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| 1 | Epidemiology of fungal infections in China显示文摘与 immunocompromised 主人的增加的数字,真菌的感染的流行病学的特征经历了世界范围的庞大的变化,在中国包括。在这份报纸,我们越过中国在真菌病上考察了存在数据总结可得到的流行病学的侧面。我们发现在中国的表面的真菌的感染的一般发生是稳定的,但是癣 capitis 的发生减少了,传播线路变化了。由对比,侵略真菌的感染的全面发生继续升起了。candidemia 的出现由除 C 以外的 Candida 种类引起了。albicans 和不平常的 Candida 种类最近在中国增加了的包括的一些。曲霉属菌引起的感染也在最近的年里宣传了,特别地与 azole 抵抗的曲霉属菌 fumigatus 的出现。cryptococcosis 的一个增加的趋势在中国被注意了,与 Cryptococcus neoformans var。grubii 圣 5 遗传型作为占优势的病原体孤立。回顾的研究建议了在中国的 Pneumocystis 肺病的流行病学的特征可能类似于在另外的发展中的国家的那些。地方性的真菌的感染例如在东北中国的 sporotrichosis,必须引起研究,诊断,并且处理警戒。当前,在中国的真菌病上的流行病学的数据可变、碎片。因此,关于在中国的真菌的感染的全国流行病学的研究是对改进国家健康的重要需要。 | Min Chen Yuan Xu Nan Hong Yali Yang Wenzhi Lei Lin Du Jingjun Zhao Xia Lei Lin Xiong Langqi Cai Hui Xu Weihua Pan Wanqing Liao | 2018 | Frontiers of Medicine2018，12，1： | 49 |
| 2 | Advances in on-chip photonic devices based on lithium niobate on insulator显示文摘Crystalline lithium niobate(LN)is an important optical material because of its broad transmission window that spans from ultraviolet to mid-infrared and its large nonlinear and electro-optic coefficients.Furthermore,the recent development and commercialization of LN-on-insulator(LNOI)technology has opened an avenue for the realization of integrated on-chip photonic devices with unprecedented performances in terms of propagation loss,optical nonlinearity,and electro-optic tunability.This review begins with a brief introduction of the history and current status of LNOI photonics.We then discuss the fabrication techniques of LNOI-based photonic structures and devices.The recent revolution in the LN photonic industry has been sparked and is still being powered by innovations of the nanofabrication technology of LNOI,which enables the production of building block structures,such as optical microresonators and waveguides of unprecedented optical qualities.The following sections present various on-chip LNOI devices categorized into nonlinear photonic and electro-optic tunable devices and photonic-integrated circuits.Some conclusions and future perspectives are provided. | JINTIAN LIN FANG BO YA CHENG JINGJUN XU | 2020 | Photonics Research2020，8，12： | 26 |
| 3 | Observation and hydrodynamic analysis of fast-start of yellow catfish (Pelteobagrus fulvidraco)显示文摘The kinematics and hydrodynamics of the escape response of yellow catfish (Pelteobagrus fulvidraco) is investigated. It is observed from digital high-speed camera that all the escape response of yellow catfish is a C-type fast-start, which is characterized by the C-shape of the fish body at the end of the first contraction of the lateral musculature. Based on the analysis of the mass center movement and the performance of the caudal fin, the fast-start process can be divided into two stages: in stage one the fish body rotates rapidly around its mass center and in stage two the fish begins moving straightly. Theoretically, the Weihs’ model is employed to obtain the forces, moments and turning angular accelerations acting on the fish during the escape response. The results are in good agreement with the experimental observation. Furthermore, muscle strain at different locations along the body is calculated. At last, the dynamical performance of the escape response is explained. | JINGJun YINXiezhen LUXiyun | 2005 | Progress in Natural Science:Materials International2005，15，1： | 12 |
| 4 | Effect of tip geometry and tip clearance on aerodynamic performance of a linear compressor cascade显示文摘The tip leakage flow between a blade and a casing wall has a strong impact on compressor pressure rise capability, efficiency, and stability. Consequently, there is a strong motivation to look for means to minimize its impact on performance. This paper presents the potential of passive tip leakage flow control to increase the aerodynamic performance of highly loaded compressor blades. Experimental investigations on a linear compressor cascade equipped with blade winglets mounted to the blade tips have been carried out. Results for a variation of the tip clearance and the winglet geometry are presented. Current results indicate that the use of proper tip winglets in a compressor cascade can positively affect the local aerodynamic field by weakening the tip leakage vortex. Results also show that the suction-side winglets are aerodynamically superior to the pressure-side or combined winglets. The suction-side winglets are capable of reducing the exit total pressure loss associated with the tip leakage flow and the passage secondary flow to a significant degree. | Zhong Jingjun Han Shaobing Lu Huawei Kan Xiaoxu | 2013 | Chinese Journal of Aeronautics2013，26，3： | 12 |
| 5 | Geometric Approach for Kinematic Analysis of a Class of 2-DOF Rotational Parallel Manipulators显示文摘Euler angles are commonly used as the orientation representation of most two degrees of freedom(2-DOF) rotational parallel mechanisms(RPMs),as a result,the coupling of two angle parameters leads to complexity of kinematic model of this family of mechanisms.While a simple analytical kinematic model with respect to those parameters representing the geometrical characteristics of the mechanism,is very helpful to improve the performance of RPMs.In this paper,a new geometric kinematic modeling approach based on the concept of instantaneous single-rotation-angle is proposed and used for the 2-DOF RPMs with symmetry in a homo-kinetic plane.To authors' knowledge,this is a new contribution to parallel mechanisms.By means of this method,the forwards kinematics of 2-DOF RPMs is derived in a simple way,and three cases i.e.4-4R mechanism(Omni-wrist III),spherical five-bar one,and 3-RSR&1-SS one demonstrate the validity of the proposed geometric method.In addition,a novel 2-DOF RPM architecture with virtual center-of-motion is presented by aid of the same method.The result provides a useful tool for simplifying the model and extending the application of the RPMs. | DONG Xin YU Jingjun CHEN Bin ZONG Guanghua | 2012 | Chinese Journal of Mechanical Engineering2012，25，2： | 11 |
| 6 | The resurgent landscape of xenotransplantation of pig organs in nonhuman primates显示文摘Organ shortage is a major bottleneck in allotransplantation and causes many wait-listed patients to die or become too sick for transplantation.Genetically engineered pigs have been discussed as a potential alternative to allogeneic donor organs.Although xenotransplantation of pig-derived organs in nonhuman primates(NHPs)has shown sequential advances in recent years,there are still underlying problems that need to be completely addressed before clinical applications,including(i)acute humoral xenograft rejection;(ii)acute cellular rejection;(iii)dysregulation of coagulation and inflammation;(iv)physiological incompatibility;and(v)cross-species infection.Moreover,various genetic modifications to the pig donor need to be fully characterized,with the aim of identifying the ideal transgene combination for upcoming clinical trials.In addition,suitable pretransplant screening methods need to be confirmed for optimal donor-recipient matching,ensuring a good outcome from xenotransplantation.Herein,we summarize the understanding of organ xenotransplantation in pigs-to-NHPs and highlight the current status and recent progress in extending the survival time of pig xenografts and recipients.We also discuss practical strategies for overcoming the obstacles to xenotransplantation mentioned above to further advance transplantation of pig organs in the clinic. | Xuan Zhang Quancheng Wang Jingjun Zhao Xiao Li Wei Peng Zhaoxu Yang Zhibin Lin Long Yang Rui Ding Kaishan Tao Kefeng Dou | 2021 | Science China(Life Sciences)2021，64，5： | 10 |
| 7 | Numeration and type synthesis of 3-DOF orthogonal translational parallel manipulators显示文摘Low-degree-of-freedom (Low-DOF) parallel manipulators (PMs) have drawn extensive interests, particularly in type synthesis in which two main formal approaches were established by using the reciprocal screw system theory and Lie group theory. This paper aims at numeration and type synthesis of orthogonal translational parallel manipulators (OTPMs) by resorting to an integration of the group- based method and graphical representation of the topology. For this purpose, the concept of Cartesian DOF-characteristic matrix, orig- inated from displacement subgroup and displacement submanifold, is proposed. A new approach based on the combination of the atlas of Cartesian DOF-characteristic matrix and the displacement group-theoretic method is addressed for both exhaustive classi cation and type synthesis of OTPMs. The proposed approach is prone to construct an orthogonal structure and is easy to realize the complete clas- si cation and exhaustive enumeration of this class of low-DOF PMs. | Jingjun Yu Jian S. Dai Shusheng Bi Guanghua Zong | 2008 | Progress in Natural Science:Materials International2008，18，5： | 10 |
| 8 | ;ast forward kinematics algorithm for real-time and ligh-precision control of the 3-RPS parallel mechanism显示文摘 | Yue WANG Jingjun YU Xu PEI | 2018 | Frontiers of Mechanical Engineering2018，13，3： | 9 |
| 9 | A unified approach to type synthesis of both rigid and flexure parallel mechanisms显示文摘Type synthesis of both rigid and compliant parallel mechanisms has become a hot issue in the field of mechanisms and robotics research in recent years. A unified approach to type synthesis of the two classes of mechanisms, however, has not been referred and investigated up to date. Based on the state-of-art analysis for several major type synthesis approaches related to rigid and compliant mechanisms, respectively, it proves feasible to establish a unified methodology for type synthesis of these two classes of mechanisms. That is a synthesis philosophy in terms of the hierarchy mapping between mathematic, physical, and mechanical building blocks in the framework of screw theory, as addressed in this paper. The key point of the proposed method lies in establishing the mapping among three different building blocks (i.e. geometric building block, kinematic or constraint building block, and mechanical building block). As a result, it makes the whole type synthesis process simple and visible. By using the proposed method, two examples are taken to verify the effectiveness for the type synthesis of both rigid and flexure mechanisms. The content of this paper may provide a theoretical frame for constructing a visualized algorithm or software about the unified type synthesis (or conceptual design) of both rigid and flexure parallel mechanisms. | YU JingJun LI ShouZhong PEI Xu BI ShuSheng ZONG GuangHua | 2011 | Science China(Technological Sciences)2011，54，5： | 8 |
| 10 | Numerical Simulation and Experimental Study of the Submarine's Cold Wake Temperature Character显示文摘The temperature difference of the submarine's wake on the sea surface is the base for the IR detection. In this paper, the temperature difference on the sea surface caused by the submarine's propellers and the submarine's hull is studied by solving the three dimensional N-S equations. The results show that under the condition of sea temperature surroundings of minus gradient, such as in summer the upper water's temperature is higher than the lower water, it is cold wake on the sea surface and hot wake on the submarine's plane. The temperature difference between the wake and the water around in the wake's initial part becomes more and more obvious as the wake's distance gets longer. Through the IR camera, the submarine's propeller wake is studied under the same temperature status. Obvious IR temperature difference signals can be observed and it is consistent with the numerical simulation for the submarine. | CHEN Shengtao ZHONG Jingjun SUN Peng | 2014 | Journal of Thermal Science2014，23，3： | 8 |
| 11 | Novel Annulus-shaped Flexure Pivot in Rotation Application and Dimensionless Design显示文摘Large-deflection flexure pivot is widely used in high precision rotation application, but there are less flexure configurations and simple and convenient design methods. This paper presents a novel large-deflection curved-compliant annulus-shaped flexure pivot composed of six curved beam flexure elements. It can offer more than 10°angular stroke theoretically. Firstly, main-motion pseudo-rigid-body method is introduced to establish the flexure pivot model. Although pseudo-rigid-body method can be used to analyze the large-deformation flexure pivot performance, the method is definitely a laborious and difficult task for designing this novel flexure pivot. In order to simply the designing process, dimension-design graphs based on the parametric models and finite element analysis is presented. Using the dimension-design method as a tool, the designers can determine the optimal geometry rapidly, based on the stiffness and rotation demands of an annulus-shaped flexure pivot. Finally, dimension-design graph examples are given whose primary design aims to achieve a rotation stroke of annulus-shaped flexure pivot. The finite element analysis results show that the relative designing error between anticipative rotation stroke and graph design result is less than 4%. The dimensionless method used in designing annulus-shaped flexure pivot can reduce design process in both time and complexity. The novel annulus-shaped flexure pivot and dimension-design method are helpful supplement to configuration and design method of large-deflection flexure pivot. | BI Shusheng ZHAO Shanshan SUN Minglei YU Jingjun ZONG Guanghua | 2009 | Chinese Journal of Mechanical Engineering2009，22，6： | 7 |
| 12 | Effect of blade tip winglet on the performance of a highly loaded transonic compressor rotor显示文摘The tip leakage flow has an important influence on the performance of transonic compressor.Blade tip winglet has been proved to be an effective method to control the tip leakage flow in compressor,while the physical mechanisms of blade tip winglet have been poorly understood.A numerical study for a highly loaded transonic compressor rotor has been conducted to understand the effect of varying the location of blade tip winglet on the performance of the rotor.Two kinds of tip winglet were designed and investigated.The effects of blade tip winglet on the compressor overall performance,stability and tip flow structure were presented and discussed.It is found that the interaction of the tip winglet with the flow in the tip region is different when the winglet is located at suction-side or pressure-side of the blade tip.Results indicate that the suction-side winglet(SW) is ineffective to improve the performance of compressor rotor.In addition,a significant stall range extension equivalent to 33.74% with a very small penalty in efficiency can be obtained by the pressure-side winglet(PW).An attempt has been made to explain the fundamental mechanisms of blade tip winglet in detail. | Han Shaobing Zhong Jingjun | 2016 | Chinese Journal of Aeronautics2016，29，3： | 7 |
| 13 | Intensive phototherapy vs.exchange transfusion for the treatment of neonatal hyperbilirubinemia:a multicenter retrospective cohort study显示文摘Background:Intensive phototherapy(IPT)and exchange transfusion(ET)are the main treatments for extreme hyperbilirubinemia.However,there is no reliable evidence on determining the thresholds for these treatments.This multicenter study compared the effectiveness and complications of IPT and ET in the treatment of extreme hyperbilirubinemia.Methods:This retrospective cohort study was conducted in seven centers from January 2015 to January 2018.Patients with extreme hyperbilirubinemia that met the criteria of ET were included.Patients were divided into three subgroups(low-,medium-,and high-risk)according to gestational week and risk factors.Propensity score matching(PSM)was performed to balance the data before treatment.Study outcomes included the development of bilirubin encephalopathy,duration of hospitalization,expenses,and complications.Mortality,auditory complications,seizures,enamel dysplasia,ocular motility disorders,athetosis,motor,and language development were evaluated during follow-up at age of 3 years.Results:A total of 1164 patients were included in this study.After PSM,296 patients in the IPT only group and 296 patients in the IPT plus ET group were further divided into the low-,medium-,and high-risk subgroups with 188,364,and 40 matched patients,respectively.No significant differences were found between the IPT only and IPT plus ET groups in terms of morbidity,complications,and sequelae.Hospitalization duration and expenses were lower in the low-and medium-risk subgroups in the IPT only group.Conclusions:In this study,our results suggest that IPT is a safe and effective treatment for extreme hyperbilirubinemia.The indication of ET for patients with hyperbilirubinemia could be stricter.However,it is necessary to have a contingency plan for emergency ET as soon as IPT is commenced especially for infants with risk factors.If IPT can be guaranteed and proved to be therapeutic,ET should be avoided as much as possible. | Meng Zhang Yang He Jun Tang Wenbin Dong Yong Zhang Benjin Zhang Hong Wan Quanmin Deng Lirong Guan Bin Xia Zhong Chen Min Ge Jing Zhao Wenxing Li Jingjun Pei Yi Qu Dezhi Mu | 2022 | Chinese Medical Journal2022，，5： | 7 |
| 14 | Second-harmonic generation using d(33)in periodically poled lithium niobate microdisk resonators显示文摘A fabrication process allowing for the production of periodically poled lithium niobate(PPLN)photonic devices with any domain pattern and unit size down to 200 nm is developed by combining semiconductor fabrication techniques and piezo-force-microscopy tips polarization.Based on this fabrication process,PPLN microdisk resonators with quality factors of 8×10~4 were fabricated from a Z-cut lithium niobate film.Second-harmonic generation(SHG)utilizing d(33)in the whole cavity was demonstrated in a PPLN microdisk with a 2μm-spatialperiod radial domain pattern.The SHG conversion efficiency was measured to be 1.44×10^(-5)m W^(-1).This work paves the way to fabricate complex PPLN photonic devices and to obtain efficient nonlinear optical effects that have wide applications in both classical and quantum optics. | ZHENZHONG HAO LI ZHANG WENBO MAO ANG GAO XIAOMEI GAO FENG GAO FANG BO GUOQUAN ZHANG JINGJUN XU | 2020 | Photonics Research2020，8，3： | 6 |
| 15 | Effect of Yupingfeng granules on the skin barrier in atopic dermatitis mice models显示文摘OBJECTIVE: To investigate effect of Yupingfeng granules, prepared with Chinese Medicines, on the wound healing and on the expression of aquaporin3(AQP3) and the skin barrier in the animal models of atopic dermatitis(AD).METHODS: Acute skin lesions of AD models were prepared using 2,4-dinitrochlorobenzo(DNCB) in mice and animals were treated with either Yupingfeng granules or placebo for two weeks. Skin wound healing outcome was assessed by measuring skin thickness, weight(quality) of the skin, and trans-epidermal water loss(TEWL). Expression of AQP3 mRNA and protein was assessed by reverse transcriotion polymerase chain reaction(RT-PCR)and immunoblotting, respectively.RESULTS: Yupingfeng granule treatment resulted in significant acceleration of wound healing with63.64% efficiency, which was significantly higher than that of placebo granule treatment(31.82%,P < 0.01 by Wilcoxon Rank-sum test). Skin thickness, weight of the wounded skin, and TEWL were significantly higher in the AD models compared to that of normal animals. Treatment with Yupingfeng granules resulted in significant decrease in skin thickness [(937 ± 31) vs(360 ± 21) μm, P < 0.01],weight of the wounded skin [(42 ± 4) vs(24 ± 5)mg, P < 0.01], and TEWL [(30 ± 4) vs(13 ± 4) g·h^(-1)·m-2, P < 0.01]. Yupingfeng granules also significantly down-regulated mRNA and protein expression of AQP3 in the animal models.CONCLUSION: Our findings suggested that Yupingfeng granules could be used in AD treatment. | Sun Zhanxue Wang Jingjun Kong Yuhong Li Nan Jiang Xiaoyuan Cao Ting Jia Yuanning Zhang Yueyue Zhang Yisheng Cheng Jing | 2018 | Journal of Traditional Chinese Medicine2018，38，6： | 6 |
| 16 | Periodically poled lithium niobate whispering gallery mode microcavities on a chip显示文摘In this study, we investigate the fabrication of periodically poled lithium niobate(PPLN) microdisk cavities on a chip. These resonators are fabricated from a PPLN film with a 16 μm poling period on insulator using conventional microfabrication techniques.The quality factor of the PPLN microdisk resonators with a 40-μm radius and a 700-nm thickness is 6.7×10~5. Second harmonic generation(SHG) with an efficiency of 2.2×10^(-6) mW(-1) is demonstrated in the fabricated PPLN microdisks. The nonlinear conversion efficiency could be considerably enhanced by optimizing the period and pattern of the poled structure and by improving the cavity quality factors. | ZhenZhong Hao Li Zhang Ang Gao WenBo Mao XiaoDan Lyu XiaoMei Gao Fang Bo Feng Gao GuoQuan Zhang JingJun Xu | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，11： | 5 |
| 17 | Effects of As on As uptake, speciation, and nutrient uptake by winter wheat (Triticum aestivum L.) under hydroponic conditions显示文摘一个水耕法的实验被进行调查砷的效果(作为) 生长上的应力,营养并且作为在冬小麦(Triticum aestivum L.) 的射击和根的举起,和种形成。冬小麦有高忍耐到作为。在根被积累的大多数,并且一是 4,421 mg/kg 的集中是在 20 mg/L 的答案集中被观察。在根的砷集中比在射击的那些大约 40 100 倍。在冬小麦根和射击的砷作为 As3+ 和 As5+ 种类发生了,尽管 As3+ 是在冬小麦纸巾的主要种类。砷显著地减少了在冬小麦织物的微型元件和宏元素的冬小麦射击和根和影响吸收和运输的生物资源。砷处理显著地在射击增加了全部的镁(Mg ) 和钙(Ca ) 的集中并且从根提高了 Mg 和 Ca 的运输到射击,但是减少钾(K) ,氮(N) ,和在射击和根的磷(P) 集中,特别地 P 的集中。在冬小麦射击的铁,铜,和锌的集中是否定地与有关作为率与 0.93, 0.94,和 0.97 的相关系数(R2 ) ,分别地。 | LIU Quanji HU Chengxiao TAN Qiling SUN Xuecheng SU Jingjun LIANG Yuexiang | 2008 | Journal of Environmental Sciences2008，20，3： | 5 |
| 18 | Photoelastic Visualization of Ultrasound Generated by Pulsed Laser显示文摘We applied the dynamic photoelastic technique to visualize the ultrasound generated in a glass sample by an Nd:YAG pulsed laser.When a laser pulse was incident on the surface of the glass sample covered,by thin layer of black ink,narrow pulses of JongitudinaJ,shear,and surface acoustic waves were seen in the sample.The photoelastic picture also showed that the directivity patterns of ultrasound generated in the present case qualitatively agree with the theoretical prediction for the case of a normal surface-acting force. | ZHANG Shouyu ZHANG Pengzhi SHEN Jianzhong DENG Jingjun YING Chongfu | 1993 | Chinese Physics Letters1993，10，12： | 5 |
| 19 | Experimental Study of Waste Tire Rubber,Wood-Plastic Particles and Shale Ceramsite on the Performance of Self-Compacting Concrete显示文摘In recent decades,the utilization of waste tires,plastic and artificial shale ceramsite as alternative fine aggregate to make self-compacting concrete(SCC)has been recognized as an eco-friendly and sustainable method to manufacture renewable construction materials.In this study,three kinds of recycled aggregates:recycled tire rubber particles,wood-plastic particles,artificial shale ceramsite were used to replace the sand by different volume(5%,10%,20%and 30%),and their effects on the fresh and hardened properties of SCC were investigated.The slump flow and V-funnel tests were conducted to evaluate the fresh properties of modified-SCC mixtures.The hardened properties include 3,7 and 28-day compressive strengths,axial compressive strength,static elastic modulus,and compressive stress-strain behavior at 28 days.The test results showed that the incorporation of these three kinds of alternative aggregates had a negative impact on the fresh properties of SCC.Besides,the 28-day compressive strength and axial compressive strength decreased with the increase of rubber and wood-plastic particles content.In this experiment,all the three kinds of recycled aggregates can improve the ductility and deformability of SCC,and the most excellent performance comes from SCC with recycled rubber particles. | Lei Tian Liuchao Qiu Jingjun Li Yongsen Yang | 2020 | Journal of Renewable Materials2020，8，2： | 5 |
| 20 | Effects of End-Bend and Curved Blades on the Flow Field and Loss of a Compressor Linear Cascade in the Design Condition显示文摘Curved blade and end-bend blade are considered as effective passive control methods for improving the aerodynamic performance of a compressor cascade,and their applicability also needs to be further studied.A highly-loaded compressor linear cascade in the design condition was taken as the research objective in this paper.Numerical simulation was used to study the positive and negative effects of these methods on the flow loss of the cascade by redistributing the vortex structures.Results show that:the curved blade could reduce the flow loss to 2.55%,while the end-bend blade and the end-bend+curved blade increase it to 10.58%and 2.19%,respectively.The positive effect of the curved blade weakens the strength and scale of Concentrated Shedding Vortex(CSV),which accounts for 59.2%of the total flow loss.The negative effect of the end-bend blade exacerbates the low-energy fluid clusters from the end wall and wake into CSV.Finally,the end-bend+curved blade can take their own strengths,but it enhances the twisting motion of Passage Vortex(PV)and CSV,which makes it fail to reduce the flow loss.Therefore,the positive and negative effects of these methods on the flow loss of a compressor cascade are much clearer.In addition,we also predict the potential danger of the end-bend blade in the negative incidence conditions and provides some suggestion for future study. | KAN Xiaoxu WU Wanyang YANG Ling ZHONG Jingjun | 2019 | Journal of Thermal Science2019，28，4： | 4 |
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