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| 1 | Effects of Sc, Zr and Tion the microstructure and properties of Al alloys with high Mg content显示文摘The effects of trace Sc, Zr, and Ti on the microstructure and hardness of Al alloys with high Mg content (Al-6Mg, Al-8Mg, and Al-10Mg) were studied by optical microscope, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and Brinell hardness. The grain size of the ascast alloys was refined by the addition of Sc and Zr, and it was further refined by the addition of Ti. With the same contents of Sc, Zr, and Ti, an increase in Mg content was beneficial to the refinement due to the solution of Mg into α-Al. The refined microstructures of the as-cast alloys were favorable for Brinell hardness. Addition of Sc, Zr, and Ti to the Al-10Mg alloy results in the improvement of peak hardness and it is about 45% higher than that of the Al-10Mg alloy, which is due to fine precipitations of Al3(Sc1-xZrx), Al3(Sc1-xTix), and Al3(Sc1-x-yZrxTiy). | WANG Xu CHEN Guoqin LI Bing WU Lianmei JIANG Darning | 2010 | Rare Metals2010，29，1： | 18 |
| 2 | MicroRNA-150 aggravates H2O2-induced cardiac myocyte injury by down-regulating c-myb gene显示文摘MicroRNAs (miRNAs ) 是经由降级或他们的目标基因的翻译抑制在 post-transcriptional 规定起一个重要作用的非编码的 RNA 的一个班。MicroRNA-150 (miR-150 ) 在调整 B 和 T 淋巴细胞的发展起一个重要作用。尽管 miR-150 的 dysregulation 在人的心肌的梗塞被证实,很少响应反应的氧种类(ROS ) 关于 miR-150 的生物功能被知道在心脏的 myocytes 的调停的基因规定。用量的即时反向的抄写聚合酶链反应,我们证明 miR-150 的水平在在有氢过氧化物(H2O2 ) 的治疗以后的心脏的 myocytes 是起来调整的。在调停 H2O2 的基因规定识别 miR-150 的潜在的角色,我们调制了表示用 miR-150 禁止者的 miR-150 和 miR-150 模仿。结果证明 miR-150 的那 silencing 表情减少了导致 H2O2 的心脏的房间死亡和 apoptosis。在淋巴细胞, c-myb 是 miR-150 的一个直接目标。在心脏的 myocytes,我们发现 c-myb 也涉及 miR-150-mediated 导致 H2O2 的心脏的房间死亡。这些结果建议 miR-150 在心脏的 myocytes 参予调停 H2O2 的基因规定和功能的调整。MiR-150 可以在与 ROS 有关的心疾病起一个必要作用,例如心脏的肥大,心失败,心肌的梗塞,和心肌的 ischemia/reperfusion 损害。 | Xuebiao Li Minjian Kong Darning Jiang Jianfang Qian Qunjun Duan Aiqiang Dong | 2013 | Acta Biochimica et Biophysica Sinica2013，45，9： | 3 |
| 3 | Expression, purification of a synthetic fuse-protein-TSF from PF4 and TSP1 fragments and its effect on angio-genesis and tumor growth显示文摘Sequences encoding PF4 (58-70) and TSP1 (429-459) were linked to yield a single gene TSF which encodes the fuse-protein of TSF. The gene was cloned into a pGEX-2T expression vector to generate a protein GST-TSF, which was strongly expressed in E. coli. The purified GST-TSF was degraded with thrombin to generate the protein TSF. With the methods of MTT and wound repair assay, the effects of TSF on the proliferation and migration of EC were detected, respectively. The results showed that TSF significantly suppressed BAEC proliferation and migration in a dose-dependent manner. The fuse protein GST-TSF, and the peptides PF4 (58-70) and TSP1 (429-459) also inhibited BAEC proliferation and migration, respectively, but their inhibition rates were not as high as TSF. Using the CAM assay, it was shown that TSF, GST-TSF, PF4 (58-70) and TSP1 (429-459) inhibited angiogenesis in chick CAM potentially, the effect of TSF was the highest. In vivo, the growth of Lewis lung carcinoma was potently inhibited by TSF | SHEN Xianrong JI Dongmei HU Youqing JIA Fuxing DENG Xinxian WANG Ling CHU Zhiyong JIANG Dingwen LEI Chengxiang HUANG Jiansheng HU Xinran REN Darning | 2001 | Chinese Science Bulletin2001，46，24： | 2 |
| 4 | Effect of Mg content on the mechanical properties and microstructure of Gf/Al composite显示文摘 | WANG Xu JIANG Darning WU Gaohui | 2008 | Materials Science and Engineering A2008，497，12： | 1 |
| 5 | Adhering wear mechanism of cemented carbide cutter in the intervallic cutting of stainless steel显示文摘 | Fenglian Sun Zhenjia Li Darning Jiang | 1998 | Wear1998，214，： | 1 |
| 6 | A (1 + e)- approximation algorithm for sorting by short block moves 显示文摘 | Jiang Haitao Zhu Darning Zhu Binhai | 2012 | Theoretical Computer Science2012，439，： | 1 |
| 7 | Electrospinning of threedimensional nanofibrous tubes with controllable architectures显示文摘 | Zhang Darning Chang Jiang | 2008 | Nano Lett2008，8，10： | 1 |
| 8 | Genetic studies of A2M and BACEI genes in Chinese Han Alzheimer's disease patients显示文摘 | Lei Cai Guomei Tang Lishan Chen Bosheng Zhang Sanduo Jiang Darning Ren | 2005 | 中国生物学文摘2005，19，11： | 1 |
| 9 | Characterization of precipitation microstructure and properties of 7150 aluminium alloy 显示文摘 | Fan Xigang Jiang Darning Meng Qingchang | 2006 | Materials Science and Engineering2006，427，： | 1 |
| 10 | The microstructural evolution of an Al-Zn-Mg-Cu alloy during homogenization显示文摘 | Xigang Fan Darning Jiang Qingchang Meng Zhong Li | 2006 | Materials Letters2006，，： | 1 |
| 11 | Superplasticity in an Aluminum Alloy 6061/Al_2O_3p Composite显示文摘The superplasticity of an Al203p/6061Al composite, fabricated by powder metallurgy techniques, has been investigated. Instead of any special thermomechanical processing or hot rolling, simple hot extrusion has been employed to obtain a fine grained structure before superplastic testing. Superplastic tensile tests were performed at strain rates ranging from 10-2 to 10-4 s-1 and at temperatures from 833 to 893 K. A maximum elongation of 200% was achieved at a temperature of 853 K and an initial strain rate of 1.67×103 s-1. The highest value obtained for the strain rate sensitivity index (in) was 0.32. Differential scanning calorimeter was used to ascertain the possibility of any partial melting in the vicinity of optimum superplastic temperature. These results suggested that no liquid phase existed where maximum elongation was achieved and deformation took place entirely in the solid state. | Lihong HAN, Jitai NIU and Darning JIANG The National Key Laboratory of Advanced Welding Production Technology, Harbin Institute of Technology, Harbin 150001, China Tsunernichi Imai National Industrial Research | 2001 | Journal of Materials Science & Technology2001，17，6： | 0 |
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