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| 1 | Biological activities and potential health benefits of bioactive peptides derived from marine organisms显示文摘 | Dai-Hung Ngo Thanh-Sang Vo Dai-Nghiep Ngo Isuru Wijesekara Se-Kwon Kim | 2012 | International Journal of Biological Macromolecules2012，，4： | 2 |
| 2 | Development and biological activityof marine-derived bioactive peptides :A review 显示文摘 | Se-Kwon K Isuru W | 2010 | Journal ofFunctional Foods2010，，2： | 1 |
| 3 | The Ubiquitin Ligase Mul1 Induces Mitophagy in Skeletal Muscle in Response to Muscle-Wasting Stimuli显示文摘 | Sudarsanareddy Lokireddy Isuru W. Wijesoma Serena Teng Sabeera Bonala Peter D. Gluckman Craig McFarlane Mridula Sharma Ravi Kambadur | 2012 | Cell Metabolism2012，，5： | 1 |
| 4 | Development and biologi- cal activities of marine - derived bioactive peptides : A review 显示文摘 | Se - Kwon Kim Isuru Wijesekara | 2010 | Journal of Functional Foods2010，2，1： | 1 |
| 5 | Biological activities and potential health benefits of sulfated polysaccharides derived from marine algae显示文摘 | Isuru Wijesekara Ratih Pangestuti Se-Kwon Kim | 2011 | Carbohydrate Polymers2011，84，： | 1 |
| 6 | Development and biological activities of marine-derived bioactive peptides : A review 显示文摘 | Se-kwon K Isuru W | 2010 | Journal of Functional Foods2010，2，1： | 1 |
| 7 | Development and biological activities of marine-derived bioactive peptides: A review显示文摘 | Se-Kwon Isuru Wijesekara | 2010 | Journal of Functional Foods2010，2，1： | 1 |
| 8 | Phlorotannins as bioactive agents from brown algae显示文摘 | Yong-Xin Li Isuru Wijesekara Yong Li Se-Kwon Kim | 2011 | Process Biochemistry2011，，12： | 1 |
| 9 | Digital Twin in biomanufacturing:challenges and opportunities towards its implementation显示文摘The domain of industrial biomanufacturing is enthusiastically embracing the concept of Digital Twin,owing to its promises of increased process efficiency and resource utilisation.However,Digital Twin in biomanufacturing is not yet clearly defined and this sector of the industry is falling behind the others in terms of its implementation.On the other hand,some of the benefits of Digital Twin seem to overlap with the more established practices of process control and optimization,and the term is vaguely used in different scenarios.In an attempt to clarify this issue,we investigate this overlap for the specific case of fermentation operation,a central step in many biomanufacturing processes.Based on this investigation,a framework built upon a five-step pathway starting from a basic steady-state process model is proposed to develop a fully-fledged Digital Twin.For demonstration purposes,the framework is applied to a bench-scale second-generation ethanol fermentation process as a case study.It is proposed that the success or failure of a fully-fledged Digital Twin implementation is determined by key factors that comprise the role of modelling,human operator actions,and other propositions of economic value. | Isuru A.Udugama Pau C.Lopez Carina L.Gargalo Xueliang Li Christoph Bayer Krist V.Gernaey | 2021 | Systems Microbiology and Biomanufacturing2021，1，3： | 1 |
| 10 | Purification and identification of antihypertensive peptides from seaweed pipefish(syngnathus schlegeli)muscle protein hydrolysate显示文摘 | Isuru Wijesekara Zhong-Ji Qian BoMi Ryu | 2011 | Food Research International2011，44，： | 1 |
| 11 | Angiotensin-1-converting enzyme (ACE) inhibitors from marine resources:Prospects in the pharmaceutical industry显示文摘 | ISURU WIJESEKARA SE-KWON KIM | 2010 | Marine Drugs2010，8，4： | 1 |
| 12 | Biological activities and potential health benefits of sulfated polysaccharides derived from marine algae显示文摘 | Isuru Wijesekara Ratih Pangestuti Se-Kwon Kim | 2010 | Carbohydrate Polymers2010，，1： | 1 |
| 13 | Phlorotannins as bioactive agents from brown algae显示文摘 | Yong-Xin Li Isuru Wijesekara Yong Li Se-Kwon Kim | 2011 | Process Biochemistry2011，，12： | 1 |
| 14 | Biological activities and potential health benefits of sulfated polysaccharides derived from marine algae显示文摘 | Isuru Wijesekara Ratih Pangestuti Se-Kwon Kim | 2011 | Carbohydrate Polymers2011，84，： | 1 |
| 15 | Cinnamomum zeylanicum and Curcuma longa incorporated dairy yoghurts with hindered glycaemic properties for healthy people显示文摘This study mainly compare glycaemic responses of a control yoghurt(typical dairy yoghurt)against two novel yoghurt products with added spices oleoresins(Cinnamon yoghurt-Cinnamomum zeylanicum,turmeric yoghurt-Curcuma longa)using 16 healthy volunteers in a randomized crossover study.Blood glucose concentrations were measured at fasting state and 30,45,60,90,120 min following the ingestion,using a Blood Glucose Monitoring System and blood glucose response curves were plotted.Nutritional and physicochemical properties were also compared and no significant differences(P>0.05)were observed between novel yoghurts and the control within the storage period.Significant reductions in peak blood glucose concentration and area under the curve(AUC)(P<0.05)for both novel products compared to standard dairy yoghurt was observed;revealing the reduction of glycaemic impact by spice ingredients.Peak reductions of glucose concentration for cinnamon yoghurt was 9.61%,for turmeric yoghurt was 9.26%;they were considerably lower compared to the control.Mean peak serum glucose concentration for control,cinnamon yoghurt and turmeric yoghurt were(113.38±6.39),(102.50±6.00),(102.88±5.38)mg/dL respectively and mean AUC were(11951±523),(11012±611),(10941±530)(mg/dL)·min respectively.Hence novel yoghurt products are proven to be excellent sources in reducing postprandial blood glucose responses.©2021 Beijing Academy of Food Sciences.yoghuart products sae proven to be excellent sources in reducing postprandial blood ghncose Tesponses. | Dayani Pavalakumar Madhura Jayasinghe Maharsha Edirisinghe Isuru Wijesekara Subhashinie Senadheera | 2021 | Journal of Future Foods2021，1，1： | 0 |
| 16 | Comparison of blood glucose responses by cane sugar(Saccharum offi cinarum)versus coconut jaggery(Cocos nucifera)in type 2 diabetes patients显示文摘Type 2 diabetic mellitus is a predominant metabolic disorder that has a direct impact on human health.Although scientific data are deficit,coconut jaggery has been suggested as a better alternative for cane sugar by some individuals.This study was conducted to assess the credibility of this claim.Coconut jaggery was prepared at Coconut Research Institute,Sri Lanka and nutritional composition of coconut jaggery was compared with cane sugar using standard methods.Significantly higher(P<0.05)moisture(8.92±0.22)%,ash(2.09±0.33)%,protein(1.91±0.28)%,fat(0.14±0.02)%and fiber(0.05±0.03)%contents were observed in coconut jaggery compared to cane sugar.The total starch and total sugar content of the coconut jaggery was significantly(P<0.05)lower than that of the cane sugar.Forty-three patients(Male:16,Female:27)with type 2 diabetes from the Endocrinology unit,National Hospital Colombo,Sri Lanka were voluntarily engaged in the study,subjected to an initial health screening.Then,determination of postprandial blood glucose responses after intake of the standard(glucose),cane sugar and coconut jaggery.Average age of the selected group was(48.19±7.95)years and they were all overweight(BMI>23.0).The mean fasting blood glucose level and HbA1c of the subjects were(149.05±54.88)mg/dL and(9.170±2.022)%,respectively.There was no significant difference(P>0.05)in peak blood glucose concentrations or incremental area under the curve in blood glucose response of two test food.Therefore,coconut jaggery cannot be considered as a healthy substitute for cane sugar in type 2 diabetic patients. | Hewa Pathiranage Dilani Thilanka Hewa Pathirana Isuru Wijesekara Loku Liyana Waduge Chandi Yalegama Chaminda Garusinghe Madhura Arunoda Jayasinghe Kande Pramuditha Waidyarathne | 2022 | Journal of Future Foods2022，2，3： | 0 |
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