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| 1 | Risk factors associated with the development of ischemic colitis显示文摘AIM:To ascertain the role of cardiovascular risk factors,cardiovascular diseases,standard treatments and other diseases in the development of ischemic colitis(IC).METHODS:A retrospective,case-control study was designed,using matched data and covering 161 incident cases of IC who required admission to our hospital from 1998 through 2003.IC was diagnosed on the basis of endoscopic findings and diagnostic or compatible his-tology.Controls were randomly chosen from a cohort of patients who were admitted in the same period and required a colonoscopy,excluding those with diagnosis of colitis.Cases were matched with controls(ratio 1:2),by age and sex.A conditional logistic regression was performed.RESULTS:A total of 483 patients(161 cases,322 con-trols)were included;mean age 75.67±10.03 years,55.9%women.The principal indications for colonos-copy in the control group were lower gastrointestinal hemorrhage(35.4%),anemia(33.9%),abdominal pain(19.9%)and diarrhea(9.6%).The endoscopic findings in this group were hemorrhoids(25.5%),diverticular disease(30.4%),polyps(19.9%)and colorectal cancer(10.2%).The following variables were associated with IC in the univariate analysis:arterial hypertension(P= 0.033);dyslipidemia(P<0.001);diabetes mellitus(P =0.025);peripheral arterial disease(P=0.004);heart failure(P=0.026);treatment with hypotensive drugs(P=0.023);angiotensin-converting enzyme inhibitors;(P=0.018);calcium channel antagonists(P=0.028);and acetylsalicylic acid(ASA)(P<0.001).Finally,the following variables were independently associated with the development of IC:diabetes mellitus[odds ratio(OR)1.76,95%confidence interval(CI):1.001-3.077,P=0.046];dyslipidemia(OR 2.12,95%CI:1.26-3.57,P=0.004);heart failure(OR 3.17,95%CI:1.31-7.68,P=0.01);peripheral arterial disease(OR 4.1,95%CI:1.32-12.72,P=0.015);treatment with digoxin(digitalis)(OR 0.27,95%CI:0.084-0.857,P=0.026);and ASA(OR 1.97,95%CI:1.16-3.36,P=0.012).CONCLUSION:The development of an episode of IC was independently associated with diabetes,dyslipid-emia,presence of heart failure,peripheral arterial dis-ease and treatment with digoxin or ASA. | Joaquín Cubiella Fernández Luisa Núez Calvo Elvira González Vázquez Maria Jesús García García Maria Teresa Alves Pérez Isabel Martínez Silva Javier Fernández Seara | 2010 | World Journal of Gastroenterology2010，16，36： | 27 |
| 2 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 3 | Mammography of ductal carcinoma in situ of the breast: Review of 909 cases with radiographic–pathologic correlations显示文摘 | Béatrice Barreau Isabelle de Mascarel Caroline Feuga Gaétan MacGrogan Marie-Hélène Dilhuydy Véronique Picot Jean-Marie Dilhuydy Christine Tunon de Lara Emmanuel Bussières I. Schreer | 2005 | European Journal of Radiology2005，，1： | 2 |
| 4 | Pharmacological properties of Anagallis arvensis L. (“scarlet pimpernel”) and Anagallis foemina Mill. (“blue pimpernel”) traditionally used as wound healing remedies in Navarra (Spain)显示文摘 | Víctor López Anna K. J?ger Silvia Akerreta Rita Yolanda Cavero Maria Isabel Calvo | 2011 | Journal of Ethnopharmacology2011，，3： | 2 |
| 5 | Cloned plasmid DNA fragments as calibrators for controlling GMOs: Different real-time duplex quantitative PCR methods显示文摘 | ISABEL T ERIK V B MARC D L | 2004 | Anal Bioanal Chem2004，378，5： | 1 |
| 6 | Hydroxyl radical mediated degradation of azo ayes: Evidence for benzene generation 显示文摘 | Spadaro J T Isabelle L Renganathan V | 1994 | Environ Sci Technol1994，28，： | 1 |
| 7 | 显示文摘 | Stephanie V Isabel P S Jorge P J | 2007 | Langmuir2007，23，： | 1 |
| 8 | Anti-pancreatic autoimmunity and Grave's disease:study of a cohort of 600 Caucasian patients显示文摘 | Didier M Franck V Isabelle G | 1997 | EurJ Endocrinol1997，137，： | 1 |
| 9 | Dynamics of rural landscapes and their main driving factors: A case study in the Seine Valley, Normandy, France 显示文摘 | Isabelle P Sabine V R | 1997 | Larutscape and Urban Planning1997，，： | 1 |
| 10 | Brain aminopeptidases and hypertension显示文摘 | Isabel P Francisco V | 2006 | J RAAS2006，7，： | 1 |
| 11 | Cytokine and C-reactive protein profiles induced by porcine circovirus type 2 experimental infection in 3- week-old piglets显示文摘 | Leanne S S Ken M C Isabelle V | 2006 | Viral humunology2006，19，2： | 1 |
| 12 | The shell microstructure, mineralogyy and isotopic composition of Amussiopecten baranensis (Pectinidae, Bivalvia) from the miocene of span: a valuable paleoenvironmental tool显示文摘 | Isabel Z Jaime D P Antonio V | 1996 | Geobios1996，29，6： | 1 |
| 13 | Retroperitoneal laparoscopic heminephrectomy in duplex kidney in infants and children: A 15-year experience 显示文摘 | MARC-DAVID D ISABELLE V ETIENNE S | 2009 | European Urology2009，，56： | 1 |
| 14 | Use of HepG2 cell line for direct or indirect mutagens screening:comparative investigation between comet and micronucleus assays显示文摘 | ISABELLE V S LUDOVIC L H JEAN-CLAUDE L | 2003 | Mut Res2003，536，： | 1 |
| 15 | Preparation of pure hectorite using microwaves显示文摘 | ISABEL V PILAR S YOLANDA C | 2010 | Physics Procedia2010，8，： | 1 |
| 16 | Transient reduction in myocardial free oxygen radical levels is involved in the improved cardiac function and structure after long-term allopurinol treatment initiated in established chronic heart failure显示文摘 | Mellin V Isabelle M Oudot A Vergely-Vandriesse C Monteil C Di Meglio B | 2005 | Eur Heart J2005，26，： | 1 |
| 17 | In Vitro Antioxidant and Anti-rhizopus Activities of Lamiaceae Herbal Extracts显示文摘 | Víctor López Silvia Akerreta Esther Casanova Jose María García-Mina Rita Yolanda Cavero María Isabel Calvo | 2007 | Plant Foods for Human Nutrition2007，，4： | 1 |
| 18 | Response surface methodology in the development of a stacking - sensitive capillary electrophoresis method for the analysis of tricyclic antidepressantsin human serum显示文摘 | Teresa G D Maria Isabel A V Nielene M D | 2005 | Eleetrophoresis2005，26，： | 1 |
| 19 | The influence of additives on the crystal habit of gibbsite显示文摘 | Isabelle S Stephane V Gerard P | 1999 | Journal of Crystal Growth1999，196，1： | 1 |
| 20 | Signal processing in the context of chaotic signals显示文摘 | womell C W Isabelle S H | 1992 | Proc IEEE ICASSP1992，，： | 1 |
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