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| 1 | Tight junctions in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer显示文摘Inflammatory bowel diseases are characterised by inflammation that compromises the integrity of the epithelial barrier. The intestinal epithelium is not only a static barrier but has evolved complex mechanisms to control and regulate bacterial interactions with the mucosal surface. Apical tight junction proteins are critical in the maintenance of epithelial barrier function and control of paracellular permeability. The characterisation of alterations in tight junction proteins as key players in epithelial barrier function in inflammatory bowel diseases is rapidly enhancing our understanding of critical mechanisms in disease pathogenesis as well as novel therapeutic opportunities. Here we give an overview of recent literature focusing on the role of tight junction proteins, in particular claudins, in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer. | Jonathan Landy Emma Ronde Nick English Sue K Clark Ailsa L Hart Stella C Knight Paul J Ciclitira Hafid Omar Al-Hassi | 2016 | World Journal of Gastroenterology2016，22，11： | 39 |
| 2 | 甘肃中部地区禾谷镰孢的变异研究显示文摘为掌握禾谷镰孢在甘肃中部地区的分布及变异情况,从根部表现有坏死和叶鞘发褐的小麦幼苗的不同部位.小麦地土壤及玉米籽粒.玉米茎秆上分离禾谷镰孢,并以形态学为基础,参照Nelson分类系统进行鉴定.结果表明,在分离到的43个镰刀菌菌株中,有14 个菌株经鉴定为禾谷镰孢,均从玉米茎秆上分离到,小麦根部.小麦叶鞘.小麦地土壤.玉米籽粒中分离到的镰刀菌中未见禾谷镰孢.将禾谷镰孢在特定条件下培养后,发现14 个禾谷镰孢菌株产生子囊壳的数量不同,为2-90个.在以Fg16为引物的PCR 反应中,随机选取的11个禾谷镰孢菌株都产生0.41kb的PCR 产物,而6个对照菌株都产生0.50kb的片段,证明引物Fg16可以区分禾谷镰孢菌株群体的遗传多态性.以Tri13为引物的PCR 反应显示,11个禾谷镰孢菌株以及3 个中国对照菌株都产生脱氧雪腐镰刀菌烯醇(DON)毒素,而3个澳大利亚对照菌株产生雪腐镰刀菌烯醇(NIV)毒素. | 李金花 纪莉景 柴兆祥 Knight T E Burgess L W | 2009 | 草业学报2009，18，1： | 3 |
| 3 | High serum levels of BAFF,APRIL,and TACI in common variable immunodeficiency显示文摘 | Radigan L Marron T | 2007 | Clin Immunol2007，124，： | 1 |
| 4 | Multiparticle generalization of entanglement swapping 显示文摘 | BOSE S VEDRAL V KNIGHT P L | 1998 | Phys Rev1998，，： | 1 |
| 5 | Constructed wetlands for livestock wastewater management显示文摘 | Knight R L Payne Jr V W E Borer R E | 2000 | Ecological Engineering2000，15，： | 1 |
| 6 | Neutrophilia and congestive heart failure after acute myocardia linfarction显示文摘 | Kyne L Hausdorff J M Knight E | 2000 | Am Heart J2000，139，： | 1 |
| 7 | The role of epithelial injury and repair in the origins of asthma 显示文摘 | Haekett T L Knight D A | 2007 | Curr Opin Allergy Clin Immunol2007，7，1： | 1 |
| 8 | Intrinsic decoherece in the atom-field interaction 显示文摘 | Moya-Cessa H Knight P L | 1993 | Phys Rev A1993，48，5： | 1 |
| 9 | Pericentric inversion 9-incidence and clinical significance 显示文摘 | eo SH Tan M Knight L | 1995 | Ann Acad Med Singapore1995，24，2： | 1 |
| 10 | A systematic re- view of motivational interviewing in physical health care settings 显示文摘 | Knight KM McGowan L Dickens C | 2006 | Br J Health Psychol2006，11，2： | 1 |
| 11 | Mycophenolate mofetil decreases acute rejection and May improve graft survival in renal transplant recipients when compared with azathioprine : a systematic review 显示文摘 | Knight SR Russell NK Barcena L | 2009 | Transplantation2009，87，6： | 1 |
| 12 | Fluorescence intensity and squeezing in a driving three-level atom:ladder case显示文摘 | Ficek Z Dalton B J Knight P L | 1995 | Phys Rev1995，51，5： | 1 |
| 13 | A comparison of prediction equations for estimating glomerular filtration rate in adults without kidney disease显示文摘 | Julie Lin Eric L Knight | 2003 | J Am Soc Nephrol2003，14，： | 1 |
| 14 | Performance assessment of a nuclear waste repository: Upscaling coupled hydro-mechanical properties for far-field transport analysis 显示文摘 | Blum P Mackay R Riley M S Knight J L | 2005 | International Journal of Rock Mechanics and Mining Sciences2005，42，56： | 1 |
| 15 | Atomic Entanglement and Bell' s Inequality Violation 显示文摘 | KUDRYVTSEV I K KNIGHT P L | 1993 | J M od Opt1993，40，： | 1 |
| 16 | On the mechanism of crystalline polymorph selection by polymer heteronuclei 显示文摘 | LOPEZ-MEJIAS V KNIGHT J L BROOKS C L | 2011 | Langmuir2011，27，12： | 1 |
| 17 | Increasing Urban Wage Inequality in China 显示文摘 | Knight J Song L | 2003 | Economics of Transition2003，11，4： | 1 |
| 18 | Selectivesurvival of naturally occurring human CD4+ CD25 +Foxp3 + regulatory T cells cultured with rapamycin 显示文摘 | Strauss L Whiteside TL Knights A | 2007 | JImmunol2007，178，1： | 1 |
| 19 | Expanding the Donor Pool with the Use of En Bloc Pediatric Kidneys into Adult Recipients显示文摘 | Burrows L Knight R Schanzer H | 1996 | Transplant Proc1996，28，1： | 1 |
| 20 | The Shc-related adaptor protein, Sck, forms a complex with the vascularendothelial growth-factor receptor KDR in transfected cells显示文摘 | Warner A J Lopez-Dee J Knight E L | 2000 | Biochem J2000，347，2： | 1 |
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