lawrence T L J | 1995 | Animal Feed Science and Technology1995，52，： | 1 |
| 18 | Radiosensitization by gemcitabine显示文摘 | Lawrence T S Eisbruch A McGun C J | 1999 | Oncology(Wiiliston Park)1999，13，105： | 1 |
| 19 | Institutional Strategy 显示文摘 | Lawrence T B | 1999 | Joumal of Management1999，25，2： | 1 |
| 20 | Overholt surgical mangement of cervical soft disc herniation:a comparison between the anterior and posterior approach显示文摘 | Harry N Herkowotz Lawrence T | 1990 | Spine1990，15，10： | 1 |
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