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| 1 | Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients. | Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder | 2009 | World Journal of Gastroenterology2009，15，9： | 6 |
| 2 | Preparation of chitosan self-aggregates as a gene delivery system 显示文摘 | Lee KY Kwon IC Kim YH | 1998 | J Controlled Release1998，51，23： | 2 |
| 3 | Actin cytoskeletal architecture regulates nitric oxide-induced apoptosis, dedifferentiation, and cyclooxygenase-2 expression in articular chondrocytes via mitogen-activated protein kinase and protein kinase C pathways 显示文摘 | Kim SJ Hwang SG Kim IC | 2003 | J Biol Chem2003，278，42： | 1 |
| 4 | Tumor targetability and antitumot Effect of docetaxel-loaded hydrophobically modified glycol chitosan nanoparticles显示文摘 | Hwang HY Kim IS Kwon IC | 2008 | J Control Release2008，128，1： | 1 |
| 5 | Anti-inflammatory functions of purpurogallin in LPS-activated human endothelial cells显示文摘 | Kim TH Ku SK Lee IC | | 0，，03： | 1 |
| 6 | A genetic algorithm with a mixed region search for the asymmetric traveling salesman problem 显示文摘 | CHOI IC KIM SI KIM HS | 2003 | Computers and Operations Research ( S0305 - 0548 )2003，30，5： | 1 |
| 7 | Delayed encephalopathy of acute carbon monoxide intoxication:diffusivity of cerebral white matter lesions显示文摘 | Kim JH Chang KH Song IC | 2003 | Am J Neuroradiol2003，24，： | 1 |
| 8 | Direct writing of copper conductive patterns by ink-iet printing 显示文摘 | PARK B IC KIM D JEONG S | 2007 | Thin Solid Films2007，515，19： | 1 |
| 9 | Suppressive mechanism of salmosin,a novel disintegrin in B16 melanoma cell metastasis显示文摘 | Kang IC Kim DS Jang Y | 2000 | Biochem Biophys Res Commun2000，275，1： | 1 |
| 10 | Comparison of autologous serum and umbilical cord serum eye drops for dry eye syndrome显示文摘 | Yoon KC Heo H Ira SK You IC Kim YH Park YG | 2007 | Ant J Ophthalmol2007，144，1： | 1 |
| 11 | Delayed encephalopathy of acute car- bonmonoxide intoxication: diffusivity of cerebral white matter lesions 显示文摘 | Kim JH Chang KH Song IC | 2003 | Am JNeuroradi012003，24，： | 1 |
| 12 | Brain abscess and necrotic or cystic brain tumor:discrimination with signal intensity on diffusion-weighted MR imaging显示文摘 | Kim YJ Chang KH Song IC | 1998 | AJR1998，171，6： | 1 |
| 13 | Pr epa r a t ion andcharacterization of self-assembled nanoparticles of heparindeoxycholicacid conjugates显示文摘 | Pa rk K Kim K Kwon IC e t al | 2004 | Langmuir2004，20，11： | 1 |
| 14 | Delayed encephalopathy of acute carbon monoxide intoxication:diffasivity of cerebral white matter lesion显示文摘 | Kim J H Chang K H Song IC | 2007 | Am J Neuron adiol2007，24，： | 1 |
| 15 | Tumor targetability and antitumor effect of docetaxel loaded hydrophobically modified glycol chitosan nanoparticles显示文摘 | Hwang HY Kim IS Kwon IC | 2008 | J Control Release2008，128，1： | 1 |
| 16 | Tumor targetability and antitumor effect of docetaxel-loaded hydrophobically modified glycol chitosan nanoparticles显示文摘 | Hwang HY Kim IS Kwon IC | 2008 | J Control Release2008，128，1： | 1 |
| 17 | In vivo gene transfer to the mouse nasal cavity mucosa using astable cationic lipid emulsion 显示文摘 | Kim TW Chung H Kwon IC | 2000 | Mol Cells2000，10，2： | 1 |
| 18 | Preparation of chitosan self-aggregates as a gene delivery system 显示文摘 | Lee KY Kwon IC Kim YH | 1998 | J Control Release1998，51，23： | 1 |
| 19 | In vivo single-voxel proton MR spectroscopy in intraeranial cystic masses 显示文摘 | Chang KH Song IC Kim SH | 1998 | AJNR1998，19，2： | 1 |
| 20 | Endocrine disrupting chemicals (bisphenol A,4-nonylphenol,4-tert-octylphenol)modulate expression of two distinct cytochrome P450 aromatase genes differently in gender types of the hermaphroditic fish Rivulus marmoratus显示文摘 | LEE YM SEO JS KIM IC | 2006 | Bioehem Biophys Res Commun2006，345，2： | 1 |
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