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| 1 | Breath and string test: A diagnostic package for the identification of treatment failure and antibiotic resistance of Helicobacter pylori without the necessity of upper gastrointestinal endoscopy显示文摘AIM: Helicobacter pylori ( H pylofi) resistance after failed eradication has a major impact on the outcome of a further treatment regimen. The aim of this study was to assess the validity of a non-invasive strategy using the 13C-urea breath test (UBT) and the gastric string test in identifying post-treatment resistance of Hpylori.METHODS: The UBT was routinely performed 4 to 6 wk after H pylorieradication therapy. Forty-two patients (24 females, 18 males, mean age 48 years) with a positive UBT were included in the study. A gastric string test using a capsule containing a 90 cm-long nylon fiber was performed.Before the capsule was swallowed, the free end of the string was taped to the cheek. After one hour in the stomach, the string was withdrawn. The distal 20 cm of the string was inoculated onto an agar plate and processed under microaerophilic conditions. Following the string test, upper gastrointestinal endoscopy was performed to obtain gastric biopsies for conventional culture.RESULTS: H pyloriwas successfully cultured from the gastric string in 34 patients (81%), but not in 5 patients due to contamination with oropharyngeal flora. Hpyloriwas cultured from the gastric biopsies obtained at endoscopy in 39 patients (93%).CONCLUSION: The UBT followed by the gastric string test in the case of treatment failure is a valid diagnostic strategy with the aim of determining the post-therapeutic antibiotic resistance of Hpyloriwith little inconvenience to the patient.Upper GI-endoscopy can be avoided in several cases by applying consequently this diagnostic package. | Andreas Leodolter Kathlen Wolle Ulrike von Arnim Stefan Kahl Gerhard Treiber Matthias P.Ebert Ulrich Peitz Peter Malfertheiner | 2005 | World Journal of Gastroenterology2005，11，4： | 10 |
| 2 | Prevalence of H pylori associated 'high risk gastritis' for development of gastric cancer in patients with normal endoscopic findings显示文摘AIM: To investigate the prevalence of H pylori associated corpus-predominant gastritis (CPG) or pangastritis, severe atrophy, and intestinal metaplasia (IM) in patients without any signifi cant abnormal fi ndings during upper- GI endoscopy. METHODS: Gastric biopsies from 3548 patients were obtained during upper GI-endoscopy in a 4-year period. Two biopsies from antrum and corpus were histologically assessed according to the updated Sydney-System. Eight hundred and forty-fi ve patients (mean age 54.8 ± 2.8 years) with H pylori infection and no peptic ulcer or abnormal gross fi ndings in the stomach were identifi ed and analyzed according to gastritis phenotypes using different scoring systems. RESULTS: The prevalence of severe H pylori associated changes like pangastritis, CPG, IM, and severe atrophy increased with age, reaching a level of 20% in patients of the age group over 45 years. No differences in frequencies between genders were observed. The prevalence of IM had the highest increase, being 4-fold higher at the age of 65 years versus in individuals less than 45 years. CONCLUSION: The prevalence of gastritis featuring at risk for cancer development increases with age. These findings reinforce the necessity for the histological assessment, even in subjects with normal endoscopic appearance. The age-dependent increase in prevalence of severe histopathological changes in gastric mucosa, however, does not allow estimating the individual risk forgastric cancer development-only a proper follow-up can provide this information. | Andreas Leodolter Matthias P Ebert Ulrich Peitz Kathlen Wolle Stefan Kahl Michael Vieth Peter Malfertheiner | 2006 | World Journal of Gastroenterology2006，12，34： | 4 |
| 3 | Enhancing Citizen Participation:Panel Designs,Perspectives,and Policy Formation显示文摘 | Kathlene L Martin J | | 0，，01： | 1 |
| 4 | Solid acid catalyzed biodiesel production from waste cooking oil显示文摘 | Kathlene Jacobson Rajesh Gopinath Lekha Charan Meher | 2008 | Environmental2008，85，12： | 1 |
| 5 | Enhaneeing citizen participation:Panel designs ,perspectives, and policy formation 显示文摘 | KATHLENE L MARTIN J A | 1991 | Journal of Policy Analysis and Management1991，10，： | 1 |
| 6 | Power and Influence in State Legislative Policymaking: The Interaction of Gender and Position in Committee Hearing Debates显示文摘 | Lyn Kathlene | 1994 | American Political Science Review1994，，3： | 1 |
| 7 | Vaccines with iuterleukin- 12 - transduced acute myelooid leukemia cells elicit very potent therapeutic and long-lasting protective immunity 显示文摘 | Kyriaki Dunussi-Joannopoulos Kathlene Runyon Jamie Erickson | 1999 | Blood1999，94，12： | 1 |
| 8 | Hepatitis B virus and hepatitis C virus services offered by substance abuse treatment programs in the United States显示文摘 | Edmund J. Bini Steven Kritz Lawrence S. Brown Jim Robinson Donald Calsyn Don Alderson Kathlene Tracy Patrick McAuliffe Cheryl Smith John Rotrosen | 2012 | Journal of Substance Abuse Treatment2012，，4： | 1 |
| 9 | Enhancing citizen participation:Panel designs,perspectives,and policy formation显示文摘 | Kathlene L Martin J A | 1991 | Journal of Policy Analysis and Management1991，，10： | 1 |
| 10 | Identification of a potential HIV-induced source of bystander-mediated apoptosis in T cells: Upregulation of TRAIL in primary human macrophages by HIV-1 tat显示文摘 | Mingjie Zhang Xingxiang Li Xiaowu Pang Linna Ding Owen Wood Kathlene Clouse Indira Hewlett Andrew I. Dayton | 2001 | Journal of Biomedical Science2001，，3： | 1 |
| 11 | Enhancing Citizen Participation: Panel Designs, Perspectives, and Policy Formation 显示文摘 | Kathlene L Martin J A | 1997 | Journal of policy Analysis and Management1997，，10： | 1 |
| 12 | Enhancing Citizen Participation:Panel Designs,Perspectives,and Policy Formation显示文摘 | Kathlene L Martin J.A | | 0，，： | 1 |
| 13 | Winter's Open Door Policy显示文摘It's been relly cold lately in Bejing So cold that when temperaures tumed rlaivedy nomal for dhe time of yoar-hoveing just cidher side of 0C,it felt poitively balmy,warm cnough to it outside and sip a coffe.The fist thingI knew about the etrene cold wave was when a food delivery app sent me a text message,unging is ptrons to keep sufe.“We would lik to warmly recommend you t keep warm,”it sid.I didn't know ifthis message was intended to enoourage 1us to stay inside and order takcou,thus xposing is poor delivery drivrs to dhe exreme cold,or urge us not to or-der so its drivers would be safer. | Kathlen Naday | 2021 | China Weekly2021，，2： | 0 |
| 14 | Transmission of severe acute respiratory syndrome coronavirus 2 via fecal-oral:Current knowledge显示文摘The pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has resulted in more than 93 million cases and 2 million deaths in the world.SARS-CoV-2 respiratory tract infection and its main clinical manifestations such as cough and shortness of breath are well known to the scientific community.However,a growing number of studies have reported SARS-CoV-2-related gastrointestinal involvement based on clinical manifestations,such as diarrhea,nausea,vomiting,and abdominal pain as well as on the pathophysiological mechanisms associated with coronavirus disease 2019.Furthermore,current evidence suggests SARS-CoV-2 transmission via the fecal-oral route and aerosol dissemination.Moreover,studies have shown a high risk of contamination through hospital surfaces and personal fomites.Indeed,viable SARS-CoV-2 specimens can be obtained from aerosols,which raises the possibility of transmission through aerosolized viral particles from feces.Therefore,the infection by SARS-CoV-2 via fecal-oral route or aerosolized particles should beconsidered.In addition,a possible viral spread to sources of drinking water,sewage,and rivers as well as the possible risk of viral transmission in shared toilets become a major public health concern,especially in the least developed countries.Since authors have emphasized the presence of viral RNA and even viable SARS-CoV-2 in human feces,studies on the possible fecal-oral coronavirus disease 2019 transmission become essential to understand better the dynamics of its transmission and,then,to reinforce preventive measures against this infection,leading to a more satisfactory control of the incidence of the infection. | Filipe Antônio França da Silva Breno Bittencourt de Brito Maria Luísa Cordeiro Santos Hanna Santos Marques Ronaldo Teixeira da Silva Júnior Lorena Sousa de Carvalho Samuel de Sousa Cruz Gabriel Reis Rocha Gabriel Lima Correa Santos Kathlen Coutinho de Souza Rebeca Gabrielle Almeida Maciel Daiana Silva Lopes Natália Oliveira e Silva Márcio Vasconcelos Oliveira Fabrício Freire de Melo | 2021 | World Journal of Clinical Cases2021，9，28： | 0 |
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