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| 1 | Surgical resection with hyperthermic intraperitoneal chemotherapy for gastric cancer patients with peritoneal dissemination显示文摘 | ChenLi MinYan JunChen MinXiang Zheng GangZhu Hao RanYin Yan ZhengLin | 2010 | J Surg Oncol2010，，5： | 1 |
| 2 | A composite inhibitor used in oilfield: MA-AMPS and imidazoline显示文摘 | Ting Gu Pengcheng Su Xiaoyan Liu Junchen Zou Xinying Zhang Yan Hu | 2013 | Journal of Petroleum Science and Engineering2013，，： | 1 |
| 3 | Investigating the ENSO prediction skills of the Beijing Climate Center climate prediction system version 2显示文摘The El Niño-Southern Oscillation(ENSO)ensemble prediction skills of the Beijing Climate Center(BCC)climate prediction system version 2(BCC-CPS2)are examined for the period from 1991 to 2018.The upper-limit ENSO predictability of this system is quantified by measuring its“potential”predictability using information-based metrics,whereas the actual prediction skill is evaluated using deterministic and probabilistic skill measures.Results show that:(1)In general,the current operational BCC model achieves an effective 10-month lead predictability for ENSO.Moreover,prediction skills are up to 10–11 months for the warm and cold ENSO phases,while the normal phase has a prediction skill of just 6 months.(2)Similar to previous results of the intermediate coupled models,the relative entropy(RE)with a dominating ENSO signal component can more effectively quantify correlation-based prediction skills compared to the predictive information(PI)and the predictive power(PP).(3)An evaluation of the signal-dependent feature of the prediction skill scores suggests the relationship between the“Spring predictability barrier(SPB)”of ENSO prediction and the weak ENSO signal phase during boreal spring and early summer. | Yanjie Cheng Youmin Tang Tongwen Wu Xiaoge Xin Xiangwen Liu Jianglong Li Xiaoyun Liang Qiaoping Li Junchen Yao Jinghui Yan | 2022 | Acta Oceanologica Sinica2022，41，5： | 0 |
| 4 | Themis suppresses the effector function of CD8^(+)T cells in acute viral infection显示文摘CD8^(+)T cells play a central role in antiviral immune responses.Upon infection,naive CD8^(+)T cells differentiate into effector cells to eliminate virus-infected cells,and some of these effector cells further differentiate into memory cells to provide long-term protection after infection is resolved.Although extensively investigated,the underlying mechanisms of CD+T-cell differentiation remain incompletely understood.Themis is a T-cell-specific protein that plays critical roles in T-cell development.Recent studies using Themis T-cell conditional knockout mice also demonstrated that Themis is required to promote mature CD8^(+)T-cell homeostasis,cytokine responsiveness,and antibacterial responses.In this study,we used LCMV Armstrong infection as a probe to explore the role of Themis in viral infection.We found that preexisting CD8^(+)T-cell homeostasis defects and cytokine hyporesponsiveness do not impair viral clearance in Themis T-cell conditional knockout mice.Further analyses showed that in the primary immune response,Themis deficiency promoted the differentiation of CD8^(+)effector cells and increased their TNF and IFNy production.Moreover,Themis deficiency impaired memory precursor cell(MPEC)differentiation but promoted short-lived effector cell(SLEC)differentiation.Themis deficiency also enhanced effector cytokine production in memory CD8^(+)T cells while impairing central memory CD8^(+)T-cell formation.Mechanistically,we found that Themis mediates PD-1 expression and its signaling in effector CD8^(+)T cells,which explains the elevated cytokine production in these cells when Themis is disrupted. | Jian Tang Xian Jia Jian Li Junchen Dong Jiayu Wang Wanyun Li Yuzhen Zhu Yanyan Hu Bowen Hou Chunjie Lin Yu Cong Tong Ren Changsheng Yan Hongying Yang Qian Lai Haiping Zheng Yuzhou Bao Namrata Gautam Hong-Rui Wang Bing Xu Xiao Lei Chen Qing Li Nicholas R.J.Gascoigne Guo Fu | 2023 | Cellular & Molecular Immunology2023，20，5： | 0 |
| 5 | Influence of MnO_(x)deposition on TiO_(2)nanotube arrays for electrooxidation显示文摘TiO_(2)has demonstrated outstanding performance in electrochemical advanced oxidation processes(EAOPs)due to its structural stability and high oxygen overpotential.However,there is still much room for improving its electrochemical activity.Herein,narrow bandgap manganese oxide(MnO_(x))was composited with TiO_(2)nanotube arrays(TiO_(2)NTAs)that in-situ oxidized on porous Ti sponge,forming the MnO_(x)-TiO_(2)NTAs anode.XANES and XPS analysis further proved that the composition of MnO_(x)is Mn2O3.Electrochemical characterizations revealed that increasing the composited concentration of MnO_(x)can improve the conductivity and reduce oxygen evolution potential so as to improve the electrochemical activity of the composited MnO_(x)-TiO_(2)NTAs anode.Meanwhile,the optimal degradation rate of benzoic acid(BA)was achieved using MnO_(x)-TiO_(2)NTAs with a MnO_(x)concentration of 0.1 mmol L^(-1),and the role of MnO_(x)was proposed based on DFT calculation.Additionally,the required electrical energy(EE/O)to destroy BA was optimized by varying the composited concentration of MnO_(x)and the degradation voltage.These quantitative results are of great significance for the design and application of high-performance materials for EAOPs. | Kaihang Zhang Yuanzheng Zhang Su Liu Xin Tong Junfeng Niu Dong Wang Junchen Yan Zhaoyang Xiong John Crittenden | 2023 | Green Energy & Environment2023，8，2： | 0 |
| 6 | Progress of MJO Prediction at CMA from Phase I to Phase II of the Sub-Seasonal to Seasonal Prediction Project显示文摘As one of the participants in the Subseasonal to Seasonal(S2S)Prediction Project,the China Meteorological Administration(CMA)has adopted several model versions to participate in the S2S Project.This study evaluates the models’capability to simulate and predict the Madden-Julian Oscillation(MJO).Three versions of the Beijing Climate Center Climate System Model(BCC-CSM)are used to conduct historical simulations and re-forecast experiments(referred to as EXP1,EXP1-M,and EXP2,respectively).In simulating MJO characteristics,the newly-developed high-resolution BCC-CSM outperforms its predecessors.In terms of MJO prediction,the useful prediction skill of the MJO index is enhanced from 15 days in EXP1 to 22 days in EXP1-M,and further to 24 days in EXP2.Within the first forecast week,the better initial condition in EXP2 largely contributes to the enhancement of MJO prediction skill.However,during forecast weeks 2–3,EXP2 shows little advantage compared with EXP1-M because the increased skill at MJO initial phases 6–7 is largely offset by the degraded skill at MJO initial phases 2–3.Particularly at initial phases 2–3,EXP1-M skillfully captures the wind field and Kelvin-wave response to MJO convection,leading to the highest prediction skill of the MJO.Our results reveal that,during the participation of the CMA models in the S2S Project,both the improved model initialization and updated model physics played positive roles in improving MJO prediction.Future efforts should focus on improving the model physics to better simulate MJO convection over the Maritime Continent and further improve MJO prediction at long lead times. | Junchen YAO Xiangwen LIU Tongwen WU Jinghui YAN Qiaoping LI Weihua JIE | 2023 | Advances in Atmospheric Sciences2023，40，10： | 0 |
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