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| 1 | 进展期胃癌的外科治疗显示文摘全球每年约有800000例胃癌新发病例,居于最常见的恶性肿瘤第4位,肿瘤相关死亡原因第2位。虽然胃癌发病率在西方国家持续下降,但是在亚洲、拉丁美洲和东欧依旧保持较高水平。据报道,全球大约42%的胃癌患者在中国。随着手术技术的改进、综合治疗方法的进步以及早期诊断能力的提高,最近几十年胃癌的总体生存率得到逐步提升。 | Kyung Min Kim 胡彦锋 Ji Yeong An Hyoung LI Kim Jae Ho Cheong Woo Jin Hyung Sung Hoon Noh | 2011 | 中华消化外科杂志2011,10,6: | 18 |
| 2 | Synergistic and feedback signaling mechanisms in the regulation of inflammation in respiratory infections显示文摘肺病,最典型、经常的更低的呼吸的道感染(LRTI ) ,是在美国的健康问题的一个领先的原因。细菌在孩子和成年人代表肺病的大多数占优势的原因。尽管有单个细菌的感染的肺病是普通的,有肺病的病人的重要部分是 polymicrobial。这感染经常是有象 cytokines 那样的另外的生理的因素和生长因素的 complexed。Nontypeable Haemophilus influenzae (NTHi ) 是在呼吸系统的最经常恢复的克否定的细菌的病原体并且导致强壮的煽动性的回答。NTHi 另外有另外的呼吸病原体的 synergizes 例如链球菌 pneumoniae 和呼吸病毒和支持 inflammatory cytokines,例如肿瘤坏死 factor-alpha (TNF-α) 。它是引人注目的那 NTHi 不仅有象转变生长因素贝它那样的生长因素的 synergizes (TGF-β) ,而且利用象 TGF-β 那样的生长因素受体;受体和表皮的生长因素受体(EGFR ) ,提高煽动性的回答。尽管适当发炎是对入侵病原体的保护的回答,不受管束的煽动性的回答对主人经常有害。因此,发炎必须紧被调整。人的免疫系统为控制 overactive 发展了策略煽动性的反应。一如此的重要机制经由为发炎的否定反馈管理者的规定。CYLD,多功能的 deubiquitinase,是原来作为肿瘤 suppressor 报导了,但是最近为原子 factor-kappa B 作为一个否定管理者被识别(NF-κ B ) 发信号。它被 NTHi 和 TNF-α 导致;经由 NF-κ B 依赖的机制,从而为紧在 NTHi 感染控制发炎用作一个可诱导的否定反馈管理者。 | Wenzhuo Y Wang Jae Hyang Lim Jian-Dong Li | 2012 | Cellular & Molecular Immunology2012,9,2: | 10 |
| 3 | Approaching 18%efficiency of ternary organic photovoltaics with wide bandgap polymer donor and well compatible Y6:Y6-1O as acceptor显示文摘A series of ternary organic photovoltaics(OPVs)are fabricated with one wide bandgap polymer D18-Cl as donor,and well compatible Y6 and Y6-1O as acceptor.The open-circuit-voltage(V_(OC))of ternary OPVs is monotonously increased along with the incorporation of Y6-1O,indicating that the alloy state should be formed between Y6 and Y6-1O due to their excellent compatibility.The energy loss can be minimized by incorporating Y6-1 O,leading to the V_(OC)improvement of ternary OPVs.By finely adjusting the Y6-1O content,a power conversion efficiency of 17.91%is achieved in the optimal ternary OPVs with 30 wt%Y6-1O in acceptors,resulting from synchronously improved short-circuit-current density(JSC)of 25.87 mA cm^(-2),fill factor(FF)of 76.92%and V_(OC)of 0.900 V in comparison with those of D18-Cl:Y6 binary OPVs.The JSC and FF improvement of ternary OPVs should be ascribed to comprehensively optimal photon harvesting,exciton dissociation and charge transport in ternary active layers.The more efficient charge separation and transport process in ternary active layers can be confirmed by the magnetophotocurrent and impedance spectroscopy experimental results,respectively.This work provides new insight into constructing highly efficient ternary OPVs with well compatible Y6 and its derivative as acceptor. | Xiaoling Ma Anping Zeng Jinhua Gao Zhenghao Hu Chunyu Xu Jae Hoon Son Sang Young Jeong Caixia Zhang Mengyang Li Kai Wang He Yan Zaifei Ma Yongsheng Wang Han Young Woo Fujun Zhang | 2021 | National Science Review2021,8,8: | 3 |
| 4 | Role of extracellular vesicles in lung diseases显示文摘Extracellular vesicles(EVs)are anuclear particles composed of lipid bilayers that contain nucleic acids,proteins,lipids,and organelles.EVs act as an important mediator of cell-to-cell communication by transmitting biological signals or components,including lipids,proteins,messenger RNAs,DNA,microRNAs,organelles,etc,to nearby or distant target cells to activate and regulate the function and phenotype of target cells.Under physiological conditions,EVs play an essential role in maintaining the homeostasis of the pulmonary milieu but they can also be involved in promoting the pathogenesis and progression of various respiratory diseases including chronic obstructive pulmonary disease,asthma,acute lung injury/acute respiratory distress syndrome,idiopathic pulmonary fibrosis(IPF),and pulmonary artery hypertension.In addition,in multiple preclinical studies,EVs derived from mesenchymal stem cells(EVs)have shown promising therapeutic effects on reducing and repairing lung injuries.Furthermore,in recent years,researchers have explored different methods for modifying EVs or enhancing EVs-mediated drug delivery to produce more targeted and beneficial effects.This article will review the characteristics and biogenesis of EVs and their role in lung homeostasis and various acute and chronic lung diseases and the potential therapeutic application of EVs in the field of clinical medicine. | Li Zhou Hong Luo Jae Woo Lee | 2022 | Chinese Medical Journal2022,,15: | 2 |
| 5 | Enhanced plasticity of twin-roll cast ZK60 magnesium alloy through differential speed rolling显示文摘 | Xibing Gong Suk Bong Kang Saiyi Li Jae Hyung Cho | 2009 | Materials and Design2009,,9: | 2 |
| 6 | Transduction of human catalase mediated by an HIV-1 tat protein basic domain and arginine-rich peptides into mammalian cells 显示文摘 | LI H J JAE H B WON S E | 2001 | Free Radical Biology & Medicine2001,31,11: | 1 |
| 7 | Microstructural evolution and mechanical properties of binary Mg-xBi(x=2,5,and 8 wt%)alloys显示文摘The microstructures and mechanical properties of Mg-x Bi(x=2,5,and 8 wt%)were investigated compared with pure Mg.The ascast Mg-Bi billets consist of dendriticα-Mg grain matrix,divorced eutectic Mg_(3)Bi_(2) phase and secondary precipitated Mg_(3)Bi_(2) phase.After homogenization,secondary precipitated Mg_(3)Bi_(2) particles were all dissolved into the matrix,while most of the divorced eutectic Mg_(3)Bi_(2) intermetallic compounds retained.All the as-extruded samples exhibit fully dynamic recrystallization(DRX)and the average grain size decreases and the amount of nano-scale Mg_(3)Bi_(2) precipitates increases with increasing Bi content.Additionally,Bi alloying has little influence on the texture of the as-extruded pure Mg,with all the samples showing typical basal texture.As the results of grain refinement and precipitation hardening,the strengths of the as-extruded samples increase under both tensile and compressive tests.Besides,the yield asymmetry significantly decreases with Bi content.Moreover,all the as-extruded samples represent similar ductility under compression,while the tensile elongation first increases and then decreases with more Bi added.The as-extruded Mg-5Bi alloy demonstrates good combination of strength and ductility.However,Mg-8Bi alloy displays lower tensile ductility than that of Mg-5Bi alloy due to the presence of abundant undissolved coarse Mg_(3)Bi_(2) particles,which act as cracking sources during tensile test.Furthermore,the strain hardening rate,strain hardening exponent n,and hardening capacity Hc are greatly reduced by Bi addition,mainly owing to the enhanced synergy effects of grain refinement and numerous Mg_(3)Bi_(2) precipitates. | Hui Yu Shaoda Fan Shuaiju Meng Jae Ok Choi Zhongjie Li Yohan Go Young Min Kim Weimin Zhao Bong Sun You Kwang Seon Shin | 2021 | Journal of Magnesium and Alloys2021,9,3: | 1 |
| 8 | Laser clad Ni-base alloy added nano- and micron-size CeO2 composites显示文摘 | Zhang S H Li M X Tong Yul Cho Jae Hong Yoon Chan Gyu Lee and He Y Z | 2008 | Optics & Laser Technology2008,40,5: | 1 |
| 9 | Effect of the addition of Sm2 03 on the microstructure of laser cladding alloy coating layers显示文摘 | Zhang Shihong Li Mingxi Jae Hong Yoon | 2008 | Metals and Materials International2008,14,3: | 1 |
| 10 | Dayanand agasarproduction,characterization and application of kera-tinase from Streptomyces gulbargensis显示文摘 | Dastager G S Jae C L Li W J | 2009 | Biore-source Technology2009,100,: | 1 |
| 11 | Synthesis and Characterization of Photosensitive Poly(imide sulfonates) for Fuel Cell Application显示文摘The novel sulfonated polyimide membranes were successfully synthesized by thermal imidization with monomers of 4,4'-(hexafluoroisopropylidene)diphthalic anhydride (6FDA), 4,4'-diamino-diphenyl ether-2,2'-disulfonic acid (SODA) and 3,3'-diaminochalcone (3DAC). Photosensitive chalcone moiety was introduced to the main chain of copolymers, and the photocrosslinking of resulting copolymer in aqueous electrolyte was attempted. A series of sulfonated copolyimide precursors containing chalcone functional groups in the main chain were prepared with different sulfonation degrees by controlling the molar ratio of SODA, 6FDA and 3DAC. The polymer membranes were prepared from these sulfonated aromatic precursors by solution casting and subsequent thermal imidization. The crosslinking with UV irradiation was attempted in the presence or absence of distilled water. The characterizations of the resulting membrane such as the ion-exchange capacity, water absorption and ionic conductivity were performed with respect to the copolymer compositions and the photocrosslinking conditions. | 文璞山 LIU Hui KIM Jae Hoon LI Xiangdan LEE Myong-Hoon | 2013 | Journal of Wuhan University of Technology(Materials Science)2013,28,4: | 1 |
| 12 | Establishment of Caenorhabditis elegans SID-1-Dependent DNA Delivery System in Cultured Silkworm Cells显示文摘 | Jian Xu Kaito Yoshimura Hiroaki Mon Zhiqing Li Li Zhu Kazuhiro Iiyama Takahiro Kusakabe Jae Man Lee | 2014 | Molecular Biotechnology2014,,3: | 1 |
| 13 | Soaking RNAi-mediated modification of Sf9 cells for baculovirus expression system by ectopic expression of Caenorhabditis elegans SID-1显示文摘 | Jian Xu Yudai Nagata Hiroaki Mon Zhiqing Li Li Zhu Kazuhiro Iiyama Takahiro Kusakabe Jae Man Lee | 2013 | Applied Microbiology and Biotechnology2013,,13: | 1 |
| 14 | Transduction of human catalase mediated by an HIV-1 tat protein basic domain and argininerich peptides into mammalian cells显示文摘 | Li H J Jae H B Won S E | 2001 | Free Radical Biol Med2001,31,11: | 1 |
| 15 | Characterization on the coatings of Ni-base alloy with nano-and micron-size Sm2O3addition prepared by laser deposition显示文摘 | ZHANGShihong LI mingxi YOON Jae Hong CHU Tong Yul | 2008 | Materials Chemistry and Physics2008,112,: | 1 |
| 16 | Relative Performance Evaluation and Related Peer Groups in Executive Compensation Contracts显示文摘 | Gong Guojin Laura Yue Li Jae Yong Shin | | 0,,03: | 1 |
| 17 | Transduction of human catalase mediated by an HIV-1 tat protein basic domain and arginine-rich peptides into mammalian cells显示文摘 | LI H J JAE H B WON S E | 2001 | Free Radical Biology & Medicine2001,31,11: | 1 |
| 18 | Transduction of human catalase mediated by an HIV - 1 tat protein basic domain and arginine - rich peptides into mammalian cells 显示文摘 | Li H J Jae H B Won S E | 2001 | Free Radical Biology & Medicine2001,31,11: | 1 |
| 19 | Eletronic band structure and photocatalytic activity of Ln2Ti2O7(Ln=La, Pr, Nd) 显示文摘 | Dong Won Hwang Jae Sung Lee Wei Li | 2003 | J Phy Chem B2003,107,21: | 1 |
| 20 | Percutaneous core needle biopsy for small (≤10mm) lung nodules: accurate diagnosis and complication rates显示文摘 | Jae LI June IH Miyeon Y | 2012 | Diagn Interv Radiol2012,18,6: | 1 |