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| 1 | Minimally invasive surgery for gastric cancer: A comparison between robotic, laparoscopic and open surgery显示文摘AIM To investigate the role of minimally invasive surgery for gastric cancer and determine surgical, clinical, and oncological outcomes.METHODS This is a propensity score-matched case-control study, comparing three treatment arms: robotic gastrectomy(RG), laparoscopic gastrectomy(LG), open gastrectomy(OG). Data collection started after sharing a specific study protocol. Data were recorded through a tailored and protected web-based system. Primary outcomes: harvested lymph nodes, estimated blood loss, hospital stay, complications rate. Among the secondary outcomes, there are: operative time, R0 resections, POD of mobilization, POD of starting liquid diet and soft solid diet. The analysis includes the evaluation of type and grade of postoperative complications. Detailed information of anastomotic leakages is also provided.RESULTS The present analysis was carried out of 1026 gastrectomies. To guarantee homogenous distribution of cases, patients in the RG, LG and OG groups were 1:1:2 matched using a propensity score analysis with a caliper = 0.2. The successful matching resulted in a total sample of 604 patients(RG = 151; LG = 151; OG = 302). The three groups showed no differences in all baseline patients characteristics, type of surgery(P = 0.42) and stage of the disease(P = 0.16). Intraoperative blood loss was significantly lower in the LG(95.93 ± 119.22) and RG(117.91 ± 68.11) groups compared to the OG(127.26 ± 79.50, P = 0.002). The mean number of retrieved lymph nodes was similar between the RG(27.78 ± 11.45), LG(24.58 ± 13.56) and OG(25.82 ± 12.07) approach. A benefit in favor of the minimally invasive approaches was found in the length of hospital stay(P < 0.0001). A similar complications rate was found(P = 0.13). The leakage rate was not different(P = 0.78) between groups.CONCLUSION Laparoscopic and robotic surgery can be safely performed and proposed as possible alternative to open surgery. The main highlighted benefit is a faster postoperative functional recovery. | Amilcare Parisi Daniel Reim Felice Borghi Ninh T Nguyen Feng Qi Andrea Coratti Fabio Cianchi Maurizio Cesari Francesca Bazzocchi Orhan Alimoglu Johan Gagnière Graziano Pernazza Simone D'Imporzano Yan-Bing Zhou Juan-Santiago Azagra Olivier Facy Steven T Brower Zhi-Wei Jiang Lu Zang Arda Isik Alessandro Gemini Stefano Trastulli Alexander Novotny Alessandra Marano Tong Liu Mario Annecchiarico Benedetta Badii Giacomo Arcuri Andrea Avanzolini Metin Leblebici Denis Pezet Shou-Gen Cao Martine Goergen Shu Zhang Giorgio Palazzini Vito D'Andrea Jacopo Desiderio | 2017 | World Journal of Gastroenterology2017，23，13： | 17 |
| 2 | Dexmedetomidine decreases emergence agitation in pediatric patients after sevoflurane anesthesia without surgery 显示文摘 | Isik B Arslan M Tunga A D | 2006 | Paediatr Anaesth2006，16，7： | 1 |
| 3 | A preferable technique for protecting the inferior alveolar nerve:coronectomy显示文摘 | Dolanmaz D Yildirim G Isik K | 2009 | J Oral i Maxillofac Surg2009，67，8： | 1 |
| 4 | Biological treatment of acid dyeing waste water using a sequential anaerobic/aerobic reactor sys- tem显示文摘 | ISIK M SPONZA D T | 2006 | Enzyme and Microbial Technology2006，38，7： | 1 |
| 5 | Comparison of classifica- tion systems for congenital melanoeytic nevi显示文摘 | Turkmen A Isik D Bekereeioglu M | 2010 | Dermatol Surg2010，36，10： | 1 |
| 6 | Decolorization of azo dyes under batch anaerobic and sequential anaerobic/aerobic conditions显示文摘 | Isik M Sponza D T | 2004 | Environ Sci Health Past A2004，39，4： | 1 |
| 7 | Comparison of the rate of palatal fistulation after two-flap and four-flap palatoplasty 显示文摘 | Bekerecioglu M Isik D Bulut O | 2005 | Scand J Plast Reconstr Surg Hand Surg2005，39，5： | 1 |
| 8 | Dexmedetomidine decreases emergence agitation in pediatric patients after sevoflurane anesthesia without surgery显示文摘 | ISIK B ARSLAN M TUNGA A D | 2006 | Paediatr Anaesth2006，16，7： | 1 |
| 9 | Comparison of classification systems for congenital melanocytic nevi显示文摘 | Turkmen A Isik D Bekerecioglu M | | 0，，10： | 1 |
| 10 | Fuzzy-based congestion control for wireless multimedia sensor networks显示文摘 | Sonmez C Incel O D Isik S | 2014 | EURASIP Journal on Wireless Communications and Networking2014，2014，1： | 1 |
| 11 | Severe hyponatremia due to escitalopram treatment in an elderly adult with Alzheimer' s disease显示文摘 | Pinar M D Isik A T | 2014 | J Am Geriat Society2014，62，12： | 1 |
| 12 | Buried and trapped penis: a case report显示文摘 | Isik D Isik Y Peker E | 2010 | Andrologia2010，42，4： | 1 |
| 13 | Comparison of octreotide LAR and lanreotide autogel as post-operative medical treatment in acromegaly 显示文摘 | Tutuncu Y Berker D Isik S | 2012 | Pituitary2012，15，3： | 1 |
| 14 | Frozen yogurt with added inulin and isomalt显示文摘 | ISIK U BOYACIOGLU D CAPANOGLU E | 2011 | Journal of DairyScience2011，94，4： | 1 |
| 15 | Thyrotropin secreting pituitary adenoma accompanying a silent somatotropinoma显示文摘 | Berker D Isik S Aydin Y | 2011 | Turk Neuro- surg2011，21，3： | 1 |
| 16 | Substrate romoval kinetics in an upflow an- aerobic sludge blanket reactor decolorising simulated textile wastewater显示文摘 | Isik M Sponza D T | 2005 | Process Biochemistry2005，40，34： | 1 |
| 17 | Prevalence of incidental thyroid cancer and its ultrasonographic features in subcentimeter thyroid nodules of patients with hyperthyroidism显示文摘 | Berker D Isik S Ozuguz U | 2011 | Endocrine2011，39，1： | 1 |
| 18 | A preferable technique for protecting the inferior alveolar nerve:coronectomy显示文摘 | Dolanmaz D Yildirim G Isik K | | 0，，06： | 1 |
| 19 | Effect of 2 flap designs on postoperative pain and swelling after impacted third molar surgery显示文摘 | Dolanmaz D Esen A Isik K | 2013 | Oral Surg Oral Med Oral Pathol Oral Radiol2013，116，4： | 1 |
| 20 | A comparative study of dental arch widths: Extraction and non-extraction treat- ment显示文摘 | Isik F Sayinsu K Nalbantgil D | 2005 | Eur J Orthod2005，27，6： | 1 |
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