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| 1 | Utility of WT1 as a reliable tool for the detection of minimal residual disease in children with leukemia显示文摘 | Kletzel M Olzewski M Huang W | 2001 | Pcdiatr Dev Pathol2001，5，3： | 1 |
| 2 | Treatment of high - risk neuroblastoma with triple - tandem high - dose therapy and stem - cell rescue : Results of the Chicago Pilot II Study 显示文摘 | Kletzel M Katzenstein HM Haut PR | 2002 | J Clin Oncol2002，20，9： | 1 |
| 3 | Paroxysmal nocturnal hemoglobinuria presenting as recurrent hemolytic uremic syndrome显示文摘 | Kletzel M Arnold WC Berry DH | | 0，，： | 1 |
| 4 | Response to paclitaxel, topotecan, and topotecan-cyclophosphamide in children with untreated disseminated neuroblastoma treated in an upfront phase I investigational window: a pediatric oncology group study显示文摘 | Kretschmar CS Kletzel M Murray K | 2004 | J Clin Oncol2004，22，20： | 1 |
| 5 | Correction of enzyme levels with allogeneie hematopoeitic progenitor cell transplantation in Niemann-Piek type B显示文摘 | Schneiderman J Thormann K Charrow J Kletzel M | 2007 | Pediatr Blood Cancer2007，49，7： | 1 |
| 6 | The Quinoxaline Anti-tumor Agent(R+)XK469Inhibits Neuroblastoma Tumor Qrowth显示文摘 | Kakodkar N C Peddinti R Kletzel M | 2011 | Pediatric Blood&Cancer2011，56，1： | 1 |
| 7 | Outcomes of the POG 9340/9341/9342 trims for children with high-risk neuroblastoma: a report from the Children's Ontology Group显示文摘 | Zage PE Kletzel M Murray K | 2008 | Pediatr Blood Cancer2008，51，： | 1 |
| 8 | Utility of WT1 as a reliable tool for the detection of minimal residual disease in children with leukemia显示文摘 | Kletzel M Olzewski M Huang W | 2002 | Pediatr Dev Pathol2002，5，3： | 1 |
| 9 | Cytokine-mobilized allogeneic peripheral blood stem cell transplants in children result rapid engraftment and a high incidence of chronic GVHD显示文摘 | Wiley J Kletzel M | 2000 | Bone Marrow Transplant2000，25，1： | 1 |
| 10 | Cytokine-mobilized allogeneic peripheral blood stem cell transplants in children result in rapid engraftment and a high incidence of chronic GVHD显示文摘 | Levine JE Wiley J Kletzel M | 2000 | Bone Marrow Transplant2000，25，1： | 1 |
| 11 | A flow cytometric technique using thiazole orange to detect platelet engraftment fol owing pediatric stem-cel transplants显示文摘 | Figuerres E Olszewski M Kletzel M | | 0，，04： | 1 |
| 12 | Allogeneic hematopoetic stem cell transplantation in pediatric myelodysplastic syndromes:improved outcomes for de novo disease显示文摘 | Andolina JR Kletzel M Tse WT | | 0，，03： | 1 |
| 13 | Early elevation of C-reactive protein correlates with severe infection and nonrelapse mortality in children undergoing allogeneic stem cell transplantation 显示文摘 | Mcneer JL Kletzel M Rademaker A | 2010 | Biol Blood Marrow Transplant2010，16，3： | 1 |
| 14 | Outcomes of the POG 9340/ 9341/9342 trials for children with high-risk neuroblastoma: a report from the Children' s Oncology Group 显示文摘 | Zage PE Kletzel M Murray K | 2008 | Pediatr Blood Cancer2008，51，6： | 1 |
| 15 | 低强度造血干细胞移植治疗儿童非恶性疾病 | Jacobsohn D.A. Duerst R. Tse W. Kletzel 刘健 | 2005 | 世界核心医学期刊文摘(儿科学分册)2005，0，1： | 0 |
| 16 | 按照Chicago PilotⅡ方案治疗后神经母细胞瘤局部控制好坏与手术切除范围无明显关系显示文摘Background: Our aim was to investigate the impact of the extent of surgical resection on local recurrence and survival in high-risk patients treated with the Chicago Pilot II protocol. Methods: Retrospective chart review was performed on 30 patients enrolled in the Chicago Pilot II protocol between 1995 and 2003. Variables studied were location of tumor, extent of resection, timing and location of recurrence, MYCN amplification, surgical complications, event-free survival, and overall survival (OS).Operative reports and postoperative meta-iodobenzylguanidine scans were used to assess extent of resection. Complete resection (CR) was defined as no gross residual tumor including primary and nodal disease. Results: Three-year event-free survival and OS of this cohort of 30 patients was 58%and 82%, respectively. Only 1 patient developed a local recurrence, whereas metastatic recurrent disease was observed in 13 (43%)-of the 30; and this subset had a significantly worse OS (23%vs 94%, P = .001). The most common relapse location was in bone. Patients with incomplete resection (IR) (11/30) and CR (19/30) had recurrence rates of 64%(7/11) and 32%(6/19, P = .12), respectively. Event-free survival was significantly better for patients with CR (68%) vs IR(27%; P = .05; odds ratio, 2.9). Overall survival rates for patients with CR vs IR were 68%vs 55%, respectively (P = .25). Conclusions: Recurrence rate was the significant determinant of survival. Patients with CR had lower recurrence rates; however, they did not have improved local control. Final outcome of patients with unfavorable neuroblastoma will be determined by metastatic recurrence, not by extent of resection. | Browne M. Kletzel M. Cohn S.L. M. Reynolds 虎小毅 | 2006 | 世界核心医学期刊文摘(儿科学分册)2006，2，5： | 0 |
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