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3篇 您的检索式:作者名="Isidro Machado"
    题名 作者 年代 出处 被引量
1Superficial EWSR1 -negative undifferentiated small round cell sarcoma with CIC/ DUX4 gene fusion: a new variant of Ewing-like tumors with locoregional lymph node metastasis显示文摘Isidro Machado Julia Cruz Javier Lavernia Luis Rubio Jorge Campos María Barrios Camille Grison Virginie Chene Gaelle Pierron Olivier Delattre Antonio Llombart-Bosch 2013Virchows Archiv2013,,6:1
2Pancreatic adenosquamous carcinoma and intraductal papillary mucinous neoplasm in a CDKN2A germline mutation carrier显示文摘A 69-year-old woman from a kindred with familial atypical multiple mole melanoma and carrier of a germline mutation in CDKN2A, presented with abdominal pain caused by a solid-cystic pancreatic mass. The patient had an abdominal computed tomography three years before in which there was no evidence of pancreatic lesion. The endoscopic ultrasound guided fine needle aspiration showed adenocarcinoma with squamous component. After surgical resection the final diagnosis was adenosquamous pancreatic carcinoma(ASPC) arising in an intraductal papillar mucinous neoplasm(IPMN). Adenosquamous carcinomas are uncommon in the pancreas and have rarely been described in association with IPMNs. It has worse prognosis than the ordinary pancreatic ductal adenocarcinoma and some distinct features. We review the clinical, imaging, pathologic and molecular aspects of ASPC. Differential diagnosis with contamination, squamous metaplasia and pancreatic metastases from a distant squamous carcinoma is discussed. Besides, the case is an accelerated model of the adenoma(IPMN)-carcinoma sequence probably due to the CDKN2A ger-mline mutation. Somatic CDKN2A mutations are commonevents in the early steps of sporadic pancreatic cancer, but germline mutation carriers have a significantly higher risk of pancreatic carcinoma.Fernando Martínez de Juan María Reolid Escribano Carmen Martínez Lapiedra Fernanda Maia de Alcantara María Caballero Soto Ana Calatrava Fons Isidro Machado 2017World Journal of Gastrointestinal Oncology2017,9,9:1
3Aggressive angiomyxoma: a second case of metastasis with patient’s death显示文摘Stella Blandamura Julia Cruz Lourdes Faure Vergara Isidro Machado Puerto Vito Ninfo 2003Human Pathology2003,,10:1
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