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| 1 | Extrahepatic complications to cirrhosis and portal hypertension: Haemodynamic and homeostatic aspects显示文摘In addition to complications relating to the liver, patients with cirrhosis and portal hypertension develop extrahepatic functional disturbances of multiple organ systems. This can be considered a multiple organ failure that involves the heart, lungs, kidneys, the immune systems, and other organ systems. Progressive fibrosis of the liver and subsequent metabolic impairment leads to a systemic and splanchnic arteriolar vasodilatation. This affects both the haemodynamic and functional homeostasis of many organs and largely determines the course of the disease. With the progression of the disease, the circulation becomes hyperdynamic with cardiac, pulmonary as well as renal consequences for dysfunction and reduced survival. Infections and a changed cardiac function known as cirrhotic cardiomyopathy may be involved in further aggravation of other complications such as renal failure precipitatingthe hepatorenal syndrome.Patients with end-stage liver disease and related complications as for example the hepatopulmonary syndrome can only radically be treated by liver transplantation.As a bridge to this treatment,knowledge on the mechanisms of the pathophysiology of complications is essential for the choice of vasoactive drugs,antibiotics,drugs with specific effects on fibrogenesis and inflammation,and drugs that target specific receptors. | S?ren M?ller Jens H Henriksen Flemming Bendtsen | 2014 | World Journal of Gastroenterology2014，20，42： | 14 |
| 2 | Bonfils纤维气管镜用于难以预料的困难气管插管的研究(英文)显示文摘目的 难以预料和失败的困难气管插管是引起麻醉并发症和麻醉病死率的重要因素。本研究探讨Bon fils纤维气管镜用于处理难以预料的困难气管插管的价值。方法 2 1例行体外循环下冠状动脉搭桥术的患者 ,经一名高年资的麻醉医生使用普通咽喉镜两次插管失败后作为研究对象。测定Bonfils纤维气管镜插管的成功率和插管时间 ,同时测定判断困难气管插管的临床指标 :甲颏距离、Mal lampti分类、张口度、寰枕关节的活动度等。结果 除外一个患者第二次插管成功外 ,第一次插管的成功率是 95 %。平均插管时间 (5 0± 2 5 )秒。 | 严敏 Peter H Tonner Jens Scholz Berthold Bein | 2004 | 中华急诊医学杂志2004，13，3： | 8 |
| 3 | Liver cirrhosis and arterial hypertension显示文摘在有肝硬化的病人的典型调查结果是有低全面全身的脉管的抵抗的血管舒张,高动脉的依从,增加的心输出量,柜台规章的系统的第二等的激活(renin-angiotensin-aldosterone 系统,交感神经系统,加压素的版本) ,并且抵抗到 vasopressors。vasodilatory 状态通过 adrenomedullin 被调停, calcitonin 基因相关的肽,氮的氧化物,和另外的血管扩张药,并且最在内脏的区域被读。这组成一有效(尽管亲戚) 抵销到增加的动脉的血压。这评论在与肾的起源的本质性高血压和高动脉压的关系与肝硬化在病人在全身的血液动力学考虑改变。有高动脉压的题目(必要,第二等) 可以在肝硬化的发展期间变得正常血压,并且高动脉压很少与肝硬化在病人被表明,甚至在有 renovascular 疾病和高传播高血压蛋白原酶活动的情况中。至于在有明白高动脉压的肝脏硬化症的病人的 homoeostatic 规定的理解有许多争论。这很可能在平行包括血管舒张和血管缩小的联合。 | Jens H Henriksen Soren Moller | 2006 | World Journal of Gastroenterology2006，12，5： | 3 |
| 4 | 用传统方法与计算机辅助精液分析软件CRISMAS分析166名丹麦青年男性精液样本的结果比较显示文摘本研究以166名丹麦青年男性精液为样本,通过评估精于浓度和活力来比较传统精液分析与计算机辅助精液分析方法(CASA)(哥本哈根Rigshospitalet图像屋精子运动分析系统,CRISMAS软件4.6版本)。CRISMAS软件测定精子的浓度把精子活力分为三类。传统分析方法将精子活力分为四种状态。为了便于二者的比较,本文将传统的四种状态根据精子速度等级重新分为三个状态:rapidly progressive(A),slowly progressive(B)和non-progressive(C+D)。两种方法所研究的参数之间都有显著差异(P〈0.001)。与传统方法相比,CRISMAS高估了精子浓度以及快速运动精子的比例,因而低估了慢速运动和非运动精子。为分析研究结果是否会随精液分析时间而起伏变动,将精液分析结果按分析同期分为四个层次。结果表明CRISMAS对活力的分析结果比传统分析方法稳定,但两种方法都未表现出任何趋势。显然,无法比较CRISMAS CASA和传统分析方法在精子浓度和精子活力方面的分析结果。在临床上使用该软件时以及用其研究这些精子特性时需要说明这一点。 | Anne Vested Cecilia H Ramlau-Hansen Jens P Bonde Ane M Thulstrup Susanne L Kristensen Gunnar Toft | 2011 | Asian Journal of Andrology2011，13，3： | 3 |
| 5 | 当前围手术期处理模式:北欧五国结直肠外科医生调查显示文摘 | Kristoffer Lassen Pascal Hannemann Olle Ljungqvist Ken Fearon Cornelis H C Dejong Maarten F von Meyenfeldt Jonatan Hausel Jonas Nygren Jens Andersen Arthur Revhaug 王东 | 2005 | 英国医学杂志中文版2005，8，6： | 3 |
| 6 | Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source显示文摘BACKGROUND The trans-fat containing AMLN(amylin liver non-alcoholic steatohepatitis,NASH)diet has been extensively validated in C57BL/6J mice with or without the Lep^ob/Lep^ob(ob/ob)mutation in the leptin gene for reliably inducing metabolic and liver histopathological changes recapitulating hallmarks of NASH.Due to a recent ban on trans-fats as food additive,there is a marked need for developing a new diet capable of promoting a compatible level of disease in ob/ob and C57BL/6J mice.AIM To develop a biopsy-confirmed mouse model of NASH based on an obesogenic diet with trans-fat substituted by saturated fat.METHODS Male ob/ob mice were fed AMLN diet or a modified AMLN diet with trans-fat(Primex shortening)substituted by equivalent amounts of palm oil[Gubra amylin NASH,(GAN)diet]for 8,12 and 16 wk.C57BL/6J mice were fed the same diets for 28 wk.AMLN and GAN diets had similar caloric content(40%fat kcal),fructose(22%)and cholesterol(2%)level.RESULTS The GAN diet was more obesogenic compared to the AMLN diet and impaired glucose tolerance.Biopsy-confirmed steatosis,lobular inflammation,hepatocyte ballooning,fibrotic liver lesions and hepatic transcriptome changes were similar in ob/ob mice fed the GAN or AMLN diet.C57BL/6J mice developed a mild to moderate fibrotic NASH phenotype when fed the same diets.CONCLUSION Substitution of Primex with palm oil promotes a similar phenotype of biopsyconfirmed NASH in ob/ob and C57BL/6J mice,making GAN diet-induced obese mouse models suitable for characterizing novel NASH treatments. | Michelle L Boland Denise Oro Kirstine S T■lb■l Sebastian T Thrane Jens Christian Nielsen Taylor S Cohen David E Tabor Fiona Fernandes Andrey Tovchigrechko Sanne S Veidal Paul Warrener Bret R Sellman Jacob Jelsing Michael Feigh Niels Vrang James L Trevaskis Henrik H Hansen | 2019 | World Journal of Gastroenterology2019，25，33： | 3 |
| 7 | A misdiagnosed case of caesarean scar pregnancy显示文摘 | Jens Einenkel Patrick Stumpp Sabrina K?sling Lars-Christian Horn Michael H?ckel | 2005 | Archives of Gynecology and Obstetrics2005，，2： | 2 |
| 8 | Postoperative Neurocognitive Dysfunction in Elderly Patients after Xenon versus Propofol Anesthesia for Major Noncardiac Surgery: A Double-blinded Randomized Controlled Pilot Study显示文摘 | Jan H?cker Claudia Stapelfeldt J?rn Leiendecker Patrick Meybohm Robert Hanss Jens Scholz Berthold Bein | 2009 | Anesthesiology2009，，5： | 2 |
| 9 | Enucleation and Limited Pancreatic Resection Provide Long-Term Cure for Insulinoma in Multiple Endocrine Neoplasia Type 1显示文摘 | Bartsch Detlef K Albers Max Knoop Richard Kann Peter H Fendrich Volker Waldmann Jens | 2014 | Neuroendocrinology2014，，4： | 2 |
| 10 | Nutritional risk screening (NRS 2002): a new method based on an analysis of controlled clinical trials显示文摘 | JENS KONDRUP HENRIK H?JGAARD RASMUSSEN OLE HAMBERG ZENO STANGA | 2003 | Clinical Nutrition2003，，3： | 2 |
| 11 | Hydration simulation of C3S显示文摘 | JENNINGS H M JOHNSON | 1986 | Am Ceram Soc1986，69，5： | 1 |
| 12 | The influence of biologic factors on the surgical decision in advanced neuroblastoma显示文摘 | Hsu WM Jen YM Lee H | 2006 | Ann Surg Oncol2006，13，2： | 1 |
| 13 | A model for the microstructure of calcium silicate hydrate in cement paste 显示文摘 | JENNINGS H M | 2000 | Cem Coner Res2000，30，1： | 1 |
| 14 | Power modeling and low-power design of content addressable memories 显示文摘 | Hsiao H Y L Wang D H Jen C W | 2001 | Circuits and System2001，4，： | 1 |
| 15 | A caustic waterflooding process for heavy oils显示文摘 | Jennings H Y Jr | 1974 | J Petrol Technol1974，26，12： | 1 |
| 16 | Effects of drugs in subtoxic concentrations on the metabolic fluxes in human hepatoma cell line HepG2 显示文摘 | Jens N Fozia N Elmar H | 2009 | Toxicol Appl Pharm2009，240，： | 1 |
| 17 | Colloid model of C-S-H and implications to the problem of creep and shrinkage 显示文摘 | JENNINGS H M | 2004 | Mater Struct: Concr Sei Eng2004，37，1： | 1 |
| 18 | Symptomatic intraspinal oncocytic adrenocortical adenoma 显示文摘 | Jens S Florian H Ebner | 2009 | Endocr Pathol2009，20，1： | 1 |
| 19 | Simulation of Microstructure Development During the Hydration of a Cement Compound 显示文摘 | Jennings H M Johnson S K | 1986 | Journal of the American Ceramic Society1986，69，11： | 1 |
| 20 | Mechanisms of cement hydration 显示文摘 | BULLARD J W JENNINGS H M LIVINGSTON R A | 2011 | Cem Concr Res2011，41，12： | 1 |
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