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	题名	作者	年代	出处	被引量
1	Serum Neutrophil Gelatinase-associated Lipocalin(NGAL)Is Elevated in Patients with Asthma and Airway Obstruction显示文摘Neutrophilic airway inflammation is one of the features of severe asthma.Neutrophil gelatinase-associated lipocalin(NGAL),or lipocalin-2,is a glycoprotein associated with neutrophilic inflammation and can be detected in blood.Recently,blood NGAL levels have been reported to be elevated in chronic obstructive pulmonary disease.However,the clinical significance of serum NGAL levels in patients with asthma has not been elucidated.The aim of this study was to explore the association between serum NGAL level and clinical parameters in patients with asthma.Sixty.one non-smoking people with stable asthma were enrolled in this study.All patients underwent blood ollction and pulmonary function tests.The associations between serum NGAL levels and clinical parameters were analyzed retrospectively.Serum NGAL levels in patients with asthma and obstructive ventilatory defect were higher than those in patients with asthma without obstructive ventilatory defect(76.4±51.4 ng/mL vs.39.3±27.4 ng/mL,P=0.0019).Serum NGAL levels were correlated with forced expired flow at 50%of vital capacity%predicted and forced expired flow at 75%of vital capacity%predicted(r=-0.3373,P=0.0078 and r=0.2900,P=0.0234,respectively).Results of a multiple regression analysis demonstrated that serum NGAL level was independently associated with obstructive ventilatory defect.Serum NGAL levels were elevated in patients with asthma and obstructive ventilatory defect.NGAL may be involved in airway remodeling possibly mediated by neutrophilic inflammation in asthma.	Junichiro Kawagoe Yuta Kono Yuki Togashi Mayuko Ishiwari Kazutoshi Toriyama Chika Yajima Hideaki Nakayama Satoshi Kasagi Shinji Abe Yasuhiro Setoguchi	2021	Current Medical Science2021，41，2：	5
2	Differential regulation of corticotropin-releasing factor receptor type 1 (CRF1 receptor ) mRNA via protein kinase A and mitogen activated protein kinase pathways in rat anterior pituitary cells 显示文摘	Moriyama T Kageyama K Kasagi Y	2005	Mol Cell Endocrinol2005，243，112：	1
3	Forced convective boiling heat transfer in microtubes at low mass and heat fluxes显示文摘	YEN T KASAGI N SUZUKI Y	2003	International Journal of Multiphase Flow2003，29，12：	1
4	Does seed production of spring ephemerals decrease when spring comes early?显示文摘	Gaku KUDO Yoko NISHIKAWA Tetsuya KASAGI Shoji KOSUGE	2004	Ecological Research2004，，2：	1
5	PD-1 and autoimmunity显示文摘	Kasagi S Kawano S Kumagai S	2011	Crit Rev Immunol2011，31，4：	1
6	lctal dipole source analysis based on a realistic scalp-skull-brain head model in localizing the epileptogenic zone显示文摘	Mine S lwasa H Kasagi Y	2005	Neurosci Res2005，51，4：	1
7	Renal needle biopsy along the retrograde puncture line of the renal calyx: a new promisising technique显示文摘	Mimata H Kasagi Y Nasu N	1998	UrolInt1998，60，3：	1
8	Measurement of liquid film thickness in a micro parallel channel with interferometer and laser focusdisplacement meter显示文摘	Han Y Shikazono N Kasagi N	2011	International Journal of Multiphase Flow2011，37，1：	1
9	Apoptotic cell deathin human gastric carcinoma: analysis by terminal deoxynucleotidyl transferase- mediated dUTP- biotin nick end labeling显示文摘	GomyoY Shirai H Tsujitani S Ito H	1994	Jpn J Cancer Res1994，85，：	1
10	Experimentalstudy of micro-scale premixed flame in quartz chan- nels 显示文摘	FAN Y SUZUKI Y KASAGI N	2009	Proceedings of the Combustion Institute2009，32，2：	1
11	Quenching mechanism study of oscil- lating flame in micro channels using phase-locked OH-PLIF显示文摘	Fan Y Suzuki Y Kasagi N	2011	Proceedings of the Combustion Institute2011，33，2：	1
12	Role of imaging studies in the diagnosis and evaluation of giant cell arteri- tis in Japanese: report of eight cases 显示文摘	Morinobu A Tsuji G Kasagi S	2011	Mod Rheuma- tol2011，21，4：	1
13	Quenching mechanism study of oscillating flame in micro chan- nels using phase-locked OH-PLIF 显示文摘	FAN Y SUZUKI Y KASAGI N	2011	Proceedings of the Combustion Institute2011，33，2：	1
14	Comparison of serum thyrotrophin concentrations determined by a third generation assay in patients with various types of overt and subclinical thyrotoxicosis 显示文摘	Kasagi K Kousaka T Misaki T	1999	Clin Endocrinol (Oxf)1999，50，2：	1
15	Numerical simulation of gas–liquid two-phase flow and convective heat transfer in a micro tube显示文摘	Koji Fukagata Nobuhide Kasagi Poychat Ua-arayaporn Takehiro Himeno	2006	International Journal of Heat and Fluid Flow2006，，1：	1
16	Apoptosis occurs more frequently in metastatic foci than in primary lesions of human colorectal cacinoma:analysis by terminal-deoxynucleotidge-transferase-mediated Dutp-biotinnick end labeling显示文摘	Tatebe S Ishida M Kasagi N	1996	Int JCanncer1996，65，2：	1
17	Ictal dipole source analysis based on a realistic scalp skull brain head model inlocalizing the epilep togenic zone显示文摘	Mine S Iwasa H Kasagi Y	2005	Neurosci Res2005，51，4：	1
18	Cystic papillary carcinoma of the thyroid gland: A new sonographic显示文摘	Hatabu H kasagi k Yamamoto K	1991	Clin Radiol1991，43，1：	1
19	Three-dimensional particle tracking velocimetry based on automated digital image processing显示文摘	NISHINO K KASAGI N HIRATA M	1989	Journal of Fluid Engineering1989，111，：	1
20	Development of a Large- Entrainment-Ratio Axisymmetric Supersonic Ejector for Micro Butane Combustor 显示文摘	Fan Y Suzuki Y Kasagi N	2006	Journal of Micromechanics and Microengineering2006，16，9：	1

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