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| 1 | Schistosoma japonicum infection induces macrophage polarization显示文摘The role of macrophages(Mφ)as the first line of host defense is well accepted.These cells play a central role in orchestrating crucial functions during schistosomal infection.Thus,understanding the functional diversity of these cells in the process of infection as well as the mechanisms underlying these events is crucial for developing disease control strategies.In this study,we adopted a Mφpolarization recognition system.Ml macrophage was characterized by expressing CD16/32,IL-12 and iNOS.M2 macrophage was characterized by expressing CD206,IL-10 and arg-1.In vivo(mouse peritoneal macrophages of different infection stages were obtained)and in vitro(different 5.japonicum antigens were used to stimulate RAW264.7)were characterized by using the above mentioned system.NCA and ACA stimulated RAW264.7 express significantly higher levels of IL-12 while significantly higher levels of IL-10 were detected after soluble egg antigen(SEA)stimulation.The results showed that dramatic changes of antigen in the microenvironment before and after egg production led to macrophage polarization.Furthermore,through TLR blocking experiments,the TLR4 signaling pathway was found to play a role in the process of macrophage polarization toward Ml.Our data suggest that macrophage polarization during S.japonicum infection had significant effects on host immune responses to S.japonicum. | Jingwei Xu Hao Zhang Lin Chen Donghui Zhang Minjun Ji Haiwei Wu Guanling Wu | 2014 | The Journal of Biomedical Research2014，28，4： | 20 |
| 2 | Reversing drug resistance of soft tumor-repopulating cells by tumor cell-derived chemotherapeutic microparticles显示文摘颠倒使人重新住入肿瘤的房间(TRC ) 的药抵抗或起源的发展中的新奇途径像房间的癌症房间是迫切临床的需要改进癌症病人的结果。这里,我们显示出用肿瘤颠倒 TRC 的药抵抗的一条创新途径包含反肿瘤药的导出房间的 microparticles (T-MPs ) 。由比区分的癌症房间更可变形的优点, TRC 优先地收起 T-MPs 在进入房间以后释放反肿瘤药,它接着导致 TRC 的死亡。内在的机制包括防碍药流出并且支持这些药的原子入口。我们的调查结果在用有希望的临床的应用程序颠倒 TRC 的药抵抗在 T-MPs 的举起和一条新奇途径的有效性表明肿瘤房间柔软的重要性。 | Jingwei Ma Yi Zhang Ke Tang Huafeng Zhang Xiaonan Yin Yong Li Pingwei Xu Yanling Sun Ruihua Ma Tiantian Ji Junwei Chen Shuang Zhang Tianzhen Zhang Shunqun Luo Yang Jin Xiuli Luo Chengyin Li Hongwei Gong Zhixiong Long Jinzhi Lu Zhuowei Hu Xuetao Cao Ning Wang Xiangliang Yang Bo Huang | 2016 | Cell Research2016，26，6： | 17 |
| 3 | An in vivo study of the biodistribution of gold nanoparticles after intervaginal space injection in the tarsal tunnel显示文摘金 nanoparticles (AuNPs ) 的 biodistribution 是仔细与毒物学的效果有关并且因为他们的潜在的申请,担心大。与为液体运输的新奇解剖、组织学的结构的发现,然而,内在的机制包含了在在里面 AuNPs 的 vivo 运输和 biodistribution 要求进一步深入的调查。在当前的学习,在腱,容器,和神经纤维的一个焦点的点可以最佳地与另外的遥远的结缔组织连接的地方,我们在跗骨的隧道在 intervaginal 空间注射(ISI ) 以后在老鼠调查了 10-nm AuNPs 的 biodistribution。AuNPs 的静脉内的注射(IVI ) 用作控制。血和机关与诱导地联合的血浆团 spectrometry (ICPMS ) 为 Au 分发的定量分析在注射以后在 5, 15,和 30 min 并且在 1, 4, 12,和 24 h 被收集。IVI 和 ISI 产出显著地不同的结果:在在 ISI 以后的血的 AuNP 内容在 IVI 以后是比那低得多的;在肺,心,和肠是类似的;并且在皮和肌肉是更高的。这些调查结果被 AuNP 内容和相对机关 AuNP 分发比例的比率支持。我们表明的结果一快,直接并且发行量无关的 AuNP 器官运输小径,它可以改进我们生理、病理学的 biodistribution 的理解在生物系统处理。而且,这些结果提供新奇卓见进在里面 vivo 运输和 AuNPs 的 biodistribution,它可以导致新奇、有效治疗学并且管理策略。 | Xiaoli Shi Yuting Zhu Wenda Hua Yinglu Ji Qing Ha Xinxiao Han Yang Liu Jingwei Gao Qiang Zhang Sidi Liu Keli Ren Xiaochun Wu Hongyi Li Dong Han | 2016 | Nano Research2016，9，7： | 7 |
| 4 | Computer simulation of evacuation in underground coal mines显示文摘In order to study the evacuation behavior of miners during accidents,we analyzed the rational layout of a safe chamber,and improved evacuation efficiency.A visual model of evacuation was developed and used to simulate the evacuation process of mines,given their special underground environments.In our simulation,the working faces of a coal mine and nearby tunnels were divided into 0.5 m×0.5 m grids to reflect the location of occupants and obstacles.Based on a 'flow potential of the occupant',we determined the direction of movement and routes of occupants.In the model,evacuation speed changed as a function of crowd density,with an average speed of 1.30 m/s.The model also takes into account detection time of the disaster and the personnel response time.Evacuation time,exit flow rate and evacuation path were obtained by simulation.The results indicate that using simulation technology can present a more visual evacuation process and show the behavior of occupants.Our establishment of a mine safety evacuation system has merit as reference value. | JI Jingwei ZHANG Jlngyao CHEN Jinlin WU Shuang | 2010 | Mining Science and Technology2010，20，5： | 4 |
| 5 | Numerical simulation of fire development in a single compartment based on cone calorimeter experiments显示文摘The burning characteristics of several kinds of wood and polyurethane materials have been studied using cone calorimeter (CONE2A). A new and simple ignition criterion, heat release rate model and mass loss rate model are proposed based on experiments. Combined with these models, the zone-model of fire can be used to predict fire development in a single compartment according to the species of combustibles, their quantities and distribution. Calculated results show that this method is simple and feasible. | JI Jingwei, CHENG Yuanping, YANG Lizhong and FAN Weicheng( State Key Laboratory of Fire Science, University of Science and Technology of China, Hefei 230026, China College of Energy Science and Engineering, China University of Mining and Technology, Xuzhou 221008, China) | 2002 | Progress in Natural Science:Materials International2002，12，5： | 3 |
| 6 | Development of a PVDF sensor for potted seedling clamping force of vegetable transplanting显示文摘Aiming at the problems of loose bowl,nutritive bowl damage and planting leakage caused by lack of perception and detection of seedling clamping force in vegetable transplanting,a semi-micro-column structure sensor for measuring potted seedling clamping force was developed based on polyvinylidene fluoride(PVDF)piezoelectric film.The diameter of the semi-micro-column is 4 mm.The size of the force probe is 14 mm×30 mm,the encapsulation position of the force probe is 25 mm away from the tip of the seedling claw.The hardware circuit for sensor signal acquisition including pre-amplification module,power frequency notch module,low-pass filter module,processor module and power module was designed.The circuit completes charge-voltage conversion,clamping force signal amplification,power frequency signal elimination,vibration and noise elimination,and ensures the accurate acquisition of clamping force signal.In order to verify the sensor performance,sensor calibration tests and indoor experiments were carried out respectively.The calibration tests showed that the sensitivity of the clamping force sensor was 0.5264 V/N,the linearity was 4.74%,the accuracy was 6.51%,the hysteresis was 3.63%,and the range was 8 N under the impact of different waveforms and frequencies,which fully meet the accuracy requirements of the clamping force detection during transplanting.Indoor experiments showed that the clamping force sensor had good stability and adaptability under different seedling frequencies.The sensor can provide useful reference for the perception and detection of seedling clamping force and the feedback regulation of seedling clamping force. | Jiangtao Ji Jingwei Sun Xin Jin Mingyong Li Xinwu Du | 2019 | International Journal of Agricultural and Biological Engineering2019，12，5： | 3 |
| 7 | Advances in preparation,application in contaminant removal,and environmental risks of biochar-based catalysts:a review显示文摘As a carbon-rich material produced by pyrolysis of biomass,biochar features low cost,large specific surface area,and widely available feedstocks based on the functional diversity and environmental-friendly properties,it has received increasing attention in the fields of pollutant removal due to three win-win effects of water remediation,carbon sequestration and reutilization of wastes.To design excellent biochar-based catalysts for environmental applications,one must understand recent advances in the catalysts for contaminant removal.This review focuses on the current application of biochar-based catalysts in redox systems,Fenton-like systems,sonocatalytic systems and photocatalytic systems.Besides in-depth discussion in effects of preparation conditions on physicochemical characteristics of biochars,the review supplements new preparation technologies of biochar and biochar-based catalysts.Most importantly,the advantages/shortcomings,catalysis mechanisms,as well as the pollutant removal ability of different types of biochar-based catalysts are discussed.The environmental risks of the catalyst applications are also elaborated on.Future research on biochar-based catalyst production and its environmental applications is discussed.The review provides a good overview of the current advances of biochar-based catalysts in pollutant control and the future research directions. | Bowen Yang Jiawei Dai Yuan Zhao Jingwei Wu Caiya Ji Yuhu Zhang | 2022 | Biochar2022，4，1： | 2 |
| 8 | The calibration and initial results of the HeI D3 line flash spectrum obtained during the 2008 total solar eclipse显示文摘The flash spectra in the HeI D3 line were obtained during the 2008 total solar eclipse. This paper describes the instrument and the calibration of the obtained flash spectrum, and presents our initial results. The average integrated intensity is Eave = 8.13×1013 erg·cm-1· s-1·ster-1 at h = 1100 km, which confirms that the HeI D3 emission is negatively correlated with the solar activity. The surface brightness reaches a maximum of F ave = 8.25×105 erg·cm-2·s-1·ster-1 at about h ≈ (1290 ± 75) km and then decreases exponentially with height when h >1800 km with an exponential index β = 1.63×10-8 cm-1. | LI Hui JI HaiSheng NI HouKun ZHANG HaiYing ZHANG YaNan LIU HongRui DENG YuanYong WANG DongGuang DU QiuSheng ZHOU TuanHui LI JingWei SHEN JinHua | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，11： | 2 |
| 9 | Application of an ion-exchange model to the synthesis of fibrous titanate derivatives 显示文摘 | He Ming Feng Xin Lu Xiaohua Ji Xiaoyan Liu Chang Bao Ningzhong Xie Jingwei | 2003 | Journal of Chemical Engineering of Japan2003，36，10： | 1 |
| 10 | Phylogenetic distribution and predominant genotype of the avian infectious bronchitis vi- rus in China during 2008-2009 显示文摘 | Ji Jun Xie Jingwei Chen Feng | 2011 | Virol J2011，，8： | 1 |
| 11 | Mathematical model for prediction of pyrolysis and ignition of wood under external heat flux显示文摘The pyrolysis and ignition of combustible materials is an important aspect of the processes taking place in an unwanted fire. A prediction model presented in this paper is to study pyrolysis and ignition time of wood under external heat flux. The solution of the model provides the temperature at each point of the solid and the local solid conversion. And the time to ignition of the wood is predicted with the solution of surface temperature. In general, a good agreement between experimental and theoretical results is obtained. | CHEN Xiaojun, YANG Lizhong, JI Jingwei and DENG Zhihua(State Key Laboratory of Fire Science, University of Science and Technology of China, Hefei 230026, China) | 2002 | Progress in Natural Science:Materials International2002，12，11： | 0 |
| 12 | Teachers cooperation:team-knowledge distillation for multiple cross-domain few-shot learning显示文摘Although few-shot learning(FSL)has achieved great progress,it is still an enormous challenge especially when the source and target set are from different domains,which is also known as cross-domain few-shot learning(CD-FSL).Utilizing more source domain data is an effective way to improve the performance of CD-FSL.However,knowledge from different source domains may entangle and confuse with each other,which hurts the performance on the target domain.Therefore,we propose team-knowledge distllation networks(TKD-Net)to tackle this problem,which explores a strategy to help the cooperation of multiple teachers.Specifically,we distill knowledge from the cooperation of teacher networks to a single student network in a meta-learning framework.It incorporates task-oriented knowledge distillation and multiple cooperation among teachers to train an efficient student with better generalization ability on unseen tasks.Moreover,our TKD-Net employs both response-based knowledge and relation-based knowledge to transfer more comprehensive and effective knowledge.Extensive experimental results on four fine-grained datasets have demonstrated the effectiveness and superiority of our proposed TKD-Net approach. | Zhong JI Jingwei NI Xiyao LIU Yanwei PANG | 2023 | Frontiers of Computer Science2023，17，2： | 0 |
| 13 | Efficacy of Ganshuang granules(肝爽颗粒)on non-alcoholic fatty liver and underlying mechanism:a network pharmacology and experimental verification显示文摘OBJECTIVE:To investigate the potential pharmacological mechanisms of Ganshuang granules(肝爽颗粒,GSG)in treating non-alcoholic fatty liver(NAFLD).METHODS:All the active components and targets of GSG were retrieved from the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform.Protein-Protein interaction network,Kyoto Encyclopedia of Genes and Genomes and Gene Ontology function annotation of common targets were analyzed to predict the mechanisms of action of GSG in the treatment of NAFLD.Then,the mouse models of NAFLD were constructed in a diet-induced manner and treated with GSG.The levels of interleukin 6(IL-6),tumor necrosis factor-alpha(TNF-α)and phosphatidylinositol 3-kinase/protein kinase B(PI3K/AKT)pathway-related proteins in the liver of mice in each group were measured by enzyme linked immunosorbent assay and Western blot,respectively.RESULTS:Network pharmacology revealed a total of 159 potential targets of GSG for the treatment of NAFLD.Functional enrichment analysis indicated that the PI3K/AKT signaling pathway may be involved during GSG treatment of NAFLD.Further experiments showed that the significantly decreased alanine aminotransferase,aspartate aminotransferase,alkaline phosphatase,total cholesterol,triglyceride and low-density lipoprotein cholesterol levels in NAFLD model mice serum after GSG treatment,as well as the expression levels of IL-6 and TNF-αin the liver.Furthermore,drug intervention increased the protein expression levels of phosphorylated-PI3K(P-PI3K)and P-AKT in the liver of the model group mice,and decreased the protein expression level of sterol regulatory element-binding protein 1.CONCLUSION:We found that GSG is effective in treating NAFLD and the potential therapeutic targets may be involved in PI3K/AKT signaling pathway. | ZHI Guoguo SHAO Bingjie ZHENG Tianyan JI Shaoxiu LI Jingwei DANG Yanni LIU Feng WANG Dong | 2024 | Journal of Traditional Chinese Medicine2024，44，1： | 0 |
| 14 | Prophylaxis of posterior capsule opacification through autophagy activation with indomethacin-eluting intraocular lens显示文摘Posterior capsule opacification(PCO)is the most common long-term postoperative complication of cataract surgery,leading to secondary vision loss.Optimized intraocular lens(IOL)structure and appropriate pharmacological intervention,which provides physical barriers and biological inhibition,respectively,can block the migration,proliferation,and epithelial-mesenchymal transition(EMT)of lens epithelial cells(LECs)for PCO prophylaxis.Herein,a novel indomethacin-eluting IOL(INDOM-IOL)with an optimized sharper edge and a sustained drug release behavior was developed for PCO prevention.Indomethacin(INDOM),an ophthalmic non-steroidal anti-inflammatory drug(NSAID)used for postoperative ocular inflammation,was demonstrated to not only be able to suppress cell migration and down-regulate the expression of cyclooxygenase-2(COX-2)and EMT markers,including alpha-smooth muscle actin(α-SMA)and cyclin D1,but also promote the autophagy activation in LECs.Additionally,autophagy was also verified to be a potential therapeutic target for the down-regulation of EMT in LECs.The novel IOL,serving as a drug delivery platform,could carry an adjustable dose of hydrophobic indomethacin with sustained drug release ability for more than 28 days.In the rabbit PCO model,the indomethacin-eluting IOL showed excellent anti-inflammatory and anti-PCO effects.In summary,indomethacin is an effective pharmacological intervention in PCO prophylaxis,and the novel IOL we developed prevented PCO in vivo under its sustained indomethacin release property,which provided a promising approach for PCO prophylaxis in clinical application. | Xiaobo Zhang Jing Wang Jingwei Xu Wen Xu Yin Zhang Chenqi Luo Shuang Ni Haijie Han Xingchao Shentu Juan Ye Jian Ji Ke Yao | 2023 | Bioactive Materials2023，，5： | 0 |
| 15 | Design and experiment of the environment control system for the industrialized production of Agaricus bisporus显示文摘Environment parameters are the main factors affecting the growth and development of Agaricus bisporus.Because of the requirements of environmental conditions for high-efficiency industrialized production of Agaricus bisporus,equipments for environment control were developed.Based on the variable operating equipment,a multi-factor fuzzy controller was designed to realize the comprehensive control of ambient temperature,humidity,CO2 concentration,and the temperature and moisture of the compost.The test results showed that the temperature control error was less than±0.5°C and the response speed was more than 0.5°C/h;The control error of ambient humidity was less than±2%RH,and the response speed was more than 9%RH per hour;The moistures at different points in compost ranged from 50%to 70%with a standard deviation of 4.04.The control accuracy of environmental CO2 concentration was within 200μmol/mol.The overall performance of the control system was stable and reliable,which could meet the requirements of environment factors for the growth of Agaricus bisporus.The system can provide technical support and reference for the automatic and precise control of the environment during the industrialized production of Agaricus bisporus. | Kaixuan Zhao Xuefeng Zhu Hao Ma Jiangtao Ji Xin Jin Jingwei Sun | 2021 | International Journal of Agricultural and Biological Engineering2021，14，1： | 0 |
| 16 | Sulige Gas Field super project显示文摘Owner:Petro China Changqing Oilfield Company Design unit:Petro China Changqing Oilfield Company Construction unit:Petro China Changqing Oilfield Company,CNPC Chuanqing Drilling Engineering Company Limited,CNPC Greatwall Drilling Company。 | Wenrui HU Jingwei BAO Pengcheng JI | 2017 | Frontiers of Engineering Management2017，4，3： | 0 |
| 17 | Angioarchitecture and prognosis of pediatric intracranial pial arteriovenous fistula显示文摘Objective Pial arteriovenous fistulas(PAVFs)are rare and mostly observed in children.However,the overall angioarchitecture,clinical features,treatments and long-term prognosis for pediatric patients remain unclear.Methods Clinical data of consecutive 42 pediatric PAVFs were documented and analysed.According to the differences of age distribution and clinical features,they were split into a younger group(≤3 years old;20 cases)and an older group(3-14 years old;22 cases).Results Their mean age was 4.9±3.9 years,and the mean preoperative modified Rankin Scale(mRS)score was 1.64±1.57.Fourteen patients(33.3%)were asymptomatic,followed by epilepsy(21.4%),intracranial haemorrhage(16.7%),hydrocephalus(9.5%),developmental delay(7.1%),intermittent headache(7.1%)and congestive heart failure(4.8%).Annual bleeding rate and rebleeding rate before treatment reached 3.86%and 3.17%.Poor venous drainage including sinus dynamic obstruction(21 cases,50.0%)and sinus occlusion(17 cases,40.48%)were found with high frequency among these patients.Finally,33 cases were cured(78.57%),and 4 cases faced surgery-related complications(9.52%).During 24-140 months’follow-up,the mean mRS score reduced to 0.57±0.40.However,only 22 cases(52.38%)recovered to absolutely normal,and poor venous drainage was the risk factor for patients’incomplete recovery(p=0.028,Exp(B)=14.692,95%CI 1.346 to 160.392).Compared with the older group,younger group showed more chronic symptoms,more secondary pathological changes,more times treatment and worse prognosis(p=0.013,0.002,0.000 and 0.032,respectively).Conclusions Pediatric PAVF has different angioarchitectures,clinical features and prognoses in different age groups.Poor venous drainage is an important factor leading to poor prognosis,and it accounts for incomplete recovery in nearly half of patients. | Jingwei Li Zhenlong Ji Jiaxing Yu Jian Ren Fan Yang Lisong Bian Xinglong Zhi Guilin Li Hongqi Zhang | 2023 | Stroke & Vascular Neurology2023，8，4： | 0 |
| 18 | Digitally programmable organic light‐emitting tetrodes显示文摘Limited to the structure of traditional light‐emitting devices,electronic devices that can directly convert machine language into human visual information without introducing any back‐end circuit are still not easy to achieve.Based on a specially designed three‐phase co‐planar electrode structure,a new type of three‐phase alternating current driven organic light‐emitting device with the integration of emission and control functions,full‐color tunability and simple device structure is demonstrated in this study.We integrate the light‐emitting function of color‐tunable light‐emitting devices and the switching of three triodes in a single three phase organic light‐emitting device.The state control of luminous color and luminance intensity merely requires the introduction of a kind of machine language,that is an easy‐to‐program 6‐bit binary number coded digital signals.The color adjustable area covers 66%of the color triangle of the National Television System Committee.Such simple and easy‐to‐integrate light‐emitting system has great potential applications in the next‐generation man‐machine interface. | Junpeng Ji Biao Yang Chaohong Zhang Yulu Cai Jingwei Chen Changbin Zhao Tao Wang Lijie Wu Ming Liu Junwu Bai Jiangfeng Wang Zhongbin Wu Shufen Chen Haifeng Ling Zhongfu An Yonghua Chen Jianpu Wang Wei Huang Hong Meng | 2023 | SmartMat2023，4，2： | 0 |
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