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13篇 您的检索式:作者名="K.Choi"
    题名 作者 年代 出处 被引量
1Hyperuricemia and incident hypertension: A systematic review and meta‐analysis显示文摘Peter C.Grayson Seo YoungKim MichaelLaValley Hyon K.Choi 2010Arthritis Care Res2010,,1:4
2Intake of purine‐rich foods, protein, and dairy products and relationship to serum levels of uric acid: The Third National Health and Nutrition Examination Survey显示文摘Hyon K.Choi SiminLiu GaryCurhan 2005Arthritis & Rheumatism2005,,1:4
3Molecular and Biological Diversities of Cucumber green mottle mosaic virus from Cucurbitaceous Crops in Korea显示文摘J. Y.Yoon G. S.Choi S. K.Choi J. S.Hong J. K.Choi W.Kim G. P.Lee K. H.Ryu 2008Journal of Phytopathology (鈥?)2008,,7:1
4Randomized clinical trial comparing loop ileostomy and loop transverse colostomy for faecal diversion following total mesorectal excision显示文摘W. L.Law K. W.Chu H. K.Choi 2002Br J Surg2002,,6:1
5COX‐2 and Neurodegeneration in Parkinson’s Disease显示文摘P.TEISMANN M.VILA D.‐K.CHOI K.TIEU D. C.WU V.JACKSON‐LEWIS S.PRZEDBORSKI 2006Annals of the New York Academy of Sciences2006,,1:1
6A Framework for Stress-testing Banks' Credit Risk显示文摘Wong J K.Choi 0,,01:1
7Selective Anion Binding by a Macro-cycle with Convergent Hydrogen Bonding Functionality显示文摘K.Choi A.D.Hamilton 0,,:1
8Three‐vessel view of the fetal upper mediastinum: an easy means of detecting abnormalities of the ventricular outflow tracts and great arteries during obstetric screening显示文摘S. ‐J.Yoo Y.‐H.Lee E. S.Kim H. M.Ryu M. Y.Kim H.‐K.Choi K. S.Cho A.Kim 2002Ultrasound Obstet Gynecol2002,,3:1
9COX‐2 and Neurodegeneration in Parkinson’s Disease显示文摘P.TEISMANN M.VILA D.‐K.CHOI K.TIEU D. C.WU V.JACKSON‐LEWIS S.PRZEDBORSKI 2006Annals of the New York Academy of Sciences2006,,1:1
10Chronic activation of 4-1BB signaling induces granuloma development in tumor-draining lymph nodes that is detrimental to subsequent CD8^(+)T cell responses显示文摘The antitumor capabilities of agonistic anti-4-1BB mAbs have made them an attractive target for tumor immunotherapy.However,the adverse side effects associated with agonist antibodies have hindered their clinical development.Here,we aimed to study the immune-related adverse events of repeated doses and long-term use of agonistic anti-4-1BB mAbs.We show that chronic activation of 4-1BB signals induced the accumulation of IFN-γ-producing PD-1^(+)CD8^(+)T cells in the secondary lymphoid organs of tumor-bearing mice by increasing the number of dividing CD8^(+)T cells,which was beneficial for suppressing tumor growth in the early phase of anti-4-1BB induction.However,repeated exposure to anti-4-1BB mAbs led to granuloma development in tumor-draining lymph nodes(TDLNs)of mice due to recruitment and accumulation of macrophages via the CD8^(+)T cell-IFN-γaxis.This was accompanied by excessive lymph node swelling,which impaired the sequential activation of CD8^(+)T cells.Our data provide insights into the immune-related adverse events of long-term agonist 4-1BB antibody dosing,which should be considered during the clinical development of immunomodulating therapy.Seon-Hee Kim Rohit Singh Chungyong Han Eunjung Cho Yu I.Kim Don G.Lee Young H.Kim Sang Soo Kim Dong Hoon Shin Hye Jin You Hyeon-Woo Lee Byoung S.Kwon Beom K.Choi 2021Cellular & Molecular Immunology2021,18,8:0
11This work was supported in part by US Department of Energy Los Alamos National Laboratory contract 47145 and UT-Battelle LLC contract 4000159447 program manager Laura Biven.显示文摘There is a growing trend of applying machine learning methods to medical datasets in order to predict patients’future status.Although some of these methods achieve high performance,challenges still exist in comparing and evaluating different models through their interpretable information.Such analytics can help clinicians improve evidence-based medical decision making.In this work,we develop a visual analytics system that compares multiple models’prediction criteria and evaluates their consistency.With our system,users can generate knowledge on different models’inner criteria and how confidently we can rely on each model’s prediction for a certain patient.Through a case study of a publicly available clinical dataset,we demonstrate the effectiveness of our visual analytics system to assist clinicians and researchers in comparing and quantitatively evaluating different machine learning methods.Yiran Li Takanori Fujiwara Yong K.Choi Katherine K.Kim Kwan-Liu Ma 2020Visual Informatics2020,4,2:0
124-1BB-4-1BBL cis-interaction contributes to the survival of selfreactive CD8^(+)T cell显示文摘4-1BB is an inducible receptor expressed on activated T cells,while its ligand,4-1BBL,is mainly expressed in antigen-presenting cells and macrophages[1,2].To the best of our knowledge,ligandmediated transactivation of 4-1BB is responsible for the survival and immune effector functions of T cells.Eunjung Cho Rohit Singh Chungyong Han Seon-Hee Kim Kwang H.Kim Bo-Mi Park Dong Hoon Shin Seongeun Han Young H.Kim Byoung S.Kwon Ki Taek Nam Beom K.Choi 2023Cellular & Molecular Immunology2023,20,9:0
13“罗马法·中国法与民法法典化”国际研讨会会议综述(英文)显示文摘I.THE BACKGROUND Almost twenty years ago,Jiang Ping observed that along with the development of reforms for a market economy with socialist characteristics,the legal system and notions in China were undergoing relevant changes as well.The eminent jurist stressed that,in a sense。Samuel K.Choi 2014China Legal Science2014,2,6:0
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