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| 1 | Colonoscopic yield of colorectal neoplasia in daily clinical practice显示文摘AIM:To assess the prevalence and location of ad-vanced neoplasia in patients undergoing colonoscopy,and to compare the yield per indication.METHODS:In a multicenter colonoscopy survey (n = 18 hospitals) in the Amsterdam area (Northern Holland),data of all colonoscopies performed during a three month period in 2005 were analyzed. The location and the histological features of all colonic neoplasia were recorded. The prevalence and the distribution ofadvanced colorectal neoplasia and differences in yield between indication clusters were evaluated. Advanced neoplasm was defi ned as adenoma > 10 mm in size,with > 25% villous features or with high-grade dyspla-sia or cancer.RESULTS:A total of 4623 eligible patients underwent a total colonoscopy. The prevalence of advanced neo-plasia was 13%,with 281 (6%) adenocarcinomas and 342 (7%) advanced adenomas. Sixty-seven percent and 33% of advanced neoplasia were located in the distal and proximal colon,respectively. Of all patients with right-sided advanced neoplasia (n = 228),51% had a normal distal colon,whereas 27% had a syn-chronous distal adenoma. Ten percent of all colono-scopies were performed in asymptomatic patients,7% of whom had advanced neoplasia. In the respective procedure indication clusters,the prevalence of right-sided advanced neoplasia ranged from 11%-57%. CONCLUSION:One out of every 7-8 colonoscopies yielded an advanced colorectal neoplasm. Colonoscopy is warranted for the evaluation of both symptomatic and asymptomatic patients. | Jochim S Terhaar sive Droste Mike E Craanen Rene WM van der Hulst Joep F Bartelsman Dick P Bezemer Kim R Cappendijk Gerrit A Meijer Linde M Morsink Pleun Snel Hans ARE Tuynman Roy LJ van Wanrooy Eric IC Wesdorp Chris JJ Mulder | 2009 | World Journal of Gastroenterology2009,15,9: | 6 |
| 2 | Glucocorticoids upregulate transepithelial electrical resistance and expression of tight junction-related protein in human trabecular meshwork cells显示文摘 | ZHUO Ye-hong, HUANG Ya-lin, WEI Yan-tao, LING Yun-lan, LIN Ming-kai and GE Jian Key Laboratory of Ophthalmology, Ministry of Education Zhongshan Ophtha lm ic Center , Sun Yat-sen University, Guangzhou 510060, China | 2005 | Chinese Medical Journal2005,,20: | 4 |
| 3 | 晋商驼道(二)显示文摘中国的茶叶、丝绸、瓷器、桐油、竹制品产于长江以南地区,金属器物、工艺品、乐器、粮食、布匹、棉花、颜料、盐、糖和食油产于长城以南地区;而长城以北地区以及蒙古、俄罗斯、朝鲜、哈萨克斯坦、吉尔吉斯斯坦、 | 郎加明 本刊资料 IC | 2013 | 新晋商2013,,7: | 3 |
| 4 | 毫米波E面电路双工器的计算机辅助设计显示文摘介绍一种毫米波E面电路双工器的简化CAD方法,包括E-T分支的等效电路,双工器散射矩阵的分析和优化.经过在V波段的实测,表明该方法的设计结果与设计指标是相吻合的. | 刘宏伟 Hunt.,IC | 1994 | 红外与毫米波学报1994,13,4: | 3 |
| 5 | 华为的管理为什么会成功?显示文摘任正非不是照搬IBM,而是让IBM帮助华为培养专家,再依靠自己的专家建立自己的管理体系。大讲特讲追求和境界的,但同时又最懂得人内心中现实的一面。华为激发了那么一大群天之骄子内心的自豪感与事业心,也让他们通过劳动获得了经济上进而是人格上的独立。 | 白刚 东方IC | 2017 | 企业观察家2017,0,1: | 3 |
| 6 | 创意如何成为产业?显示文摘创意产业(Creatlve Industries)的产生和兴起,跨越了以往文化与工业之间鲜明的壁垒。在法兰克福学派那里,“文化工业”是适合大众消费的单文化生产,基于古典理念中“艺术批判而独立”的立场,该学派对文化产业的过度商业化与技术化持否定态度。他们认为,“文化工业”是凭借现代科技手段大规模地复制、传播商品化了的, | 李亚夫 孙萍 IC | 2005 | 21世纪商业评论2005,,9: | 3 |
| 7 | Endoscopic management of polypoid early colon cancer显示文摘 | Williams CB Saunders BP Tallot IC | | World Journal of Surgery0,,: | 3 |
| 8 | 微商:争议中生存的“关系生意”显示文摘微商:争议中生存的'关系生意'和PC端的电子商务不同,在移动互联网时代,微商崛起的速度让人吃惊。以PC为主要发展平台的淘宝用了10年的时间,才发展了不到1000万个卖家;微商仅仅用了一年,就有了超过1000万的卖家,许多草根也纷纷投入其中。时下,如果你用百度搜索'中国首富',关于马云的简介就会直接被放在搜索内容第一的位置。2014年下半年。 | 李振山 东方IC CFP | 2015 | 金桥2015,,Z1: | 2 |
| 9 | 传统文化孕育创业富矿显示文摘有人开科技公司,有人玩电商,有人回乡种树搞养殖……如今,越来越多的90后不属于走"奔走求职"的道路,而选择加入创业大军。这其中,有一些90后显得特立独行。他们心灵手巧、善于观察,将传承传统文化融入创业思想,开拓出一条与众不同的创业之路。 | 馮璐 東方 IC CFP 匯圖 昵圖 李元 | 2016 | 金桥2016,0,6: | 2 |
| 10 | Preparation of chitosan self-aggregates as a gene delivery system 显示文摘 | Lee KY Kwon IC Kim YH | 1998 | J Controlled Release1998,51,23: | 2 |
| 11 | Gender Differences in Acute Cadmium-Induced Systemic Inflammation in Rats显示文摘Objective To examine the presence of gender difierences in pro-inflammatory potential of cadmium in rats by comparing systemic inflammatory response to acute cadmium intoxication in animals of the two sexes.Methods Basic aspects of this response were evaluated,including plasma levels of inflammatory cytokines tumor necrosis factor(TNF)and interleukin-6(IL-6)and of major rat acute phase protein alpha 2-macroglobulin(alpha2-M),as soluble indicators of inflammation, and the number and activity of peripheral blood leukocytes.as cellular indicators of inflammation.Results Differential increases of IL-6 and alpha 2-M(higher in males than in females)in peripheral blood cell counts and types(leukocytosis and shift in the ratio of granulocytes to lymphocytes more pronounced in males vs females) and in levels of neutrophil priming (higher in males vs females)were noted.Conclusion The data document a more intense inflammatory response to cadmium administration in males The sex difierences in inflammatory effects of cadmium might be taken into consideration in studying the toxicity of this heavy metal. | MILENA KATARANOVSKI SRDJA JANKOVIC DRAGAN KATARANOVSKI JELENA STOIC DESA BOGOJEVIC | 2009 | Biomedical and Environmental Sciences2009,22,1: | 2 |
| 12 | 创新2.0时代下的“互联网+”显示文摘上升为国家战略的'互联网+'不仅仅是互联网移动了、泛在了、应用于传统行业了,更会同无所不在的计算、数据、知识,造就了无所不在的创新,推动了知识社会以用户创新、开放创新、大众创新、协同创新为特点的创新2.0,改变了我们的生产、工作、生活方式,也引领了创新驱动发展的'新常态'。 | 方圆 东方IC CFP | 2015 | 金桥2015,,6: | 2 |
| 13 | Actin cytoskeletal architecture regulates nitric oxide-induced apoptosis, dedifferentiation, and cyclooxygenase-2 expression in articular chondrocytes via mitogen-activated protein kinase and protein kinase C pathways 显示文摘 | Kim SJ Hwang SG Kim IC | 2003 | J Biol Chem2003,278,42: | 1 |
| 14 | ABCA1 and ABCG1 synergize to mediate cholesterol export to apoA-1 显示文摘 | Gelissen IC Harris M Rye KA | 2006 | Arterioscler Thromb Vasc Biol2006,26,3: | 1 |
| 15 | Estrogenreceptor status and outcomes of modem chemotherapy for patients with node-positive breast cancer 显示文摘 | Berry DA Cirrincione C Henderson IC | 2006 | JAMA2006,295,14: | 1 |
| 16 | Linking cardiovascular theory to practice in an undergraduate medical curriculum显示文摘 | Hudson JN Buckley P MeMillen IC | 2001 | Adv physiol Educ2001,25,12: | 1 |
| 17 | Protein kinase B/Akt activity is involved in renal TGF-β1 driven epithelialmesenchymal transition in vitro and in vivo显示文摘 | KATTLA J J CAREW R M HELJ IC M | 2008 | Am J Physiol Renal Physiol2008,295,1: | 1 |
| 18 | Erythropoietins: a common mechanism of action显示文摘 | Elliott S Pham E Macdougall IC | 2008 | Exp Hematol2008,36,12: | 1 |
| 19 | Functional assays testing pathogenicity of 14 cystathionine- beta synthase mutations 显示文摘 | Rurreizt IC Asteggiano M Cozar | 2006 | Hum Mutat2006,27,3: | 1 |
| 20 | Diotortion product otoacoustie emission and sensorineural hearing loss显示文摘 | Moulin A Bera IC | 1994 | Audiology1994,33,2: | 1 |