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| 1 | Pharmacogenetic studies update in type 2 diabetes mellitus显示文摘Type 2 diabetes mellitus(T2DM) is a silent progressive polygenic metabolic disorder resulting from ineffective insulin cascading in the body. World-wide, about 415 million people are suffering from T2DM with a projected rise to 642 million in 2040. T2DM is treated with several classes of oral antidiabetic drugs(OADs) viz. biguanides, sulfonylureas, thiazolidinediones, meglitinides, etc. Treatment strategies for T2DM are to minimize long-term micro and macro vascular complications by achieving an optimized glycemic control. Genetic variations in the human genome not only disclose the risk of T2DM development but also predict the personalized response to drug therapy. Inter-individual variability in response to OADs is due to polymorphisms in genes encoding drug receptors, transporters, and metabolizing enzymes for example, genetic variants in solute carrier transporters(SLC22A1, SLC22A2, SLC22A3, SLC47A1 and SLC47A2) are actively involved in glycemic/HbA1c management of metformin. In addition, CYP gene encoding Cytochrome P450 enzymes also play a crucial role with respect to metabolism of drugs. Pharmacogenetic studies provide insights on the relationship between individual genetic variants and variable therapeutic outcomes of various OADs. Clinical utility of pharmacogenetic study is to predict the therapeutic dose of various OADs on individual basis. Pharmacogenetics therefore, is a step towards personalized medicine which will greatly improve the efficacy of diabetes treatment. | Shalini Singh Kauser Usman Monisha Banerjee | 2016 | World Journal of Diabetes2016，7，15： | 5 |
| 2 | The influence of behavioural and organisational characteristics on the success of international strategic alliances 显示文摘 | Kauser S Shaw V | 2004 | International Marketing Review2004，21，1： | 1 |
| 3 | Role of endogenous nitric oxide in progression of atherosclerosis in apolipoprotein E-deficient mice 显示文摘 | da Cunha V Fitch R | 2000 | Am J Physiol Heart Circ Physiol2000，278，5： | 1 |
| 4 | A fully functional proopiomelanocortin/melanocortin-1 receptor system regulates the differentiation of human scalp hair follicle melanocytes 显示文摘 | Kauser S Thody AJ Schallreuter KU | 2005 | Endocrinology2005，146，2： | 1 |
| 5 | Role of estrogen receptors in the vascular system显示文摘 | Rubanyi GM Kauser K Johns A | | 0，，02： | 1 |
| 6 | The Influence of Behavioral and Organizational Characteristics on the Success of International Strategic Alliances 显示文摘 | Kauser S Shaw V | 2004 | International Marketing Review2004，21，1： | 1 |
| 7 | Role of estrogen receptors in the vascular system 显示文摘 | Rubanyi GM Kauser K Johns A | 2002 | Vascul Pharmacol2002，38，2： | 1 |
| 8 | Proopiomelanocortin (POMC), the ACTI-I/melanocortin precursor, is secreted by hu- man epidermal keratinocytes and melanocytes and stimulates mel- anogenesis显示文摘 | Rousseau K Kauser S Pritchard LE | 2007 | FASEB J2007，21，8： | 1 |
| 9 | The changing patterns of international strategic alliance activity by British firms 显示文摘 | Shaw V Kauser S | 2000 | Journal of General Management2000，25，4： | 1 |
| 10 | Estrogen inhibits the initiation of fatty streaks throughout the vasculature but does not inhibit intra-plaque hemorrhage and the progression of established lesions in apolipoprotein E deficient mice 显示文摘 | Rosenfeld ME Kauser K Martin-Mc Nuhy BP | 2002 | Atherosclerosis2002，164，： | 1 |
| 11 | Simple and rapid method to isolate and culture follicular papillae from human scalp hair follicles 显示文摘 | Magerl M Kauser S Paus R | 2002 | Experi Dermat2002，11，4： | 1 |
| 12 | Plasma Homocysteine level and its clinical correlation with type 2 diabetes mellitus and its complications显示文摘 | Satyendra Kumar Sonkar Gyanendra Kumar Sonkar Deepika Soni Dheeraj Soni Kauser Usman | 2014 | International Journal of Diabetes in Developing Countries2014，，： | 1 |
| 13 | Estrogen inhibits the initiation of fatty streaks throughout the vasculature but does not inhibit intra-plaque hemorrhage and the progression of established lesions in apolipoprotein E deficient mice 显示文摘 | Rosenfeld ME Kauser K McNulty BM | | Atheros0，，： | 1 |
| 14 | Pefformaneeof transverse flow bubbleless membrane aerator显示文摘 | Steven R Boyce Kauser Jahan | 1997 | Toxicological and Environmental Chemistry1997，64，： | 1 |
| 15 | A fully functional proopiomelanocortin/melanocortin1 receptor system regulates the differentiation of human scalp hair follicle melanocytes显示文摘 | KAUSER S THODY A J SCHALLREUTER K U | 2004 | Endocrinology2004，146，53： | 1 |
| 16 | Rhizobium,Bradyrhizobium and Agrobacterium strains isolated from cultivated legumes显示文摘 | SOHAIL H SUMERA Y KAUSER A M | 2004 | Biology and Fertility of Soils2004，39，3： | 1 |
| 17 | Vascular estrogen receptors and endothelium-derived nitric oxide (NO) production in the mouse aorta: gender difference and effect of estrogen receptor gene disruption显示文摘 | Freay AD Kauser K | 1997 | J Clin Invest1997，99，10： | 1 |
| 18 | Effects of estrogen on endothelial function and angiogenesis 显示文摘 | Rubanyi GM Johns A Kauser K | 2002 | Vasc Pharmacol2002，38，： | 1 |
| 19 | Comparative genomics of Helicobacter pylori isolates recovered from ulcer disease patients in England显示文摘 | Kauser F Hussain M A Ahmed I Srinivas S | 2005 | BMC Microbiol2005，5，： | 1 |
| 20 | Facters affecting the nonionic surfactant-ehanced biodegradation of phenanthrene显示文摘 | Kauser J 1997 | 1997 | Water Environ Res1997，69，3： | 1 |
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