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| 1 | Complete genome analysis of Ketogulonigenium sp. WB0104显示文摘Ketogulonigenium sp. may convert L-sorbose into 2-keto-L-gulonic acid, the vitamin C precursor. The genome of Ketogulonigenium sp. WB0104 consists of a circular 2765030 bp chromo- some with 61.69% G+C content and two circular plasmids of 267968 and 242707 bp. The genome contains 2727 open reading frames (ORFs). The systems of replication, transcription, translation, carbohydrate and energy metabolism are intact, but the repair system is incomplete. About 640 predicted ORFs have been found to encode transporter pro- teins, which account for about one fourth of total predicted ORFs, noticeably higher than other docu- mented bacteria. This may be due to the fact that WB0104 adapts to soil circumstance. | YANG Fan JIA Qian XIONG Zhaohui ZHANG Xiaobing WU Hongtao ZHAO Ying YANG Jian ZHU Junping DONG Jie XUE Ying SUN Lilian SHEN Yan JIN Qi | 2006 | Chinese Science Bulletin2006，51，8： | 6 |
| 2 | Robust visual tracking based on scale invariance and deep learning显示文摘 | Nan REN Junping DU Suguo ZHU Linghui LI Dan FAN JangMyung LEE | 2017 | Frontiers of Computer Science2017，11，2： | 2 |
| 3 | Surface modification of an up-conversion luminescence material by overcoating with SiO_2 and its characterization显示文摘The surface of an up-conversion luminescence material was modified by overcoating with SiO2, which was syn- thesized from a hydrolysis progress of tetraethoxysilane (TEOS) in alkalescent condition. By analyzing the hydrolyzed mechanism of TEOS, it was found that there was not only physical adsorption but also chemical bonding between the up-conversion material and SiO2. At the same time, some adsorption bands at 1100, 475, 950, and 3500 cm?1 were found by FI-IR, which were the characteristic bands of Si?OH and Si?O?Si. By analyzing the surface elements of the coated material by XPS, it was found that its surface only included Si, O, and C elements, and not F and Y. In the picture of XRD, there was no additional peak after surface modification, suggesting that the silica shell was amorphous. The small peak at 2θ = 23° in the X-ray diffraction pattern of the coated material was caused by the amorphous SiO2 shell, and the TEM image also proved that the surface of the material was successfully modified by overcoating with SiO2. The amount of hydroxyls was then increased on the surface of the material, which made it easy to connect with other active groups. | CUI Lili LIU Jiemin FAN Huili XU Xiaowei YANG Min XIAO Junping | 2007 | Rare Metals2007，26，3： | 2 |
| 4 | Surface modification of up-conversion luminescence material Na[Y_(0.57)Yb_(0.39)Er_(0.04)]F_4 with hydrosulfide group显示文摘A new method was reported for surface modification of an up-conversion luminescence material with hydrosulfide group. The factors that may influence the surface modification,such as reaction time,amount of catalyzer and modifier,and reaction solvent,were investigated. The optimal conditions were that the reaction time,the quantity of the basic catalyzer,the quantity of modifier and the volume of reaction solvent were 40 min,1.0,1.0,and 40 mL,respectively. The results indicated that hydrosulfide group content modified on the surface of up-conversion luminescence material reached to 0.1430 mmol/g,and this modified up-conversion lumi-nescence material could be widely used in the study of structure of protein and the property of microenvironment. | Lili Cui Huili Fan Junping Xiao Xiaowei Xu Dong Su | 2008 | Journal of University of Science and Technology Beijing2008，15，5： | 2 |
| 5 | Substrate-bound structure of the E. coil multidrug resistance transporter MdfA显示文摘 | Jie Heng Yan Zhao Ming Liu Yue Liu Junping Fan Xianping Wang Yongfang Zhao Xuejun C Zhang | 2015 | Cell Research2015，25，9： | 2 |
| 6 | Detection and parameter estimation of LFM signal using integration of fractional Gaussian window transform显示文摘 | LI Jiaqiang JIN Ronghong GENG Junping FAN Yu MAO Wei | 2007 | IEICE Transactions on Communications2007，90，3： | 1 |
| 7 | Synthesis of Highly Stabilized Zirconia Sols from Zirconium n-propoxide-diglycol System显示文摘 | Junping Zhao Wenhao Fan Dong Wu | 2000 | Journal of Non-Crystalline Solids2000，261，： | 1 |
| 8 | An international Delphi consensus statement on metabolic dysfunction-associated fatty liver disease and risk of chronic kidney disease显示文摘Background:With the rising global prevalence of fatty liver disease related to metabolic dysfunction,the association of this common liver condition with chronic kidney disease(CKD)has become increasingly evident.In 2020,the more inclusive term metabolic dysfunction-associated fatty liver disease(MAFLD)was proposed to replace the term non-alcoholic fatty liver disease(NAFLD).The observed association between MAFLD and CKD and our understanding that CKD can be a consequence of underlying metabolic dysfunction support the notion that individuals with MAFLD are at higher risk of having and developing CKD compared with those without MAFLD.However,to date,there is no appropriate guidance on CKD in individuals with MAFLD.Furthermore,there has been little attention paid to the link between MAFLD and CKD in the Nephrology community.Methods and Results:Using a Delphi-based approach,a multidisciplinary panel of 50 international experts from 26 countries reached a consensus on some of the open research questions regarding the link between MAFLD and CKD.Conclusions:This Delphi-based consensus statement provided guidance on the epidemiology,mechanisms,management and treatment of MAFLD and CKD,as well as the relationship between the severity of MAFLD and risk of CKD,which establish a framework for the early prevention and management of these two common and interconnected diseases. | Dan-Qin Sun Giovanni Targher Christopher D.Byrne David C.Wheeler Vincent Wai-Sun Wong Jian-Gao Fan Herbert Tilg Wei-Jie Yuan Christoph Wanner Xin Gao Michelle T.Long Mehmet Kanbay Mindie H.Nguyen Sankar D.Navaneethan Yusuf Yilmaz Yuli Huang Rino A.Gani Pierluigi Marzuillo Jérôme Boursier Huijie Zhang Chan-Young Jung Jin Chai Luca Valenti George Papatheodoridis Giovanni Musso Yu-Jun Wong Mohamed El-Kassas Nahum Méndez-Sánchez Silvia Sookoian Michael Pavlides Ajay Duseja Adriaan G.Holleboom Junping Shi Wah-Kheong Chan Yasser Fouad Junwei Yang Sombat Treeprasertsuk Helena Cortez-Pinto Masahide Hamaguchi Manuel Romero-Gomez Mamun Al Mahtab Ponsiano Ocama Atsushi Nakajima Chunsun Dai Mohammed Eslam Lai Wei Jacob George Ming-Hua Zheng | 2023 | Hepatobiliary Surgery and Nutrition2023，12，3： | 1 |
| 9 | Transcriptome profile of Dunaliella salina in Yuncheng Salt Lake reveals salt-stress-related genes under diff erent salinity stresses显示文摘Salt stress is an abiotic stress to plants in especially saline lakes.Dunaliella,a halophilic microalga distributed throughout salt lakes and seas,can respond to different salinity stresses by regulating the expression of some genes.However,these genes and their function and biological processes involved remain unclear.Profi ling these salt-stress-related genes in a high-salt-tolerant Dunaliella species will help clarify the salt tolerance machinery of Dunaliella.Three D.salina_YC salt-stress groups were tested under low(0.51 mol/L),moderate(1.03 mol/L),and high(3.42 mol/L)NaCl concentrations and one control group under very low(0.05 mol/L)NaCl concentration and 3 transcriptome results that were deep sequenced and de novo assembled were obtained per group.Twelve high-quality RNA-seq libraries with 46585 upregulated and 47805 downregulated unigenes were found.Relative to the control,188 common differentially expressed genes(DEGs)were screened and divided into four clusters in expression pattern.Fifteen of them annotated in the significant enriched Gene Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)were validated via qPCR.Their qPCR-based relative expression patterns were similar to their RNA-seq-based patterns.Two significant DEGs,the geranylgeranyl diphosphate synthase coding gene(1876-bp cDNA)and diacylglycerol O-acyltransferase coding gene(2968-bp cDNA),were cloned and analyzed in silico.The total lipid content,superoxide dismutase specific activity,and betacarotene content of D.salina_YC increased gradually with increasing salinity.In addition,the expression of 11 validated genes involved in fatty acid biosynthesis/degradation,active oxygen or carotenoid metabolisms showed significant changes.In addition,algal photochemical efficiency was diminished with increasing salinity,as well as the expression of 4 photosynthesis-related genes.These results could help clarify the molecular mechanisms underlying D.salina responses to the Yuncheng Salt Lake environment and lay a foundation for further utilization of this algal resource. | Fan GAO Fangru NAN Jia FENG Junping LÜ Qi LIU Xudong LIU Shulian XIE | 2021 | Journal of Oceanology and Limnology2021，39，6： | 1 |
| 10 | Effective and green synthesis of methyl pyrrole-l-carboxylate with dimethyl carbonate over solid base 显示文摘 | Fan Subing Zhao Ning Li Junping | 2008 | Catal Lett2008，120，34： | 1 |
| 11 | The RhHB1/RhLOX4 module affects the dehydration tolerance of rose flowers(Rosa hybrida)by fine-tuning jasmonic acid levels显示文摘Phytohormones are key factors in plant responsiveness to abiotic and biotic stresses,and maintaining hormone homeostasis is critically important during stress responses.Cut rose(Rosa hybrida)flowers experience dehydration stress during postharvest handling,and jasmonic acid(JA)levels change as a result of this stress.However,how JA is involved in dehydration tolerance remains unclear.We investigated the functions of the JA-and dehydration-induced RhHB1 gene,which encodes a homeodomain-leucine zipper Iγ-clade transcription factor,in rose flowers.Silencing RhHB1 decreased petal dehydration tolerance and resulted in a persistent increase in JA-Ile content and reduced dehydration tolerance.An elevated JA-Ile level had a detrimental effect on rose petal dehydration tolerance.RhHB1 was shown to lower the transient induction of JA-Ile accumulation in response to dehydration.In addition to transcriptomic data,we obtained evidence that RhHB1 suppresses the expression of the lipoxygenase 4(RhLOX4)gene by directly binding to its promoter both in vivo and in vitro.We propose that increased JA-Ile levels weaken the capacity for osmotic adjustment in petal cells,resulting in reduced dehydration tolerance.In conclusion,a JA feedback loop mediated by an RhHB1/RhLOX4 regulatory module provides dehydration tolerance by fine-tuning bioactive JA levels in dehydrated flowers. | Youwei Fan Jitao Liu Jing Zou Xiangyu Zhang Liwei Jiang Kun Liu Peitao Lü Junping Gao Changqing Zhang | 2020 | Horticulture Research2020，7，1： | 1 |
| 12 | CFP1调控小鼠卵母细胞组蛋白H3K4me3修饰和发育潜质显示文摘文章简介受精过程中,合子DNA在卵母细胞中母源性因子的作用下发生重编程,促进合子基因组的重编程和转录激活,因此受精卵基因组重编程过程是表观遗传因子调控机制的理想模型,但调节机制很少被研究过。 | Chao Yu Xiaoying Fan Qian-Qian Sha Hui-Han Wang Bo-Tai Li Xing-Xing Dai Li Shen Junping Liu Lie Wang Kui Liu Fuchou Tang 范衡宇 | 2018 | 科学新闻2018，0，4： | 0 |
| 13 | Identification of novel salt stress-responsive microRNAs through sequencing and bioinformatic analysis in a unique halophilic Dunaliella salina strain显示文摘Dunaliella salina is a classic halophilic alga.However,its molecular mechanisms in response to high salinity at the post transcriptional level remain unknown.A unique halophilic alga strain,DS-CN1,was screened from four D.salina strains via cell biological,physiological,and biochemical methods.High-throughput sequencing of small RNAs(sRNAs)of DS-CN1 in culture medium containing 3.42-mol/L NaCl(SS group)or 0.05-mol/L NaCl(CO group)was performed on the BGISEQ-500 platform.The annotation and sequences of D.salina sRNAs were profiled.Altogether,44 novel salt stress-responsive microRNAs(miRNAs)with a relatively high C content,with the majority of them being 24 nt in length,were identified and characterized in DS-CN1.Twenty-one differentially expressed miRNAs(DEMs)in SS and CO were screened via bioinformatic analysis.A total of 319 putative salt stress-related genes targeted(104 overlapping genes)by novel miRNAs in this alga were screened based on our previous transcriptome sequencing research.Furthermore,these target genes were classified and enriched by GO and KEGG pathway analysis.Moreover,5 novel DEMs(dsa-mir3,dsa-mir16,dsa-mir17,and dsa-mir26 were significantly upregulated,and dsa-mir40 was significantly downregulated)and their corresponding 10 target genes involved in the 6 significantly enriched metabolic pathways were verified by quantitative real-time PCR.Next,their regulatory relationships were comprehensively analyzed.Lastly,a unique salt stress response metabolic network was constructed based on the novel DEM-target gene pairs.Taken together,our results suggest that 44 novel salt stress-responsive microRNAs were identified,and 4 of them might play important roles in D.salina upon salinity stress and contribute to clarify its distinctive halophilic feature.Our study will shed light on the regulatory mechanisms of salt stress responses. | Fan GAO Fangru NAN Jia FENG Junping LÜ Qi LIU Xudong LIU Shulian XIE | 2023 | Journal of Oceanology and Limnology2023，41，4： | 0 |
| 14 | Lack of CFAP54 causes primary ciliary dyskinesia in a mouse model and human patients显示文摘Primary ciliary dyskinesia(PCD)is a highly heterogeneous recessive inherited disorder.FAP54,the homolog of CFAP54 in Chlamydomonas reinhardtii,was previously demonstrated as the C1d projection of the central microtubule apparatus of flagella.A Cfap54 knockout mouse model was then reported to have PCD-relevant phenotypes.Through whole-exome sequencing,compound heterozygous variants c.2649_2657delinC(p.E883Dfs*47)and c.7312_7313insCGCAGGCTGAATTCTTGG(p.T2438delinsTQAEFLA)in a new suspected PCD-relevant gene,CFAP54,were identified in an individual with PCD.Two missense variants,c.4112A>C(p.E1371A)and c.6559C>T(p.P2187S),in CFAP54 were detected in another unrelated patient.In this study,a minigene assay was conducted on the frameshift mutation showing a reduction in mRNA expression.In addition,a CFAP54 in-frame variant knock-in mouse model was established,which recapitulated the typical symptoms of PCD,including hydrocephalus,infertility,and mucus accumulation in nasal sinuses.Correspondingly,two missense variants were deleterious,with a dramatic reduction in mRNA abundance from bronchial tissue and sperm.The identification of PCD-causing variants of CFAP54 in two unrelated patients with PCD for the first time provides strong supportive evidence that CFAP54 is a new PCD-causing gene.This study further helps expand the disease-associated gene spectrum and improve genetic testing for PCD diagnosis in the future. | Xinyue Zhao Haijun Ge Wenshuai Xu Chongsheng Cheng Wangji Zhou Yan Xu Junping Fan Yaping Liu Xinlun Tian Kai-Feng Xu Xue Zhang | 2023 | Frontiers of Medicine2023，17，6： | 0 |
| 15 | Video super-resolution reconstruction based on deep convolutional neural network and spatio-temporal similarity显示文摘Existing learning-based super-resolution(SR) reconstruction algorithms are mainly designed for single image, which ignore the spatio-temporal relationship between video frames.Aiming at applying the advantages of learning-based algorithms to video SR field, a novel video SR reconstruction algorithm based on deep convolutional neural network(CNN) and spatio-temporal similarity(STCNN-SR) was proposed in this paper.It is a deep learning method for video SR reconstruction, which considers not only the mapping relationship among associated low-resolution(LR) and high-resolution(HR) image blocks, but also the spatio-temporal non-local complementary and redundant information between adjacent low-resolution video frames.The reconstruction speed can be improved obviously with the pre-trained end-to-end reconstructed coefficients.Moreover, the performance of video SR will be further improved by the optimization process with spatio-temporal similarity.Experimental results demonstrated that the proposed algorithm achieves a competitive SR quality on both subjective and objective evaluations, when compared to other state-of-the-art algorithms. | Li Linghui Du Junping Liang Meiyu Ren Nan Fan Dan | 2016 | The Journal of China Universities of Posts and Telecommunications2016，23，5： | 0 |
| 16 | Comparison study of two aldehyde group finishing agents in surface modification of up-conversion luminescence materials显示文摘起来变换光材料的表面修正( Na [ Y0.57Yb0.39Er0.04 ] F4 由氨基的组修改了)由 grafting 并且与醛组一起修改借助于 Fourier 变换被学习红外线的光谱学( FTIR ),扫描电子显微镜学( SEM ), thermogravimetric 分析( TGA ),并且排放光谱(他们)。表面修正效果用二个不同完成代理人, p-phthalaldehyde 和 glutaraldehyde 被比较。起来变换光材料的表面能被二的醛组修改完成代理人,系统的可分散性和 p-phthalaldehyde 修改的起来变换光材料的 thermostability ,这被发现比 glutaraldehyde 修改的材料的那些好,并且 p-phthalaldehyde 修改的材料的发光紧张被增加。p-phthalaldehyde 修改的材料的 AI (在到标本的全部的团的标本的推迟的部分质量的比率) 比 glutaraldehyde 修改的材料的高。因为一个完成的代理人比 glutaraldehyde 的好,装饰 p-phthalaldehyde 完成,这显然被看见因为一个完成的代理人比 glutaraldehyde 的好。另外, p-phthalaldehyde 是一个好完成代理人的原因也被解释。 | CUI Lili FAN Huili XIAO Junping XU Xiaowei | 2008 | Rare Metals2008，27，2： | 0 |
| 17 | Pattern synthesis of antennas based on a modified particle swarm optimization algorithm显示文摘In order to overcome the drawbacks of standard particle swarm optimization(PSO)algorithm,such as prematurity and easily trapping in local optimum,a modified PSO algorithm is proposed,in which special techniques,as global best perturbation and inertia weight jump threshold are adopted.The convergence speed and accuracy of the algo-rithm are improved.The test by some benchmark problems shows that the proposed algorithm achieves relatively higher performance.Thereafter,the applications of the modified PSO in the radiation pattern synthesis of antenna arrays are presented. | JIN Ronghong YUAN Zhihao GENG Junping FAN Yu LI Jiajing | 2007 | Frontiers of Electrical and Electronic Engineering in China2007，2，4： | 0 |
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