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| 1 | Ultrafast optical nonlinearity of blue-emitting perovskite nanocrystals显示文摘Perovskite nanocrystals(NCs) have strong nonlinear optical responses with a number of potential applications,ranging from upconverted blue-lasing to the tagging of specific cellular components in multicolor fluorescence microscopy. Here, we determine the one-photon linear absorption cross section of two kinds of blue-emitting perovskite NCs, i.e., CsPbCl_3 and CsPb(Cl_(0.53)Br_(0.47))_3, by utilizing femtosecond transient absorption spectroscopy. The wavelength-dependent nonlinear refraction and two-photon absorption have been measured at wavelengths from 620 to 720 nm by performing Z-scan measurements. The nonlinear optical responses of CsPb(Cl_(0.53)Br_(0.47))_3 are much more pronounced than those of CsPbCl_3 due to the larger structural destabilization of the former. | JUNZI LI CAN REN XIN QIU XIAODONG LIN RUI CHEN CHENG YIN TINGCHAO HE | 2018 | Photonics Research2018，6，6： | 3 |
| 2 | Activation of medial septum cholinergic neurons restores cognitive function in temporal lobe epilepsy显示文摘Cognitive impairment is the most common complication in patients with temporal lobe epilepsy with hippocampal scle rosis.There is no effective treatment for cognitive impairment.Medial septum cholinergic neurons have been reported to be a potential target for controlling epileptic seizures in tempo ral lobe epile psy.However,their role in the cognitive impairment of temporal lobe epilepsy remains unclear.In this study,we found that patients with temporal lobe epile psy with hippocampal sclerosis had a low memory quotient and severe impairment in verbal memory,but had no impairment in nonverbal memory.The cognitive impairment was slightly correlated with reduced medial septum volume and medial septum-hippocampus tra cts measured by diffusion tensor imaging.In a mouse model of chronic temporal lobe epilepsy induced by kainic acid,the number of medial septum choline rgic neurons was reduced and acetylcholine release was reduced in the hippocampus.Furthermore,selective apoptosis of medial septum cholinergic neurons mimicked the cognitive deficits in epileptic mice,and activation of medial septum cholinergic neurons enhanced hippocampal acetylcholine release and restored cognitive function in both kainic acid-and kindling-induced epile psy models.These res ults suggest that activation of medial septum cholinergic neurons reduces cognitive deficits in temporal lobe epilepsy by increasing acetylcholine release via projections to the hippocampus. | Junzi Chen Yu Wang Cong Chen Qingyang Zhang Shuang Wang Yi Wang Jiajia Fang Ying Wang | 2023 | Neural Regeneration Research2023，18，11： | 1 |
| 3 | Linear and nonlinear photophysical properties of ZnSe/CdS/ZnS core/shell/shell typeⅡnanocrystals显示文摘In this work,one kind of typeⅡZnSe/CdS/ZnS core/shell/shell nanocrystals(NCs)is synthesized,and their linear and nonlinear photophysical properties are investigated.Through measurements of the temperaturedependent photoluminescence spectra of NCs,their excitonic properties,including the coefficient of the bandgap change,coupling strength of the exciton acoustic phonons,exciton longitudinal optical(LO)phonons,and LO–phonon energy are revealed.Femtosecond transient absorption spectroscopy was employed to obtain insight into ultrafast processes occurring at the interface of ZnSe and CdS,such as those involving the injection of photoinduced electrons into the CdS shell,interfacial state bleaching,and charge separation time.At the end,their multiphoton absorption spectra were determined by using the z-scan technique,which yielded a maximum twophoton absorption cross section of 3717 GM at 820 nm and three-photon absorption cross section up to 3.9×10^-77cm^6·s^2·photon^-2at 1220 nm,respectively.The photophysical properties presented here may be important for exploiting their relevant applications in optoelectronic devices and deep-tissue bioimaging. | YANG GAO XIN QIU FULI ZHAO SHUYU XIAO JUNZI LI XIAODONG LIN RUI CHEN AND TINGCHAO HE | 2020 | Photonics Research2020，8，9： | 1 |
| 4 | Reactive glia-to-GABAergic neuron reprogramming:a“golden touch”strategy to alleviate intractable seizures显示文摘This commentary highlights a research article published recently in Cell Stem Cell“Reprogramming reactive glia into interneurons reduces chronic seizure activity in a mouse model of mesial temporal lobe epilepsy”.Generally,Lentini et al.reveal a strategy to fulfill in vivo glia-to-neuron reprogramming,which is a potential disease-modifying strategy for treatment of intractable seizures.Here,we describe exciting research advances in the treatment of intractable seizures based on this research article,summarizing its key findings,emphasizing its importance and providing further discussions.Further,issues worthy of further investigations are also postulated so that clinic translation can be better achieved. | Junzi Chen Zhongxia Li Liying Chen | 2022 | Acta Epileptologica2022，5，3： | 0 |
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