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| 1 | Wound healing activity of aqueous extract of Crotalaria verrucosa in Wistar albino rats显示文摘Objective:To evaluate the wound healing effect of aqueous extract of Crotalaria verrucosa(C. verrucosa) in rats.Methods:Three wound models including incision,excision and dead space wounds were used in this study.The parameters studied were breaking strength in incision models,granulation tissue dry weight,breaking strength and hydroxyproline content in dead space wounds,percentage of wound contraction and period of epithelialization in excision wound model.Results:Two doses of the extract with and without dexamethasone showed significant increases in mean hydroxyproline,total protein content and dry weight of granulation tissue but it was higher with dose 800 mg/kg comparing with the control.The dexamethasone treated group showed a significant(P<0.001) reduction in the wound breaking strength when compared to control group in incision type of wound model.Coadministration of C.verrucosa with dexamethasone significantly(P<0.001) increased the breaking strength compared to the dexamethasone treated only group.In excision wound model,the percentage of the wound contraction was significantly(P<0.01) increased by two doses of test extract on all the days except the lower dose which exhibited only on 12th,16th days of drug treatment and it also reversed the dexamethasone suppressed wound contraction.It significantly(P<0.001) reduced the time required for epithelialization and reversed the epithelialization delaying effect of dexamethasone (P<0.001).Conclusions:C.verrucosa was found to possess significant wound healing property. This was evident by decrease in the period of epithelialization,increase in the rate of wound contraction,skin breaking strength,and granulation tissue dry weight content.Hence C. verrucosa could be a good wound healing agent. | Meena Kumari Eesha BR Mohanbabu Amberkar Sarath babu Rajshekar Neelesh Kumar | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，10： | 3 |
| 2 | Reduction of N2O with CO over FeMFI zeolites: influence of the preparation method on the iron species and catalytic behavior 显示文摘 | Javier P rez-Ram rez Santhosh Kumar M Angelika Br ckner | 2004 | Journal of Catalysis2004，223，1： | 1 |
| 3 | Molecular regulation of vascular smooth muscle cell differentiation in development and disease显示文摘 | Owens GK Kumar MS Wamhoff BR | | 0，，03： | 1 |
| 4 | Molecular regulation of vascular smooth muscle cell differentiation in development and disease显示文摘 | Owens GK Kumar MS Wamhoff BR | 2004 | Physiol Rev2004，84，3： | 1 |
| 5 | Molecular regula- tion of vascular smooth muscle cell differentiation in devel- opment and disease 显示文摘 | Owens GK Kumar MS Warmhoff BR | 2004 | Physiol Rev2004，84，3： | 1 |
| 6 | General transcrip- tional coactivator PC4 activates p53 function 显示文摘 | Banerjee S Kumar BR Kundu TK | 2004 | Mol Cell Biol2004，24，5： | 1 |
| 7 | General transcriptional coactivator PC4 activates p53 function 显示文摘 | Banerjee S Kumar BR Kundu TK | 2004 | Mol Cell Biol2004，24，5： | 1 |
| 8 | Molecular regulation of vascular smooth muscle cell differentiation in development anddisease显示文摘 | Owens GK Kumar MS Wamhoff BR | 2004 | Physiol Rev2004，84，3： | 1 |
| 9 | Molecular regulation of vascular smooth muscle cell differentiation in development and disease显示文摘 | Owens GK Kumar MS Wamhoff BR | 2004 | Physiol Rev2004，84，3： | 1 |
| 10 | Data manage- ment in clinical research: an overview显示文摘 | Krishnankutty B BeUary S Naveen Kumar BR | 2012 | Indian J Pharmacol2012，44，2： | 1 |
| 11 | Molecular regulation of vascular smooth muscle cell differentiation in development and disease显示文摘 | Owens GK Kumar MS Wamhoff BR | 2004 | Physiol Rev2004，84，： | 1 |
| 12 | Molecular regulation of vascular smooth muscle cell differentiation in development and disease显示文摘 | Owens GK Kumar MS Wamhoff BR | 2004 | Physiol Rev2004，84，3： | 1 |
| 13 | 查看详情显示文摘 | Bréger J Meng Y. S Hinuma Y Kumar S.D.Kang K.Horn Y.S.Ceder G.Grey C.P | | 0，，20： | 1 |
| 14 | Molecular regulation of vascular smooth muscle cell differentiation development and disease 显示文摘 | Owwen GK Kumar MS Wamhoff BR | 2004 | Physiol Rev2004，84，3： | 1 |
| 15 | Molecular regulation of vascular smooth muscle cell differentiation in develop- ment and disease显示文摘 | Owens GK Kumar MS Wamhoff BR | 2004 | Physiol Rev2004，84，6： | 1 |
| 16 | Molecular regulation of vascular smooth muscle cell differentiation in development and disease 显示文摘 | Owens GK Kumar MS Wamhoff BR | 2004 | Physiol Rev2004，84，3： | 1 |
| 17 | Molecular regulation of vascular smooth musele cell differentiation in development and disease 显示文摘 | Owens GK Kumar MS Wamhoff BR | 2004 | Physiol Rev2004，84，3： | 1 |
| 18 | Molecular regulation of vascular smooth muscle cell differentiation in development and disease显示文摘 | Owens GK Kumar MS Wamhoff BR | 2004 | Physiol Rev2004，84，： | 1 |
| 19 | Molecular regulation of vascular smooth muscle cell differentiation in development and disease 显示文摘 | Owens GK Kumar MS Wamhoff BR | 2004 | Physiol Rev2004，84，3： | 1 |
| 20 | Molecular regulation of vascular smooth muscle cell differentiation in development and disease显示文摘 | Owens GK Kumar MS Wamhoff BR | 2004 | Physiol Rev2004，84，3： | 1 |
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