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| 1 | Endoscopicultrasonographyforsurveillanceofindividualsathighriskfor pancreaticcancer显示文摘Pancreatic cancer is a highly lethal disease with a ge-netic susceptibility and familial aggregation found in 3%-16% of patients. Early diagnosis remains the only hope for curative treatment and improvement of prog-nosis. This can be reached by the implementation of an intensive screening program, actually recommended for individuals at high-risk for pancreatic cancer de-velopment. The aim of this strategy is to identify pre-malignant precursors or asymptomatic pancreatic can-cer lesions, curable by surgery. Endoscopic ultrasound (EUS) with or without fine needle aspiration(FNA) seems to be the most promising technique for early de-tection of pancreatic cancer. It has been described as a highly sensitive and accurate tool, especially for small and cystic lesions. Pancreatic intraepithelial neoplasia, a precursor lesion which is highly represented in high-risk individuals, seems to have characteristics chronic pancreatitis-like changes well detected by EUS. Many screening protocols have demonstrated high diagnostic yields for pancreatic pre-malignant lesions, allowing prophylactic pancreatectomies. However, it shows a high interobserver variety even among experienced en-dosonographers and a low sensitivity in case of chronic pancreatitis. Some new techniques such as contrast-en-hanced harmonic EUS, computer-aided diagnostic tech-niques, confocal laser endomicroscopy miniprobe andthe detection of DNA abnormalities or protein markersby FNA, promise improvement of the diagnostic yield ofEUS. As the resolution of imaging improves and as ourknowledge of precursor lesions grows, we believe thatEUS could become the most suitable method to detectcurable pancreatic neoplasms in correctly identifiedasymptomatic at-risk patients. | Lami G Biagini MR Galli A | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，7： | 8 |
| 2 | Trabecular Bone Score: A Noninvasive Analytical Method Based Upon the DXA Image显示文摘 | Barbara C Silva William D Leslie Heinrich Resch Olivier Lamy Olga Lesnyak Neil Binkley Eugene V McCloskey John A Kanis John P Bilezikian | 2014 | J Bone Miner Res2014，，3： | 2 |
| 3 | Performance of American Society for Gastrointestinal Endoscopy guidelines for dyspepsia in Saudi population: Prospective observational study显示文摘AIM: To evaluate adherence of primary care physicians(PCPs) to international guidelines when referring patients for upper-gastrointestinal endoscopy(UGE), evaluate the importance of alarm symptoms and the performance of the American Society for Gastrointestinal Endoscopy(ASGE) guidelines in a Saudi population.METHODS: A prospective, observational cross-sectional study on dyspeptic patients undergoing UGE who were referred by PCPs over a 4 mo period. Refer-rals were classified as appropriate or inappropriate according to adherence to ASGE guidelines.RESULTS: Total of 221 dyspeptic patients was enrolled; 161 patients met our inclusion criteria. Mean age was 40.3 years(SD ± 18.1). Females comprised 70.1%. Alarm symptoms included low hemoglobin level(39%), weight loss(18%), vomiting(16%), loss of appetite(16%), difficulty swallowing(3%), and gastrointestinal bleeding(3%). Abnormal endoscopy findings included gastritis(52%), duodenitis(10%), hiatus hernia(7.8%), features suggestive of celiac disease(6.5%), ulcers(3.9%), malignancy(2.6%) and gastroesophageal reflux disease(GERD: 17%). Among patients who underwent UGE, 63% met ASGE guidelines, and 50% had abnormal endoscopic findings. Endoscopy was not indicated in remaining 37% of patients. Among the latter group, endoscopy was normal in 54% of patients. There was no difference in proportion of abnormal endoscopic findings between two groups(P = 0.639).CONCLUSION: Dyspeptic patients had a low prevalence of important endoscopic lesions, and none of the alarm symptoms could significantly predict abnormalendoscopic findings. | Nahla A Azzam Majid A Almadi Hessah Hamad Alamar Lamis Atyah Almalki Rehab Nawaf Alrashedi Rawabi Saleh Alghamdi Waleed Al-hamoudi | 2015 | World Journal of Gastroenterology2015，21，2： | 2 |
| 4 | PIK3CA in breast carcinoma : a mutational analysis of sporadic and hereditary cases 显示文摘 | Michelucei A Di Cristofano C Lami A | 2009 | Diagn Mol Pathol2009，18，4： | 1 |
| 5 | Left Atrial Appendage Occlusion Study(LAAOS) :results of a randomized controlled pilot study of left atrial appendage occlusion during coronary bypass surgery in patients at risk for stroke显示文摘 | Healey JS Crystal E Lamy A | 2005 | Am Heart J2005，150，： | 1 |
| 6 | Gastrointestinal function followingesophageetomy for malignancy 显示文摘 | Finley FJ Lamy A Clifton J | 1995 | Am J Surg1995，169，5： | 1 |
| 7 | Tribological investigation of textile fabrics 显示文摘 | BUENO M A LAMY B RENNER M | 1996 | Wear1996，195，1： | 1 |
| 8 | Combined inhibition of PDGF and VEGF receptors by ellagie acid ,a dietaryderived phe- nolic compound显示文摘 | Labrecque L Lamy S Chapus A | 2005 | Carcinogenesis2005，26，4： | 1 |
| 9 | Rationale and design of the coronary artery bypass grafting surgery off or on pump revascularization study: a large international randomized trial in cardiac surgery显示文摘 | Lamy A Deverreaux P J Prabhakaran D | 2012 | Am heart J2012，163，1： | 1 |
| 10 | Left atrial ap- pendage qcclusion study : results of a randomized controlledpilot study of left atrial appendage occlusion during coronary bypass surgery in patients at risk for stroke显示文摘 | HEALEY J S CRYSTAL E LAMY A | 2005 | Am Heart J2005，150，2： | 1 |
| 11 | Recent advances in the development of direct alcohol fuel cell (DAFC)显示文摘 | Lamy C Lima A LeRhun V | 2002 | Power Sources2002，105，2： | 1 |
| 12 | From seismic to reservoir properties with geostatistical inversion 显示文摘 | Lamy P Swaby P A Rowbotham P S | 1999 | SPE Reservoir Eval Eny1999，4，3： | 1 |
| 13 | Taking care of suicidal patients with new technologies and reaching-out means in the post-discharge period显示文摘Suicide is a global public health problem with over one million people dying by suicide each year worldwide.Research efforts have focused on developing and testing novel suicide prevention strategies employing recent technological advances.In order to provide a review regarding the role of new technologies(e.g.,postcards/letters,text messages,crisis cards,telephone contacts,online interventions) in suicide prevention,we searched Pub Med,Science Direct,Research Gate,and Crisis to identify all papers in English from 1977 to 2016.Our results indicated that brief contact interventions show promise in reducing the number of episodes of repeated self-harm and/or suicide attempts following discharge from the Emergency Department or psychiatric units.Innovative methods of contact(e.g.,text messages) are easily implemented by clinicians and received by patients in the period of post discharge and have been shown to be beneficial.However,more research employing randomized clinical trials investigating the potential benefits of these novel suicide prevention methods is warranted.Future researchers should continue improving and testing new technologies in the prevention of suicide. | Giulia Falcone Adele Nardella Dorian A Lamis Denise Erbuto Paolo Girardi Maurizio Pompili | 2017 | World Journal of Psychiatry2017，7，3： | 1 |
| 14 | Sonoehemieal degradation of phenol in dilute aqueous solutions:comparison of the reaction rates at 20 and 487 kHz 显示文摘 | Prtrier C Lamy M F Francony A | 1994 | The Joumal of Physical Chemistry1994，98，10： | 1 |
| 15 | Left atrial appendage occlusion study (LAAOS) : a randomized clinical trial of left atrial appendag occlusion during routine coronary artery by passgraft surgery for long term stroke prevention显示文摘 | Crystal E Lamy A Connolly SJ | 2003 | Am Heart J2003，145，1： | 1 |
| 16 | Pro-gastrin releasing peptide, neuron-specific enolase and chromogranin A as serum markers of small cell lung cancer显示文摘 | Lamy PJ Grenier J Kramar A | 2000 | Lung Cancer2000，29，3： | 1 |
| 17 | Hydroxyapatite coatings with a bond coat of biomedical implants by plasma projection 显示文摘 | Pierrc A C Heimann R B | 1996 | J Mater Res1996，11，： | 1 |
| 18 | Left Atrial Appendage Occlusion Study (LAAOS): a randomized clinical trial of left atrial appendage occlusion during routine coronary artery bypass graft surgery for long-term stroke prevention显示文摘 | Crystal E Lamy A Connolly SJ | 2003 | Am Heart J2003，145，1： | 1 |
| 19 | Biphasic effects of luteolin on interleukin-113-induced cyclooxygenase-2 expression in? glioblas- toma cells显示文摘 | Lamy S Moldovan PL Ben Saad A | 2014 | Biochim Biophys Acta2014，1853，1： | 1 |
| 20 | From Seismic to Reservoir Properties Using Geostatistical Inversion显示文摘 | Lamy P Swaby P A Rowbotham P S Dubrule O | | SPE:491470，，49： | 1 |
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