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| 1 | Risk of complications and urinary incontinence following cytoreductive prostatectomy: a multi-institutional study显示文摘当时,新兴的证据建议了 cytoreductive 前列腺切除术(CRP ) 允许优异 oncologic 控制与照顾雄激素剥夺标准的电流相比治疗独自一个。然而,在变形前列腺癌症(mPCa ) 的 cytoreduction 的安全和利益没被证明。因此,我们评估了在最新与 mPCa 诊断的人跟随 CRP 的复杂并发症的发生。在四个第三级的外科的中心从 2006 ~ 2014 经历了 CRP 的 68 个病人的一个总数与为临床上局部性的前列腺癌症(PCa ) 经历了激进的前列腺切除术的 598 个人相比。尿不能自制被定义为任何垫的使用。CRP 有更长起作用的时间(200 min 对 140 min, P < 0.0001 ) 并且更高估计的血损失(250 ml 对 125 ml, P < 0.0001 ) 与控制组相比。然而,外套(8.82% 对 5.85%) 和主要复杂并发症率(4.41% 对 2.17%) 在二个组之间是可比较的。重要地,尿不能自制率在在外科以后 1 年在 CRP 组是显著地更高的(57.4% 对 90.8% , P < 0.0001 ) 。Univariate 逻辑分析证明估计的血损失在 unadjusted 模型两个都是 perioperative 复杂并发症的唯一的独立预言者(或:1.18;95% CI:1.02-1.37;P = 0.025 ) 并且外科调整类型的模型(或:1.17;95% CI:1.01-1.36;P = 0.034 ) 。在结论, CRP 比激进的前列腺切除术更挑战性、与尿不能自制的尤其是更高的发生联系。不过, CRP 是为选择谁的 PCa 病人的一个技术上可行、安全的手术与节点积极或多骨的转移在场当由富有经验的外科医生表现了时。未来的、多机构的临床的试用当前是在进行之中的验证这个概念。 | Dae Keun Kim Jaspreet Singh Parihar Young Suk Kwon Sinae Kim Brian Shinder Nara Lee Nicholas Farber Thomas Ahlering Douglas Skarecky Bertram Yuh Nora Ruel Wun-lae Kim Koon Ho Rha Isaac Yi Kim | 2018 | Asian Journal of Andrology2018，20，1： | 5 |
| 2 | Endoscopic submucosal dissection for early gastric cancer with undifferentiated histology: could we extend the criteria beyond?显示文摘 | Yi Young Kim Seong Woo Jeon JiYeon Kim Jung Chul Park Kwang Bum Cho Kyung Sik Park EunSoo Kim Yun Jin Chung Joong Goo Kwon Jin Tae Jung Eun Young Kim Kyeong Ok Kim ByungIk Jang Si Hyung Lee Chang Hun Yang | 2013 | Surgical Endoscopy2013，，12： | 3 |
| 3 | Whole-genome,transcriptome,and methylome analyses provide insights into the evolution of platycoside biosynthesis in Platycodon grandiflorus,a medicinal plant显示文摘Triterpenoid saponins(TSs)are common plant defense phytochemicals with potential pharmaceutical properties.Platycodon grandiflorus(Campanulaceae)has been traditionally used to treat bronchitis and asthma in East Asia.The oleanane-type TSs,platycosides,are a major component of the P.grandiflorus root extract.Recent studies show that platycosides exhibit anti-inflammatory,antiobesity,anticancer,antiviral,and antiallergy properties.However,the evolutionary history of platycoside biosynthesis genes remains unknown.In this study,we sequenced the genome of P.grandiflorus and investigated the genes involved in platycoside biosynthesis.The draft genome of P.grandiflorus is 680.1 Mb long and contains 40,017 protein-coding genes.Genomic analysis revealed that the CYP716 family genes play a major role in platycoside oxidation.The CYP716 gene family of P.grandiflorus was much larger than that of other Asterid species.Orthologous gene annotation also revealed the expansion ofβ-amyrin synthases(bASs)in P.grandiflorus,which was confirmed by tissue-specific gene expression.In these expanded gene families,we identified key genes showing preferential expression in roots and association with platycoside biosynthesis.In addition,wholegenome bisulfite sequencing showed that CYP716 and bAS genes are hypomethylated in P.grandiflorus,suggesting that epigenetic modification of these two gene families affects platycoside biosynthesis.Thus whole-genome,transcriptome,and methylome data of P.grandiflorus provide novel insights into the regulation of platycoside biosynthesis by CYP716 and bAS gene families. | Jungeun Kim Sang-Ho Kang Sin-Gi Park Tae-Jin Yang Yi Lee Ok Tae Kim Oksung Chung Jungho Lee Jae-Pil Choi Soo-Jin Kwon Keunpyo Lee Byoung-Ohg Ahn Dong Jin Lee Seung-il Yoo In-Gang Shin Yurry Um Dae Young Lee Geum-Soog Kim Chang Pyo Hong Jong Bhak Chang-Kug Kim | 2020 | Horticulture Research2020，7，1： | 2 |
| 4 | Living-Donor Liver Transplantation Associated With Higher Incidence of Hepatocellular Carcinoma Recurrence Than Deceased-Donor Liver Transplantation显示文摘 | Min-Su Park Kwang-Woong Lee Suk-Won Suh Tae You YoungRok Choi Hyeyoung Kim Geun Hong Nam-Joon Yi Choon-Hyuck David Kwon Jae-Won Joh Suk-Koo Lee Kyung-Suk Suh | 2014 | Transplantation Journal2014，，1： | 2 |
| 5 | Sequential spinal and intracranial dural metastases in gastric adenocarcinoma: A case report显示文摘Dural metastasis from primary gastric adenocarcinoma has been rarely reported, and its prognosis is very poor because it frequently leads to acute subdural hematoma. Here, we describe a case with sequential spinal and cranial dural metastases from gastric adenocarcinoma without subdural hematoma. A 43-yearold woman with gastric adenocarcinoma and wellcontrolled peritoneal carcinomatosis presented with back pain, right radiating leg pain, left facial palsy, and hearing loss. Magnetic resonance imaging of the spine and brain revealed dural masses at the lumbosacral junction with invasion to the L5 and S1 nerve roots and at the skull base with invasion to the internal auditory canal. She was treated with local radiotherapy, and her pain and neurologic symptoms improved after palliative radiotherapy. This is the first reported case of dural metastases of gastric adenocarcinoma of the spine and skull base but with a relatively indolent course and without subdural hematoma. | Hongsik Kim Kyung Sik Yi Won-Dong Kim Seung-Myoung Son Yaewon Yang Jihyun Kwon Hye Sook Han | 2018 | World Journal of Gastroenterology2018，24，5： | 2 |
| 6 | Relationship between gross motor function and daily functional skill in children with cerebral palsy显示文摘 | Kwon TG Yi SH Kim TW | 2013 | Annals of Rehabilitation Medicine2013，37，1： | 1 |
| 7 | Vehicle to vehicle distance and speed control using an electronic vacuum booster 显示文摘 | Yi K Kwon Y D | 2001 | JSAE Review2001，，22： | 1 |
| 8 | Vehicle-to-vehicle Distance and Speed Control Using an Electronic-vacuum Booster 显示文摘 | Kyongsu Yi Young Do Kwon | 2001 | JSAE Review2001，22，4： | 1 |
| 9 | Vehicle-to-vehicle distance and speed control using an electronic-vacuum booster显示文摘 | Yi K Kwon Y D | 2001 | JSAE Review2001，22，4： | 1 |
| 10 | Subfo- veal choroidal thickness as apotential pre- dictor of visual outcome and treatment re- sponse after intravtreal ranibizumab injec- tion for typical exudative age-related ma- cular degeneration显示文摘 | Kang HM Kwon H J Yi JH | 2014 | Am J Ophthalmol2014，157，5： | 1 |
| 11 | A vehicle control algorithm for stop-and-go cruise control显示文摘 | Yi K Hong J Kwon Y D | 2001 | Proc Instn Mech Engrs2001，215，： | 1 |
| 12 | Wear behavior of brazed WC/NiCrBSi (Co) composite coatings 显示文摘 | Lu Shan-ping Kwon Oh-yang Guo Yi | 2003 | Wear2003，254，： | 1 |
| 13 | Fermentation of milk and soymilk by Lactobacillus bulgaricus and Lactobacillus acidophilus enhances functionality for potential dietary management of hyperglycemia and hypertension显示文摘 | Apostolidis E Kwon YI Shetty K | 2007 | Food biotechnology2007，21，： | 1 |
| 14 | Wear behavior of brazed WC/NiCrBSi (Co) composite coatings 显示文摘 | Lu Shanping Kwon Ohyang Guo Yi | 2003 | Wear2003，，25： | 1 |
| 15 | Wear behavior of brazed WC/NiCrBSi(Co) composite coatings显示文摘 | Shan-Ping Lu Oh-Yang Kwon Yi Guo | 2003 | Wear2003，254，1： | 1 |
| 16 | 5 - HT2A receptor antago-nists inhibit hepatic stellate cell activation and facilitate apoptosis显示文摘 | KIM DC JUN DW KWON YI | 2013 | Liver Int2013，33，4： | 1 |
| 17 | Accidental ten times overdose administration of recombinant human erythropoietin(rh-EPO) up to 318,000 units a day in acute myocardial infarction:report of two cases显示文摘 | Shin DH Kwon YI Choi SI | 2006 | Basic Clin Pharmacol Toxicol2006，98，5： | 1 |
| 18 | Recurrence of hepatitis B is associated with cumulative corticosteroid dose and chemotherapy against hepatocellular carcinoma recurrence after liver transplantation显示文摘 | Nam‐Joon Yi Kyung‐Suk Suh Jai Young Cho Choon Hyuck Kwon Kwang‐Woong Lee Jae Won Joh Suk‐Koo Lee Soon Il Kim Kuhn Uk Lee | 2007 | Liver Transpl2007，，3： | 1 |
| 19 | Stable lipiodolized emulsions for hepatoma targeting and treatment by transcatheter arterial chemoembolization显示文摘 | YI SW KIM YH KWON IC | 1998 | J Control Release1998，50，13： | 1 |
| 20 | Comparison of lumbopelvic rhythm and flexion-relaxation response between 2 different low back pain subtypes显示文摘 | Kim MH Yi CH Kwon OY | 2013 | Spine2013，38，： | 1 |
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