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| 1 | Antioxidant activities of Indigofera cassioides Rottl.Ex.DC.using various in vitro assay models显示文摘Objective:To evaluate the antioxidant potential of methanolic leaf extract of Indigofera cassioides(MEIC) using various in vilro antioxidant assay systems.Methods:Antioxidant and free radical scavenging activity of MEIC was assayed by using different in vitro models like ABTS, DPPH,nitric oxide,superoxide,hydrogen peroxide and hydroxyl radical.Reductive ability of the extract was tested by the complex formation with potassium ferricyanide.Further total phenol and flavonoid contents of the crude extract were also determined.Rutin and ascorbic acid were used as standards.Results:MEIC exhibited potent and concentration dependent free radical scavenging activity in all the tested models.Reductive ability was also found to increase with increase in MEIC concentration.Total phenol and flavonoid content determination showed that the extract is rich in phenols and flavonoids.Conclusions:All the results of the in vitro antioxidant assays reveal potent antioxidant and free radical scavenging activity of the leaves of Indigofera cassioides,equivalent to that of standard ascorbic acid and rutin.This potent antioxidant activity may be attributed to its high phenolic and flavonoid contents. | R Senthil Kumar B Rajkapoor P Perumal | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，4： | 15 |
| 2 | Synthesis and evaluation of novel analogues of mangiferin as potent antipyretic显示文摘Objective:To screen different analogues of mangiferin pharmacologically for antipyretic activity. Methods:The naturally occurring xanthone glycoside mangiferin was isolated by column chromatography from the elhanolic extract of stem bark of Mangifera indica.Mangiferin was further converted to 5-(N-phenylamino methyleno) mangiferin.5-(N-p-chlorophenylamino methyleno) mangiferin,5-(N-2-methyl phenylamino methyleno) mangiferin.5-(N-p-methoxy phenylamino methyleno) mangiferin.5-(N,N-diphenylamino methyleno) mangiferin,5-(N-α-napthylamino methyleno) mangiferin and 5-(N-4-methyl phenylamino methyleno) mangiferin analogues.The synthesized compounds were further screened for antipyretic activity along with mangiferin at a dose level of 100 and 200 tng/kg.Mangiferin and its analogues were characterized by melting point and R_f value determination and through spectral technique like UV,IR,and NMR spectral analysis.Results:The antipyretic activity of mangiferin as well as all analogues was found to be more significant in at higher dose ie.200 mg/kg which was depicted thmugh a decrease in rectal temperature up to 3 h.Conclusions:The antipyretic activity of mangiferin and its analogues may be attributed to inhibition in synthesis of TNF-αand anti-oxidant activity associated with amelioration of inflammatory actions of cytokines. | Shashi Kant Singh Saurabh K Sinha SK Prasad R Kumar Bhawani S Bithu S Sadish Kumar P Singh | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，11： | 4 |
| 3 | Structural and luminescence enhancement properties of Eu^(3+)/Ag nanocrystallites doped SiO_2-TiO_2 matrices显示文摘We reported here the structural and optical characterisation of silver nanocrystallites/Eu3+ :SiO2-TiO2 matrices synthesised through sol-gel route. Structural characterisations were done by using energy dispersive spectroscopy (EDX), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), atomic force microscope (AFM) and transmission electron microscopy (TEM) measurements and optical characterisations were performed by absorption and emission spectroscopy. The TEM and XRD measurements confirmed the presence of nanocrystals. A broad absorption band was observed due to surface plasmon resonance of silver nanocrystals. The effect of silver nanocrystals on the emission spectrum of Eu3+ doped SiO2-TiO2 matrices was discussed. An attempt was made to explain this fluorescence enhancement by invoking phenomena such as energy transfer, asymmetry ratio, surface plasmon, surface roughness, crystallinity and grain boundary. Our analysis, based on the experimental results, suggested that all the phenomena except crystallinity and grain boundary had favourable effects on fluorescence enhancement. We also estimated the relevant parameters associated with the phenomena that affected the fluorescence emission from the Eu3+ ions in the matrix. It was seen that the theoretical estimate of fluorescence enhancement agreed well with the experimental estimate. | Arun Kumar K V Revathy K P Prathibha Vasudevan Sunil Thomas Biju P R Unnikrishnan N V | 2013 | Journal of Rare Earths2013，31，5： | 2 |
| 4 | Removal of arsenic from water by electrocoagulation显示文摘 | Kumar P R Chaudhari S Khilar K C | 2004 | Chemosphere2004，55，9： | 1 |
| 5 | Effect of the hydrophilic size on the structural phases of aqueous nonionic Gemini surfactant solutions显示文摘 | Nieh M P Kumar S K Fernando R H | 2004 | Langmuir2004，20，21： | 1 |
| 6 | Zinc biosorption on Tectona grandis L leaves biomass:Equilibrium and kinetic studies显示文摘 | Kumar Y P King P Prasad V S R K | 2006 | Chemical Engineering Journal2006，124，1： | 1 |
| 7 | Graft copolymerization of acrylonitrilc onto Cassia tora gum with eerie ammonium nitrate - nitricaeid as a redox initiator显示文摘 | Sharma B R Kumar V Soni P L | 2003 | Journal of Applied Polymer Science2003，，1： | 1 |
| 8 | Benzoxazine-bismaleimide blends; Curing and thermal properties显示文摘 | Santhosh Kumar K S Reghunadhan Nair C P Sadhana R | 2007 | European Polymer Journal2007，43，12： | 1 |
| 9 | Cumulative effect of continuous cropping, manuring and liming on oaicronutrient status in relation to soil characteristics 显示文摘 | Singh S K Kumar R Singh K P | 2010 | Environment and Ecology2010，28，2： | 1 |
| 10 | Evolution of porosity and surface acidity in montmorillonite clay on acid activation 显示文摘 | Kumar P Jasra R V | 1995 | Ind Eng Chem1995，，34： | 1 |
| 11 | Optimal control of production rate in a failure prone manufacturing system 显示文摘 | AKELLA R KUMAR P R | 1986 | IEEE Transactions Automatic Control1986，31，： | 1 |
| 12 | The Capacity of wireless networks显示文摘 | GUPTA P KUMAR P R | 2000 | IEEE Trans on Information Theory2000，46，： | 1 |
| 13 | Behaviour of micropolar cubic crystal due to various sources显示文摘 | Kumar R Ailawalia P | 2005 | Journal of Soundand Vibration2005，283，35： | 1 |
| 14 | A fuzzy goal programming approach for vendor selection problem in a supply chain 显示文摘 | Kumar M Vrat P Shankar R | 2004 | Computers & Industrial Engineering2004，46，3： | 1 |
| 15 | DNA barcodes can distinguish species of Indian mosquitoes (Diptera: Culicidae)显示文摘 | Kumar N P Rajavel A R Natarajan R | 2007 | J Med Entomol2007，44，1： | 1 |
| 16 | Solvent extraction of Hf(IV) from acidic chloride solutions using Cyanex 302显示文摘 | REDDY B R KUMAR J R RAJA K P REDDY A V | 2004 | Minerals Engineering2004，17，： | 1 |
| 17 | Benzoxazine-bisnudeimide blends: Curing and thermal properties 显示文摘 | Santhosh Kumar K S Reghunadhan Nair C P Sadhana R | 2007 | European Polymer Journal2007，43，12： | 1 |
| 18 | Flaw detection in radiographic weldment images using morphological approach 显示文摘 | ALAKNANDA ANAND R S KUMAR P | 2006 | NDTE International2006，39，1： | 1 |
| 19 | Biological fixation of commin- uted subtrochauteric fractures with proximal femur locking compres- sion plate显示文摘 | Saini P Kumar R Shekhawat V | 2013 | Injury2013，44，2： | 1 |
| 20 | 查看详情显示文摘 | Chung P W Kumar R Pruski M Lin V S Y | | 0，，09： | 1 |
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