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152篇 您的检索式:作者名="Krapfe"
    题名 作者 年代 出处 被引量
1离子通道、磷酸化和哺乳动物精子获能显示文摘有性生殖动物需要精子和卵子之间进行精心协调的交流才能产生新的个体。精子获能是发生在女性生殖系统中的生殖细胞成熟的一个复杂现象,让精子能够和卵子联结并融合,是哺乳动物生育的必要条件。精子获能过程包括了质膜重组、离子渗透调节、胆固醇减少和许多蛋白质磷酸化状态的变化。研究精子离子通道的新工具能用更好的时空解析度将细胞内的离子变化和蛋白图像化,这些工具正在一步步阐明离子运输和磷酸化状态中的一系列调节是如何引起获能的。最近的证据表明有两条平行的通路调节引起获能的磷酸化发生。其中一条通路要求蛋白激酶A活化,另一条通路需要丝氨酸/苏氨酸磷酸酶失活。本文综述了精子获能所要求的离子运输参与和磷酸化信号处理。理解导致生育的分子机制,对于人们应对男性不育率升高、开发安全的以雄性配子为基础的避孕药、通过辅助生殖策略保持生物多样性都至关重要。Pablo E Visconti Dario Krapf Jose Luis de la Vega-Beltran Juan Jose Acevedo Alberto Darszon 2011Asian Journal of Andrology2011,13,3:19
2MRI characteristives of acute and subacute brainstem thalamic infarctions: value of T2 and diffusion-weighted sequences显示文摘Kuker W Weise L Krapf H 2002J Neurol2002,249,1:1
3Early out come of carotid angiopl asty and stenting with and without cerebral protection devices: a systematic review of the literature显示文摘Kastrup A Grosch el K Krapf H 2003Stroke2003,34,:1
4Fabrication and characterization of nanopore-based electrodes with radii down to 2 nm显示文摘Krapf D Wu M Y Smeets R M M 0,,01:1
5Family health climate scale (FHC-scale): development and validation显示文摘Niermann C Krapf F Renner B 2014IntJ Behav Nutr Phys Act2014,11,1:1
6Early outcome of carotid angioplasty and stenting with and without cerebarl protection devices:a systematic review of the literature显示文摘Kastrup A Groschel K Krapf H 2003Stroke2003,34,:1
7The Candida albicans Cdr2p ATP binding cassette (ABC) transporter confers resistance to easpofungin显示文摘Schuetzer Muehlbauer M Willinger B Krapf G 2003Mol Microbiol2003,48,22:1
8Azathioprine hypersensitivity mimicking Goodpasture's syndrome显示文摘Stetter M Schmidl M Krapf R 1994AmJ Kidney Dis1994,23,6:1
9Small rosarylike infarctions in thecentrum ovale suggest hemodynamic failure显示文摘 Widder B Skalej M 1998AJNR Am J Neuroradiol1998,19,:1
10Early outcome of carotid angioplasty and stenting with and without cerebral protection devices:a systematic review of the literature显示文摘Kastrup A Groschel K Krapf H 2003Stroke2003,34,:1
11Early outcome of carotid angio- plasly and stenting with and without cerebral protection devices:a sys- tematic review of the literature 显示文摘Kastrup A Croschel K Krapf H 2003Stroke2003,34,3:1
12Physical distribution service: A fundamental marketing concept 显示文摘Mentzer Comes Krapfe 1989Journal of the Academy of Marketing Science1989,,17:1
13Early outcome of carotidangioplasty and stenting with and without cerebral protection de vices: a systematic review of the literature 显示文摘Kastrup A Groschel K Krapf H 2003Stroke2003,34,3:1
14MRI characteristics of acute and suba- cute brainstem and thalamic infarctions: value of T2-and diffusion-weighted sequences显示文摘Kuker W Weise j Krapf H 2002J Neurol Sci2002,249,1:1
15Small rosarylike infarctions in the centrum ovale suggest hemodynamic failure显示文摘Krapf H Widder B Skalej M 0,,08:1
16The supratrochlear artery as an indicator of cerebral hemodynamics in carotid occlusion 显示文摘KRAPF H WIDDER B 1998Ultraschall Med1998,19,3:1
17Early outcome of carotidangioplasty and stenting with and without cerebral protection devices: a systematic review of the literature 显示文摘Kastrup A Grosehel K Krapf H 2003Stroke2003,34,:1
18Early outcome of carotid angioplasty and stenting with and without cerebral protection devices:a systematic review of the literature显示文摘Kastrup A Groschei K Krapf H 2003Stroke2003,34,4:1
19Early outcome of carotid angioplasty and stenting with and without cerebral protection devices:a systematic review of the literature显示文摘Kastrup A Groschel K Krapf H 2003Stroke2003,34,3:1
20Early outcome of carotid angioplasty and stenting with and without cerebral protection devices: a systematic review of the fiterature显示文摘Kastrup A Groschel K Krapf H 2003Stroke2003,34,3:1
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