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| 1 | Dermatofibrosarcoma protuberans: from translocation to targeted therapy显示文摘Dermatofibrosarcoma protuberans(DFSP), the most common dermal sarcoma, is a low-grade, slow growing fibroblastic malignant neoplasm that most frequently affects middle aged adults and is characterized by a high local recurrence rate and a low propensity for metastasis. Wide surgical resection or Mohs micrographic surgery(MMS) are the preferred approaches for localized disease, while radiation therapy is warranted for inoperable disease or for cases with positive margins where re-excision is not possible. DFSP is generally regarded as refractory to conventional chemotherapy. Treatment options for systemic disease were limited until the discovery of a unique translocation, t(17;22)(q22;q13)(COL1A1;PDGFB) found in a majority of cases. In recent years, imatinib, a PDGFβR, ABL and KIT inhibitor, has revolutionized systemic therapy in DFSP. In this review, we summarize the epidemiological, clinical, histological and genetic characteristics of DFSP and update the readers on its current management. | Jonathan Noujaim Khin Thway Cyril Fisher Robin L.Jones | 2015 | Cancer Biology & Medicine2015，12，4： | 4 |
| 2 | Organic mulching promotes soil organic carbon accumulation to deep soil layer in an urban plantation forest显示文摘Background:Soil organic carbon(SOC)is important for soil quality and fertility in forest ecosystems.Labile SOC fractions are sensitive to environmental changes,which reflect the impact of short-term internal and external management measures on the soil carbon pool.Organic mulching(OM)alters the soil environment and promotes plant growth.However,little is known about the responses of SOC fractions in rhizosphere or bulk soil to OM in urban forests and its correlation with carbon composition in plants.Methods:A one-year field experiment with four treatments(OM at 0,5,10,and 20 cm thicknesses)was conducted in a 15-year-old Ligustrum lucidum plantation.Changes in the SOC fractions in the rhizosphere and bulk soil;the carbon content in the plant fine roots,leaves,and organic mulch;and several soil physicochemical properties were measured.The relationships between SOC fractions and the measured variables were analysed.Results:The OM treatments had no significant effect on the SOC fractions,except for the dissolved organic carbon(DOC).OM promoted the movement of SOC to deeper soil because of the increased carbon content in fine roots of subsoil.There were significant correlations between DOC and microbial biomass carbon and SOC and easily oxidised organic carbon.The OM had a greater effect on organic carbon fractions in the bulk soil than in the rhizosphere.The thinnest(5 cm)mulching layers showed the most rapid carbon decomposition over time.The time after OM had the greatest effect on the SOC fractions,followed by soil layer.Conclusions:The frequent addition of small amounts of organic mulch increased SOC accumulation in the present study.OM is a potential management model to enhance soil organic matter storage for maintaining urban forest productivity. | Xiaodan Sun Gang Wang Qingxu Ma Jiahui Liao Dong Wang Qingwei Guan Davey L.Jones | 2021 | Forest Ecosystems2021，8，1： | 2 |
| 3 | A Monte Carlo study of IMRT beamlets in inhomogeneous media显示文摘 | Andrew O.Jones Indra J.Das Frederick L.Jones Jr | | 0，，03： | 1 |
| 4 | Pharmacokinetics of N‐acetylcysteine are altered in patients with chronic liver disease显示文摘 | A. L.JONES D. R.JARVIE D.SIMPSON P. C.HAYES L. F.PRESCOTT | 2003 | Alimentary Pharmacology & Therapeutics2003，，4： | 1 |
| 5 | Trajectories of Alcohol Consumption Following Liver Transplantation显示文摘 | A.DiMartini M. A.Dew N.Day M. G.Fitzgerald B. L.Jones M. E.DeVera P.Fontes | 2010 | American Journal of Transplantation2010，，10： | 1 |
| 6 | Control of matrix metalloproteinase activity in cancer显示文摘 | J. L.Jones R. A.Walker | 1999 | Pathol1999，，4： | 1 |
| 7 | Randomized clinical trial of laparoscopic total (Nissen) versus posterior partial (Toupet) fundoplication for gastro‐oesophageal reflux disease based on preoperative oesophageal manometry显示文摘 | M. I.Booth J.Stratford L.Jones T. C. B.Dehn | 2007 | Br J Surg2007，，1： | 1 |
| 8 | DNA hypomethylation of karyoplasts for bovine nuclear transplantation*显示文摘 | Karen L.Jones JonathonHill Tae YoungShin LingLui MarkWesthusin | 2001 | Mol Reprod Dev2001，，2： | 1 |
| 9 | The control of carbon acquisition by roots显示文摘 | J. F.FARRAR D. L.JONES | 2008 | New Phytologist2008，，1： | 1 |
| 10 | Trajectories of Alcohol Consumption Following Liver Transplantation显示文摘 | A.DiMartini M. A.Dew N.Day M. G.Fitzgerald B. L.Jones M. E.DeVera P.Fontes | 2010 | American Journal of Transplantation2010，，10： | 1 |
| 11 | 水硅铀矿及其他常见铀矿的铀浸出动力学比较(英文)显示文摘水热合成并表征水硅铀矿,在此基础上对水硅铀矿在硫酸体系中的浸出过程进行研究,并将结果与其他相关的合成U^(4+)矿物如氧化铀(UO_2)和钛铀矿(UTi_2O_6)在类似条件下的浸出速率和浸出率进行比较。浸出时间对铀溶出影响的研究表明,水硅铀矿在36~48 h被完全浸出,该反应的活化能为38.4 kJ/mol。与水硅铀矿相比,氧化铀矿的溶出速率明显较快,可以在3 h内达到完全溶出(E_a=42~84 kJ/mol)。比较而言,合成钛铀矿的浸出速率较水硅铀矿的明显更低,其144 h铀的最大浸出率只有18%。上述3种矿物溶出速率和提取率的显著区别与文献报道相符合,即矿物的可溶出性为氧化铀>水硅铀矿>钛铀矿。在天然水硅铀矿中,由于杂质的存在,其可溶出性可能会被进一步抑制。 | H.S.REYNOLDS R.RAM M.I.POWNCEBY Y.YANG M.CHEN J.TARDIO L.JONES S.K.BHARGAVA | 2018 | Transactions of Nonferrous Metals Society of China2018，28，10： | 1 |
| 12 | Effects of variations in duodenal glucose load on glycaemic, insulin, and incretin responses in type 2 diabetes显示文摘 | J.Ma A. N.Pilichiewicz C.Feinle‐Bisset J. M.Wishart K. L.Jones M.Horowitz C. K.Rayner | 2012 | Diabetic Medicine2012，，5： | 1 |
| 13 | Deinking paper fibre application to agricultural land: soil quality enhancer or copper polluter?显示文摘 | S.Tandy J. C.Williamson M. A.Nason J. R.Healey D. L.Jones | 2008 | Soil Use and Management2008，，2： | 1 |
| 14 | 评Visual Studio 2005 Team System——团队协作开发的利器显示文摘许多年前,微软发布的Visual Basicl.0使得开发Windows软件的复杂性被大大降低了。到了推出Visual Basic 6.0的时候,微软使得上百万的程序员可以非常快速地开发出Client/Server应用程序。而前些时候发布的Visual Studio. | Bradley L.Jones | 2004 | 程序员2004，，7： | 0 |
| 15 | Fate of low-molecular-weight organic phosphorus compounds in the P-rich and P-poor paddy soils显示文摘Continuous application of organic fertilizers can cause accumulation of organic phosphorus(P)in soil,especially in the lowmolecular-weight organic phosphorus(LMWOP)forms.This organic P pool represents a potentially important source of P for both plants and microorganisms.To understand the effect of long-term fertilization(30 years)(P-rich soil)vs.fallowing(P-poor soil)on the bioavailability and fate of LMWOP in subtropical paddy soils,we determined the sorption and mineralization of 14 C-labeled adenosine,adenosine monophosphate(AMP),adenosine diphosphate(ADP),and adenosine triphosphate(ATP)in each soil.The contents of carbon,nitrogen,and P in the P-rich soil were more than two times greater than those in the P-poor soil.The mineralization rates of the LMWOP compounds were faster in the P-rich soil compared to the P-poor soil,and followed the order AMP>ADP>ATP.Using sterilized soil,all forms of adenosine-P were strongly sorbed to the solid phase and reached saturation in a short time,with the adsorbance increasing with the number of phosphate groups.We concluded that the mineralization of LMWOP compounds was repressed slightly by sorption to the solid phase,but only in the short term.Thus,LMWOP compounds serve as readily available sources of C for microorganisms,making P available for themselves as well as for the plants.However,P accumulation and the progressive saturation of the P sorption sites in highly fertile soils may increase the potential risk of P runoff. | LI Bao-zhen Anna GUNINA Mostafa ZHRAN Davey L.JONES Paul W.HILL HU Ya-jun GE Ti-da WU Jin-shui | 2021 | Journal of Integrative Agriculture2021，20，9： | 0 |
| 16 | 弗氏不完全佐剂可增加腹水及其单抗的产量显示文摘生产单抗的方法是小鼠腹腔注射分泌抗体的杂交瘤细胞,以腹水瘤的形式于其腹腔内增殖而得到含单抗的腹水。本文就预处理剂(降植烷或弗氏不完全佐剂)的选择和小鼠性别对改进单抗生产和减少动物费用作了比较。从134只弗氏不完全佐剂(FIA)预处理的小鼠收获的腹水量为697ml,从116只降植烷预处理的小鼠收获的腹水量为343ml,前者显著高于后者(p<0.02),且FIA预处理的小鼠仅10天(90%的动物需7天)可釆完腹水,而降植烷则需17天。两组腹水中IgG平均浓度(以EIA法测定)几乎没有差异(4.9mg/ml:4.6mg/ml),其量的差异(相当于每只鼠的产量)分别为FIA是25.5mg/只,降植烷是13.5mg/只。FIA预处理的小鼠每只腹水的平均产量也明显增多(P<0.02),未去势雄性小鼠和雌性小鼠间单抗产量无显著差异(22.1mg/只:23.1mg/只)。用FIA预处理的小鼠,单抗产量可提高到20mg/只以上,因而减少了所需小鼠数量,降低了生产单抗的费用。 | Stephen L.Jones 冯斌 | 1991 | 国外兽医学(畜禽疾病)1991，12，4： | 0 |
| 17 | Recent advances in the systemic treatment of gastrointestinal stromal tumors显示文摘Historical overview of the treatment for advanced gastrointestinal stromal tumors(GISTs)GISTs represent a relatively rare entity;however,GISTs are still the most common mesenchymal neoplasm in the gastrointestinal tract.The majority of GISTs express the transmembrane receptor,KIT,a product of the KIT proto-oncogene that can lead to uncontrolled cell proliferation and resistance to apoptosis1-3. | Robin L.Jones Marin Golcic | 2023 | Cancer Biology & Medicine2023，20，10： | 0 |
| 18 | 植物分子生物学研究领域的“圣经”:《植物生物化学与分子生物学》显示文摘 | Bob Buchanan Russell L.Jones Wilhelm Gruissem 瞿礼嘉 顾红雅 白书农 赵进东 陈章良 邓兴旺 | 2004 | 分子植物育种2004，2，2： | 0 |
| 19 | “世界杯”奖杯的曲折身世显示文摘3周后,32支国家足球队参加的“世界杯”将在南非开赛,而对每支球队而言,最高奖赏便是赢得这座久负盛名的、由18K黄金和孔雀石制成的奖杯。
“世界杯”奖杯目前正处在精心组织、赞助丰厚的环球巡游的最后阶段。它近期由纳尔逊·曼德拉保管。根据新闻描述,身穿防弹背心、手持冲锋枪的警察将在其30天南非巡游期间负责提供保护。 | Grahame L.Jones 谢秀栋 | 2010 | 英语文摘2010，，7： | 0 |
| 20 | Response of nitrogen fractions in the rhizosphere and bulk soil to organic mulching in an urban forest plantation显示文摘Nitrogen is an essential component in forest ecosystem nutrient cycling.Nitrogen fractions,such as dissolved nitrogen,ammonium,nitrate,and microbial biomass nitrogen,are sensitive indicators of soil nitrogen pools which affect soil fertility and nutrient cycling.However,the responses of nitrogen fractions in forest soils to organic mulching are less well understood.The rhizosphere is an important micro-region that must be considered to better understand element cycling between plants and the soil.A field investigation was carried out on the effect of mulching soil in a 15-year-old Ligustrum lucidum urban plantation.Changes in total nitrogen and nitrogen fractions in rhizosphere and bulk soil in the topsoil(upper 20 cm)and in the subsoil(20-40 cm)were evaluated following different levels of mulching,in addition to nitrogen contents in fine roots,leaves,and organic mulch.The relationships between nitrogen fractions and other measured variables were analysed.Organic mulching had no significant effect on most nitrogen fractions except for the rhizosphere microbial biomass nitrogen(MBN),and the thinnest(5 cm)mulching layer showed greater effects than other treatments.Rhizosphere MBN was more sensitive to mulching compared to bulk soil,and was more affected by soil environmental changes.Season and soil depth had more pronounced effects on nitrogen fractions than mulching.Total nitrogen and dissolved nitrogen were correlated to soil phosphorus,whereas other nitrogen fractions were strongly affected by soil physical properties(temperature,water content,bulk density).Mulching also decreased leaf nitrogen content,which was more related to soil nitrogen fractions(except for MBN)than nitrogen contents in either fine roots or organic mulch.Frequent applications of small quantities of organic mulch contribute to nitrogen transformation and utilization in urban forests. | Xiaodan Sun Gang Wang Yuqian Ye Qingxu Ma Qingwei Guan Davey L.Jones | 2021 | Journal of Forestry Research2021，32，6： | 0 |
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