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| 1 | 从远程学习到电子学习再到移动学习显示文摘 | 丁兴富 Keegan,D | 2000 | 开放教育研究2000，6，5： | 129 |
| 2 | A comprehensive review on recent progress in aluminum-air batteries显示文摘The aluminum-air battery is considered to be an attractive candidate as a power source for electric vehicles(EVs) because of its high theoretical energy density(8100 Wh kg^(-1)), which is significantly greater than that of the state-of-the-art lithium-ion batteries(LIBs). However,some technical and scientific problems preventing the large-scale development of Al-air batteries have not yet to be resolved. In this review, we present the fundamentals, challenges and the recent advances in Al-air battery technology from aluminum anode, air cathode and electrocatalysts to electrolytes and inhibitors. Firstly, the alloying of aluminum with transition metal elements is reviewed and shown to reduce the selfcorrosion of Al and improve battery performance. Additionally for the cathode, extensive studies of electrocatalytic materials for oxygen reduction/evolution including Pt and Pt alloys, nonprecious metal catalysts, and carbonaceous materials at the air cathode are highlighted.Moreover, for the electrolyte, the application of aqueous and nonaqueous electrolytes in Al-air batteries are discussed. Meanwhile, the addition of inhibitors to the electrolyte to enhance electrochemical performance is also explored. Finally, the challenges and future research directions are proposed for the further development of Al-air batteries. | Yisi Liu Qian Sun Wenzhang Li Keegan R.Adair Jie Li Xueliang Sun | 2017 | Green Energy & Environment2017，2，3： | 13 |
| 3 | 创新性淀粉节约方案——通过纤维中的淀粉回收提高纸板生产的可持续性显示文摘用于制造再生纸和纸板的纤维原材料中含有大量淀粉。由于微生物的活性,使用回收纤维的纸浆中的过程水通常含有大量淀粉水解酶。这经常导致大多数淀粉在回收纤维进入造纸机之前水解掉,因此潜在地增加了废水中的化学需氧量COD、pH值降低,并且由于碳酸钙溶解使得电导率变高。在本文中,我们提出了一种新颖的提高淀粉再利用及包装纸强度的理念。该理念包括使用特定的淀粉酶抑制剂,防止回收纤维和损纸中的淀粉水解,以及全新的助留系统用以提高淀粉在最终产品中的保留率。淀粉酶抑制剂自身或与杀菌剂组合能够有效防止淀粉水解。这在实验室研究和工厂试验均有所体现。此外,留着率和强度实验表明混凝剂、微聚物和新的高分子聚合物的组合提高了淀粉的留着率和滤水性。 | Jaakko Ekman Matti Hietaniemi Marko Kolari Mark Nelson Ken Keegan | 2018 | 中华纸业2018，39，2： | 7 |
| 4 | Final anatomic and visual outcomes appear independent of duration of silicone oil intraocular tamponade in complex retinal detachment surgery显示文摘AIM: To report anatomic and visual outcomes following silicone oil removal in a cohort of patients with complex retinal detachment, to determine association between duration of tamponade and outcomes and to compare patients with oil removed and those with oil in situ in terms of demographic, surgical and visual factors. METHODS: We reported a four years retrospective case series of 143 patients with complex retinal detachments who underwent intraocular silicone oil tamponade. Analysis between anatomic and visual outcomes, baseline demographics, duration of tamponade and number of surgical procedures were carried out using Fisher's exact test and unpaired two-tailed t-test. RESULTS: One hundred and six patients(76.2%) had undergone silicone oil removal at the time of review with 96 patients(90.6%) showing retinal reattachment following oil removal. Duration of tamponade was not associated with final reattachment rate or with a deterioration in best corrected visual acuity(BCVA). Patients with oil removed had a significantly better baseline and final BCVA compared to those under oil tamponade(P=0.0001, <0.0001 respectively). CONCLUSION: Anatomic and visual outcomes in this cohort are in keeping with those reported in the literature. Favorable outcomes were seen with oil removal but duration of oil tamponade does not affect final attachment rate with modern surgical techniques and should be managed on a case by case basis. | Maedbh Rhatigan Elizabeth Mc Elnea Patrick Murtagh Kirk Stephenson Elaine Harris Paul Connell David Keegan | 2018 | International Journal of Ophthalmology(English edition)2018，11，1： | 7 |
| 5 | Costimulation of resting B lymphocytes alters the IL-4-activated IRS2 signaling pathway in a STAT6 independent manner: implications for cell survival and proliferation显示文摘IL-4 is an important B cell survival and growth factor. IL-4 induced the tyrosine phosphorylation of IRS2 in resting B lymphocytes and in LPS- or CD40L-activated blasts. Phosphorylated IRS2 coprecipitated with the p85 subunit of PI 3’ kinase in both resting and activated cells. By contrast, association of phosphorylated IRS2 with GRB2 was not detected in resting B cells after IL-4 treatment although both proteins were expressed. However, IL-4 induced association of IRS2 with GRB2 in B cell blasts. The pattern of IL-4- induced recruitment of p85 and GRB2 to IRS2 observed in B cells derived from STAT6 null mice was identical to that observed for normal mice. While IL-4 alone does not induce activation of MEK, a MEKI inhibitor suppressed the IL-4-induced proliferative response of LPS-activated B cell blasts. These results demonstrate that costimulation of splenic B cells alters IL-4-induced signal transduction independent of STAT6 leading to proliferation. Furthermore, proliferation induced by IL-4 in LPS-activated blasts is dependent upon the MAP kinase pathway. | ZAMORANO JOSE,Unidad de Investigacion, Hospital San Pedro de Alcantara, Avda Millan Astray, 10003 Caceres ANN E KELLY, JONATHAN AUSTRIAN, HELEN Y WANG, ACHSAH D KEEGAN (Department of Immunology, Jerome Holland Labs, American Red Cross, Rockville, MD, USA | 2001 | Cell Research2001，11，1： | 4 |
| 6 | Paediatric retinal detachment:aetiology,characteristics and outcomes显示文摘AIM: To provide contemporary data on the aetiology, clinical features and outcomes of paediatric retinal detachment.METHODS: A retrospective review of all those under 16 y who underwent surgical repair for retinal detachment at a single centre between the years 2008 and 2015 inclusive was performed. In each case the cause of retinal detachment, the type of detachment, the presence or absence of macular involvement, the number and form of reparative surgeries undertaken, and the surgical outcome achieved was recorded.RESULTS: Twenty-eight eyes of 24 patients, 15(62.5%) of whom were male and 9(37.5%) of whom were female, their mean age being 11.6 y and range 2-16y developed retinal detachment over the eight year period studied. Trauma featured in the development of retinal detachment in 14(50.0%) cases. Retinal detachment was associated with other ocular and/or systemic conditions in 11(39.3%) cases. A mean of 3.0 procedures with a range of 1-9 procedures per patient were undertaken in the management of retinal detachment. Complex vitrectomy combined with scleral buckling or complex vitrectomy alone were those most frequently performed. Mean postoperative visual acuity was 1.2 log MAR with range 0.0-3.0 log MAR. In 22 of 26(84.6%) cases which underwent surgical repair the retina was attached at last follow-up.CONCLUSION: Aggressive management of paediatric retinal detachment including re-operation increases the likelihood of anatomical success. In cases where the retinal detachment can be repaired by an external approach alone there is a more favourable visual outcome. | Elizabeth McElnea Kirk Stephenson Sarah Gilmore Michael O'Keefe David Keegan | 2018 | International Journal of Ophthalmology(English edition)2018，11，2： | 2 |
| 7 | Low ectopic pregnancy rates after in vitro fertilizat ion:do practice habits matter显示文摘 | Keegan DA Morelli SS Noyes N | 2007 | Fert il Steril2007，88，3： | 1 |
| 8 | IL-4 regulates growth and differentiation by distinct mechanisms显示文摘 | Keegan AD Ryan JJ Paul WE | 1996 | The Immunologist1996，4，： | 1 |
| 9 | Cell culture- Taqman PCR assay for evaluation of Cryptosporidium parvum disinfection显示文摘 | Keegan A R Fanok S Monis P T | 2003 | Appl Environ Mierobiol2003，69，5： | 1 |
| 10 | Cross validation of the Montreal Cognitive Assessment in community dwelling older adults residing in the southeastern US显示文摘 | Luis CA Keegan AP Mullan M | 2009 | Int J Geriatr Psychiatry2009，24，2： | 1 |
| 11 | Anton' s syndrome due to cerebrovascular disease : a case report 显示文摘 | Maddula M Lutton S Keegan B | 2009 | J Med Case Reports2009，3，： | 1 |
| 12 | THE IL-4 RECEPTOR: Signaling Mechanisms and Biologic Functions显示文摘 | Keats Nelms Achsah D. Keegan José Zamorano John J. Ryan William E. Paul | 1999 | Annual Review of Immunology1999，，： | 1 |
| 13 | Retinoic acid signaling restricts the cardiac progenitor pool 显示文摘 | KEEGAN B R FELDMAN J L BEGEMANN G | 2005 | Science2005，307，5707： | 1 |
| 14 | Effects of diabetes and treatment with the antioxidant α-lipoic acid on endotheli-al and neurogenic responses of corpus cavernosum in rats显示文摘 | Keegan A Cotter M A Cameron N E | 1999 | Diabetologia1999，42，： | 1 |
| 15 | Comparison of DNA extraction from cervical cells collected in PreservCyt solution for the amplification of Chlamydia trachomatis显示文摘 | Keegan H Boland C Malkin A | 2005 | Cytopathology2005，16，2： | 1 |
| 16 | Environmental temperature controls Cryptosporidium oocyst meta- bolic rate and associated retention of infectivity显示文摘 | King B J Keegan A R Monis P T | 2005 | Ap- pl Environ Microbiol2005，71，7： | 1 |
| 17 | 'Pediatric blaschkitis': expanding the spectrum of childhood acquired Blaschko -linear dennatoses显示文摘 | Keegan BR Kamino H Fangman W | 2007 | Pediatr Dermatol2007，24，： | 1 |
| 18 | Necessity of hippocampal neurogenesis for the therapeutic action of antidepressants in adult nonhuman primates显示文摘 | Perera TD Dwork AJ Keegan KA | 2011 | PLoS One2011，6，17： | 1 |
| 19 | The cause of dissociated motor loss in upper extremity with cervical spondylosis : a ease report 显示文摘 | Keegan JJ | 1965 | J Neurosueg1965，23，5： | 1 |
| 20 | The burden of liver cancer in asians and pacific islanders in the greater san Francisco bay area, 1900 through 2004 显示文摘 | Chang ET Keegan TH Gomez SL | 2007 | Cancer2007，109，10： | 1 |
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