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| 1 | Psychological controversies in gastroparesis: A systematic review显示文摘AIM To systematically review literature addressing three key psychologically-oriented controversies associated with gastroparesis. METHODS A comprehensive search of Pub Med, CINAHL, and PsycI NFO databases was performed to identify literature addressing the relationship between gastroparesis and psychological factors. Two researchers independently screened all references. Inclusion criteria were: an adult sample of gastroparesis patients, a quantitative methodology, and at least one of the following:(1) evaluation of the prevalence of psychopathology;(2) an outcome measure of anxiety, depression, or quality of life; and(3) evidence of a psychological intervention. Case studies, review articles, and publications in languages other than English were excluded from the current review. RESULTS Prevalence of psychopathology was evaluated by three studies(n = 378), which found that combined anxiety/depression was present in 24% of the gastroparesis cohort, severe anxiety in 12.4%, depression in 21.8%-23%, and somatization in 50%. Level of anxiety and depression was included as an outcome measure in six studies(n = 1408), and while limited research made it difficult to determine the level of anxiety and depression in the cohort, a clear positive relationship with gastroparesis symptom severity was evident.Quality of life was included as an outcome measure in 11 studies(n = 2076), with gastroparesis patients reporting lower quality of life than population norms, and a negative relationship between quality of life and symptom severity. One study assessed the use of a psychological intervention for gastroparesis patients(n = 120) and found that depression and gastric function were improved in patients who received psychological intervention, however the study had considerable methodological limitations. CONCLUSION Gastroparesis is associated with significant psychological distress and poor quality of life. Recommendations for future studies and the development of psychological interventions are provided. | Sally Woodhouse Geoff Hebbard Simon R Knowles | 2017 | World Journal of Gastroenterology2017，23，7： | 12 |
| 2 | Nitric oxide synthases: structure, function and inhibition显示文摘 | Alderton W K Cooper C E Knowles R G | 2001 | Biochem J2001，357，3： | 2 |
| 3 | Emergence in Asia of foot-and-mouth disease viruses with altered host range:characterization of alteration in the 3A protein显示文摘 | Knowles N J Davies P R Henry T | 2001 | J Virol2001，75，3： | 2 |
| 4 | Macrophage infiltration and angiogenesis in human malignancy显示文摘 | Knowles H Leek R Harris AL | 2004 | Novartis Found Syrup2004，256，： | 1 |
| 5 | Methane emission from fen, bog and swamp peatlands in Quebec 显示文摘 | Moore T R Knowles R | 1990 | Biogeochemistry1990，11，： | 1 |
| 6 | Utilization of aliphatic compounds by acidophilic heterotrophic bacteria: The potential for bioremediation of acidic wastewaters contaminated with toxic organic compounds and heavy metals显示文摘 | Knowles C J | 2000 | FEMS Microbiology Letters2000，192，： | 1 |
| 7 | Molecular epidemiology of foot-and-mouth disease virus显示文摘 | Knowles N J Samuel A R | 2003 | Virus Res2003，91，1： | 1 |
| 8 | Bucket trajectory classifi- cation of mining excavators显示文摘 | TIWARI R KNOWLES J DANKO G | 2013 | Automation in Construction2013，31，5： | 1 |
| 9 | Methane production and consumption in temperate and subarctic peat soils: response to temperature and Ph显示文摘 | Dunfield P Knowles R Dumont R Moore T R | 2003 | Soil Biology and Biochemistry2003，25，3： | 1 |
| 10 | Methane production and consumption in temperate and subarectic peat soils : response to temperature and pH显示文摘 | Dunfield P Knowles R Dumont R | 1993 | Soil Boil Biochem1993，25，： | 1 |
| 11 | Merging the Brands and Branding the Merger 显示文摘 | Ettenson R Knowles J | 2006 | MIT Sloan Management Review2006，47，4： | 1 |
| 12 | Nitric oxide synthases: structure, function and inhibition显示文摘 | Alderton W Cooper C Knowles R | 2001 | Biochem J2001，，357： | 1 |
| 13 | Macrophage infiltration and angio-genesis in human malignancy显示文摘 | Knowles H Leek R Harris AL | 2004 | Novartis Found Symp2004，256，： | 1 |
| 14 | On the driving traction acting on a surface of strain discontinuity in a continuum 显示文摘 | ABEYARATNE R KNOWLES J K | 1990 | J Mech Phys Solids1990，38，： | 1 |
| 15 | Foot-and-Mouth disease virus: Cause of the recent crisis for the UK livestock industry显示文摘 | Samuel A R Knowles N J | 2001 | Trends in genetics2001，17，8： | 1 |
| 16 | Nitric Oxide and Peroxynitrite Exert Distinct Effects on Mitochondrial Respiration Which are Differentially Blocked by Glutathione or Glucose显示文摘 | LIZASOAIN I MORO M A KNOWLES R G | 1996 | Biochem J1996，314，3： | 1 |
| 17 | Nitric oxide synthase in mammals显示文摘 | Knowles R G Moncada-S | 1994 | Biochem J1994，298，： | 1 |
| 18 | Newborn screening for con- genital heart defects : a systematic review and cost-effectiveness analy- sis 显示文摘 | Knowles R Griebsch I Dezateux C | 2005 | Health Technol Assess2005，9，1： | 1 |
| 19 | A homogeneous system for the photogeneration of hydrogen from water based on a platinum(Ⅱ) terpyridyl acetylide chromophore and a molecular cobalt catalyst显示文摘 | Du P Knowles K Eisenberg R | | 0，，15： | 1 |
| 20 | Nitric oxide synthases:structure,function and inhibition显示文摘 | ALDERTON W K COOPER C E KNOWLES R G | 2001 | Biochem J2001，357，3： | 1 |
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