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| 1 | Benefit of neoadjuvant concurrent chemoradiotherapy for locally advanced perihilar cholangiocarcinoma显示文摘AIM To clarify the role of neoadjuvant concurrent chemoradiotherapy(NACCRT) followed by surgical resection for localized or locally advanced perihilar cholangiocarcinoma(CCA).METHODS We retrospectively reviewed 57 patients who underwent surgical resection with or without NACCRT for perihilar CCA; 12 patients received NACCRT and 45 patients did not received NACCRT. Patients with locally advanced perihilar CCA requiring NACCRT were defined as follows:(1) a mass involving unilateral branches of the portal vein or hepatic artery with insufficient volume of the anticipated remnant lobe; or(2) an infiltrating mass in the main portal vein that was too long for reconstruction, identified at preoperative staging. RESULTS The median disease-free survival(DFS) durations of the neoadjuvant and non-neoadjuvant CCRT groups were26.0 and 15.1 mo, respectively(P = 0.91). The median overall survival(OS) durations of the neoadjuvant and non-neoadjuvant CCRT groups were 32.9 and 27.1 mo, respectively(P = 0.26). The NACCRT group showed a downstaging tendency compared to the non-NACCRT group as compared with the tumor stage confirmed by histological examination after surgery and the tumor stage confirmed by imaging test at the time of diagnosis(P = 0.01). CONCLUSION NACCRT does not prolong DFS and OS in localized or locally advanced perihilar CCA. However, NACCRT may allow tumor downstaging and improve tumor resectability. | Jang Han Jung Hyun Jik Lee Hee Seung Lee Jung Hyun Jo In Rae Cho Moon Jae Chung Jeong Youp Park Seung Woo Park Si Young Song Seungmin Bang | 2017 | World Journal of Gastroenterology2017，23，18： | 21 |
| 2 | Proton-pump inhibitors for prevention of upper gastrointestinal bleeding in patients undergoing dialysis显示文摘AIM:To investigate the preventive effects of low-dose proton-pump inhibitors(PPIs) for upper gastrointestinal bleeding(UGIB) in end-stage renal disease.METHODS:This was a retrospective cohort study that reviewed 544 patients with end-stage renal disease who started dialysis at our center between 2005 and 2013.We examined the incidence of UGIB in 175 patients treated with low-dose PPIs and 369 patients not treated with PPIs(control group).RESULTS:During the study period, 41 patients developed UGIB, a rate of 14.4/1000 person-years.The mean time between the start of dialysis and UGIB events was 26.3 ± 29.6 mo.Bleeding occurred in only two patients in the PPI group(2.5/1000 person-years) and in 39 patients in the control group(19.2/1000 person-years).Kaplan-Meier analysis of cumulative non-bleeding survival showed that the probability of UGIB was significantly lower in the PPI group than in the control group(log-rank test, P < 0.001).Univariate analysis showed that coronary artery disease, PPI use, anti-coagulation, and anti-platelet therapy were associated with UGIB.After adjustments for the potential factors influencing risk of UGIB, PPI use was shown to be significantly beneficial in reducing UGIB compared to the control group(HR = 13.7, 95%CI:1.8-101.6; P = 0.011).CONCLUSION:The use of low-dose PPIs in patients with end-stage renal disease is associated with a low frequency of UGIB. | Young Rim Song Hyung Jik Kim Jwa-Kyung Kim Sung Gyun Kim Sung Eun Kim | 2015 | World Journal of Gastroenterology2015，21，16： | 6 |
| 3 | Crosstalk between platelet-derived growth factor-induced Nox4 activation and MUC8 gene overexpression in human airway epithelial cells显示文摘 | Hyun Jik Kim Chang-Hoon Kim Ji-Hwan Ryu Jung Hee Joo Sang-Nam Lee Min-Ji Kim Jeung-Gweon Lee Yun Soo Bae Joo-Heon Yoon | 2011 | Free Radical Biology and Medicine2011，，9： | 2 |
| 4 | Credit Markets with Differences in Abilities: Education, Distribution, and Growth 显示文摘 | Gregorio Jos6 De Se -Jik Kim | 2000 | International Economic Review2000，，41： | 1 |
| 5 | Position-invariant Neural Network for Digital Pavement Crack Analysis显示文摘 | Lee Byoung Jik | 2004 | Computer-Aided Civil and Infrastructure Engineering2004，19，3： | 1 |
| 6 | An Exploratory Study on the Quality of Life of older Chinese People Living alone in Hong Kong显示文摘 | Jik Joen Lee | 2005 | Social Indicators Research2005，，1： | 1 |
| 7 | Inactivating mutations of caspase-8 gene in colorectal carcinomas显示文摘 | Hong Sug Kim Jong Woo Lee Young Hwa Soung Won Sang Park Su Young Kim Jong Heun Lee Jik Young Park Youg Gu Cho Chang Jae Kim Seong Whan Jeong Suk Woo Nam Sang Ho Kim Jung Young Lee Nam Jin Yoo Sug Hyung Lee | 2003 | Gastroenterology2003，，3： | 1 |
| 8 | Fabrication of silicon field emitters by forming porous silicon 显示文摘 | Kim Donghwan Kwon Sang Jik Lee Jong Duk | 1996 | Vac Sci Technol B1996，14，3： | 1 |
| 9 | Structural Change ot the Melt Spun Al--10Ni--5Y by the Addition of 1% Sr显示文摘 | Taek -Soo Kim Soo -Jik Hong Jong - Hyeon Lee Kyong - Whan Kim | 2001 | Materials Science and Engineering2001，311，： | 1 |
| 10 | Structural characterization of sol- gel derived MgO thin film on Si suhstrate显示文摘 | Jong-Gul Yoon Young Jik Kwag | 1997 | J Korean Phys Soc1997，31，4： | 1 |
| 11 | Development of a subcritical fluid extraction and GC - MS validation method for polychlorinated biphenyls (PCBs) in marine samples显示文摘 | JiK FengX Liu K Han Y Xue Y Xue C | 2013 | Journal of Chromatography B2013，923，： | 1 |
| 12 | Mutations of β‐catenin and AXIN I genes are a late event in human hepatocellular carcinogenesis显示文摘 | Jik YoungPark Won SangPark Suk WooNam Su YoungKim Sug HyungLee Nam JinYoo Jung YoungLee Cheol KeunPark | 2005 | Liver International2005，，1： | 1 |
| 13 | Microstructural Behavior of Rapidly Solidified and Extruded A1 -- 14wt%Ni -- 14wt%Mm (Mm,Misch Metal) Alloy Powders显示文摘 | Soon Jik Hong Taek - Soo Kim Hyoung Seop Kim Won Tae Kim Byong Sun Chun | 1999 | Materials Science and Engineering A1999，271，： | 1 |
| 14 | Analysis of re- current mitral regurgitation after mitral valve repair 显示文摘 | Hong Ju shin Yong Jik Lee Suk Jung choo | 2005 | Asian Car- diovasc Thorac Ann2005，13，3： | 1 |
| 15 | Position-invariant neural network for digital pavement crack analysis 显示文摘 | Lee Byoung Jik | 2004 | Computer-Aided Civil and Infrastructure Engineering2004，19，3： | 1 |
| 16 | Nuclear factor kappa B:important transcription factor and therapeutic target显示文摘 | Lee JIK Pharmd D Gilbert J | 1998 | J Clin Pharmacol1998，38，： | 1 |
| 17 | Participation of the chaperone HscT0 in the trafficking and functional expres sionof ASIC2 in glioma cells显示文摘 | Vila Carriles WH Zhou ZH Bubien JIK | 2007 | J Biol Chem2007，282，34： | 1 |
| 18 | P53opensthemitochondrialpermeabilitytransitionporetotriggernecroGsis显示文摘 | VASEVAAV MARCHENKOND JIK etal | 2012 | Cell2012，149，7： | 1 |
| 19 | Neclear factor kappaB: Important transcription factor and therapeutic target显示文摘 | Pharmd D Gilbert J | 1998 | J Clin Pharmacol1998，38，11： | 1 |
| 20 | Performance Manage- ment and Trust in Supervisors显示文摘 | Yoon Jik Cho Jung Wook Lee | 2011 | Review of Public Person- nel Administration2011，，3： | 1 |
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