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| 1 | 肝硬化胃食管静脉曲张与曲张破裂出血的治疗和预防显示文摘这份指南已经被美围肝病学会和美国胃食管医师协会所认可,体现了两个协会对胃底食管静脉曲张与曲张破裂出血的治疗和预防的观点: | Guadalupe Garcia-Tsao Arun J.Sanyal Norman D.Grace William Carey 范文哲 陈斌 向贤宏 黄勇慧 杨建勇 | 2010 | 影像诊断与介入放射学2010，19，5： | 7 |
| 2 | Role of insulin resistance and hepatic steatosis in the progression of fibrosis and response to treatment in hepatitis C显示文摘 | Arun J.Sanyal | 2011 | Liver International2011，，： | 1 |
| 3 | Role of insulin resistance and hepatic steatosis in the progression of fibrosis and response to treatment in hepatitis C显示文摘 | Arun J.Sanyal | 2011 | Liver International2011，，： | 1 |
| 4 | Review article: the prothrombin time test as a measure of bleeding risk and prognosis in liver disease显示文摘 | A.TRIPODI S. H.CALDWELL M.HOFFMAN J. F.TROTTER A. J.SANYAL | 2007 | Alimentary Pharmacology & Therapeutics2007，，2： | 1 |
| 5 | Foregut bypass vs.restrictive bariatric procedures for nonalcoholic fatty liver disease:a meta-analysis of 3,355 individuals显示文摘Background:Bariatric surgery represents an important treatment option for severely obese patients with nonalcoholic fatty liver disease(NAFLD).However,there remains inadequate data regarding the effects of different bariatric procedures on various NAFLD parameters,especially for histological outcomes.Thus,this meta-analysis aimed to compare the effects of restrictive bariatric procedures and foregut bypass on the metabolic,biochemical,and histological parameters for patients with NAFLD.Methods:Medline and Embase were searched for articles relating to bariatric procedures and NAFLD.Pairwise meta-analysis was conducted to compare efficacy of bariatric procedures pre-vs.post-procedure with subgroup analysis to further compare restrictive against foregut bypass procedures.Results:Thirty-one articles involving 3,355 patients who underwent restrictive bariatric procedures(n=1,460)and foregut bypass(n=1,895)were included.Both foregut bypass(P<0.01)and restrictive procedures(P=0.03)significantly increased odds of fibrosis resolution.Compared to restrictive procedures,foregut bypass resulted in a borderline non-significant decrease in fibrosis score(P=0.06)and significantly lower steatosis score(P<0.001).For metabolic parameters,foregut bypass significantly lowered body mass index(P=0.003)and low-density lipoprotein(P=0.008)compared to restrictive procedures.No significant differences were observed between both procedures for aspartate aminotransferase(P=0.17)and alkaline phosphatase(P=0.61).However,foregut bypass resulted in significantly lower gamma-glutamyl transferase than restrictive procedures(P=0.01)while restrictive procedures resulted in significantly lower alanine transaminase than foregut bypass(P=0.02).Conclusions:The significant histological and metabolic advantages and comparable improvements in biochemical outcomes support the choice of foregut bypass over restrictive bariatric procedures in NAFLD management. | Wen Hui Lim Snow Yunni Lin Cheng Han Ng Darren Jun Hao Tan Jieling Xiao Jie Ning Yong Phoebe Wen Lin Tay Nicholas Syn Yip Han Chin Kai En Chan Chin Meng Khoo Nicholas Chew Roger S.Y.Foo Asim Shabbir Eunice X.Tan Daniel Q.Huang Mazen Noureddin Arun J.Sanyal Mohammad Shadab Siddiqui Mark D.Muthiah | 2023 | Hepatobiliary Surgery and Nutrition2023，12，5： | 0 |
| 6 | The transcontinental variability of nonalcoholic fatty liver disease显示文摘Aim:To compare the phenotype of lean versus overweight(OW)and obese(OB)subjects with non-alcoholic fatty liver disease(NAFLD)across multiple continents.Methods:A retrospective study of histologically defined subjects from a single center each in France(Fr),Brazil(Br),India(In)and United States(US)was performed.Results:A total of 70 lean[body mass index(BMI)<25 kg/m2]subjects(Fr:Br:In:US:16:19:22:13)with NAFLD were compared to 136 OW(BMI>25 kg/m2,BMI<29 kg/m2)(n=28:33:52:23)and 224 OB subjects(BMI>29 kg/m2)(n=81:11:22:103).Lean French subjects had the lowest incidence of type 2 diabetes while those from Brazil(P<0.01)had the highest.Lean subjects had similar low-density lipoprotein-cholesterol,but higher high-density lipoprotein-cholesterol compared to obese subjects in all regions.In both lean and obese subjects,there were both insulin-sensitive and insulin-resistant subjects.Lean French subjects were most insulin-sensitive while those from Brazil were mostly insulin-resistant.For each weight category,subjects from India were more insulin-sensitive than those from other regions.Disease activity increased from lean to overweight to obese in France but was similar across weight categories in other regions.Conclusion:The phenotype of NAFLD in lean subjects varies by region.Some obese subjects with NAFLD are insulin-sensitive.We hypothesize that genetics and region-specific disease modifiers account for these differences. | Claudia P.Oliveira Angelo Paredes Mohammed Siddiqui Lawrence Serfaty Abhijit Chowdhury Jose Tadeu Stefano Denise Siqueira Vanni Sherry Boyett Arun J.Sanyal | 2020 | Hepatoma Research2020，6，10： | 0 |
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