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| 1 | Biomarkers of aging显示文摘Aging biomarkers are a combination of biological parameters to(i)assess age-related changes,(ii)track the physiological aging process,and(iii)predict the transition into a pathological status.Although a broad spectrum of aging biomarkers has been developed,their potential uses and limitations remain poorly characterized.An immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research:How old are we?Why do we get old?And how can we age slower?This review aims to address this need.Here,we summarize our current knowledge of biomarkers developed for cellular,organ,and organismal levels of aging,comprising six pillars:physiological characteristics,medical imaging,histological features,cellular alterations,molecular changes,and secretory factors.To fulfill all these requisites,we propose that aging biomarkers should qualify for being specific,systemic,and clinically relevant. | Aging Biomarker Consortium Hainan Bao Jiani Cao Mengting Chen Min Chen Wei Chen Xiao Chen Yanhao Chen Yu Chen Yutian Chen Zhiyang Chen Jagadish K Chhetri Yingjie Ding Junlin Feng Jun Guo Mengmeng Guo Chuting He Yujuan Jia Haiping Jiang Ying Jing Dingfeng Li Jiaming Li Jingyi Li Qinhao Liang Rui Liang Feng Liu Xiaoqian Liu Zuojun Liu Oscar Junhong Luo Jianwei Lv Jingyi Ma Kehang Mao Jiawei Nie Xinhua Qiao Xinpei Sun Xiaoqiang Tang Jianfang Wang Qiaoran Wang Siyuan Wang Xuan Wang Yaning Wang Yuhan Wang Rimo Wu Kai Xia Fu-Hui Xiao Lingyan Xu Yingying Xu Haoteng Yan Liang Yang Ruici Yang Yuanxin Yang Yilin Ying Le Zhang Weiwei Zhang Wenwan Zhang Xing Zhang Zhuo Zhang Min Zhou Rui Zhou Qingchen Zhu Zhengmao Zhu Feng Cao Zhongwei Cao Piu Chan Chang Chen Guobing Chen Hou-Zao Chen Jun Chen Weimin Ci Bi-Sen Ding Qiurong Ding Feng Gao Jing-Dong JHan Kai Huang Zhenyu Ju Qing-Peng Kong Ji Li Jian Li Xin Li Baohua Liu Feng Liu Lin Liu Qiang Liu Qiang Liu Xingguo Liu Yong Liu Xianghang Luo Shuai Ma Xinran Ma Zhiyong Mao Jing Nie Yaojin Peng Jing Qu Jie Ren Ruibao Ren Moshi Song Zhou Songyang Yi Eve Sun Yu Sun Mei Tian Shusen Wang Si Wang Xia Wang Xiaoning Wang Yan-Jiang Wang Yunfang Wang Catherine CL Wong Andy Peng Xiang Yichuan Xiao Zhengwei Xie Daichao Xu Jing Ye Rui Yue Cuntai Zhang Hongbo Zhang Liang Zhang Weiqi Zhang Yong Zhang Yun-Wu Zhang Zhuohua Zhang Tongbiao Zhao Yuzheng Zhao Dahai Zhu Weiguo Zou Gang Pei Guang-Hui Liu | 2023 | Science China(Life Sciences)2023，66，5： | 2 |
| 2 | Nigral degeneration with inclusionbody formation and behavioral changes in rats after proteasomal inhibition显示文摘 | Chaoshi Niu Jiaming Mei Qi Pan | 2009 | Stereotact Funct Neurosurg2009，87，： | 1 |
| 3 | Synthesis and magnetic properties of shuriken-like nickel nanoparticles显示文摘Shuriken-like nickel nanoparticles were successfully synthesized by a thermal decomposition method at200?C with Nickel(II) acetylacetonate(Ni(acac)2) as the precursor and oleylamine(OAm) as the solvent and reductant,respectively.The phase structures,morphologies and sizes,and magnetic properties of the as-synthesized nickel products were characterized in detail by using X-ray diffraction(XRD),X-ray photoelectron spectroscopy(XPS),field emission-scanning electron microscopy(FE-SEM),transmission electron microscopy(TEM),high-resolution transmission electron microscopy(HRTEM) and vibrating sample magnetometer(VSM).Some key reaction parameters,such as the reaction time,reaction temperature and surfactants,have important influence on the morphology of the final products.XRD pattern indicated that the products are well-crystallized face-centered cubic(fcc) nickel phase.SEM images demonstrated that the nickel nanoparticles are shuriken-like morphology with average size around150 nm.The mechanism of shuriken-like Ni nanoparticles(NPs) is proposed.The magnetic hysteresis loops of shuriken-like and spherical nickel products illustrated the ferromagnetic nature at 300 K,indicating its potential applications in magnetic storage. | Shengqing Liu Jiaming Mei Chen Zhang Jianchao Zhang Rongrong Shi | 2018 | Journal of Materials Science & Technology2018，34，5： | 1 |
| 4 | Nigral degeneration with inclusion body formation and behavioral changes in rats after proteasomal inhibition显示文摘 | Chaoshi Niu Jiaming Mei Qi Pan | 2009 | Stereo - tact Funct Neurosurg2009，87，2： | 1 |
| 5 | Gambogenic acid induced mitochondrial-dependent apoptosis and referred to Phospho-Erk1/2 and Phospho-p38 MAPK in human hepatoma HepG2 cells显示文摘 | Fenggen Yan Mei Wang Jiaming Li Hui Cheng Jingjing Su Xiaoshan Wang Haiyun Wu Lunzhu Xia Xiaoxiang Li Hebron C. Chang Qinglin Li | 2011 | Environmental Toxicology and Pharmacology2011，，2： | 1 |
| 6 | Brain gliomas Biological characteristics and correlation with the status of adjacent corticospinal tracts显示文摘Malignant behaviors of brain gliomas include proliferation and infiltration. It remains unclear which behavior influences the status of adjacent corticospinal tracts. Diffusion tensor imaging can show the status of brain white matter fiber tracts. Ki-67 and CD44/matrix metalloproteinase 9 are sensitive markers for reflecting the proliferation and infiltration of tumor cells. The present study analyzed pre-operative diffusion tensor images of 24 patients with pathologically confirmed World Health Organization glioma (I-IV). We observed lapse, infiltration and destruction of the peri-tumor corticospinal tract following reconstruction, and simultaneously detected the expression of Ki-67, CD44/matrix metalloproteinase 9 in samples. Expression of CD44 and matrix metalloproteinase 9 was not significantly correlated to the status of the peri-tumor corticospinal tract (r = 1.597, 4.859; P = 0.450, 0.088), while Ki-67 expression significantly correlated to its status (r = 6.590, P = 0.037). These findings demonstrate that highly proliferative gliomas result in damage to the peripheral corticospinal tract. | Chaoshi Niu Xiaorui Fei Changxin Wang Jiaming Mei Ying Liu Min Ding | 2010 | Neural Regeneration Research2010，5，17： | 0 |
| 7 | POE enhanced stabilities of CsPbX_(3)(X=Br,Ⅰ)perovskite and their white LED application显示文摘Perovskite has received extensive attention due to its excellent properties, just like photoelectric, while the instability has always troubled us to the wide application of perovskite materials. Herein, we proposed to use SiO_(2)and POE to encapsulate perovskite nanocrystals(PNCs). In this work, we have successfully prepared a series of perovskite composite materials and films with different concentration ratios.Due to the protection of POE, the luminous intensity of CsPbBr_(3)@POE composite film remained above 90% after stayed in the water for 42 days. The lead concentration of CsPbBr_(3)@POE composite film was 0.8 μg/m L after 48 h of immersing in deionized water. Namely, packaging PNCs in POE could effectively prevent Pb from overflowing reduce Pb pollution. Besides, the composite films showed a wide colour gamut with 117% of NTSC colour gamut, which shows that this composite material has a development prospect in the WLED field. | Enrou Mei Jiaming Li Qingyun He Yao Tong Ruowang Liu Hongbin Fan Xiaojuan Liang Weidong Xiang | 2022 | Journal of Energy Chemistry2022，31，4： | 0 |
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