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| 1 | Non-invasive means of measuring hepatic fat content显示文摘Hepatic steatosis affects 20% to 30% of the general adult population in the western world. Currently, the technique of choice for determining hepatic fat deposition and the stage of fibrosis is liver biopsy. However, it is an invasive procedure and its use is limited, particularly in children. It may also be subject to sampling error. Non-invasive techniques such as ultrasound, computerised tomography (CT), magnetic resonance imaging (MRI) and proton magnetic resonance spectroscopy (1H MRS) can detect hepatic steatosis, but currently cannot distinguish between simple steatosis and steatohepatitis, or stage the degree of fibrosis accurately. Ultrasound is widely used to detect hepatic steatosis, but its sensitivity is reduced in the morbidly obese and also in those with small amounts of fatty infiltration. It has been used to grade hepatic fat content, but this is subjective. CT can detect hepatic steatosis, but exposes subjects to ionising radiation, thus limiting its use in longitudinal studies and in children. Recently, magnetic resonance (MR) techniques using chemical shift imaging have provided a quantitative assessment of the degree of hepatic fatty infiltration, which correlates well with liver biopsy results in the same patients. Similarly, in vivo 1H MRS is a fast, safe, non-invasive method forthe quantification of intrahepatocellular lipid (IHCL) levels. Both techniques will be useful tools in future longitudinal clinical studies, either in examining the natural history of conditions causing hepatic steatosis (e.g. non-alcoholic fatty liver disease), or in testing new treatments for these conditions. | Sanjeev R Mehta E Louise Thomas Jimmy D Bell Desmond G Johnston Simon D Taylor-Robinson | 2008 | World Journal of Gastroenterology2008，14，22： | 21 |
| 2 | Enhanced photocatalytic activity of solid solution on the degradation of acetone 显示文摘 | JIMMY C Y LIN J KWOK R W M | 1997 | J Photochem Photobiol A:Chem1997，111，： | 1 |
| 3 | The effects of aspirin on gastric mucosal integrity, surface hydrophobieity, and prostaglandin metabolism in cyclooxygenase knockout miee显示文摘 | REBECCA L D JIMMY J R ELIZABETH J D | 2004 | Gastroenterology2004，127，1： | 1 |
| 4 | Methyl bromide fumigation quar- antine treatment for carambolas infested with caribbean fruit fly(Diptera:Tephritedae) 显示文摘 | Guy J H Jimmie R K | 1992 | Journal of Economic Entomology1992，85，4： | 1 |
| 5 | Variability in body morphometric measurements and their application in predicting live body weight of Mubende and small east African goat breeds in Uganda显示文摘 | Jimmy S David M Kugonza R | 2010 | Middle-East Journal of Scientific Research2010，5，2： | 1 |
| 6 | Vacancy engineered ceria nanostructures for protectionfrom radiation-induced cellular damage显示文摘 | Tarnuzzer R W Jimmie C L Swanand P L | 2005 | Nano Lett2005，，5： | 1 |
| 7 | GEPlC-Modelling Wheat Yield and Crop Water Productivity with High Resolution on a Global Scale 显示文摘 | Liu J G Jimmy R W Alexander J B Z | 2007 | Agricultural Systems2007，94，4： | 1 |
| 8 | Winsor I:* ; III:MI microemulsion phase behavior of hydrofluoroethers and fluorocarbon/hydrocarbon catanionic surfactants 显示文摘 | JIMMIE R BARAN Jr | 2001 | J Colloid Interface Sci2001，234，1： | 1 |
| 9 | Intrauterine infection, preterm labor, and cytokines 显示文摘 | Roberto R Offer E Jimmy E | 2005 | Gynecol Invest2005，12，7： | 1 |
| 10 | Underlying characteristics ofpatients harboring highly resistant Acinetobacter baumannii显示文摘 | Siham M Jimmie X Wurts R | 2002 | AmJ lnfect Control2002，30，7： | 1 |
| 11 | Underlying Characteristices of patients harboring highly resistant Acinetobacter baumannii显示文摘 | JIMMIE X WURLS R | 2002 | Am J Infect control2002，30，7： | 1 |
| 12 | Triterpenes from Rhus taitensis显示文摘 | Aysen Yürüker Jimmy Orjala Otto Sticher Topul Rali | 1998 | Phytochemistry1998，，5： | 1 |
| 13 | Following best ginning practices显示文摘 | JIMMY R | 2002 | Cotton Farming2002，，3： | 1 |
| 14 | Normalisation with coherent scatter signal:improvements in the calibration procedure of the ^57 Co-based in vivo XRF bone-Pb measurement显示文摘 | Joanne M Jimmy B David R | 2001 | Applied Radiation Isotopes2001，54，： | 1 |
| 15 | An approach to correlate tandem mass spectral data of peptide with amino acid sequences in a protein database显示文摘 | Jimmy K E Ashley L M John R Y | 1994 | J Am Soc Mass Spectrom1994，5，11： | 1 |
| 16 | How does FDI affect China? evidence from industries and provinces显示文摘 | Jimmy R Jan P V | 2007 | Journal of Comparative Economics2007，35，4： | 1 |
| 17 | Ammonium Ni- trate: Thermal Stability and Explosivity Modifiers显示文摘 | Jimmie C O James L S Evan R | 2002 | Thermochimica Acta2002，84，12： | 1 |
| 18 | Spinosad bait for the Caribbean fruit fly (Diptera: Tephritidae) 显示文摘 | JIMMIE R K MICHAEL K H | 1996 | Florida Entomologist1996，79，4： | 1 |
| 19 | Essential oil composition of the needles of Abies nephrolepis Maxim from China显示文摘 | Li R Jiang Z T Jimmy C Y | 2005 | Flavour and fragrance journal2005，20，： | 1 |
| 20 | Spinosad bait for the Caribbean fruit fly (Diptera:Tephritidae)显示文摘 | Jimmie R K Michael K H | 1996 | Florida Entomologist1996，79，4： | 1 |
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