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| 1 | Mycoplasma infections and different human carcinomas显示文摘AIM To explore relationships between human carcinomas and mycoplasma infection.METHODS Monoclonal antibody PD4, which specifically recognizes a distinct protein from mycoplasma hyorhinis, was used to detect mycoplasma infection in different paraffinembedded carcinoma tissues with immunohistochemistry. PCR was applied to amplify the mycoplasma DNA from the positive samples for confirming immunohistochemistry.RESULTS Fifty of 90 cases (56%) of gastric carcinoma were positive for mycoplasma hyorhinis. In other gastric diseases, the mycoplasma infection ratio was 28% (18/49) in chronic superficial gastritis, 30% (14/ 46) in gastric ulcer and 37% (18/ 49) in intestinal metaplasia. The difference is significant with gastric cancer (X2=12.06, P<0.05). In colon carcinoma, the mycoplasma infection ratio was 55.1% (32/58), but it was 20.9% (10/49) in adenomarous polyp (X2=13.46, P<0.005).Gastric and colon cancers with high differentiation had a higher mycoplasma infection ratio than those with low differentiation (P< 0.05). Mycoplasma infection in esophageal cancer, lung cancer, breast cancer and glioma was 50.9% (27/53), 52.6% (31/ 59), 39.7%(25/63) and 41% (38/91), respectively. The mycoplasma DNA was successfully amplified with the DNA extracted from the cancer tissues that were positive for mycoplasma infection (detected with antibody PD4).CONCLUSION There was high correlation between mycoplasma infection and different cancers, which suggests the possibility of an association between the two. The mechanism involved in oncogenesis by mycoplasma remains unknown. | Su Huang Ji You Li Jan Wu Lin Meng Cheng Chao Shou Beijing Institute for Cancer Research, Peking University School of Oncology, Beijing 100034. ChinaSu Huang, received B. A from Jiangxi Medical College of China in 1994. Now she is a graduate student pursuing a Ph. D degree at the Peking University School of Oncology. | 2001 | World Journal of Gastroenterology2001，7，2： | 18 |
| 2 | Effects of sodium bicarbonate, disodium carbonate, and a sodium bicarbonate/carbonate mixture on the PCO2 of blood in a closed system显示文摘 | Joseph IS Nancy E Jan L | 1995 | J Lab & Clin Med1995，126，： | 2 |
| 3 | Coeliac artery stenusis and antiphospholipid(Hughes)syndrome/antiphospholipid antibodies显示文摘 | Sangle SR Jan W Lau IS | 2006 | Clin Exp Rheunatol2006，24，3： | 1 |
| 4 | Cytological Diagnosis of Penicillium marneffei Infection显示文摘 | Jan IS Chung PF Wang JY | 2008 | J Formos Med Assoc2008，107，6： | 1 |
| 5 | Cytological diagnosis of Penicillium marneffei infection 显示文摘 | Jan IS Chung PF Wang JY | 2008 | J Formos Med Assoc2008，107，： | 1 |
| 6 | Fluoroquinolone resistance in Mycobacterium tuberculosis isolates: associated genetic mutations and relationship to antimierobial exposure显示文摘 | Wang JY Lee LN Lai HC Wang SH Jan IS YU CJ Hsueh PR Yang PC | 2007 | J Antimierob Chemother2007，59，： | 1 |
| 7 | Utility of thyroid transcription factor-1 expression in the differential diagnosis of metastatic adenocarcinoma of serous effusion specimens prepared using the cell transfer technique显示文摘 | Jan IS Chung PF Weng MH | 2006 | J Formos Med Assoc2006，105，9： | 1 |
| 8 | Pancreaticojejunal anastomosis leak after multivariable analysis of pe- rioperative risk factors显示文摘 | Yeh 'IS Jan YY Jen LB | 1977 | J Surg Res1977，67，2： | 1 |
| 9 | Video-assisted endoscopies thyroidectomy显示文摘 | Yeh IS Jan YY Hsu BIL | 2000 | Am J Surg2000，180，2： | 1 |
| 10 | Empirical treatment with a fluoroquinolone delays the treatment for tuberculosis and is associated with a poor prognosis in endemic areas显示文摘 | Wang JY Hsueh PR Jan IS Lee LN Liaw YS Yang PC Luh KT | 2006 | Thorax2006，61，10： | 1 |
| 11 | Coeliac artery stenusis and an-tiphospholipid (Hughes) s yndrome/antiphospholipid antibodies 显示文摘 | Sangle SR Jan W Lau IS | 2006 | Clin Exp Rheunatol2006，24，3： | 1 |
| 12 | Video - assisted endoscopicthyroidectomy 显示文摘 | Yeh IS Jan YY Hsu BR | 2000 | Am J Surg2000，180，2： | 1 |
| 13 | Wound hea ling: an o- verview 显示文摘 | Bronghton G Jan is JE A ttinger CE | 2006 | Plast Reconstr Surg2006，，： | 1 |
| 14 | Serial analysis of fat-containing macrophages in bronchoalveolar lavage fluid in a patient with fat embolism syndrome显示文摘 | Wang JY Kuo PH Jan IS Lee LN Yang PC | 2001 | J Formos Med Assoc2001，100，8： | 1 |
| 15 | Empirival treatment with a fluoroquinolone delays the treatment for tuberculosis and is associ- ated with a poor prognosis in endemic areas 显示文摘 | Wang JY Hsueh PR Jan IS | 2006 | Thorax2006，61，： | 1 |
| 16 | Utility of thyroid transcription factor-1 expression in the differential diagnosis of metastatic adenocarcinoma of serous effusion specimens prepared using the cell transfer technique显示文摘 | Jan IS Chung PF Weng MH | | 0，，09： | 1 |
| 17 | Coeliac artery stenusisand an tiphospholipid (Hughes) syndrome/antiphospholipid antibodies 显示文摘 | Sangle SR Jan W Lau IS etal | 2006 | Clin Exp Rheunatol2006，24，3： | 1 |
| 18 | Effects of sodium bicarbonate,disodium Bicarbonate,disodium carbonate,and a sodium bicarclosed system显示文摘 | Joseph IS Nancy E Jan L | 1995 | Jlab & Clin Med1995，126，： | 1 |
| 19 | Cytological diagnosis of Penicillium rnarneffei infection 显示文摘 | Jan IS Chung PF Wang JY | 2008 | J Forrnos Med Assoc2008，107，6： | 1 |
| 20 | Evaluation of the Bruker Bioty- per matrix-assisted laser desorption ionization-time of flight mass spec- trometry system for identification of blood isolates of Vibrio species 显示文摘 | Cheng WC Jan IS Chen JM | 2015 | J Clin Microbiol2015，53，5： | 1 |
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