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| 1 | In Vivo Phosphorylation Site Mapping and Functional Characterization of Arabidopsis Phototropin 1显示文摘Phototropins (phot1 和 phot2 ) 是控制优化植物的光合的效率的回答的一个范围的蓝光的受体 kinases。察觉到的光被二个黄素绑定主题调停,作为 LOV1 和 LOV2 知道,在蛋白质的 N 终端区域以内定位了。经由 LOV2 的 Photoexcitation 导致 C 终端 kinase 领域并且因而的激活受体 autophosphorylation。然而,为 Arabidopsis phototropins 的 in-vivo phosphorylation 地点的知识在阐明正在缺乏并且阻碍了进步受体 phosphorylation 的功能的意义。我们从 Arabidopsis 净化了 phot1 并且由液体层析双人脚踏车团 spectrometry 识别了受体 phosphorylation 的 in-vivo 地点。导出 Arabidopsis 的 phot1 作为色基绑黄素 mononucleotide 并且是在 LOV2 (Ser58, Ser85, Ser350,和 Ser410 ) 在上游的定位的四个主要地点的 phosphorylated。不过,结构功能分析显示 phot1 的生物活动能被归因于包括蛋白质的 LOV2-kinase 区域的一个模块化的单位。因此,包括这里识别的受体 phosphorylation 的地点, LOV2 在上游的肽区域不看起来为受体发信号重要。由对比,这些区域可能为最大化是必要的有气孔的性能和 phot1 的可能导致光的本地化。 | Stuart Sullivan Catriona E. Thomson Douglas J. Lamont Matthew A. Jones John M. Christie | 2008 | Molecular Plant2008，1，1： | 11 |
| 2 | 863 genomes reveal the origin and domestication of chicken显示文摘Despite the substantial role that chickens have played in human societies across the world,both the geographic and temporal origins of their domestication remain controversial.To address this issue,we analyzed 863 genomes from a worldwide sampling of chickens and representatives of all four species of wild jungle fowl and each of the five subspecies of red jungle fowl(RJF).Our study suggests that domestic chickens were initially derived from the RJF subspecies Gallus gallus spadiceus whose present-day distribution is predominantly in southwestern China,northern Thailand and Myanmar.Following their domestication,chickens were translocated across Southeast and South Asia where they interbred locally with both RJF subspecies and other jungle fowl species.In addition,our results show that the White Leghorn chicken breed possesses a mosaic of divergent ancestries inherited from other subspecies of RJF.Despite the strong episodic gene flow from geographically divergent lineages of jungle fowls,our analyses show that domestic chickens undergo genetic adaptations that underlie their unique behavioral,morphological and reproductive traits.Our study provides novel insights into the evolutionary history of domestic chickens and a valuable resource to facilitate ongoing genetic and functional investigations of the world's most numerous domestic animal. | Ming-Shan Wang Mukesh Thakur Min-Sheng Peng Yu Jiang Laurent Alain Francois Frantz Ming Li Jin-Jin Zhang Sheng Wang Joris Peters Newton Otieno Otecko Chatmongkon Suwannapoom Xing Guo Zhu-Qing Zheng Ali Esmailizadeh Nalini Yasoda Hirimuthugoda Hidayat Ashari Sri Suladari Moch Syamsul Arifin Zein Szilvia Kusza Saeed Sohrabi Hamed Kharrati-Koopaee Quan-Kuan Shen Lin Zeng Min-Min Yang Ya-Jiang Wu Xing-Yan Yang Xue-Mei Lu Xin-Zheng Jia Qing-Hua Nie Susan Joy Lamont Emiliano Lasagna Simone Ceccobelli Humpita Gamaralalage Thilini Nisanka Gunwardana Thilina Madusanka Senasige Shao-Hong Feng Jing-Fang Si Hao Zhang Jie-Qiong Jin Ming-Li Li Yan-Hu Liu Hong-Man Chen Cheng Ma Shan-Shan Dai Abul Kashem Fazlul Haque Bhuiyan Muhammad Sajjad Khan Gamamada Liyanage Lalanie Pradeepa Silva Thi-Thuy Le Okeyo Ally Mwai Mohamed Nawaz Mohamed Ibrahim Megan Supple Beth Shapiro Olivier Hanotte Guojie Zhang Greger Larson Jian-Lin Han Dong-Dong Wu Ya-Ping Zhang | 2020 | Cell Research2020，30，8： | 7 |
| 3 | 心肌细胞钙波的影象观察显示文摘目的 :观察大鼠心肌细胞内钙波的影象及钙波在心肌细胞内及细胞间的传播。方法 :采用激光共聚焦显微镜及细胞内钙荧光染色的观测方法。结果 :1在激光共聚焦显微镜下观察了由钙荧光探针 Fluo- 3染色的心房肌及心室肌细胞的影象。 2观察了心肌细胞内钙在某一区域瞬时性增高的现象即钙波在心肌细胞内传播的动态影象 ,钙波的发生与细胞外钙浓度大小有关。3观察了钙波在心肌细胞与细胞间连接处的传播动态影象。结论 :心脏在静息时 (尤其高钙负荷时 )出现钙波是钙信号的一种调节机制。钙波具有在细胞内区域性、瞬时性增高 ,并较快在细胞内传播 ,亦可在细胞间传播。 | 臧伟进 于晓江 臧益民 Christine Lamont Gil Wier | 2001 | 心脏杂志2001，13，5： | 6 |
| 4 | 女性健康倡议单用雌激素试验中冠状动脉钙化与试验后心血管事件及死亡率的关系显示文摘参与女性健康倡议(women’s health initiative,WHI)单用雌激素(estrogen—alone,E—Alone)试验的年龄50~59岁的女性中,与安慰剂组相比,基线时随机使用合成雌激素的女性心肌梗死的风险和死亡率更低。 | 黄洁 叶鹏 Poornima IG Mackey RH Allison MA Manson JE Carr JJ LaMonte MJ Chang Y Kuller LH | 2017 | 中华高血压杂志2017，25，11： | 3 |
| 5 | Short-sale constraints and stock returns显示文摘 | Charles M Jones Owen A Lamont | 2002 | Journal of Financial Economics2002，，2： | 2 |
| 6 | Long-Term Survival Outcomes with Intravesical Docetaxel in the Management of Recurrent Nonmuscle Invasive Bladder Cancer After Previous Bacillus Calmette-Guérin Therapy显示文摘 | LaMont J. Barlow James M. McKiernan Mitchell C. Benson | 2013 | The Journal of Urology2013，，： | 2 |
| 7 | Quantity and Quality of Exercise for Developing and Maintaining Cardiorespiratory, Musculoskeletal, and Neuromotor Fitness in Apparently Healthy Adults: Guidance for Prescribing Exercise显示文摘 | Carol Ewing Garber Bryan Blissmer Michael R. Deschenes Barry A. Franklin Michael J. Lamonte I-Min Lee David C. Nieman David P. Swain | 2011 | Medicine & Science in Sports & Exercise2011，，7： | 2 |
| 8 | Coronary artery calcium score and coronary heart disease events in a large cohort of asymptomatic men and women 显示文摘 | LaMonte MJ FitzGerald SJ Church TS | 2005 | Am J Epidemiol2005，162，5： | 1 |
| 9 | Organizational Form and Environment: An Analysis of Between-form and Within-form Responses to Environmental Change显示文摘 | James J Hoffman Bruce T Lamont | 2000 | Strategic Management Journal2000，21，8： | 1 |
| 10 | Life below the gum line:pathogenic mechanisms of Porphyromonas gingivalis显示文摘 | Lamont RJ Jenkinson HF | 1998 | Microbiol Mol Biol Rev1998，62，4： | 1 |
| 11 | Pathogenesis and clinical manifestations of Clostridium difficile diarrhea and colitis显示文摘 | Farrell RJ LaMont JT | 2000 | Curr Top Microbiol Immunol2000，250，： | 1 |
| 12 | HOLSR:a hierarchical proactive routing mechanism for mobile Ad Hoc networks显示文摘 | Gonzalez L V Ying Ge Lamont I | 2005 | IEEE Communications Magazine2005，，： | 1 |
| 13 | Combined histopathological and molecular cytogenetic stratification of medulloblastoma patients 显示文摘 | Lamont J M McManamy C S Pearson A D | 2004 | Clin Cancer Res2004，10，： | 1 |
| 14 | Graduated compression stockingsto prevent deep vein thrombosis显示文摘 | Walker L Lamont S | 2008 | Nurs Stand2008，22，40： | 1 |
| 15 | Pre-treatment plasma pro-teomic markers associated with survival in oesophageal cancer显示文摘 | Kelly P Paulin F Lamont D | 2012 | British journal of cancer2012，106，5： | 1 |
| 16 | Fecal Transplantation for Recurrent C lostridium difficile Infection in Older Adults: A Review显示文摘 | Kristin E. Burke John T. Lamont | 2013 | J Am Geriatr Soc2013，，8： | 1 |
| 17 | Par- vovirus B19 infection in human pregnancy 显示文摘 | LAMONT R F SOBEL J D VAISBUCH E | 2011 | BJOG2011，118，2： | 1 |
| 18 | The im- pact of vitamin D in pregnancy on extraskeletal health in children: a systematic review 显示文摘 | Christesen H T Elvander C Lamont R F | 2012 | Acta Obstet Gynecol Scand2012，91，12： | 1 |
| 19 | Variation in se quence and expression of the avian FTO, and associa tion with glucose metabolism, body weight, fatness and body composition in chickens 显示文摘 | JIA X NIE Q LAMONT S J | 2012 | Int J (Lond)2012，36，8： | 1 |
| 20 | The congenital central hypoven- tilation syndrome ( CCHS ) : a late presentation 显示文摘 | Lamont T Pontier S Tetu L | 2012 | Rev Mal Re- spir2012，29，3： | 1 |
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