|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Ehealth:Low FODMAP diet vs Lactobacillus rhamnosus GG in irritable bowel syndrome显示文摘AIM:To investigate the effects of a low fermentable,oligosaccharides,disaccharides,monosaccharides and polyols diet(LFD)and the probiotic Lactobacillus rhamnosus GG(LGG)in irritable bowel syndrome(IBS).METHODS:Randomised,unblinded controlled trial on the effect of 6-wk treatment with LFD,LGG or a normal Danish/Western diet(ND)in patients with IBS fulfilling Rome III diagnostic criteria,recruited betweenNovember 2009 and April 2013.Patients were required to complete on a weekly basis the IBS severity score system(IBS-SSS)and IBS quality of life(IBS-QOL)questionnaires in a specially developed IBS web selfmonitoring application.We investigated whether LFD or LGG could reduce IBS-SSS and improve QOL in IBS patients.RESULTS:One hundred twenty-three(median age 37years,range:18-74 years),90(73%)females were randomised:42 to LFD,41 to LGG and 40 to ND.A significant reduction in mean±SD of IBS-SSS from baseline to week 6 between LFD vs LGG vs ND was revealed:133±122 vs 68±107,133±122 vs 34±95,P<0.01.Adjusted changes of IBS-SSS for baseline covariates showed statistically significant reduction of IBS-SSS in LFD group compared to ND(IBS-SSS score75;95%CI:24-126,P<0.01),but not in LGG compared to ND(IBS-SSS score 32;95%CI:18-80,P=0.20).IBS-QOL was not altered significantly in any of the three groups:mean±SD in LFD 8±18 vs LGG 7±17,LFD 8±18 vs ND 0.1±15,P=0.13.CONCLUSION:LFD is efficacious for patients with IBS. | Natalia Pedersen Nynne Nyboe Andersen Zsuzsanna Végh Lisbeth Jensen Dorit Vedel Ankersen Maria Felding Mette Hestetun Simonsen Johan Burisch Pia Munkholm | 2014 | World Journal of Gastroenterology2014，20，43： | 16 |
| 2 | Low-FODMAP diet reduces irritable bowel symptoms in patients with inflammatory bowel disease显示文摘AIM To investigate the effect of a low-FODMAP diet on irritable bowel syndrome(IBS)-like symptoms in patients with inflammatory bowel disease(IBD).METHODS This was a randomised controlled open-label trial of patients with IBD in remission or with mild-to-moderate disease and coexisting IBS-like symptoms(Rome III) randomly assigned to a Low-FODMAP diet(LFD) or a normal diet(ND) for 6 wk between June 2012 andDecember 2013. Patients completed the IBS symptom severity system(IBS-SSS) and short IBD quality of life questionnaire(SIBDQ) at weeks 0 and 6. The primary end-point was response rates(at least 50-point reduction) in IBS-SSS at week 6 between groups; secondary end-point was the impact on quality of life. RESULTS Eighty-nine patients, 67(75%) women, median age 40, range 20-70 years were randomised: 44 to LFD group and 45 to ND, from which 78 patients completed the study period and were included in the final analysis(37 LFD and 41 ND). There was a significantly larger proportion of responders in the LFD group(n = 30, 81%) than in the ND group(n = 19, 46%);(OR = 5.30; 95%CI: 1.81-15.55, P < 0.01). At week 6, the LFD group showed a significantly lower median IBSSSS(median 115; inter-quartile range [IQR] 33-169) than ND group(median 170, IQR 91-288), P = 0.02. Furthermore, the LFD group had a significantly greater increase in SIBDQ(median 60, IQR 51-65) than the ND group(median 50, IQR 39-60), P < 0.01.CONCLUSION In a prospective study, a low-FODMAP diet reduced IBS-like symptoms and increased quality of life in patients with IBD in remission. | Natalia Pedersen Dorit Vedel Ankersen Maria Felding Henrik Wachmann Zsuzsanna Végh Line Molzen Johan Burisch Jens Rikardt Andersen Pia Munkholm | 2017 | World Journal of Gastroenterology2017，23，18： | 15 |
| 3 | Follow-up of patients with functional bowel symptoms treated with a low FODMAP diet显示文摘AIM: To investigate patient-reported outcomes from, and adherence to, a low FODMAP diet among patients suffering from irritable bowel syndrome and inflammatory bowel disease.METHODS: Consecutive patients with irritable bowel syndrome(IBS) or inflammatory bowel disease(IBD) and co-existing IBS fulfilling the ROME Ⅲ criteria, who previously attended an outpatient clinic for low FODMAP diet(LFD) dietary management and assessment by a gastroenterologist, were invited to participate in a retrospective questionnaire analysis. The questionnaires were sent and returned by regular mail and gathered information on recall of dietarytreatment, efficacy, symptoms, adherence, satisfaction, change in disease course and stool type, and quality of life. Before study enrolment all patients had to sign an informed written consent.RESULTS: One hundred and eighty patients were included, 131(73%) IBS and 49(27%) IBD patients. Median age was 43 years(range: 18-85) and 147(82%) were females. Median follow-up time was 16 mo(range: 2-80). Eighty-six percent reported either partial(54%) or full(32%) efficacy with greatest improvement of bloating(82%) and abdominal pain(71%). The proportion of patients with full efficacy tended to be greater in the IBD group than in the IBS group(42% vs 29%, P = 0.08). There was a significant reduction in patients with a chronic continuous disease course in both the IBS group(25%, P < 0.001) and IBD group(23%, P = 0.002) along with a significant increase in patients with a mild indolent disease course of 37%(P < 0.001) and 23%(P = 0.002), respectively. The proportion of patients having normal stools increased with 41% in the IBS group(P < 0.001) and 66% in the IBD group(P < 0.001). One-third of patients adhered to the diet and high adherence was associated with longer duration of dietary course(P < 0.001). Satisfaction with dietary management was seen in 83(70%) IBS patients and 24(55%) IBD patients. Eightyfour percent of patients lived on a modified LFD, where some foods rich in FODMAPs were reintroduced, and 16% followed the LFD by the book without deviations. Wheat, dairy products, and onions were the foods most often not reintroduced by patients.CONCLUSION: These data suggest that a diet low in FODMAPs is an efficacious treatment solution in the management of functional bowel symptoms for IBS and IBD patients. | Louise Maagaard Dorit V Ankersen Zsuzsanna Végh Johan Burisch Lisbeth Jensen Natalia Pedersen Pia Munkholm | 2016 | World Journal of Gastroenterology2016，22，15： | 8 |
| 4 | Mature results of PulmonArt:Involved-field 3D radiotherapy(RT)and docetaxel/ cisplatin chemotherapy(CT)in a randomised phase 2 study comparing concurrent CT-RT followed by consolidation CT, with induction CT followed by concurrent CT-RT in patients(pts)with stage III non-small cell lung cancer(NSCLC): B5-06 显示文摘 | van Meerbeeck JP Felipe C Johan V | 2007 | J Thorac Oncol2007，2，8： | 1 |
| 5 | Critical factors and pitfalls affecting the extraction of acrylamide from foods: An optimization study 显示文摘 | Erik V Petersson Johan Rosen Charlotta Turner | 2006 | Analytica Chimica Acta2006，557，12： | 1 |
| 6 | Distant effect s of India Eurasia convergence and Mesozoic intracontinental deformation in Central Asia:Constraints from apatite fission-track thermo- chronology显示文摘 | Johan D G Michael M B Peter V H | 2006 | Journal of Asian Earth Sciences2006，，3： | 1 |
| 7 | Prevalence and correlates of self-reported pretransplant nonadherence with medication in heart,liver, and lung transplant candidates 显示文摘 | Fabienne D Johan V Ariane D | 2005 | Transplantation2005，79，11： | 1 |
| 8 | Journal status显示文摘 | Johan B Marko A R Herbert V S | 2006 | Scientometrics2006，69，3： | 1 |
| 9 | Short-term duodenal seal oil administration normalised n-6 to n-3 fatty acid ratio in rectal mucosa and ameliorated bodily pain in patients with inflammatory bowel disease显示文摘 | Tormod B Johan GB Merete V | | 0，，： | 1 |
| 10 | A renewable lignin-lactide copolymer and application in biobased compo- sites显示文摘 | Yi Linchung Johan V O Russell J L | 2013 | Sustainable Chemistry Engineering2013，1，10： | 1 |
| 11 | Land use change under con- ditions of high population pressure: The case of Java显示文摘 | Peter H Tom V Johan B | 1999 | Global Environmental Change1999，9，4： | 1 |
| 12 | Metal complexes as photo-andradiosensitizers显示文摘 | Johan E V | 1999 | Chem Rev1999，99，： | 1 |
| 13 | Clinical-radiologieal presentation and outcome of surgically treated pulmonary carcinoid tumours: a long-term single institution experience 显示文摘 | Liesbet S Johan V Georges D | 2004 | Lung Cancer2004，43，1： | 1 |
| 14 | Identification of positive real models in subspace identification by using regularization显示文摘 | Ivan G Tony V G Johan S | 2003 | IEEE Transactions on Automatic Control2003，48，10： | 1 |
| 15 | Accurate profile and flatness control on a modernized hot strip mill 显示文摘 | Johan V R Hedwig V Rainer M | 1996 | Iron and Steel Engineer1996，73，2： | 1 |
| 16 | Challenges in the Detection and Attribution of Northern Hemisphere Surface Temperature Trends Since 1850显示文摘Since 2007,the Intergovernmental Panel on Climate Change(IPCC)has heavily relied on the comparison between global climate model hindcasts and global surface temperature(ST)estimates for concluding that post-1950s global warming is mostly human-caused.In Connolly et al.,we cautioned that this approach to the detection and attribution of climate change was highly dependent on the choice of Total Solar Irradiance(TSI)and ST data sets.We compiled 16 TSI and five ST data sets and found by altering the choice of TSI or ST,one could(prematurely)conclude anything from the warming being“mostly human-caused”to“mostly natural.”Richardson and Benestad suggested our analysis was“erroneous”and“flawed”because we did not use a multilinear regression.They argued that applying a multilinear regression to one of the five ST series re-affirmed the IPCC's attribution statement.They also objected that many of the published TSI data sets were out-of-date.However,here we show that when applying multilinear regression analysis to an expanded and updated data set of 27 TSI series,the original conclusions of Connolly et al.are confirmed for all five ST data sets.Therefore,it is still unclear whether the observed warming is mostly human-caused,mostly natural or some combination of both. | Ronan Connolly Willie Soon Michael Connolly Sallie Baliunas Johan Berglund C.J.Butler Rodolfo Gustavo Cionco Ana G.Elias Valery M.Fedorov Hermann Harde Gregory W.Henry Douglas V.Hoyt Ole Humlum David R.Legates Nicola Scafetta Jan-Erik Solheim LászlóSzarka Víctor M.Velasco Herrera Hong Yan Weijia Zhang | 2023 | Research in Astronomy and Astrophysics2023，23，10： | 1 |
| 17 | Prevalence and correlates of self-reported pretransplant nonadherence with medication in heart,liver, and lung transplant candidates显示文摘 | Fabierme D Johan V Ariane D | 2005 | Transplantation2005，79，11： | 1 |
| 18 | Current status of phthaloeyanines in photodynamie therapy of cancer 显示文摘 | Cynthia M A Wesley M S Johan E V L | 2001 | J Porphyrins Phthalocyanines2001，5，： | 1 |
| 19 | Zinc partitioning between glass and silicate phases in historical and modern lead-zinc metallurgical slags from the Pribram district,Czech Republic显示文摘 | ETTLER V JOHAN Z TOURAY J C JELINEK E | 2000 | Comptes Rendus de I'Académie des Sciences Paris:Série Ⅱ2000，，： | 1 |
| 20 | Metal complexes as photo- and radiosensitizers显示文摘 | Hasrat A Johan E V | 1999 | Chem Rev1999，99，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员