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274篇 您的检索式:作者名="Jacobson F"
    题名 作者 年代 出处 被引量
1Regression of cirrhosis during treatment with tenofovir disoproxil fumarate for chronic hepatitis B: a 5-year open-label follow-up study显示文摘Patrick Marcellin Edward Gane Maria Buti Nezam Afdhal William Sievert Ira M Jacobson Mary Kay Washington George Germanidis John F Flaherty Raul Aguilar Schall Jeffrey D Bornstein Kathryn M Kitrinos G Mani Subramanian John G McHutchison E Jenny Heathcote 2012The Lancet2012,,:14
2Consecutive fecal calprotectin measurements for predicting relapse in pediatric Crohn's disease patients显示文摘BACKGROUND Asymptomatic children with Crohn's disease(CD) require ongoing monitoring to ensure early recognition of a disease exacerbation.AIM In a cohort of pediatric CD patients, we aimed to assess the utility of serial fecal calprotectin measurements to detect intestinal inflammatory activity and predict disease relapse.METHODS In this prospective longitudinal cohort study, children with CD on infliximab therapy in clinical remission were included. Fecal calprotectin levels were assessed at baseline and at subsequent 2-5 visits. Clinical and biochemical disease activity were assessed using the Pediatric Crohn's Disease Activity Index, Creactive protein and erythrocyte sedimentation rate at baseline and at visits over the following 18 mo.RESULTS 53 children were included and eighteen patients(34%) had a clinical disease relapse during the study. Baseline fecal calprotectin levels were higher in patients that developed symptomatic relapse [median(interquartile range), relapse 723μg/g(283-1758) vs 244 μg/g(61-627), P = 0.02]. Fecal calprotectin levels > 250μg/g demonstrated good predictive accuracy of a clinical flare within 3 mo(area under the receiver operator curve was 0.86, 95% confidence limits 0.781 to 0.937).CONCLUSION Routine fecal calprotectin testing in children with CD in clinical remission is useful to predict relapse. Levels > 250 μg/g are a good predictor of relapse in the following 3 mo. This information is important to guide monitoring standards used in this population.Alice Jane Foster Matthew Smyth Alam Lakhani Benjamin Jung Rollin F Brant Kevan Jacobson 2019World Journal of Gastroenterology2019,25,10:3
3Adenosine-induced cell death : evidence for receptor-mediated signalling显示文摘Jacobson KA Hoffmann C Cattabeni F 1999Apoptosis1999,4,:1
4The influence of toothbrushing frequency and post-brushing rising on caries experience in a caries clinical trial显示文摘Chestnut IG Schafer F Jacobson APM 1998Community Dent Oral Epidemiol1998,26,6:1
5Employee perceptions of diabetes education needs: a focus group study显示文摘Wood F Jacobson S 2005AAOHN J2005,53,10:1
6Standard imaging in silicosis and coal worker's pneumoconiosis 显示文摘Stark P Jacobson F Shaffer K 1992Radiologic Clinics of North America1992,30,6:1
7Yields of cultured Pacific oysters Crassostrea gigas Thunberg improved after one generation of selection 显示文摘Langdon C Evans F Jacobson D 2003Aquaculture2003,220,:1
8Purine and pyrimidine (P2) receptors as drug targets显示文摘Jacobson K A Jarvis M F Williams M 2002J Med Chem2002,45,:1
9Joint genetic susceptibility to type 1 diabetes and autoimmune thyroiditis : from epidemiology to mechanisms显示文摘Huber A Menconi F Corathers S Jacobson EM Tomer Y 2008Endocr Rev2008,29,6:1
10The estrogen receptor locus is associated with a major gene influencing htter size in pigs 显示文摘ROTHSCHILD M F JACOBSON C VASKE D 1996Proc Natl Acad Sci USA1996,93,1:1
11On the nature of tribiological contact in automotive brakes显示文摘ERIKSSON M BERGMAN F JACOBSON S 2002Wear2002,252,12:1
12Regression of cirrhosis during treatment with tenofovir disoproxil fumarate for chronic hepatitis B: a 5-year open-label follow-up study显示文摘Patrick Marcellin Edward Gane Maria Buti Nezam Afdhal William Sievert Ira M Jacobson Mary Kay Washington George Germanidis John F Flaherty Raul Aguilar Schall Jeffrey D Bornstein Kathryn M Kitrinos G Mani Subramanian John G McHutchison E Jenny Heathcote 2012The Lancet2012,,:1
13Oxidation of alcohols by molybdenum and tungsten peroxo complexes 显示文摘Jacobson S E Muccigrosso D A Mares F 1979Journal of Organic Chemistry1979,44,:1
14Mechanisms compen-sating for visual field restriction in adolescents with damage to theretro-geniculate visual system显示文摘Jacobson Ll Lennartsson F Pansell T 2012Eye(Lond)2012,26,11:1
15Employee perceptions of diabetes education needs:a focus group study显示文摘Wood F Jacobson S 2005AAOHNJ2005,53,10:1
16Standard imaging in silicosis and coal worker' s pneumoconiosis 显示文摘STARK P JACOBSON F SHAFFER K 1992Radiol Clin North Am1992,30,6:1
17Subduction and exhumation of the Pelona-Orocopia-Rand shists, southern California显示文摘Jacobson C E Oyarzabal F R Haxel G B 1996Geology1996,24,:1
18Baseline subtraction using robust local regression estimation 显示文摘Ruckstuhl A F Jacobson M P Field R W 2001Journal of Quantitative Spectroscopy and Radiative Transfer2001,68,2:1
19Influence of Disc Topography on Generation of Brake Squeal显示文摘Bergman F Eriksson M Jacobson S 1999Wear1999,225,1:1
20Yields of cultured Pacific oysters Crassostrea gigas Thunberg improved after one generation of selection显示文摘Langdon C J Evans F Jacobson D 2003Aquaculture2003,220,:1
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