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| 1 | Radiofrequency combined with immunomodulation for hepatocellular carcinoma: State of the art and innovations显示文摘Hepatocellular carcinoma(HCC)is the most common primary liver tumor and has been considered a very immunogenic tumor.The treatment with radiofrequency ablation(RFA)has been established as the standard ablative therapy for early HCC,and is currently recognized as the main ablative tool for HCC tumors<5 cm in size;however,progression and local recurrence remain the main disadvantages of this approach.To solve this clinical problem,recent efforts were concentrated on multimodal treatment,combining different strategies,including the combination of RFA and immunotherapy.This article reviewed the combination treatment of RFA with immunotherapy and found that this treatment strategy leads to an increased response of anti-tumor T cells,significantly reduces the risk of recurrence and improves survival rates compared to RFA alone.This review highlighted scientific evidence that supports the current recommendations for pre-clinical studies,and discuss the need for further research on this topic. | Adriano Carneiro da Costa Mikael Sodergren Kumar Jayant Fernando Santa Cruz Duncan Spalding Madhava Pai Nagy Habib | 2020 | World Journal of Gastroenterology2020，26，17： | 5 |
| 2 | Animal models of human colorectal cancer:Current status, uses and limitations显示文摘AIM: To make orthotopic colon cancer murine modelsa more clearly understood subject. The orthotopic tumor models have been found to be more relevant in replicating the human disease process as compared to heterotopic models, many techniques for making orthotopic colorectal murine models have been reported.METHODS: We evaluated the current literature for various reported orthotopic colon cancer models to understand their techniques, advantages and limitations. An extensive literature review was performed by searching the National Library of Medicine Database(Pub Med) using Me SH terms animal model; colon cancer; orthotopic model; murine model. Twenty studies related to colon cancer orthotopic xenograft model were evaluated in detail and discussed here. RESULTS: The detailed analysis of all relevant reports on orthotopic model showed tumor take rate between 42%-100%. While models using the enema technique and minimally invasive technique have reported development of tumor from mucosa with tumor take rate between 87%-100% with metastasis in 76%-90%.CONCLUSION: Over the years, the increased understanding of the murine models of human colon cancer has resulted in the development of various models. Each reported model has some limitations. These latest models have opened up new doors for continuing cancer research for not only understanding the colon cancer pathogenesis but also aid in the development of newer chemotherapeutic drugs as they mimic the human disease closely. | Vijay K Mittal Jasneet Singh Bhullar Kumar Jayant | 2015 | World Journal of Gastroenterology2015，21，41： | 5 |
| 3 | Comparative efficacy of tamsulosin versus tamsulosin with tadalafil in combination with prednisolone for the medical expulsive therapy of lower ureteric stones:a randomized trial显示文摘 | Kumar S Jayant K Agrawal S | 2014 | Korean J Urol2014，55，3： | 1 |
| 4 | Systemic meta-analysis assessing the short term applicability of early conversion to mammalian target of rapamycin inhibitors in kidney transplant显示文摘AIM To consolidate the present evidence of effectiveness in renal functioning and graft survival following early introduction of mammalian target of rapamycin(m TOR) inhibitors with or without calcineurin inhibitors(CNIs) in renal transplant recipients.METHODS We analysed the current literature following PROSPERO approval describing the role of immunosuppressive agent, m TOR inhibitors as an alternative to CNI within six months of renal transplant by searching the Pub Med, EMBASE, Cochrane, Crossref, and Scopus using Me SH terms. RESULTS Six articles of early withdrawal of CNI and introduction of m TOR-inhibitors within six months of renal transplantation were sought. Glomerular filtration rate(GFR) and serum creatinine were significantly better in m TOR inhibitor group with equivalent survival at 12 mo, even though Biopsy Proven Acute rejection was significantly higher in m TOR-inhibitor group. CONCLUSION The evidence reviewed in this meta-analysis suggests that early introduction m TOR-inhibitors substantial CNI minimization. The m TOR inhibitors such as everolimus and sirolimus, due to their complementary mechanism of action and favourable nephrotoxicity profile; better glomerular filtration, lower serum creatinine with equivalent survival. Having said that, due to the higher rejection rate, may influence the use of these regimens to patients with moderate to high immunological risk patients. | Jayant Kumar Isabella Reccia Tomokazu Kusano Bridson M Julie Ajay Sharma Ahmed Halawa | 2017 | World Journal of Transplantation2017，7，2： | 1 |
| 5 | Barrier properties of ordered multilayer polymer nanocomposites 显示文摘 | KU Bon-cheol BLUMSTEIN ALEXANDRE KUMAR JAYANT | 2004 | Dekker Encyclopedia of Nanoscience and Nanotechnology2004，14，： | 1 |
| 6 | Community resilience framework for an earthquake prone area in Baluchistan 显示文摘 | Syed Ainuddin Jayant Kumar Routray | 2012 | Inter- national Journal of Disaster Risk Reduction2012，2，： | 1 |
| 7 | Role of tamsulosin, tadalafil, and silodosin as the medical expulsive therapy in lower ureteric stone: a randomized trial (a pilot study)显示文摘 | KUMAR S JAYANT K AGRAWAL MM | 2015 | Urology2015，85，85： | 1 |
| 8 | Forgotten Kirschner wire causing severe hematuria显示文摘 | Kumar S Singh SK Jayant K | 2014 | Case Rep Urol2014，，30： | 1 |
| 9 | Batch and column study:adsorption of arsenate using untreat-ed laterite as adsorbent显示文摘 | Maiti Abhijit Dasgupta Sunando Basu Jayant Kumar | 2008 | Industrial&Engineering Chemisit-ry Research2008，47，5： | 1 |
| 10 | The fruit and veg- etable marketing chains in Thailand: policy impacts and implications 显示文摘 | Yanee Srimanee Jayant Kumar Routray | 2012 | International Joumal of Retail & Distribution Management2012，，： | 1 |
| 11 | Comparative efficacy of tamsulosin versus tamsulosin with tadalafil in combination with prednisolone for the medical expulsive therapy of lower ureletic stones: a ran- domized trial显示文摘 | Kumar S Jayant K Agrawal S | 2014 | Korean J Urol2014，55，3： | 1 |
| 12 | Left atrial myxoma, ruptured chordae tendinae causing mitral regurgitation and coronary artery disease显示文摘 | Bhupesh Kumar Ravi Raj Aveek Jayant Sachin Kuthe | 2014 | Annals of Cardiac Anaesthesia2014，，2： | 1 |
| 13 | The fruit and vegetablemarketing chains in Thailand:policy impacts and implications 显示文摘 | Yanee Srimanee Jayant Kumar Routray | 2012 | International Journal of Retail & Distribution Management2012，，40： | 1 |
| 14 | Enzymatically synthesized conducting polyaniline显示文摘 | Liu Wei Jayant Kumar Sukant Tripathy | 1999 | J Am Chem Soc1999，121，： | 1 |
| 15 | Role of ta- msulosin, tadalafil, and silodosin as the medical expul- sive therapy in lower ureteric stone: a randomized trial (a pilot study)显示文摘 | Kumar S Jayant K Aqrawal M M | 2015 | Urology2015，85，1： | 1 |
| 16 | An enzymatically synthesized conducting molecular complex of polyaniline and poly(vinylphosphonic acid)显示文摘 | Ramaswamy Nagarajan Sukant Tripathy Jayant Kumar | 2000 | Macromolecules2000，33，26： | 1 |
| 17 | In manipulating DNA conformation using intertwined conducting polymer chains显示文摘 | Ramaswamy Nagarajan Wei Liu Jayant Kumar | 2001 | Macromolecules2001，34，12： | 1 |
| 18 | The role of template in the enzymatic synthesis of conducting polyaniline显示文摘 | Wei Liu Ashok L Cholli Ramaswamy Nagarajan Jayant Kumar Sukant Tripathy Ferdinando F Bruno Lynne Samuelson | 1999 | J Am Chem Soc1999，121，11： | 1 |
| 19 | Framework for Energy Brokerage System with Reserve Market and Transmission Losses显示文摘 | Jayant Kumar Gerald Shedle | 1996 | IEEE Transactions on Power Systems1996，11，4： | 1 |
| 20 | Synthesis and properties of fullerene-polyvinyl pyridine conjugates for photovoltaic devices显示文摘 | Kumar Jayant Tripathy Sukant | 2001 | Journal of Macromolecular Science- Pure and Applied Chemistry2001，38，12： | 1 |
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