|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Comparison of quality of life between urban and rural gastric cancer patients and analysis of influencing factors显示文摘AIM: The conception of quality of life has been widely accepted by clinic doctors. Evaluations of the treatment effect of chronic diseases have been changed to depend not only on the survival time, but also on the quality of life of the patients. Fuzhou City and Changle County are highincidence areas of the gastric cancer in Fujian Province. The aims of this research were to compare the quality of life of urban patients with that of rural patients and analyze the factors influencing quality of life of gastric cancer patients in Fujian Province. METHODS: The samples were drawn with cluster sampling. The urban sample consisted of 162 patients aged 25 to 75 with 143 males and 19 females. The rural sample consisted of 200 patients aged 32 to 78 with 166 males and 34 females. The patients in both the urban and rural areas were investigated, and their scores on 21 items reflecting the quality of life were measured. The methods of ttest and stepwise regression were used to analyze the data. RESULTS: The average total scores of quality of life of the urban patients and rural patients were 64.11 and 68.69 respectively. There was a significant difference between the means of two samples (P = 0.0004). Seven variables in the regression model estimated by the urban sample and 4 variables in the model by the rural sample were at the level of significance α=0.05. Family income, nutrition and rehabilitating exercise were selected into both the urban and rural regression models. CONCLUSION: Most of the gastric cancer patients have poor quality of life in Fujian Province and the rural patients have lower quality of life than that of urban patients. The patients having more family income have better quality of life, and enhanced nutrition and doing rehabilitating exercise are helpful in improving the quality of life of the gastric cancer patients. | JunTian Zhen-ChunChen BinWu XinMeng | 2004 | World Journal of Gastroenterology2004，10，20： | 22 |
| 2 | Nutritional status and quality of life of the gastric cancer patients in Changle County of China显示文摘AIM: To analyze the relation between nutrition and quality of life in the stomach cancer patients, evaluate the intake of daily nutrition of the patients, and study the feasibility of nutrition intervention in improving quality of life of the stomach cancer patients.METHODS: A total of 285 surgical stomach cancer patients reported in the Changle Cancer Registry from 2002 to 2003 were investigated with respect to their diet and quality of life. Daily nutrition intakes of the patients were calculated according to the Food Composition Database, and these data were compared with the reference values proposed by the Chinese Nutrition Society. The partial correlation was used to analyze the relationship between nutrition and quality of life in the patients. Stepwise multiple regression analyses were conducted to analyze the factors influencing nutrition intake in stomach cancer patients.RESULTS: Except vitamin C, there were statistical correlations between the nutrition and quality of life in stomach cancer patients, and differences of the daily nutrition intake among three groups (good, modest and bad quality of life) of the patients were significant. Most of the stomach cancer patients had a lower daily nutrition intake than the reference values. At the significance level α = 0.05, the factors influencing the daily nutrition intake of the patients were number of meals a day, family income, way of operation, exercise and age.CONCLUSION: The nutritional status of the operated patients with stomach cancer may impact on their quality of life. The stomach cancer patients in Changle County have a low level of daily nutrition intake, which suggests that they have a bad nutritional status. To improve the quality of life of the patients, the nutrition intervention should be conducted. Increasing times of meals a day and having a high-protein, high-calorie foods can improve the nutritional status of the stomach cancer patients.Moreover, exercise for rehabilitation can whet the appetite of the patients and recover their body function, which in turn may improve the quality of life of the stomach cancer patients. | JunTian Jian-ShunChen | 2005 | World Journal of Gastroenterology2005，11，11： | 12 |
| 3 | Interpretation of breast cancer screening guideline for Chinese women显示文摘Breast cancer is the most common malignant tumor in Chinese women.Early screening is the best way to improve the rates of early diagnosis and survival of breast cancer patients.The peak onset age for breast cancer in Chinese women is considerably younger than those in European and American women.It is imperative to develop breast cancer screening guideline that is suitable for Chinese women.By summarizing the current evidence on breast cancer screening in Chinese women,and referring to the latest guidelines and consensus on breast cancer screening in Europe,the United States,and East Asia,the China Anti-Cancer Association and National Clinical Research Center for Cancer(Tianjin Medical University Cancer Institute and Hospital)have formulated population-based guideline for breast cancer screening in Chinese women.The guideline provides recommendations on breast cancer screening for Chinese women at average or high risk of breast cancer according to the following three aspects:age of screening,screening methods,and screening interval.This article provides more detailed information to support the recommendations in this guideline and to provide more direction for current breast cancer screening practices in China. | Yubei Huang Zhongsheng Tong Kexin Chen Ying Wang Peifang Liu Lin Gu Juntian Liu Jinpu Yu Fengju Song Wenhua Zhao Yehui Shi Hui Li Huaiyuan Xiao Xishan Hao | 2019 | Cancer Biology & Medicine2019，16，4： | 10 |
| 4 | Clinicopathologic and molecular characteristics of 44 patients with pure secretory breast carcinoma显示文摘Objective: Secretory breast carcinoma(SBC) is a rare type of breast malignancy, accounting for less than 0.02% of all infiltrating breast malignancies. The pure SBC, a type of SBC without another type of breast malignant neoplasm, is particularly rare. This study aimed to investigate the clinicopathologic and molecular features of pure SBC.Methods: The main pathological parameters such as estrogen receptor(ER), progesterone receptor(PR), and human epithelial growth factor receptor 2(C-erbB-2) were detected by immunohistochemistry(IHC), and the clinicopathologic and prognostic difference were compared with invasive ductal carcinoma(IDC). Fluorescent in situ hybridization(FISH) and reverse transcription polymerase chain reaction(RT-PCR) was performed to identify the ETV6-NTRK3 rearrangement of SBC.Results: We found that the positivity rates of ER, PR, C-erbB-2, p53, and S-100 were 47.7%(21/44), 52.3%(23/44), 36.4%(16/44), 27.3%(12/44), and 95.5%(42/44), respectively, which were higher than those reported in previous studies. Special periodic acid-Schiff analysis was performed in 36 patients, and the value of the Ki-67 index ranged from 1% to 50%(mean value:10%). Interestingly, most patients with pure SBC harbored an ETV6-NTRK3 rearrangement with an 88.6%(39/44) expression rate. Compared with IDC, the tumor size of most patients with SBC was larger than 2 cm(P = 0.024). Ultrasound showed benign lesions, and the total misdiagnosis rate was higher(P = 0.020). Although the pathological classification was mostly triple-negative breast cancers(P = 0.036), there was less metastasis(P = 0.029), and the overall prognosis was better than that of the IDC group.Conclusions: Although axillary lymph node metastasis, local recurrence, or distant metastasis may occur, SBC is also considered an indolent neoplasm with a good prognosis. Once diagnosed, surgical treatment should be performed as soon as possible,followed by appropriate adjuvant chemotherapy, irradiation, and endocrine therapies. | Lijuan Li Nan Wu Fangxuan Li Lingmei Li Lijuan Wei Juntian Liu | 2019 | Cancer Biology & Medicine2019，16，1： | 8 |
| 5 | Ultrasound features of extranodal extension in the metastatic cervical lymph nodes of papillary thyroid cancer:a case-control study显示文摘Objective:Extranodal extension in cervical lymph nodes is an important risk factor for the progression and prognosis of papillary thyroid cancer.The purpose of this study was to identify the common and characteristic preoperative ultrasonography features that are associated with the pathologic extranodal extension of metastatic papillary thyroid carcinoma.Methods:We retrospectively assessed and compared clinicopathologic and ultrasound features between 60 papillary thyroid cancer patients with extranodal extension and 120 control patients with papillary thyroid cancer without extranodal extension.Results:With respect to the pathological N stage and clinicopathologic features,N1b stage papillary thyroid carcinomas were more frequently found in patients who were extranodal extension-positive,in comparison with those who were extranodal extension-negative(78.3%vs.63.3%,P=0.043).Extranodal extension was detected most frequently in level VI cervical lymph nodes(48.7%).In our univariate analysis of patients with papillary thyroid carcinoma,cervical lymph nodes with extranodal extension showed higher incidences of node matting,microcalcification,cystic area,aspect ratio<2,and larger diameter than those without extranodal extension(all P<0.05).Our multivariate analysis demonstrated that node matting and cystic area were independent risk factors for the presence of extranodal extension[odds ratio(OR):4.751,95%confidence interval(CI):1.212~18.626,P=0.025;OR:2.707,95%CI:1.127~6.502,P=0.026].Conclusions:Common ultrasound features may indicate the presence of extranodal extension in patients with metastatic cervical lymph nodes of papillary thyroid carcinoma. | Jiali Mu Xiaofeng Liang Fangxuan Li Juntian Liu Sheng Zhang Jing Tian | 2018 | Cancer Biology & Medicine2018，15，2： | 7 |
| 6 | Simultaneous quantification of ginsenoside Rg1 and its metabolites by HPLC–MS/MS:Rg1 excretion in rat bile, urine and feces显示文摘Ginsenoside Rg1(Rg1), the major effective component of ginseng, has been shown to have multiple bioactivities, but low oral bioavailability. The aim of this study was to develop a simple, sensitive and rapid high performance liquid chromatography–tandem mass spectrometry(LC–MS/MS) method, which could be used to validate and quantify the concentrations of Rg1 and its metabolites in Sprague-Dawley rat bile,urine, and feces after oral administration(25 mg/kg). Calibration curves offered satisfactory linearity(r40.995)within the determined ranges. Both intra-day and inter-day variances were less than 15%, and the accuracy was within 80–120%. The excretion recoveries of Rg1, ginsenoside Rh1(Rh1), and protopanaxatriol(Ppt) in bile,urine, and feces combined were all greater than 70%. The fecal excretion recoveries of Rg1, Rh1, and Ppt were40.11%, 22.19%, and 22.88%, respectively, whereas 6.88% of Rg1 and 0.09% of Rh1 were excreted in bile.Urinary excretion accounted for only 0.04% of Rg1. In conclusion, the observed excretion profiles for Rg1 and its metabolites after oral administration are helpful for understanding the poor oral bioavailability of Rg1 and will aid further investigations of Rg1 as a pharmacologically active component. | Chiyu He Ru Feng Yupeng Sun Shifeng Chu Ji Chen Chao Ma Jie Fu Zhenxiong Zhao Min Huang Jiawen Shou Xiaoyang Li Yuzhu Wang Jinfeng Hu Yan Wang Juntian Zhang | 2016 | Acta Pharmaceutica Sinica B2016，6，6： | 6 |
| 7 | Active surveillance as a management strategy for papillary thyroid microcarcinoma显示文摘Active surveillance(AS)can be considered as a treatment strategy for low risk papillary thyroid microcarcinoma(PTMC),with the absence of clinically apparent lymph nodes,extrathyroidal extensions,and distant metastasis.After reviewing the reports on AS of low risk PTMCs worldwide,we introduced AS,and discussed the selection criteria for active surveillance candidates based on different guidelines and the follow-up schedules.Moreover,the requirement of cytological diagnosis,progression evaluation methods,necessity of thyrotropin suppression,and medical costs were issues that both clinicians and patients considered.The usefulness of AS for low risk PTMC patients depended on accurate and confidential evaluation of patient risk.Clinicians may adopt measures like dynamic monitoring,risk stratification,and making personal follow-up schedules to minimize these potential risks.By appropriately selecting PTMC patients,AS can be an effective alternative treatment to immediate surgery. | Huan Zhang Xiangqian Zheng Juntian Liu Ming Gao Biyun Qian | 2020 | Cancer Biology & Medicine2020，17，3： | 5 |
| 8 | Variations of very low-density lipoprotein receptor subtype expression in gastrointestinal adenocarcinoma cells with various differentiations显示文摘AIM: This study is aimed at investigating the expression and possible significances of very low-density lipoprotein receptor (VLDLR) subtypes in gastroenteric adenocarcinoma tissues and cells with various differentiations. METHODS: Thirty-one cases of gastroenteric carcinoma/ adjacent normal tissues were enrolled in the study, which were diagnosed and classified by the clinicopathological diagnosis. The expression of VLDLR subtypes was detected in gastroenteric carcinoma/adjacent normal tissues and three various differentiated human gastric adenocarcinoma cell lines (MKN28, SGC7901 and MKN45) by reverse transcription polymerase chain reaction (RT-PCR) and Western blot analysis.RE,SULTS: Two VLDLR subtypes, namely, type Ⅱ VLDLR and type Ⅰ VLDLR, were found to express changes in gastroenteric carcinoma tissues, their adjacent normal tissue, and gastric adenocarcinoma cell lines as well. Type Ⅱ VLDLR is predominantly expressed in poorly- or moderately-differentiated gastroenteric carcinoma tissues and gastric adenocarcinoma cell lines, whereas type ⅠVLDLR is mainly detected in well-differentiated intestinal carcinoma tissues and gastric adenocarcinoma cells compared with the adjacent normal tissues. CONCLUSION: The results suggested that the variations of the VLDLR subtype expression might be correlated with the progress and differentiation of gastroenteric carcinoma. | TaoChen FanWu Feng-MingChen JunTian ShenQu | 2005 | World Journal of Gastroenterology2005，11，18： | 5 |
| 9 | MicroRNA-106b~25 expressions in tumor tissues and plasma of patients with gastric cancers显示文摘 | Rupeng Zhang Weijia Wang Fangxuan Li Hui Zhang Juntian Liu | 2014 | Medical Oncology2014，，10： | 3 |
| 10 | C-Reactive Protein-Induced Expression of CD40-CD40L and the Effect of Lovastatin and Fenofibrate on It in Human Vascular Endothelial Cells 显示文摘 | Rong L Juntian L Weijie G | 2004 | Pharm Soc Jap2004，27，10： | 1 |
| 11 | Fluorescence characterization and microbial degradation of dissolved organic matter leached from salt marsh plants in the Yellow River Delta显示文摘盐沼植被是沿海水体中溶解有机物(Dissolved Organic Matter,DOM)的重要贡献者。然而,不同盐沼植物释放DOM的动力学特征尚缺乏系统研究和比较。黄河三角洲湿地是中国东海岸面积最大,保护最完善的沿海生态系统之一。本论文研究了2016年10月从黄河三角洲(Yellow River Delta,YRD)盐沼中采集的三种常见沼泽植物(芦苇(Phragmites australis),碱蓬(Suaeda salsa)和獐茅(Aeluropus littoralis)的DOM释放过程。通过测定溶解有机碳(Dissolved Organic Carbon,DOC)和溶解氮(Dissolved Nitrogen,DN)发现,植物叶片释放的DOM浓度远高于其根和茎。在27天的培养期内,平均有15%的生物碳和30%的生物氮以DOC和DN的形式通过植物叶片释放。从植物中释放的DOM非常不稳定,在27天的培养期内,细菌共消耗了92.4%-98.1%的DOC和88.0%-94.6%的DN。植物释放DOM的荧光特性表明,发色溶解的有机物(Chromophoric Dissolved Organic Matter,CDOM)是DOM的主要组分,而类蛋白组分是植物释放CDOM的主要组分。细菌的降解作用改变了DOM的荧光性质和化学组成。上述的室内研究结果得到了实地调查的充分支撑,表明在深秋时期黄河口湿地有大量DOM溢出。本研究结果表明,盐沼植物释放的DOM是沼泽和沿海水域DOC和DN的重要来源,而且易降解DOC和DN为黄河口湿地和邻近沿海水域中的微生物群落提供了重要的食物来源。 | Tao Zhang Zhihua Feng Chunle Luo Yixin Sun Jinzhen Li Juntian Xu Xuchen Wang | 2020 | Journal of Plant Ecology2020，13，5： | 1 |
| 12 | UV- A enhanced growth and UV - B induced positive effects in the recovery of photochemical yieht in Gracilaria lemaneiformis (Rhodophyta) 显示文摘 | Juntian Xu Kunshan Gao | 2010 | Journal of Photo- chemistry and Photobiology B: Biology2010，100，3： | 1 |
| 13 | C-Reactive Protein-Induced Expression of CD40-CD40L and the Effect of Lovastatin and Fenofibrate on It in Human Vascular Endothelial Cells 显示文摘 | Rong L Juntian L Weijie G | 2004 | Pharm Soc Jap2004，27，10： | 1 |
| 14 | Caulophine protects cardiomyocytes from oxidative and ischemic injury显示文摘 | Kaiwei Si Juntian Liu He L | 2010 | J Pharm Sci2010，133，4： | 1 |
| 15 | Monitoring the spontaneous wetting process of hydrophobic microporous membrane assisted by alternating current impedance spectroscopy显示文摘In the process of membrane absorption,spontaneous wetting of hydrophobic microporous membrane causes membrane modification and increases membrane phase mass transfer resistance,which have attracted wide interest.However,due to the limitations of previous testing methods,the study of the spontaneous membrane wetting process is limited.Herein,we present a method for monitoring spontaneous membrane wetting by measuring its alternating current(AC)impedance.The impedance tests of the PVDF flat membranes and hollow fiber membranes were conducted in a two-electrode system.The results of equivalent circuit fitting indicate that the impedance value of the unwetted membrane is about 1.02×10^(10)Ω,which is close to the theoretical value of 1.4×10^(10)Ω,and this method can quantify the electrochemical impedance value of membranes with different degrees of spontaneous wetting.In addition,a method of impedance test for real-time monitoring of spontaneous wetting was designed.During the experiment,the timeliness and continuity of this method are confirmed with exact judgment under different conditions.In future work,the impedance data will be used to build model to predict the percentage of membrane wetting degree. | Juntian Xiao Qian Sun Liying Liu Zhongwei Ding | 2021 | Chinese Journal of Chemical Engineering2021，34，11： | 1 |
| 16 | Ginsenoside Rgl increases ischemia-induced cell proliferation and survival in the dentate gyrus of adult gerbils 显示文摘 | LIHONG SHEN JUNTIAN ZHANG | 2003 | Neuroscience Letters2003，344，1： | 1 |
| 17 | Applied research of fracture for three-points bending of tool steel 显示文摘 | Rui Zhiyuan Li Youtang Zhao Juntian | 2005 | Key Engineering Materials2005，298，2： | 1 |
| 18 | Ginsenoside Rg_1 increasesischemia-induced cell proliferation and survival in thedentate gyrus of adult gerbils 显示文摘 | Shen Lihong Zhang Juntian | 2003 | Neurosci Lett2003，344，1： | 1 |
| 19 | Effects of asiaticoside on levels of podocyte cytoskeletal proteins and renal slit diaphragm proteins in adriamycin-induced rat nephropathy显示文摘 | Zhu Wang Juntian Liu Wansen Sun | 2013 | Life Sciences2013，，： | 1 |
| 20 | Assessment of Traffic Noise Pollution from 1989 to 2003 in Lanzhou City 显示文摘 | Guo Xiama Yu Juntian | 2006 | Environmental Monitoring and Assessment2006，，123： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员