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87篇 您的检索式:作者名="Jacobi F"
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1Reproducibility of thrombus volume quantification in multicenter computed tomography pulmonary angiography studies显示文摘AIM To evaluate reproducibility of pulmonary embolism(PE) clot volume quantification using computed tomography pulmonary angiogram(CTPA) in a multicenter setting.METHODS This study was performed using anonymized data in conformance with HIPAA and IRB Regulations(March 2015-November 2016). Anonymized CTPA data was acquired from 23 scanners from 18 imaging centers using each site's standard PE protocol. Two independent analysts measured PE volumes using a semi-automated region-growing algorithm on an FDA-approved image analysis platform. Total thrombus volume(TTV) was calculated per patient as the primary endpoint. Secondary endpoints were individual thrombus volume(ITV), Qanadli score and modified Qanadli score per patient. Inter-and intra-observer reproducibility were assessed using intra-class correlation coefficient(ICC) and BlandAltman analysis. RESULTS Analyst 1 found 72 emboli in the 23 patients with a mean number of emboli of 3.13 per patient with a range of 0-11 emboli per patient. The clot volumes ranged from 0.0041-47.34 cm3(mean +/-SD, 5.93 +/-10.15 cm3). On the second read, analyst 1 found the same number and distribution of emboli with a range of volumes for read 2 from 0.0041 – 45.52 cm3(mean +/-SD, 5.42 +/-9.53 cm3). Analyst 2 found 73 emboli in the 23 patients with a mean number of emboli of 3.17 per patient with a range of 0-11 emboli per patient. The clot volumes ranged from 0.00459-46.29 cm3(mean +/-SD, 5.91 +/-10.06 cm3). Inter-and intraobserver variability measurements indicated excellent reproducibility of the semi-automated method for quantifying PE volume burden. ICC for all endpoints was greater than 0.95 for inter-and intra-observer analysis. Bland-Altman analysis indicated no significant biases.CONCLUSION Semi-automated region growing algorithm for quantifying PE is reproducible using data from multiple scanners and is a suitable method for image analysis in multicenter clinical trials.Audrey E Kaufman Alison N Pruzan Ching Hsu Sarayu Ramachandran Adam Jacobi Indravadan Patel Lee Schwocho Michele F Mercuri Zahi A Fayad Venkatesh Mani 2018World Journal of Radiology2018,10,10:3
2Emerging plasmid-mediated quinolone resistance associated with the qnr gene in Klebsiella pneumoniae clinical isolates in the United States 显示文摘Wang M G Sahm D F Jacoby G A 2004Antimicrob Agents Chemother2004,48,4:1
3Identification of a glucocorticoid response element in the rat beta2-adrenergic receptor gene显示文摘Cornett L Hiller F Jacobi SE et at 1998Mol Pharmacol1998,54,6:1
4Size and Burden of Mental Disorders in Europe-a critical review and appraisal of 27 Studies显示文摘Wittchen H U Jacobi F 2005Eur Neuropsyehopharmacol2005,15,4:1
5Exogenous reelin prevents granule cell dispersion in experimental epilepsy显示文摘Martin C. Müller Matthias Osswald Stefanie Tinnes Ute H?ussler Anne Jacobi Eckart F?rster Michael Frotscher Carola A. Haas 2009Experimental Neurology2009,,2:1
6The relationship between migraine and mental disorders in a population-based sample显示文摘Ratcliffe GE Enns MW Jacobi F 2009Gen Hosp Psych2009,31,1:1
7Addition of dexmedetomidine to sedation regimens after cardiac surgery:an outcome analysis显示文摘DASTA J F JACOBI J SESTI A M 2006Phamacotherapy2006,26,6:1
8Plasmid-mediated quinolone resistance in clinical isolates of Escherichia coli from Shanghai,China显示文摘Wang M Tran JH Jacoby GA Zhang Y Wang F Hooper DC 2003Antimicrob Agents Chemother2003,47,7:1
9The impact of pressure biopsy of pan creatic lymph nodes with helium and carbon dioxide on port site and liver metastasis in BOP-induced pancreatic cancer in hamster显示文摘WENGER F A JACOBI C A KILIAN M 2001Clin Exp Metastasis2001,15,10:1
10Segregation patterns and heteroplasmy prevalence in Leber's hereditary optic neuropathy显示文摘Jacobi F K Leo-Kottler B Mittelviefhaus K 2001Invest Ophthalmol Vis Sci2001,42,6:1
11Opportunities and Challenges in Delivering Influenza Vaccine by Microneedle Patch 显示文摘Jacoby E Jarrahian C Hull H F 2015Vaccine2015,33,37:1
12Differential effects of epratuzumab on peripheral blood B cells of SLE patients versus normal controls 显示文摘JACOBI A M GOLDENBERG D M HIEPE F 2008Ann Rheum Dis2008,67,4:1
13Experimental study of theeffect of intra - abdominal pressure during laparoscopy on tumorgrowth and port site metasases 显示文摘Jacobi C A Wenger F A Ordeman J 1998Br J Surg1998,85,:1
14Effect of si- multaneous inhibition of epidermal growth factor recepror and cyclooxygenase 2 in HER - 2/neu positive breast cancer 显示文摘Lanza- Jacoby S Burd R Rosato F E Jr 2006Clin Cancer Res2006,12,201:1
15The nonpeptide angiotensin (1 7) receptor Mas agonist AVE 0991 attenuates heart failure induced by Myocardial infarction显示文摘Ferreira A J Jacoby B A Araujo C A Macedo F A Silva G A Almeida A P 2007Am J Physiol Heart Circ Physiol2007,292,:1
16MiRNA expres- sion profiles in chronic lymphocytic and acute lymphocytic leukemia显示文摘Zanette D L Rivadavia F Jacoby S 2007Brazilian Journal of Medical and Biological Research2007,40,2:1
17Mental disorders and asthma in the community显示文摘Goodwin RD Jacobi F Thefeld W 2003Arch Gen Psychiatry2003,60,:1
18Obstetric outcomes in women with sonographically identified uterine leiomyoma- ta 显示文摘Qidwai G I Caughey A B Jacoby A F 2006Obstet Gynecol2006,107,21:1
19The size and burden of mental disorders and other disorders of the brain in Europe 显示文摘WITFCHEN HU JACOBI F REHM J 2011Eur Neuropsychopharmacol2011,21,9:1
20The COX-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the Min mouse model of adenomatous polyposis显示文摘Jacoby R F Seibert K J Cole C E 2000Cancer Res2000,60,18:1
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