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| 1 | Transient receptor potential vanilloid 4-dependent calcium influx and ATP release in mouse and rat gastric epithelia显示文摘AIM: To explore the expression of transient receptor potential vanilloid 4(TRPV4) and its physiological meaning in mouse and rat gastric epithelia. METHODS: RT-PCR and immunochemistry were used to detect TRPV4 m RNA and protein expression in mouse stomach and a rat normal gastric epithelial cell line(RGE1-01), while Ca2+-imaging and electrophysiology were used to evaluate TRPV4 channel activity. ATP release was measured by a luciferin-luciferase assay. Gastric emptying was also compared between WT and TRPV4 knockout mice. RESULTS: TRPV4 m RNA and protein were detected in mouse tissues and RGE1-01 cells. A TRPV4-specific agonist(GSK1016790A) increased intracellular Ca2+ concentrations and/or evoked TRPV4-like current activities in WT mouse gastric epithelial cells andRGE1-01 cells, but not TRPV4 KO cells. GSK1016790 A or mechanical stimuli induced ATP release from RGE1-01 cells while TRPV4 knockout mice displayed delayed gastric emptying in vivo. CONCLUSION: TRPV4 is expressed in mouse and rat gastric epithelium and contributes to ATP release and gastric emptying. | Hiroshi Mihara Nobuhiro Suzuki Ammar Abdullkader Boudaka Jibran Sualeh Muhammad Makoto Tominaga Yoshiaki Tabuchi Toshiro Sugiyama | 2016 | World Journal of Gastroenterology2016，22，24： | 5 |
| 2 | Chromosome-scale scaffolding of the black raspberry (Rubus occidentalis L.) genome based on chromatin interaction data显示文摘Black raspberry(Rubus occidentalis L.)is a niche fruit crop valued for its flavor and potential health benefits.The improvement of fruit and cane characteristics via molecular breeding technologies has been hindered by the lack of a high-quality reference genome.The recently released draft genome for black raspberry(ORUS 4115-3)lacks assembly of scaffolds to chromosome scale.We used high-throughput chromatin conformation capture(Hi-C)and Proximity-Guided Assembly(PGA)to cluster and order 9650 out of 11,936 contigs of this draft genome assembly into seven pseudo-chromosomes.The seven pseudo-chromosomes cover~97.2%of the total contig length(~223.8 Mb).Locating existing genetic markers on the physical map resolved multiple discrepancies in marker order on the genetic map.Centromeric regions were inferred from recombination frequencies of genetic markers,alignment of 303 bp centromeric sequence with the PGA,and heat map showing the physical contact matrix over the entire genome.We demonstrate a high degree of synteny between each of the seven chromosomes of black raspberry and a high-quality reference genome for strawberry(Fragaria vesca L.)assembled using only PacBio long-read sequences.We conclude that PGA is a cost-effective and rapid method of generating chromosome-scale assemblies from Illumina short-read sequencing data. | Rubina Jibran Helge Dzierzon Nahla Bassil Jill M.Bushakra Patrick P.Edger Shawn Sullivan Chad E.Finn Michael Dossett Kelly J.Vining Robert VanBuren Todd C.Mockler Ivan Liachko Kevin M.Davies Toshi M.Foster David Chagné | 2018 | Horticulture Research2018，5，1： | 4 |
| 3 | Anti-inflammatory and cytoprotective effects of selected Pakistani medicinal plants in Helicobacter pylori -infected gastric epithelial cells显示文摘 | Syed Faisal Zaidi Jibran Sualeh Muhammad Saeeda Shahryar Khan Usmanghani Anwarul-Hassan Gilani Wasim Jafri Toshiro Sugiyama | 2012 | Journal of Ethnopharmacology2012，，1： | 3 |
| 4 | Pembrolizumab-emerging treatment of pulmonary sarcomatoid carcinoma: A case report显示文摘BACKGROUND Few studies have addressed the efficacy of pembrolizumab in pulmonary sarcomatoid carcinoma(PSC),a rare,previously rapidly fatal subtype of nonsmall-cell lung cancer.CASE SUMMARY We report the case of a 69-year-old man presented with respiratory distress caused by a large left upper lung lobe mass diagnosed as PSC with programmed death-ligand 1 expressed on more than 50 percent of tumor cells.The patient was started on pembrolizumab and,after 5 cycles,there was a more than 80 percent decrease in the size of the tumor mass.Further decrease was seen at the end of 10 cycles.The patient has been tolerating pembrolizumab well,with no limiting side-effects.Fourteen months after first coming into the hospital,he remains asymptomatic.CONCLUSION Pembrolizumab appears as a viable emerging treatment for PSC. | Emanuela Cimpeanu Jibran Ahmed Wahib Zafar Adreana DeMarinis Svetoslav S Bardarov Shamim Salman Dennis Bloomfield | 2020 | World Journal of Clinical Cases2020，8，1： | 2 |
| 5 | 膜富集-可见漫反射光谱法测定池塘水和维生素B_(12)药片中痕量钴显示文摘1-(2-吡啶偶氮)-2-萘酚与钴离子生成暗绿色的络合物,反应后将其过滤到膜上,测得膜表面漫反射光谱,据此提出了膜富集-可见漫反射光谱法测定池塘水和维生素B12药片中痕量钴的方法。钴的质量浓度在0.2~3.0μg·L-1和3.0~10.0μg·L-1范围内与其吸光度呈线性关系,检出限(3s/k)为0.093μg·L-1。方法用于池塘水和维生素B12药片的分析,加标回收率在96.7%~105%之间,测定值的相对标准偏差在1.4%~2.9%之间。 | 朱碧琳 胡慧廉 IQBAL Jibran 王蕾 张晓芳 张磊 杨伟宏 吴婷 杜一平 | 2015 | 理化检验(化学分册)2015，51，2： | 2 |
| 6 | Multi-Level Knowledge Engineering Approach for Mapping Implicit Aspects to Explicit Aspects显示文摘Aspect’s extraction is a critical task in aspect-based sentiment analysis,including explicit and implicit aspects identification.While extensive research has identified explicit aspects,little effort has been put forward on implicit aspects extraction due to the complexity of the problem.Moreover,existing research on implicit aspect identification is widely carried out on product reviews targeting specific aspects while neglecting sentences’dependency problems.Therefore,in this paper,a multi-level knowledge engineering approach for identifying implicit movie aspects is proposed.The proposed method first identifies explicit aspects using a variant of BiLSTM and CRF(Bidirectional Long Short Memory-Conditional Random Field),which serve as a memory to process dependent sentences to infer implicit aspects.It can identify implicit aspects from four types of sentences,including independent and three types of dependent sentences.The study is evaluated on a largemovie reviews dataset with 50k examples.The experimental results showed that the explicit aspect identification method achieved 89%F1-score and implicit aspect extraction methods achieved 76%F1-score.In addition,the proposed approach also performs better than the state-of-the-art techniques(NMFIAD andML-KB+)on the product review dataset,where it achieved 93%precision,92%recall,and 93%F1-score. | Jibran Mir Azhar Mahmood Shaheen Khatoon | 2022 | Computers, Materials & Continua2022，，2： | 1 |
| 7 | Desipramine enhances the ability of risperidone to decrease alcohol intake in the Syrian golden hamster显示文摘 | Danielle Gulick David T. Chau Jibran Y. Khokhar Ree Dawson Alan I. Green | 2014 | Psychiatry Research2014，，： | 1 |
| 8 | Key wavelengths selection from near infrared spectra using Monte Carlo sampling–recursive partial least squares显示文摘 | Mingjin Zhang Shizhi Zhang Jibran Iqbal | 2013 | Chemometrics and Intelligent Laboratory Systems2013，，： | 1 |
| 9 | Study on difference between epidermis, phloem and xylem of Radix Ginseng with near-infrared and infrared spectroscopy coupled with principal component analysis显示文摘 | Yanhong Wu Yi Zheng Qingqing Li Jibran Iqbal Lingyi Zhang Weibing Zhang Yiping Du | 2010 | Vibrational Spectroscopy2010，，2： | 1 |
| 10 | Anti-inflammatory and cytoprotective effects of selected Pakistani medicinal plants in Helicobacter pylori-infected gastric epithelial cells显示文摘 | Syed Faisal Zaidi Jibran Sualeh Muhammad Saeeda Shahryar | 2012 | Journal of Ethnopharmacology2012，141，1： | 1 |
| 11 | Rapid determination of illegal additives chrysoidin and malachite green by surface-enhanced Raman scattering with silanized support based substrate显示文摘This paper reports accurate use of silanized support based substrate for surface-enhanced Raman spectroscopy(SERS) determination of illegal additives chrysoidin and malachite green. Detection of these illegal additives is very meaningful and the developed method meets this objective in a simple, rapid and cost effective way. Detection limits for chrysoidin and malachite green in aqueous solutions reached0.001 mg/L and 0.0001 mg/L respectively. Linear relationship between the Raman intensities and chrysoidin concentrations in range of 0.001-0.05 mg/L was found with regression coefficient(R) of 0.994.To investigate the practical application performance of the method, the substrate was applied to detect chrysoidin in Sprite at 0.01 mg/L and malachite green in fish pond water at 0.0001 mg/L. The SERS method could be an alternative approach for monitoring illegal additives and toxic harmful substances. | Han Zhang Lin Sun Yuan Zhang Yan Kang Huilian Hu Jibran Iqbal Yiping Du | 2018 | Chinese Chemical Letters2018，29，6： | 0 |
| 12 | Multiple quantitative trait loci contribute to resistance to bacterial canker incited by Pseudomonas syringae pv.actinidiae in kiwifruit(Actinidia chinensis)显示文摘Pseudomonas syringae pv.actinidiae(Psa)biovar 3,a virulent,canker-inducing pathogen is an economic threat to the kiwifruit(Actinidia spp.)industry worldwide.The commercially grown diploid(2×)A.chinensis var.chinensis is more susceptible to Psa than tetraploid and hexaploid kiwifruit.However information on the genetic loci modulating Psa resistance in kiwifruit is not available.Here we report mapping of quantitative trait loci(QTLs)regulating resistance to Psa in a diploid kiwifruit population,derived from a cross between an elite Psa-susceptible‘Hort16A’and a resistant male breeding parent P1.Using high-density genetic maps and intensive phenotyping,we identified a single QTL for Psa resistance on Linkage Group(LG)27 of‘Hort16A’revealing 16–19%phenotypic variance and candidate alleles for susceptibility and resistance at this loci.In addition,six minor QTLs were identified in P1 on distinct LGs,exerting 4–9%variance.Resistance in the F1 population is improved by additive effects from‘Hort16A’and P1 QTLs providing evidence that divergent genetic pathways interact to combat the virulent Psa strain.Two different bioassays further identified new QTLs for tissue-specific responses to Psa.The genetic marker at LG27 QTL was further verified for association with Psa resistance in diploid Actinidia chinensis populations.Transcriptome analysis of Psa-resistant and susceptible genotypes in field revealed hallmarks of basal defense and provided candidate RNA-biomarkers for screening for Psa resistance in greenhouse conditions. | Jibran Tahir Stephen Hoyte Heather Bassett Cyril Brendolise Abhishek Chatterjee Kerry Templeton Cecilia Deng Ross Crowhurst Mirco Montefiori Ed Morgan Andrew Wotton Keith Funnell Claudia Wiedow Mareike Knaebel Duncan Hedderley Joel Vanneste John McCallum Kirsten Hoeata Amardeep Nath David Chagné Luis Gea Susan E.Gardiner | 2019 | Horticulture Research2019，6，1： | 0 |
| 13 | An Efficient Method for Underwater Video Summarization and Object Detection Using YoLoV3显示文摘Currently,worldwide industries and communities are concerned with building,expanding,and exploring the assets and resources found in the oceans and seas.More precisely,to analyze a stock,archaeology,and surveillance,sev-eral cameras are installed underseas to collect videos.However,on the other hand,these large size videos require a lot of time and memory for their processing to extract relevant information.Hence,to automate this manual procedure of video assessment,an accurate and efficient automated system is a greater necessity.From this perspective,we intend to present a complete framework solution for the task of video summarization and object detection in underwater videos.We employed a perceived motion energy(PME)method tofirst extract the keyframes followed by an object detection model approach namely YoloV3 to perform object detection in underwater videos.The issues of blurriness and low contrast in underwater images are also taken into account in the presented approach by applying the image enhancement method.Furthermore,the suggested framework of underwater video summarization and object detection has been evaluated on a publicly available brackish dataset.It is observed that the proposed framework shows good performance and hence ultimately assists several marine researchers or scientists related to thefield of underwater archaeology,stock assessment,and surveillance. | Mubashir Javaid Muazzam Maqsood Farhan Aadil Jibran Safdar Yongsung Kim | 2023 | Intelligent Automation & Soft Computing2023，，2： | 0 |
| 14 | Ins and outs of Helicobacter pylori association with autoimmune rheumatic diseases显示文摘Helicobacter pylori(H.pylori) infection is widely prevalent throughout worldwide.H.pylori manage a long-term survival in hostile environment of human stomach leading to peptic ulcer diseases and gastric cancer.But mostly infected person remains asymptomatic.Its chronic interaction with immune system makes H.pylori as an attractive candidate for the researchers to study its association with autoimmune diseases.This article presents a review of the literature on the association of H.pylori infection in selective autoimmune rheumatic diseases(RD).The authors used Me SH terms 'Helicobacter pylori ' with 'rheumatoid arthritis,' 'systemic lupus erythematosus,' or 'fibromyalgia' to search Pub Med database.All relevant studies identified were included.Despite extensive medical advancement many questions on role of H.pylori infection in autoimmune RD still remain unanswered.Further studies are therefore needed to address the role of H.pylori in pathogenesis of RD. | Jibran Sualeh Muhammad Syed Faisal Zaidi Muhammad Ishaq | 2015 | World Journal of Rheumatology2015，5，2： | 0 |
| 15 | A Triplet-Branch Convolutional Neural Network for Part-Based Gait Recognition显示文摘Intelligent vision-based surveillance systems are designed to deal with the gigantic volume of videos captured in a particular environment to perform the interpretation of scenes in form of detection,tracking,monitoring,behavioral analysis,and retrievals.In addition to that,another evolving way of surveillance systems in a particular environment is human gait-based surveillance.In the existing research,several methodological frameworks are designed to use deep learning and traditional methods,nevertheless,the accuracies of these methods drop substantially when they are subjected to covariate conditions.These covariate variables disrupt the gait features and hence the recognition of subjects becomes difficult.To handle these issues,a region-based triplet-branch Convolutional Neural Network(CNN)is proposed in this research that is focused on different parts of the human Gait Energy Image(GEI)including the head,legs,and body separately to classify the subjects,and later on,the final identification of subjects is decided by probability-based majority voting criteria.Moreover,to enhance the feature extraction and draw the discriminative features,we have added soft attention layers on each branch to generate the soft attention maps.The proposed model is validated on the CASIA-B database and findings indicate that part-based learning through triplet-branch CNN shows good performance of 72.98%under covariate conditions as well as also outperforms single-branch CNN models. | Sang-Soo Yeo Seungmin Rho Hyungjoon Kim Jibran Safdar Umar Zia Mehr Yahya Durrani | 2023 | Computer Systems Science & Engineering2023，47，11： | 0 |
| 16 | Study on properties of tantalum-doped La_(2)Ti_(2)O_(7) ferroelectric ceramics显示文摘A series of ceramics with a general formula,La_(2)Ti_(2-x)Ta_(x)O_(7),in which x=0.05;0.1;0.2;and 0.3,were prepared by Spark Plasma Sintering(SPS).Effects of tantalum substitution for titanium on the structure,dielectric,and piezoelectric properties were studied.Results revealed that the structure changed gradually from 4-layer to 3-layer due to the higher valence of Ta.The solid solution limit of tantalum in La_(2)Ti_(2)O_(7)lattice was in the proximity of x=0.2.The ferroelectric Curie temperature(Tc)decreased with increasing tantalum doping content.dc resistivity reached a maximum value at x=0.2 with a value of~1.0×10^(8)Ωcm at 600℃.The influence of texture on the piezoelectric properties of La_(2)Ti_(2-x)Ta_(x)O_(7)ceramics was also investigated.A maximum d_(33)value~2:1 pC/N was obtained at x=0.2. | Chunchun Li Jibran Khaliq Huanpo Ning Xiaoyong Wei Haixue Yan Michael JReece | 2015 | Journal of Advanced Dielectrics2015，5，1： | 0 |
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