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| 1 | 子宫颈上皮内瘤变或原位腺癌的处理(2006年版)显示文摘2006年9月18—19日,146名代表29个组织和专业学会的专家在Bethesda聚会,修改制订了有关如何处理宫颈癌筛查异常结果妇女的以循证医学为依据的共识指南。有关低度宫颈上皮内瘤变(cervical intraepithelial neoplasia,CIN)的处理,变化较大。以往,需要根据阴道镜检查结果是否满意进行处理,对所有的CIN1妇女均可以采用破坏或者切除疗法。在新的指南中,不论阴道镜检查满意与否,对因低度宫颈细胞学结果转诊而明确的CIN1,细胞学随访是唯一的处理建议。 | 李志刚 Thomas C.Wright L.Stewart Massad Charles J.Dunton Mark Spitzer Edward J.Wilkinson Diane Solomon | 2008 | 循证医学2008，8，5： | 4 |
| 2 | Decontamination of laryngoscopes: a survey of national practice[A summary ]显示文摘 | M. D.Esler L. C.Baines D. J.Wilkinson R. M.Langford | 2002 | Anaesthesia2002，，6： | 2 |
| 3 | Polyfunctional T cells in human tuberculosis显示文摘 | Katalin A.Wilkinson Robert J.Wilkinson | 2010 | Eur J Immunol2010，，8： | 1 |
| 4 | 英国输血过程的国家审查显示文摘为改进输血工作质量和文件记录,英国皇家医师协会疗效评审部(CEEU)与英国血液学会、英国输血协会以及美国皇家病理学协会,根据英国皇家医师协会1995年的资料汇编,共同制定了9项审查方案。 1995年9月,国家卫生部(NHSE)资助了国家审查从两项审查方案开始。一项是对机构的输血工作审查,另一项是对输血的记录审查。虽然根据英国血液标准委员会(BCSH)关于医院输血记录指南,审查方案有了不明确的标准,但在此项目开展以前,并没有制定明确的标准。该项研究的目的是收集基本数据,以便制定严格有效的输血治疗标准和制定一个全国性的输血治疗审查质量的检测方法,修订全国的输血指南。 | M.F.Murphy J.Wilkinson D.Lowe etal 李执如 孙启凤 季阳 | 2003 | 国外医学(输血及血液学分册)2003，26，4： | 1 |
| 5 | Cold dwell behaviour of Ti6Al alloy:Understanding load shedding using digital image correlation and dislocation based crystal plasticity simulations显示文摘Digital image correlation(DIC)and dislocation based crystal plasticity simulation were utilised to study cold dwell behaviour in a coarse grain Ti-6Al alloy at 3 different temperatures up to 230℃.Strains extracted from large volume grains were measured during creep by DIC and were used to calibrate the crystal plasticity model.The values of critical resolved shear stresses(CRSS)of the two main slip systems(basal and prismatic)were determined as a function of temperature.Stress along paths across the boundaries of four grain pairs,three“rogue”grain pairs and one“non-rogue”grain pair,were determined at different temperatures.Large load shedding was observed in one of the“rogue”grain pairs,where a stress increment during the creep period was found in the“hard”grain.A minor load shedding mechanism was observed in two non-typical“rogue”grain pairs,in which the plastic deformation is nonuniform inside the grains and geometrically necessary dislocations accumulate in the centre of the grains.At elevated temperatures,120℃was found to be the worst case scenario as the stress difference at the grain boundaries of these four grain pairs was found to be the largest among the three temperatures analysed.The origin of this critical temperature is debated in the literature and it is investigated for the first time in the present work by analysing the simultaneous effects of the geometrically necessary dislocations(GND)and the strain rate sensitivity(SRS)of the slip systems.The analysis shows that the combined effects of the peak SRS of both prismatic and basal slip systems at 80℃and of the increase of the spread of the GND distribution around the grain boundary at higher temperatures are the origin of the observed worst case scenario. | Yi Xiong NicolòGrilli Phani S.Karamched Bo-Shiuan Li Edmund Tarleton Angus J.Wilkinson | 2022 | Journal of Materials Science & Technology2022，，33： | 1 |
| 6 | Incorrect and incomplete coding and classification of diabetes: a systematic review显示文摘 | M. A.Stone J.Camosso‐Stefinovic J.Wilkinson S.De Lusignan A. T.Hattersley K.Khunti | 2010 | Diabetic Medicine2010，，5： | 1 |
| 7 | Macroscopic analysis of time dependent plasticity in Ti alloys显示文摘Cold dwell fatigue is the critical technological issue in Ti alloys used in the cooler front sections of aerospace jet engines.When subjected to a sustained load(stress dwell),the lifetime of these Ti components can be drastically reduced by as much as an order of magnitude[1–4].Without a clear understanding of the effect,safety concerns are raised. | Yi Xiong Phani S.Karamched Chi-Toan Nguyen David M.Collins Christopher M.Magazzeni Edmund Tarleton Angus J.Wilkinson | 2022 | Journal of Materials Science & Technology2022，，29： | 0 |
| 8 | 黄曲霉毒素B_1疫苗通过粘膜给药时的免疫反应显示文摘使用粘膜型疫苗促使仔鸡产生血清免疫球蛋白 G(Ig G)和肠分泌性免疫球蛋白 A(Ig A) ,以达到防止黄曲霉毒素 B1(AFB)中毒的目的。AFB和载体蛋白 (牛血清清蛋白(BSA)或猪甲状腺球蛋白 )偶联后分别用于制备疫苗和作为酶联免疫吸附试验 (EL ISA)的包被抗原。将 7日龄肉仔鸡分成 10组 ,分别用以下 4种免疫制剂免疫 :1AFB- BSA接含物 ,2 AFB- BSA与大肠杆菌热不稳定性肠毒素重组子的 B亚基结合物 (r L T- B) ,3AFB- BSA与 r L T- B的混合物 ,4AFB- BSA与霍乱毒素 (CT)的混合物。每种疫苗分口腔、直肠、腹膜 3种方式给药 ,2星期后进行加强免疫 ,每星期收集血清和粪便样 ,并用同型特异性 EL ISA分析样品。试验结果表明 ,3种免疫方式都明显引起了肉仔鸡血清 Ig G的免疫反应 ,其中腹膜途径的免疫反应最强烈 ;AFB- BSA接合物与r L T- B共同给药能加强血清 Ig G对 AFB- BSA接合物的免疫反应 ,但是 AFB- BSA与 r L T- B共价偶联或与 CT共同给药则不能加强试验鸡血清 Ig G的免疫反应 ;在粪便上清液中检测到了抗 CT和抗 r L T- B的分泌性抗体 Ig A,而未检测到抗 AFB的抗体 ;所有 12个处理的抗 AFB血清 Ig G水平都很高 ,包括无佐剂口服给药方式任一种方法通过对游离 AFB进行简单的免疫截段都能使仔鸡产生不同水平的免疫? | J.Wilkinson 张幸开 | 2004 | 中国畜牧兽医2004，31，9： | 0 |
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