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| 1 | ICC density predicts bacterial overgrowth in a rat model of post-infectious IBS显示文摘AIM:To investigate the interstitial cells of Cajal(ICC) number using a new rat model.METHODS:Sprague-Dawley rats were assigned to two groups.The first group received gavage with Campylobacter jejuni(C.jejuni) 81-176.The second group was gavaged with placebo.Three months after clearance of Campylobacter from the stool,precise segments of duodenum,jejunum,and ileum were ligated in self-contained loops of bowel that were preserved in anaerobic bags.Deep muscular plexus ICC(DMP-ICC) were quantified by two blinded readers assessing the tissue in a random,coded order.The number of ICC per villus was compared among controls,Campylobacter recovered rats without small intestinal bacterial overgrowth(SIBO),and Campylobacter recovered rats with SIBO.RESULTS:Three months after recovery,27% of rats gavaged with C.jejuni had SIBO.The rats with SIBO had a lower number of DMP-ICC than controls in the jejunum and ileum.Additionally there appeared to be a density threshold of 0.12 DMP-ICC/villus that was associated with SIBO.If ileal density of DMP-ICC was < 0.12 ICC/villus,54% of rats had SIBO compared to 9% among ileal sections with > 0.12(P<0.05).If the density of ICC was < 0.12 DMP-ICC/villus in more than one location of the bowel,88% of these had SIBO compared to 6% in those who did not(P<0.001).CONCLUSION:In this post-infectious rat model,the development of SIBO appears to be associated with a reduction in DMP-ICC.Further study of this rat model might help understand the pathophysiology of postinfectious irritable bowel syndrome. | Sam-Ryong Jee Walter Morales Kimberly Low Christopher Chang Amy Zhu Venkata Pokkunuri Soumya Chatterjee Edy Soffer Jeffrey L Conklin Mark Pimentel | 2010 | World Journal of Gastroenterology2010，16，29： | 3 |
| 2 | Validation study of the Ionospheric Forecast Model using the TOPEX total electron content measurements显示文摘 | Zhu L Schunk R W Jee G | 2006 | Radio Sciences2006，41，： | 1 |
| 3 | Estrogen and 'exercise'have a Synergistic Effect in Preventing Bone Loss in the Lumbar Vertebra and Femoral Neck of the Ovariectomized Rat显示文摘 | LI C Y JEE W S CHEN J L | 2003 | Calcif Tissue Int2003，72，1： | 1 |
| 4 | Magnesium sulphate attenuates tourniquet - induced hypertension and spinal e - los mRNA expression: a comparison with ketamine 显示文摘 | LEE D H JEE D L KIM S Y | 2007 | J Int Med Res2007，34，6： | 1 |
| 5 | The effects of aerobic exercise and T'ai Chi on blood pressure in older people:results of a randomized trial显示文摘 | Young D R Appel L J Jee S | 1999 | The Journal of the American Geriatric Society1999，47，3： | 1 |
| 6 | Studies on the analysis of Benzo (a) pyrene and its metabolites in biological samples by using high performance liquid chromatograpy/fluorescence detection and gas chromatography/mass spectrometry 显示文摘 | Won L Hye S S Jee E H | 2003 | Bull Korean Chem Soc2003，24，5： | 1 |
| 7 | Quantum Estimation of Impurity Effect for KDP Crystal Growth 显示文摘 | Asakuma Y Jee L Nishimura M | 2008 | Journal of Molecular Structure2008，851，： | 1 |
| 8 | Conversion of supraventricular arrhythmia tonormal rhythm by propofol and remifentanil: three cases report 显示文摘 | Choi E K Jee D L | 2014 | Korean J Anesthesiol2014，66，3： | 1 |
| 9 | Distributed and cooperative fuzzy controllers for traffic intersections group显示文摘 | Jee H L Lee K H | 1999 | IEEETransaction on System Man and Cybernetics1999，1999，29： | 1 |
| 10 | An interlaboratory trial to study the transfer ability of a spectral library for the identification of solvents using near-infrared spectroscopy显示文摘 | Yoon W L Jee R D Moffat A C | 2000 | Analyst2000，125，10： | 1 |
| 11 | Security analysis and improvements on WLANs 显示文摘 | WANG L SRINIVASAN B BHATTACHAP JEE N | 2011 | Journal of Networks2011，6，3： | 1 |
| 12 | A comparison of glucose concentration in paired specimens collected in serum separator and fluoride/potassium oxalate blood collection tubes under survey 'field' conditions 显示文摘 | Fernandez L Jee P Klein MJ | 2013 | Clin Biochem2013，6，45： | 1 |
| 13 | The effects of aerobic exercise and Tai-Chi on blood pressure in older people: results of a randomized trial显示文摘 | Young D R Appel L J Jee S | 1999 | J Am Geriatr Soc1999，47，： | 1 |
| 14 | A governor/turbine model for a twin-shaft combustion turbine 显示文摘 | Hannett L N Jee G Fardanesh B | 1995 | IEEE Transactions on Power Systems1995，10，1： | 1 |
| 15 | Comparison of texture development and superconducting properties of YBCO thin films prepared by TFA and PLD processes显示文摘 | JEE Y A LI M MA B MARONI V A FISHER B L BALACHANDRAN U | 2001 | Physica C2001，356，4： | 1 |
| 16 | Texture development and superconducting properties of YBa2Cu3Ox thin films prepared by a solution process in low oxygen partial pressure显示文摘 | JEE Y A MARONI M B LI V A FISHER M BALACHANDRA U B L | 2001 | Superconductor Science and Technology2001，14，： | 1 |
| 17 | Alaternin Glucoside Isomer From Cassia tora显示文摘 | Hee J L Jae S C Jee H J | 1998 | Phytochemistry1998，49，5： | 1 |
| 18 | Optical resolution of α-amino acids through enantioseleetive polymeric membranes based on polysaccharides显示文摘 | JANG H K JEE H K JON G L | 2003 | Journal of Membrane Science2003，213，： | 1 |
| 19 | Application of near-infrared spectroscopy to the determination of the sites of manufacture of proprietary products显示文摘 | Yoon W L Jee R D CharviμL A | 2004 | Journal of pH armaceutical and Biomedical Analysis2004，34，： | 1 |
| 20 | Diacylglycerylgal-actosides from Arisaema amurense 显示文摘 | Jee HJ Hongkun L Sam SK | 1996 | Phytochemistry1996，42，2： | 1 |
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