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您的检索式：作者名="Jianming LANG"
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| 1 | A comparison of food habits and prey preferences of Amur tiger(Panthera tigris altaica)at the southwest Primorskii Krai in Russia and Hunchun in China显示文摘A small,isolated Amur tiger population ranges across the southwest Primorskii Krai region in Russia and Hunchun region in China.Many individuals,with“dual nationality,”cross the border frequently.Formulating effective conservation strategies requires a clear understanding of tiger food requirements in both countries.While the diets of tigers ranging in Russia is clearly understood,little is known of the tigers’feeding habits in China..We used scat analysis combined with data on the abundance of 4 prey species to examine Amur tiger diet and prey preferences in Hunchun.We examined 53 tiger scat samples from 2011 to 2016 and found that tigers preyed on 12 species(11 species in winter),4 of which were domestic animals with 33.58%biomass contribution;this was the first record of Amur tigers eating lynx in this area.Tigers showed a strong preference for wild boar(Jacobs index:+0.849),which were also the most frequently consumed prey,and a strong avoidance of roe deer(Jacobs index:–0.693).On the Russian side,domestic animals(just dog)were rarely found in tiger scat,and tigers did not show strong avoidance of roe deer,but of sika deer.We also found red deer footprints during winter surveys and that tigers ate red deer on the Chinese side,while there was no record of red deer feeding on the Russian side.Reducing or eliminating human disturbance,such as grazing,is essential to recovering tiger prey and habitat in this area and the Sino–Russian joint ungulate annual survey is indispensable for prey estimates of this small,isolated Amur tiger population. | Jiayin GU Lan YU Yan HUA Yao NING Bao HENG Jinzhe QI Zexv LONG Mingyuan YAO Chong HUANG Zhilin LI Jianming LANG Guangshun JIANG Jianzhang MA | 2018 | Integrative Zoology2018，13，5： | 1 |
| 2 | Salicylic acid sensitizes cervical cancer cells to radiotherapy by activating AMPK/TSC2/mTOR pathway显示文摘Objective:To investigate the radio-sensitizing effect of salicylic acid(SA)on human cervical cancer cells and its potential molecular mechanism.Methods:Cervical cancer cells were treated with SA and ionizing radiation.The expression ofγ-H2AX was evaluated by immunofluorescence(IF)assay.Cell cycle and apoptosis were analyzed by flow cytometry.Western blot was performed to detect the protein level of AMPK/TSC2/mTOR pathway.Results:SA inhibited basal proliferation of cervical cancer cells in a dose and time dependent manner.In addition,SA increased radiation-induced DNA damage,promoted apoptosis,triggered a redistribution of cell cycle from G2-M phase to G1-S phase of cervical cancer cells,and hence increased cell sensitivity to radiation.Moreover,SA treatment elevated the expression levels of p-AMPKα(t=3.996,P<0.05)and p-TSC2(t=5.308,P<0.05),whereas the level of p-mTOR(t=10.160,P<0.05)was significantly decreased.Conclusion:SA enhances the radiosensitivity of cervical cancer cells by targeting AMPK/TSC2/mTOR signaling pathway,and might serve as a promising therapeutic strategy to improve the efficacy of radiotherapy for cervical cancer. | Shun Lu Wenjing Ye Jie Zhou Guangming Yi Jianming Huang Siyao Deng Minglun Li Yimin Li Yanqiong Song Jiayu Zhang Lichun Wei Guiquan Zhu Jinyi Lang | 2022 | Radiation Medicine and Protection2022，3，1： | 0 |
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