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| 1 | Sensory innervation around immediately vs. delayed loaded implants: a pilot study显示文摘Although neurophysiological and psychophysical proof of osseoperception is accumulating, histomorphometric evidence for the neural mechanisms of functional compensation following immediate and delayed implant loading is still lacking. For this randomized split-mouth study, six mongrel dogs randomly received one of four treatment protocols at 36 implant-recipient sites over 16 weeks(third maxillary incisor, third and fourth mandibular premolar): immediate implant placement and immediate loading(IIP1IL);delayed implant placement and delayed loading(DIP1DL); delayed implant placement and immediate loading(DIP1IL); and natural extraction socket healing(control). Histomorphometry was performed in the peri-implant bone and soft tissues within 300 mm around the implants. Immunocytochemistry and transmission electron microscopy were used to confirm the presence of neural structures and to reveal their ultrastructural characteristics, respectively. Myelinated nerve fibres densely populated the peri-implant crestal gingival and apical regions, although they were also identified in the woven bone and in the osteons near the implant threads. Compared with the control group in the mandible, the group that received IIP1 IL showed a higher innervation(in Nmm22, 5.9461.12 vs. 3.1560.63,P,0.001) and smaller fibre diameter(in mm, 1.3760.05 vs. 1.6460.13, P50.016), smaller axon diameter(in mm, 0.8960.05 vs.1.2460.10, P50.009) and g-ratio(0.6460.04 vs. 0.7660.05, P,0.001) in the middle region around the implants. Compared with DIP1 IL in the mandible, IIP1 IL had a higher nerve density(in Nmm22, 13.2362.54 vs. 9.6461.86, P50.027), greater fibre diameter(in mm, 1.3260.02 vs. 1.2060.04, P50.021), greater axon diameter(in mm, 0.9260.01 vs. 0.8960.03, P50.035) and lower g-ratio(0.6960.01 vs. 0.7460.01, P50.033) in the apical region around the implants. It may be assumed that the treatment protocol with IIP1 IL is the preferred method to allow optimized peri-implant re-innervation, but further functional measurements are still required. | Yan Huang Jeroen van Dessel Wendy Martens Ivo Lambrichts Wei-Jian Zhong Guo-Wu Ma Dan Lin Xin Liang Reinhilde Jacobs | 2015 | International Journal of Oral Science2015，7，1： | 7 |
| 2 | 择期髋膝关节置换患者静脉血栓栓塞性疾病预防的AAOS指南显示文摘本临床实践指南是对2007年已发表的一个类似指南进行撤换。我们根据现有的文献,对患者的筛选,危险因素的评估,静脉血栓疾病(VTED)的预防性治疗,鼓励患者术后活动以及使用椎管内麻醉和下腔静脉过滤器等各方面进行了评估。我们建议对有静脉血栓栓塞性疾病病史但没有其他潜在危险因素的患者需要进行进一步的评估,患者应评估是否患有某些已知的出血性疾病以及是否存在活动性的肝脏疾病。没有VTED或出血高风险的患者也应接受药物及机械压缩装置来预防VTED的发生,但我们并没有推荐具体的药物和/或机械装置。我们建议,行择期髋膝关节置换术的患者术后应进行早期活动。采用椎管内麻醉有助于减少失血,但没有发现椎管内麻醉会影响VTED发生的证据。目前也没有明确的证据表明对有药物预防禁忌和/或已知VTED的患者使用下腔静脉过滤器能防止肺栓塞的发生。 | Mont MA Jacobs JJ 余霄 俞光荣 | 2012 | 中华关节外科杂志(电子版)2012，6，4： | 6 |
| 3 | Quetiapine as an adjunc- tive pharmacotherapy for the treatment of non - remitting generalized anxiety disorder:A flexible -dose,open -label polit trial显示文摘 | Katzman MA Vermani M Jacobs L | 2008 | JAnx- iety Disord2008，22，： | 1 |
| 4 | Patterns of enhancementon breast MR images :interpretation and imag- ing pitfalls 显示文摘 | Macura KJ Ouwerkerk R Jacobs MA | 2006 | Radiographics2006，26，6： | 1 |
| 5 | A prospective study compa- ring video capsule endoscopy with double-balloon enteruscopy in pa- tients with obscure gastrointestinal bleeding 显示文摘 | Hadithi M Heine GD Jacobs MA | 2006 | Am J Gastroenterol2006，101，1： | 1 |
| 6 | Cotinine in the serum,sali-va,and urine of nonsmokers,passive smokers,and active smokers显示文摘 | Wall MA Johnson J Jacob P | 1988 | Am J Public Health1988，78，6： | 1 |
| 7 | Proton magnetic resonance spectroscopic imaging of human breast cancer:a preliminary study显示文摘 | Jacob MA Barker PB Bottomley PA | 2004 | J Magn Reson Imaging2004，19，1： | 1 |
| 8 | Characterization of musculoskeletal lesions on 3-T proton MR spectroscopy 显示文摘 | Fayad LM Barker PB Jacobs MA | 2007 | Am J Roentgenol2007，188，6： | 1 |
| 9 | Guidelines for the psychosocial evaluation of living unrelated kidney donors in the United States显示文摘 | Dew MA Jacobs CL Jowsey SG | 2007 | Am J Transplant2007，7，： | 1 |
| 10 | Cognitive behavioral therapy for adolesccnt depression:meta analytic investigation of changes in effect size estimates显示文摘 | Klein JB Jacobs RH Reinecke MA | 2007 | J Am Acad Child Adolesc Psychiatry2007，46，11： | 1 |
| 11 | ACC/AHA guidelines for the martagement of patients with ST-elevation myocardial infarction-executive summary:port of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1999 Guidelines for the Management of patients with Acute Myocardial Infarction) 显示文摘 | Antman EM Anbe DT Armstrong PW Bates ER Green LA Hand M Hochman JS Krumholz HM Kushner FG Lamas GA Mullany CJ Ornato JP pearle DL Sloan MA Smith SCJr Alpert JS Anderson JL Faxon DP Fuster V Gibbons RJ Gregoratos G Halperin JL Hiratzka LF Hunt SA Jacobs AK American College of Cardiology American Heart Association Task Force on Practice Guidelines | 2004 | Circulation2004，110，5： | 1 |
| 12 | Daily target localization for prostate patients based on 3D image correlation显示文摘 | Paskalev K Ma M Jacob R | 2004 | Phys Med Biol2004，49，6： | 1 |
| 13 | The role of parallel diffusion- weighted imaging and apparent diffusion coefficient (ADC) map values for evaluating breast lesions: preliminary results 显示文摘 | Jin G An N Jacobs MA | 2010 | Acad Radiol2010，17，： | 1 |
| 14 | Variation in newborn size according to pregnancy weight change by trimes- ter 显示文摘 | Brown JE Murtangh MA Jacobs DR Jr | 2002 | Am J Clin Nutr2002，76，1： | 1 |
| 15 | Activity assessment of Tunisian olive leaf extracts against the trophozoite stage of Acanthamoeba显示文摘 | Ines Sifaoui Atteneri López-Arencibia Carmen Ma Martín-Navarro Nadia Chammem Mondher Mejri Jacob Lorenzo-Morales Manef Abderabba José E. Pi?ero | 2013 | Parasitology Research2013，，8： | 1 |
| 16 | Uterine fibroids:diffusion-weighted Mr imaging for monitoring therapywith focused ultrasound surgery- preliminary study显示文摘 | Jacobs MA Herskovits EH Kim HS | 2005 | Radiology2005，236，1： | 1 |
| 17 | Characterization of the human pancreatic islet proteome by two-dimensional LC/MS/MS 显示文摘 | Metz TO Jacobs JM Gritsenko MA | 2006 | J Proteome Res2006，5，12： | 1 |
| 18 | Context-sensitive half-time in multicompartment pharmacokinetic models for intravenous anesthetic drugs显示文摘 | Hughes MA Glass PS Jacobs JR | | 0，，3： | 1 |
| 19 | A prospective study compa- ring video capsule endoscopy with double-balloon enteroscopy in patients with obscure gastrointestinal bleeding 显示文摘 | Hadithi M Heine GD Jacobs MA | 2006 | Am J Gastroenterol2006，101，1： | 1 |
| 20 | Intertrochanteric osteotomy for avascular necrosis of the femoral head显示文摘 | Jacobs MA Hungerford DS Krachow KA | 1989 | J Bone Joint Surg (Am)1989，71，： | 1 |
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